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Volumn 82, Issue 11, 2000, Pages 1776-1782

Phase II study of the oxygen saturation curve left shifting agent BW12C in combination with the hypoxia activated drug mitomycin C in advanced colorectal cancer

Author keywords

ATP; Bioreductive agent potentiation; MRS

Indexed keywords

DEXAMETHASONE; HEMOGLOBIN; METOCLOPRAMIDE; MITOMYCIN C; OXYHEMOGLOBIN; VELARESOL;

EID: 0034035507     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2000.1138     Document Type: Article
Times cited : (3)

References (32)
  • 2
    • 0030744115 scopus 로고    scopus 로고
    • The Klaas Breur Lecture. Radiation, hypoxia and genetic stimulation: Implications for future therapies
    • Adams GE, Hasan NM and Joiner MC (1997) The Klaas Breur Lecture. Radiation, hypoxia and genetic stimulation: implications for future therapies. Radiother Oncol 44: 101-109
    • (1997) Radiother Oncol , vol.44 , pp. 101-109
    • Adams, G.E.1    Hasan, N.M.2    Joiner, M.C.3
  • 3
    • 0021247053 scopus 로고
    • Substituted benzaldehydes designed to increase the oxygen affinity of human haemoglobin and inhibit the sickling of sickle erythrocytes
    • Beddell CR, Goodford PJ, Kneen G, White RD, Wilkinson S and Wootton R (1984) Substituted benzaldehydes designed to increase the oxygen affinity of human haemoglobin and inhibit the sickling of sickle erythrocytes. Br J Pharmacol 82: 397-407
    • (1984) Br J Pharmacol , vol.82 , pp. 397-407
    • Beddell, C.R.1    Goodford, P.J.2    Kneen, G.3    White, R.D.4    Wilkinson, S.5    Wootton, R.6
  • 7
    • 0024354541 scopus 로고
    • Manipulation of oxygenation in a human tumour xenograft with BW12C or hydralazine: Effects on responses to radiation and to the bioreductive cytotoxicity of misonidazole or RSU-1069
    • Cole S and Robbins L (1989) Manipulation of oxygenation in a human tumour xenograft with BW12C or hydralazine: effects on responses to radiation and to the bioreductive cytotoxicity of misonidazole or RSU-1069. Radiother Oncol 16: 235-243
    • (1989) Radiother Oncol , vol.16 , pp. 235-243
    • Cole, S.1    Robbins, L.2
  • 8
    • 0027462417 scopus 로고
    • Pharmacokinetics of BW12C and mitomycin C, given in combination in a phase 1 study in patients with advanced gastrointestinal cancer
    • Dennis IF, Ramsay JR, Workman P and Bleehen NM (1993) Pharmacokinetics of BW12C and mitomycin C, given in combination in a phase 1 study in patients with advanced gastrointestinal cancer. Cancer Chemother Pharmacol 32: 67-72
    • (1993) Cancer Chemother Pharmacol , vol.32 , pp. 67-72
    • Dennis, I.F.1    Ramsay, J.R.2    Workman, P.3    Bleehen, N.M.4
  • 9
    • 0030054579 scopus 로고    scopus 로고
    • Phosphatidylethanolamine synthesis in the normal and lymphomatous mouse liver: A 13C NMR study
    • Dixon RM (1996) Phosphatidylethanolamine synthesis in the normal and lymphomatous mouse liver: a 13C NMR study. Anticancer Res 16: 1351-1356
    • (1996) Anticancer Res , vol.16 , pp. 1351-1356
    • Dixon, R.M.1
  • 10
    • 0025770497 scopus 로고
    • Abnormal phosphomonoester signals in 31P MR spectra from patients with hepatic lymphoma. A possible marker of liver infiltration and response to chemotherapy
    • Dixon RM, Angus PW, Rajagopalan B and Radda GK (1991) Abnormal phosphomonoester signals in 31P MR spectra from patients with hepatic lymphoma. A possible marker of liver infiltration and response to chemotherapy. Br J Cancer 63: 953-958
    • (1991) Br J Cancer , vol.63 , pp. 953-958
    • Dixon, R.M.1    Angus, P.W.2    Rajagopalan, B.3    Radda, G.K.4
