Localized drug delivery using crosslinked gelatin gels containing liposomes: Factors influencing liposome stability and drug release

Journal of Biomedical Materials Research

Volumn 51, Issue 1, 2000, Pages 96-106

  DiTizio, Valerio ^a,b   Karlgard, Caroline ^a   Lilge, Lothar ^c   Khoury, Antoine E ^d,e   Mittelman, Marc W ^d   DiCosmo, Frank ^a,b,c,d  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY HEALTH NETWORK   (Canada)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Crosslinked gelatin; Device related infection; Hydrogel coated catheter ciprofloxacin; Liposomes

Indexed keywords

BIOLOGICAL MATERIALS; BIOMEDICAL EQUIPMENT; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; IMPLANTS (SURGICAL); POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES;

DEVICE RELATED INFECTION; HYDROGEL COATED CATHETER CIPROFLOXACIN; LIPOSOMES;

CONTROLLED DRUG DELIVERY;

CHLORHEXIDINE; CIPROFLOXACIN; GELATIN; LIPOSOME; MACROGOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DEVICE; DRUG DELIVERY SYSTEM; DRUG RELEASE; ELECTRON SPIN RESONANCE; ESCHERICHIA COLI; GEL; NONHUMAN; TENSILE STRENGTH; THERMOSTABILITY; URINARY TRACT INFECTION;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; ALGORITHMS; ANIMALS; ANTI-INFECTIVE AGENTS; BACTERIA; CHOLESTEROL; CIPROFLOXACIN; COMPRESSIVE STRENGTH; CROSS-LINKING REAGENTS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; ELECTRON SPIN RESONANCE SPECTROSCOPY; HYDROGELS; LIPID BILAYERS; LIPOSOMES; PHARMACEUTICAL PREPARATIONS; RABBITS; SPECTROPHOTOMETRY, ULTRAVIOLET; TENSILE STRENGTH; WATER;

EID: 0034032944     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4636(200007)51:1<96::AID-JBM13>3.0.CO;2-S     Document Type: Article

References (33)

