Parasite-secreted products regulate the host response to larval Taenia crassiceps

Parasite Immunology

Volumn 22, Issue 6, 2000, Pages 297-305

  Spolski, R J ^a   Corson, J ^a   Thomas, P G ^a   Kuhn, R E ^a  

^a WAKE FOREST UNIVERSITY   (United States)

Author keywords

Cysticercosis; Cytokines; Immunoregulation

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4; PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCHEMISTRY; CELL PROLIFERATION; CESTODIASIS; CONTROLLED STUDY; CYSTICERCOSIS; CYTOKINE PRODUCTION; ELECTROPHORESIS; HOST CELL; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOREGULATION; IN VITRO STUDY; INFECTION; LARVA; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PARASITOSIS; PERITONEAL EXUDATE CELL; PRIORITY JOURNAL; SECRETION; T LYMPHOCYTE; TAENIA; TH1 CELL; TH2 CELL;

AGE FACTORS; ANIMALS; ASCITIC FLUID; CELL DIVISION; CONCANAVALIN A; CYSTICERCOSIS; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HELMINTH PROTEINS; INTERFERON TYPE II; INTERLEUKIN-4; LARVA; LYMPH NODES; MESENTERY; MICE; MICE, INBRED BALB C; T-LYMPHOCYTES; TAENIA; TIME FACTORS;

ANIMALIA; CESTODA; TAENIA; TAENIA CRASSICEPS;

EID: 0034033119     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.2000.00301.x     Document Type: Article

References (22)

1. Allen J.E. & MacDonald A.S. (1998) Profound suppression of cellular proliferation mediated by the secretions of nematodes. Parasite Immunology 20, 241-247
2. Benavides G.R., Hubby B., Grosse W.M. et al. (1995) Construction and use of a multi-competitor gene for quantitative RT-PCR using existing primer sets. Journal of Immunological Methods 181, 145-146
3. Boissier M.C., Chiocchia G., Bessis N. et al. (1995) Biphasic effect of interferon-gamma in murine collage-induced arthritis. European Journal of Immunology 25, 1184-1190
4. Bojalil R., Terrazas L.I., Govezensky T. et al. (1993) Thymus-related cellular immune mechanisms in sex associated resistance to experimental murine cysticercosis (Taenia crassiceps). Journal of Parasitology 79, 384-389
5. Chomczynski P. & Sacchi N. (1987) Single step method of RNA isolation by acid guanidium thiocyanate phenol chloroform extraction. Analytical Biochemistry 162, 156-159
6. Darji A., Beschin A., Sileghem M. et al. (1996) In vitro simulation of immunosuppression caused by Trypanosoma brucei: active involvement of gamma interferon and tumor necrosis factor in the pathway of suppression. Infection and Immunity 64, 1937-1943
7. Fragoso G., Lamoyi E., Mellor A. et al. (1998) Increased resistance to Taenia crassiceps murine cysticercosis in Qa-2 transgenic mice. Infection and Immunity 66, 760-764
8. Freeman R. (1962). Studies on the biology of Taenia crassiceps. Canadian Journal of Zoology 40, 969-990
9. Lightowlers M.W. & Rickard M.D. (1988) Excretory-secretory products of helminth parasites: effects on host immune responses. Parasitology 96 (Suppl.), S123-S166
10. Locksley R.M. (1994). Th2 cells: help for helminths. Journal of Experimental Medicine 179, 1405-1407
11. Novelli F., Bernabei P., Ozmen L. et al. (1996) Switching on of the proliferation or apoptosis of activated human T lymphocytes by IFN-γ is correlated with the differential expression of the α-and β-chains of its receptor. Journal of Immunology 157, 1935-1943
12. Pastrana D.V., Raghavan N., Fitzgerald P. et al. (1998) Filarial nematode parasites secrete a homologue of the human cytokine macrophage migration inhibitory factor. Infection and Immunity 66, 5955-5963
13. Philipp M. & Rumjaneck F.D. (1984) Antigenic and dynamic properties of helminth surface structures. Molecular and Biochemical Parasitology 10, 245-268
14. Shepherd J.C., Aitken A. & McManus D.P. (1991) A protein secreted in vivo by Echinococcus granulosus inhibits elastase activity and neutrophil chemotaxis. Molecular and Biochemical Parasitology 44, 81-90
15. Terrazas L.I., Bojalil R., Govezensky T. & Larralde C. (1998) Shift from an early protective Th1-type immune response to a late permissive Th2-type response in murine cysticercosis (Taenia crassiceps). Journal of Parasitology 84, 74-81
16. Terrazas L.I., Cruz M., Rodriguez-Sosa M. et al. (1999) Th1-type cytokines improve resistance to murine cysticercosis caused by Taenia crassiceps. Parasitology Research 85, 135-141
17. Toenjes S.A., Spolski R.J., Mooney K.A. & Kuhn R.E. (1999a) The systemic immune response of Balb/c mice infected with larval Taenia crassiceps is a mixed Th1/Th2-type response. Parasitology 118, 623-633
18. γδ T cells do not play a major role in controlling infection in experimental cysticercosis. Parasitology 119, 413-418
19. Toenjes S.A., Spolski R.J., Alexander-Miller M.A. et al. (1999c) The role of CD8+ T cells in experimental cysticercosis, submitted
20. Vaidya T., Bakhiet M., Hill K.L. et al. (1997) The gene for a T lymphocyte triggering factor from African trypanosomes. Journal of Experimental Medicine 186, 433-438
21. Villa O.F. & Kuhn R.E. (1996) Mice infected with the larvae of Taenia crassiceps exhibit a Th2-like immune response with concomitant anergy and downregulation of Th1-associated phenomena. Parasitology 112, 561-570
22. Yenbutr P. & Scott A.L. (1995) Molecular cloning of a serine proteinase inhibitor from Brugia malayi. Infection and Immunity 63, 1745-1753