ETA-receptor blockade and ETB-receptor stimulation in experimental congenital diaphragmatic hernia

American Journal of Physiology

Volumn 278, Issue 5 PART 1, 2000, Pages

  Thébaud, Bernard ^a,b   De Lagausie, Pascal ^a   Forgues, Dominique ^e   Aigrain, Yves ^a,c   Mercier, Jean Christophe ^a   Dinh Xuan, A Tuan ^a,d  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^b HÔPITAL ANTOINE BÉCLÈRE   (France)

^c MONTPELLIER UNIVERSITY HOSPITAL   (France)

^d Assistance Publique Hôpitaux de Paris ^*  (France)

^e Centre Hospitalier Universitaire Montpellier ^*

Author keywords

Nitric oxide; Persistent pulmonary hypertension of the newborn; Vascular endothelium

Indexed keywords

ACETYLCHOLINE; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DIPYRIDAMOLE; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR AGONIST; NITRIC OXIDE; NITROPRUSSIDE SODIUM; SARAFOTOXIN S6C; VASODILATOR AGENT; ZAPRINAST;

ANIMAL MODEL; ARTICLE; BLOOD VESSEL TONE; CONGENITAL DIAPHRAGM HERNIA; CONTROLLED STUDY; DIAPHRAGM HERNIA; EXPERIMENTAL MODEL; FETUS; LUNG BLOOD FLOW; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; VASCULAR ENDOTHELIUM;

ACETYLCHOLINE; ANIMALS; ANTIHYPERTENSIVE AGENTS; CYCLIC GMP; DIPYRIDAMOLE; DISEASE MODELS, ANIMAL; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; FEMALE; HERNIA, DIAPHRAGMATIC; HYPERTENSION, PULMONARY; NITRIC OXIDE; NITROPRUSSIDE; PEPTIDES, CYCLIC; PHOSPHODIESTERASE INHIBITORS; PREGNANCY; PULMONARY CIRCULATION; PURINONES; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; SHEEP; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS; VIPER VENOMS;

EID: 0034034547     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.278.5.l923     Document Type: Article

References (43)