  • 11
    • 0026612348 scopus 로고
    • 31P magnetic resonance spectroscopy detects a functional abnormality in liver metabolism after acetaminophen poisoning
    • Dixon RM, Angus PW, Rajagopalan B and Radda GK (1992) 31P magnetic resonance spectroscopy detects a functional abnormality in liver metabolism after acetaminophen poisoning. Hepatology 16: 943-948
    • (1992) Hepatology , vol.16 , pp. 943-948
    • Dixon, R.M.1    Angus, P.W.2    Rajagopalan, B.3    Radda, G.K.4
  • 14
    • 0029917028 scopus 로고    scopus 로고
    • Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: Correlation with sensitivity to mitomycin C and EO9
    • Fitzsimmons SA, Workman P, Grever M, Paull K, Camalier R and Lewis AD (1996) Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: correlation with sensitivity to mitomycin C and EO9. Journal of the National Cancer Institute 88: 259-269
    • (1996) Journal of the National Cancer Institute , vol.88 , pp. 259-269
    • Fitzsimmons, S.A.1    Workman, P.2    Grever, M.3    Paull, K.4    Camalier, R.5    Lewis, A.D.6
  • 15
    • 50549174560 scopus 로고
    • The determination of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent
    • Gehan A (1961) The determination of the number of patients required in a preliminary and a follow-up trial of a new chemotherapeutic agent. J Chronic Dis 13: 346-353
    • (1961) J Chronic Dis , vol.13 , pp. 346-353
    • Gehan, A.1
  • 16
    • 0031817953 scopus 로고    scopus 로고
    • Phase II study of continuous 120 h infusion of mitomycin C as salvage chemotherapy in patients with progressive or rapidly recurrent colorectal cancer
    • Hartmann JT, Harstrick A, Daikeler T, Kolimannsberger C, Muller C, Seeber S, Kanz L and Bokemeyer C (1998) Phase II study of continuous 120 h infusion of mitomycin C as salvage chemotherapy in patients with progressive or rapidly recurrent colorectal cancer. Anticancer Drugs 9: 427-431
    • (1998) Anticancer Drugs , vol.9 , pp. 427-431
    • Hartmann, J.T.1    Harstrick, A.2    Daikeler, T.3    Kolimannsberger, C.4    Muller, C.5    Seeber, S.6    Kanz, L.7    Bokemeyer, C.8
  • 17
    • 0029796904 scopus 로고    scopus 로고
    • Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack
    • Hochachka PW, Buck LT, Doll CJ and Land SC (1996) Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc Natl Acad Sci USA 93: 9493-9498.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9493-9498
    • Hochachka, P.W.1    Buck, L.T.2    Doll, C.J.3    Land, S.C.4
  • 18
    • 0025863785 scopus 로고
    • BW12C: Effects on tumour hypoxia. Tumour thermosensitivity and relative tumour and normal tissue perfusion in C3H mice
    • Honess DJ, Hu, DE and Bleehen, NM (1991) BW12C: effects on tumour hypoxia. tumour thermosensitivity and relative tumour and normal tissue perfusion in C3H mice. Br J Cancer 64: 715-722.
    • (1991) Br J Cancer , vol.64 , pp. 715-722
    • Honess, D.J.1    Hu, D.E.2    Bleehen, N.M.3
  • 19
    • 0026499916 scopus 로고
    • In vitro and in vivo studies using BW12C: Toxicity, haemoglobin modification and effects on the radiosensitivity of normal marrow and RIF-1 tumours in mice
    • Honess DJ, Nethersell AB and Bleehen NM (1992) In vitro and in vivo studies using BW12C: toxicity, haemoglobin modification and effects on the radiosensitivity of normal marrow and RIF-1 tumours in mice. Int J Radiat Biol 61: 83-94.
    • (1992) Int J Radiat Biol , vol.61 , pp. 83-94
    • Honess, D.J.1    Nethersell, A.B.2    Bleehen, N.M.3
  • 21
    • 0024273087 scopus 로고
