Structure of the Elk-1-DNA complex reveals how DNA-distal residues affect ETS domain recognition of DNA

Nature Structural Biology

Volumn 7, Issue 4, 2000, Pages 292-297

  Mo, Yi ^a   Vaessen, Benjamin ^a,b   Johnston, Karen ^a   Marmorstein, Ronen ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; SERUM RESPONSE FACTOR; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DNA BINDING; DNA PROTEIN COMPLEX; DNA STRUCTURE; MOLECULAR RECOGNITION; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DNA; DNA-BINDING PROTEINS; ETS-DOMAIN PROTEIN ELK-1; ETS-DOMAIN PROTEIN ELK-4; GENES, FOS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-ETS; RESPONSE ELEMENTS; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTORS;

CERVUS ELAPHUS; EUKARYOTA;

EID: 0034031280     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/74055     Document Type: Article

References (26)

1. Sharrocks, A.D., Brown, A.L., Ling, Y. & Yates, P.R. Int. J. of Biochem. Cell Biol. 29, 1371-1387 (1997).
2. Dittmer, J. & Nordheim, A. Biochim. Biophys. Acta Rev. Cancer 1377, F1-F11 (1998).
3. Graves, B.J. & Petersen, J.M. In Advances in Cancer Research (Woude, G.v.d. & Klein, G., eds., Academic Press, San Diego), 1-55 (1998).
4. Yang, S.H., Yates, P.R., Mo, Y. & Sharrocks, A.D. Gene Ther. Mol. Biol. 3, 355-371 (1998).
5. Shore, P. & Sharrocks, A.D. Eur. J. Biochem. 229, 1-13 (1995).
6. Shore, P. & Sharrocks, A.D. Nucleic Acids Res. 23, 4698-4706 (1995).
7. Shore, P. et al. Mol. Cell. Biol. 16, 3338-3349 (1996).
8. Mo, Y., Vaessen, B., Johnston, K. & Marmorstein, R. Mol. Cell 2, 201-212 (1998).
9. Brennan, R.G. Cell 74, 773-776 (1993).
10. Werner, M.H. et al. J. Biomol. NMR 10, 317-328 (1997).
11. Kodandapani, R. et al. Nature 380, 456-460 (1996).
12. Batchelor, A.H., Piper, D.E., de la Brousse, F.C., Mcknight, S.L. & Wolberger, C. Science 279, 1037-1041 (1998).
13. Donaldson, L.W., Petersen, J.M., Graves, B.J. & McIntosh, L.P. EMBO J. 15, 125-134 (1996).
14. Aggarwal, A.K. Methods Enzymol. 1, 83-90 (1990).
15. Otwinowski, Z. In Proceedings of the CCP4 Study Weekend: Data collection and Processing. (Sawyer, L., Isaacs, N. & Bailey, S., eds., SERC Daresbury Laboratory, Warrington, UK), 56-62 (1993).
16. Navaza, J. Acta Crystallogr. A 50, 157-163 (1994).
17. Brunger, A.T. X-PLOR 3.1: a system for X-ray crystallography and NMR. (Yale University Press, New Haven, Connecticut; 1992).
18. Brunger, A.T. Nature 335, 472-474 (1992).
19. Jones, T.A., Zou, J.Y. & Cowen, S.W. Acta Crystallogr. A 47, 110-119 (1991).
20. Brunger, A.T. & Krukowski, A. Acta Crystallogr. A 46, 585-593 (1990).
21. Rice, L.M. & Brunger, A.T. Proteins 19, 277-290 (1994).
22. Kleywegt, G.J. & Jones, T.A. Acta Crystallogr. D 52, 829-832 (1996).
23. Laskowski, R.A., MacArthur, M.A., Moss, D.S. & Thornton, J.M. J. Appl. Crystallogr. 26, 283-291 (1993).
24. Jiang, J.S. & Brunger, A.T. J. Mol. Biol. 243, 100-115 (1994).
25. Brunger, A.T. et al. Acta Crystallogr. D 54, 905-921 (1998).
26. Hutchinson, E.G. & Thornton, J.M. Protein Sci. 5, 212-220 (1996).