1. Aareechnon W and Reid L. Hypoplasia of lung with congenital diaphragmatic hernia. Br Med J 1: 230-233, 1963.
2. Adnot S, Raffestin B, Eddahibi S, Braquet P, and Chabrier P. Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia. J Clin Invest 87: 155-162, 1991.
3. Allen SW, Chatfield B, Koppenhafer S, Shaffer M, Wolfe R, and Abman SH. Circulating immunoreactive ET-1 in children with pulmonary hypertension. Am Rev Respir Dis 48: 519-522, 1993.
4. Coppola CP, Au-Fliegner M, and Gosche JR. Endothelin-1 pulmonary vasoconstriction in rats with diaphragmatic hernia. J Surg Res 76: 74-78, 1998.
5. Dinh-Xuan AT, Higenbottam TW, Clelland J, Pepke-Zaba J, Cremona G, Butt AY, Large SR, Wells FC, and Wallwork J. Impairment of endothelium-dependent pulmonary-artery relaxation in chronic obstructive lung disease. N Engl J Med 324: 1539-1547, 1991.
6. Dinh-Xuan AT, Higenbottam TW, Clelland J, Pepke-Zaba J, Cremona G, and Wallwork J. Impairment of endothelium-dependent relaxation in patients with Eisenmenger's syndrome. Br J Pharmacol 99: 9-10, 1990.
7. D'Orleans-Juste P, Telemaque S, Claing A, Ihara M, and Yano M. Human big-endothelin-1 and endothelin-1 release prostacyclin via the activation of ET1 receptors in the rat perfused lung. Br J Pharmacol 105: 773-775, 1992.
8. Dzau VJ and Gibbons GH. Endothelium and growth factors in vascular remodeling of hypertension. Hypertension 18: III115-III221, 1991.
9. Fike CD, Kaplowitz MR, Thomas CJ, and Nelin LD. Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs. Am J Physiol Lung Cell Mol Physiol 274: L517-L526, 1998.
10. ω-nitro-L-arginine attenuates endothelium-dependent pulmonary vasodilation in lambs. Am J Physiol Heart Circ Physiol 260: H1299-H1306, 1991.
11. Glick P, Stannard VA, Leach CL, Rossmann J, Hosada Y, Morin FC, Cooney DR, Allen JE, and Holm B. Pathophysiology of congenital diaphragmatic hernia. II. The fetal lamb model is surfactant deficient. J Pediatr 27: 382-388, 1992.
12. Halbower AC, Tuder RM, Franklin WA, Pollock JS, Fostermanti U, and Abman SH. Maturation-related changes in endothelial nitric oxide synthase immunolocalization in developing ovine lung. Am J Physiol Lung Cell Mol Physiol 267: L585-L591, 1994.
13. Hanson KA, Ziegler JW, Rybalkin SD, Miller JW, Abman SH, and Clarke WR. Chronic intrauterine pulmonary hypertension increases fetal lung cGMP phosphodiesterase activity. Am J Physiol Lung Cell Mol Physiol 275: L931-L941, 1998.
14. Hasunuma K, Rodman DM, O'Brien RF, and McMurtry IF. Endothelin 1 causes pulmonary vasodilation in rats. Am J Physiol Heart Circ Physiol 259: H48-H54, 1990.
15. Irish MS, Glick PL, Russel J, Kapur P, Bambini DA, Holm BA, and Steinhorn RH. Contractile properties of intralobar pulmonary arteries and veins in the fetal lamb model of congenital diaphragmatic hernia. J Pediatr Surg 33: 921-928, 1998.
16. Ivy DD, Kinsella JP, and Abman SH. Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation. J Clin Invest 93: 2141-2148, 1994.
17. Ivy DD, Kinsella JP, and Abman SH. Endothelin blockade augments pulmonary vasodilation in the ovine fetus. J Appl Physiol 81: 2481-2487, 1996.
18. Ivy DD, Parker TA, Ziegler JW, Galan HL, Kinsella JP, Tuder RM, and Abman SH. Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus. J Clin Invest 99: 1179-1186, 1997.
19. Karamanoukian HL, Click PL, and Wilkox DT. Pathophysiology of congenital diaphragmatic hernia. X. Localization of nitric oxide synthase in the intima of pulmonary artery trunks of lambs with surgically created congenital diaphragmatic hernia. J Pediatr Surg 30: 5-9, 1994.
20. Karamanoukian HL, Click PL, Wilcox DT, Rossman JE, Holm BA, and Morin FC III. Pathophysiology of congenital diaphragmatic hernia. VIII: inhaled nitric oxide requires exogenous surfactant therapy in the lamb model of congenital diaphragmatic hernia. J Pediatr Surg 30: 1-4, 1995.
21. Karamanoukian HL, Peay T, Love JE, Abdel-Rahman E, Dandonna P, Azizkhan RG, and Glick PL. Decreased pulmonary nitric oxide synthase activity in the rat model of congenital diaphragmatic hernia. J Pediatr Surg 31: 1016-1019, 1996.