    • Sequential treatment of progressive metastatic colorectal cancer with 5-fluorouracil/folinic acid, dipyramidole and mitomycin C
    • Migeod F, Gerlach D, Kress M, Hoffmann W, Farroukh R and Seeber S (1988) Sequential treatment of progressive metastatic colorectal cancer with 5-fluorouracil/folinic acid, dipyramidole and mitomycin C. Onkologie 2: 14-20.
    • (1988) Onkologie , vol.2 , pp. 14-20
    • Migeod, F.1    Gerlach, D.2    Kress, M.3    Hoffmann, W.4    Farroukh, R.5    Seeber, S.6
  • 22
    • 0029929226 scopus 로고    scopus 로고
    • DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines
    • Mikami K, Naito M, Tomida A, Yamada M, Sirakusa T and Tsuruo T (1996) DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines. Cancer Research 56: 2823-2826.
    • (1996) Cancer Research , vol.56 , pp. 2823-2826
    • Mikami, K.1    Naito, M.2    Tomida, A.3    Yamada, M.4    Sirakusa, T.5    Tsuruo, T.6
  • 23
    • 0026922513 scopus 로고
    • Studies of human tumors by MRS: A review
    • Negendank W (1992) Studies of human tumors by MRS: a review. NMR Biomed 5: 303-324.
    • (1992) NMR Biomed , vol.5 , pp. 303-324
    • Negendank, W.1
  • 24
    • 0027220811 scopus 로고
    • Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: A new class of bioreductive agent
    • Patterson LH (1993) Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: a new class of bioreductive agent. Cancer Metastasis Rev 12: 119-134.
    • (1993) Cancer Metastasis Rev , vol.12 , pp. 119-134
    • Patterson, L.H.1
  • 26
    • 0028097816 scopus 로고
    • Unusually marked hypoxic sensitization to indoloquinone EO9 and mitomycin C in a human colon-tumour cell line that lacks DT-diaphorase activity
    • Plumb JA and Workman P (1994) Unusually marked hypoxic sensitization to indoloquinone EO9 and mitomycin C in a human colon-tumour cell line that lacks DT-diaphorase activity. Int J Cancer 56: 134-139.
    • (1994) Int J Cancer , vol.56 , pp. 134-139
    • Plumb, J.A.1    Workman, P.2
  • 27
    • 0022624956 scopus 로고
    • Combination chemotherapy (5-fluorouracil, methyl-CCNU, mitomycin C) versus 5-fluorouracil alone for advanced previously untreated colorectal carcinoma. A phase III study of the Piedmont Oncology Association
    • Richards F, Case LD, While DR, Muss HB, Spurr CL, Jackson DV, Cooper MR, Zekan P, Cruz J, Stuart JJ and et al. (1986) Combination chemotherapy (5-fluorouracil, methyl-CCNU, mitomycin C) versus 5-fluorouracil alone for advanced previously untreated colorectal carcinoma. A phase III study of the Piedmont Oncology Association. J Clin Oncol 4: 565-570.
    • (1986) J Clin Oncol , vol.4 , pp. 565-570
    • Richards, F.1    Case, L.D.2    While, D.R.3    Muss, H.B.4    Spurr, C.L.5    Jackson, D.V.6    Cooper, M.R.7    Zekan, P.8    Cruz, J.9    Stuart, J.J.10
  • 29
    • 0026922073 scopus 로고
    • Phospholipid metabolites as indicators of cancer cell function
    • Ruiz-Cabello J and Cohen JS (1992) Phospholipid metabolites as indicators of cancer cell function. NMR Biomed 5: 226-233.
    • (1992) NMR Biomed , vol.5 , pp. 226-233
    • Ruiz-Cabello, J.1    Cohen, J.S.2
  • 31
    • 0027328452 scopus 로고
    • The experimental development of bioreductive drugs and their role in cancer therapy
    • Workman P and Stratford IJ (1993) The experimental development of bioreductive drugs and their role in cancer therapy. Cancer Metastasis Rev 12; 73-82.
    • (1993) Cancer Metastasis Rev , vol.12 , pp. 73-82
    • Workman, P.1    Stratford, I.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.