1. Gregoriadis G, editor. Liposomes as drug carriers: Recent trends and progress. Chichester: John Wiley & Sons; 1988. 885 p.
2. Draye JP, Delaey B, van de Voorde A, van den Bulcke A, Bogdanov B, Schacht E. In vitro release characteristics of bioactive molecules from dextrandialdehyde crosslinked gelatin hydrogel films. Biomaterials 1998;19:99-107.
3. Gregoriadis G, Ryman BE. Fate of protein-containing liposomes injected into rats. An approach to the treatment of storage diseases. Eur J Biochem 1972;27:485-491.
4. Allen TM, Hansen C, Martin F, Redemann C, Yau-Young A. Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo. Biochim Biophys Acta 1991;1066:29-36.
5. Tabata Y, Hijikata S, Ikada Y. Enhanced vascularization and tissue granulation by basic fibroblast growth factor impregnated in gelatin hydrogels. J Controlled Release 1994;31:189-199.
6. Esposito E, Cortesi R, Nastruzzi C. Gelatin microspheres: Influence of preparation parameters and thermal treatment on chemico-physical and biopharmaceutical properties. Biomaterials 1996;17:2009-2020.
7. Wachol-Drewek Z, Pfeiffer M, Scholl E. Comparative investigation of drug delivery of collagen implants saturated in antibiotic solutions and a sponge containing gentamicin. Biomaterials 1996;17:1733-1738.
8. Weiner AL, Carpenter-Green SS, Soehngen EC, Lenk RP, Popescu MC. Liposome-collagen gel matrix: A novel sustained drug delivery system. J Pharm Sci 1985;74:922-925.
9. Gabrijelcic V, Sentjurc M. Influence of hydrogels on liposome stability and on the transport of liposome-entrapped substances into the skin. Int J Pharmaceut 1995;118:207-212.
10. Takagi I, Shimizu H, Yotsuyanagi T. Application of alginate gel as a vehicle for liposomes. I. Factors affecting the loading of drug-containing liposomes and drug release. Chem Pharm Bull 1996,44:1941-1947.
11. Banerjee SN, Emori TG, Culver DH. Secular trends in nosocomial primary bloodstream infection in the United States, 1980-1989. Am J Med 1991;91(3B):86S-89S.
12. Stamm WE. Guidelines for prevention of catheter-associated urinary tract infections. Ann Intern Med 1975;82:386-390.
13. Nickel JC, Ruseska I, Wright JB, Costerton JW. Tobramycin resistance of Pseudomonas aeruginosa cells growing as a biofilm on urinary catheter material. Antimicrob Agents Chemother 1985;27:619-624.
14. Ciresi DL, Albrecht RM, Volkers PA, Scholten DJ. Failure of antiseptic bonding to prevent central venous catheter-related infection and sepsis. Am Surg 1996;62:641-646.
15. Raad I, Darouiche R, Hachem R, Mansouri M, Bodey GP. The broad-spectrum activity and efficacy of catheters coated with minocycline and rifampin. J Infect Dis 1996;173:418-424.
16. DiTizio V, Ferguson GW, Mittelman MW, Khoury AE, Bruce AW, DiCosmo F. A liposomal hydrogel for the prevention of bacterial adhesion to catheters. Biomaterials 1998;19:1877-1884.
17. Pugach JL, DiTizio V, Mittelman MW, Bruce AW, DiCosmo F, Khoury AE. Antibiotic hydrogel-coated Foley catheters for prevention of urinary tract infection in a rabbit model. J Urol 1999;162:883-887.
18. Fortier G, Laliberte M. Surface modification of horseradish peroxidase with poly(ethylene glycol)s of various molecular masses. Biotech Appl Biochem 1993;17:115-130.
19. Nicholov R, DiTizio V, DiCosmo F. Interaction of paclitaxel with phospholipid bilayers. J Lipo Res 1995;5:503-522.
20. Bueche F. Physical properties of polymers. New York: John Wiley & Sons, Inc.; 1952. 354 p.
21. Hemminga MA. Interpretation of ESR and saturation transfer ESR spectra of spin labeled lipids and membranes. Chem Phys Lipids 1983;32:323-383.
22. Morimoto Y, Hosokawa M, Sayo H, Takeuchi Y. ESR study of membrane perturbation and the lysis of liposomes induced by chlorpromazine. Chem Pharm Bull 1994;42:123-129.
23. Prime KL, Whitesides GM. Adsorption of proteins onto surfaces containing end-attached oligo(ethylene oxide) - A model system using self-assembled monolayers. J Am Chem Soc 1993; 115:10714-10721.
24. Sofia SJ, Premnath V, Merrill EW. Poly(ethylene oxide) grafted to silicon surfaces: Grafting density and protein adsorption. Macromolecules 1998;31:5059-5070.
25. Harder P, Grunze M, Dahint R, Whitesides GM, Laibinis PE. Molecular conformation in oligo(ethylene glycol)-terminated self-assembled monolayers on gold and silver surfaces determines their ability to resist protein adsorption. J Phys Chem B 1998;102:426-436.
26. Favardi P, Lecharei JP, Maillardi M, Favardi N, Djabourov M, Leblond J. A technique for labeling the sample surface for quick-freeze, deep-etch, rotary replication electron microscopy: Application to the study of gelatin gel structure. Biol Cell 1989;67:201-207.
27. McEvoy H, Ross-Murphy SB, Higgins JS. Mechanical properties of chemically and physically crosslinked gelatin gels. Polym Comm 1989;30:133-135.
28. Ross-Murphy SB. Structure and rheology of gelatin gels. Imag Sci J 1997;45:205-209.
29. Chin NX, Neu HC. Ciprofloxacin, a quinoline carboxylic acid compound active against aerobic and anaerobic bacteria. Antimicrob Agents Chemother 1984;25:319-326.
30. Sherertz RJ, Carruth WA, Hampton AA, Byron MP, Solomon DD. Efficacy of antibiotic-coated catheters in preventing subcutaneous staphylococcus-aureus infection in rabbits. J Infect Dis 1993;167:98-106.
31. Zborowski J, Roerdink F, Scherphof G. Leakage of sucrose from phosphatidylcholine liposomes induced by interaction with serum albumin. Biochim Biophys Acta 1977;497:183-191.
32. Scherphof G, Roerdink F, Waite M, Parks J. Disintegration of phosphatidylcholine liposomes in plasma as a result of interaction with high-density lipoproteins. Biochim Biophys Acta 1978;542:296-307.
33. Maurer-Spurej E, Wong KF, Maurer N, Fenske DB, Cullis PR. Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients. Biochim Biophys Acta 1999;1416:1-10.