22. Kobayashi H and Puri P. Plasma endothelin levels in congenital diaphragmatic hernia. J Pediatr Surg 29: 1258-1261, 1994.
23. Levin DL, Heymann MA, Kitterman JA, Gregory GA, and Phibbs RH. Persistent pulmonary hypertension of the newborn infant. J Pediatr 89: 626-630, 1976.
24. McQueston JA, Cornfield D, McMurtry IF, and Abman SH. Effects of oxygen and exogenous L-arginine on EDRF activity in fetal pulmonary circulation. Am J Physiol Heart Circ Physiol 264: H288-H294, 1993.
25. McQueston JA, Kinsella JP, Ivy DD, McMurtry IF, and Abman SH. Chronic pulmonary hypertension in utero impairs endothelium-dependent vasodilation. Am J Physiol Heart Circ Physiol 268: H288-H294, 1995.
26. Mercier J-C, Lacaze T, Storme L, Rozé JC, Dinh-Xuan AT, and Dehan M. Disease-related response to inhaled nitric oxide in newborns with severe hypoxaemic respiratory failure. French Pediatric Study Group of Inhaled NO. Eur J Pediatr 157: 747-752, 1998.
27. Moncada S, Palmer RMJ, and Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43: 109-142, 1991.
28. Morin L, Crombleholme TM, and D'Alton ME. Prenatal diagnosis and management of fetal thoracic lesions. Semin Perinatal 18: 228-253, 1994.
29. Naye RL, Shochat SJ, Withman V, and Maisels MJ. Unsuspected pulmonary vascular abnormalities associated with diaphragmatic hernia. Pediatrics 58: 902-906, 1976.
30. North AJ, Moya FR, Mysore ML, Thomas VL, Wells LB, Wu LC, and Shaul PW. Pulmonary nitric oxide synthase gene expression is decreased in a rat model of congenital diaphragmatic hernia. Am J Respir Cell Mol Biol 13: 676-682, 1995.
31. Okazaki T, Sharma HS, McCune SK, and Tibboel D. Pulmonary vascular balance in congenital diaphragmatic hernia: enhanced endothelin-1 gene expression as a possible cause of pulmonary vasoconstriction. J Pediatr Surg 33: 81-84, 1998.
32. Orton EC, Reeves JT, and Stenmark KS. Pulmonary vasodilation with structurally altered pulmonary vessels and pulmonary hypertension. J Appl Physiol 65: 2459-2467, 1988.
33. O'Toole SJ, Irish MS, Holm BA, and Click PL. Pulmonary vascular abnormalities in congenital diaphragmatic hernia. Clin Perinatal 23: 781-794, 1996.
34. Perreault T and Baribeau J. Characterization of endothelin receptors in newborn piglet lung. Am J Physiol Lung Cell Mol Physiol 268: L607-L614, 1995.
35. Roberts JD Jr, Fineman JR, Morin FC III, Shaul PW, Rimar S, Schreiber MD, Polin RA, Zwass MS, Zayek MM, Gross I, Heymann, MA, and Zapol WM. Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group. N Engl J Med 336: 605-610, 1997.
36. B receptors mediate vasoconstriction to endothelin-1 in human blood vessels. Circulation 89: 1203-1208, 1994.
37. Shetty SS, Okada T, Webb RL, DelGrande D, and Lappe RW. Functionally distinct endothelin B receptors in vascular endothelium and smooth muscle. Biochem Biophys Res Commun 191: 459-464, 1993.
38. Sokolwsky M, Ambar I, and Galron R. A novel subtype of endothelin receptors. J Biol Chem 267: 20551-20554, 1992.
39. Thebaud B, Mercier JC, and Dinh-Xuan AT. Congenital diaphragmatic hernia: a cause of persistent pulmonary hypertension which lacks an effective therapy. Biol Neonate 74: 323-336, 1998.
40. The Neonatal Inhaled Nitric Oxide Study Group. Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure. N Engl J Med 336: 597-604, 1997.
41. The Neonatal Inhaled Nitric Oxide Study Group. Inhaled nitric oxide and hypoxic respiratory failure in infants with congenital diaphragmatic hernia. Pediatrics 99: 838-845, 1997.
42. Ziegler JW, Ivy DD, Fox JJ, Kinsella JP, Clarke WR, and Abman SH. Dipyridamole, a cGMP phosphodiesterase inhibitor, causes pulmonary vasodilation in the ovine fetus. Am J Physiol Heart Circ Physiol 269: H473-H479, 1995.
43. Ziegler JW, Ivy DD, Kinsella JP, Wiggins JW, and Abman SH. cGMP phosphodiesterase inhibitors cause pulmonary vasodilation in chronic pulmonary hypertension in utero (Abstract). Pediatr Res 37: 213A, 1995.