메뉴 건너뛰기




Volumn 60, Issue 3, 2000, Pages 143-154

Role of oxidative stress and glutathione in busulfan toxicity in cultured murine hepatocytes

Author keywords

Busulfan; Cell, cultured; Glutathione; Glutathione transferase; Hepatic veno occlusive disease; Hepatitis, toxic; Oxidative stress

Indexed keywords

ANTIOXIDANT; BUSULFAN; CARMUSTINE; CIBACRON BLUE F3GA; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE ISOENZYME; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSFERASE INHIBITOR;

EID: 0034025774     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000028359     Document Type: Article
Times cited : (100)

References (30)
  • 1
    • 0027172087 scopus 로고
    • Allogeneic hone marrow transplantation for acute myelogenous leukemia, acute lymphocytic leukemia, and multiple myeloma following preparation with busulfan and cyclophosphamidc (BuCy2)
    • Copelan EA, Biggs JC, Szer J, Thompson JM, Crilley P, Brodsky I, Klein JL, Kapoor N, Harman GS, Avalos BR: Allogeneic hone marrow transplantation for acute myelogenous leukemia, acute lymphocytic leukemia, and multiple myeloma following preparation with busulfan and cyclophosphamidc (BuCy2). Semin Oncol 1993;20:33-38.
    • (1993) Semin Oncol , vol.20 , pp. 33-38
    • Copelan, E.A.1    Biggs, J.C.2    Szer, J.3    Thompson, J.M.4    Crilley, P.5    Brodsky, I.6    Klein, J.L.7    Kapoor, N.8    Harman, G.S.9    Avalos, B.R.10
  • 2
    • 0023584421 scopus 로고
    • Preparative regimens for marrow transplantation containing busulphan are associated with haemorrhagic cytitis and hepatic veno-occlusive disease but a short duration of leucopenia and little oro-pharyngeal mucositis
    • Atkinson K, Biggs J, Noble G, Ashby M, Concannon A, Dodds A: Preparative regimens for marrow transplantation containing busulphan are associated with haemorrhagic cytitis and hepatic veno-occlusive disease but a short duration of leucopenia and little oro-pharyngeal mucositis. Bone Marrow Transplant 1987;2: 385-394.
    • (1987) Bone Marrow Transplant , vol.2 , pp. 385-394
    • Atkinson, K.1    Biggs, J.2    Noble, G.3    Ashby, M.4    Concannon, A.5    Dodds, A.6
  • 4
    • 0029809978 scopus 로고    scopus 로고
    • Cellular target of cyclophosphamide toxicity in the murine liver: Role of glutathione and site of metabolic activation
    • DeLeve LD: Cellular target of cyclophosphamide toxicity in the murine liver: Role of glutathione and site of metabolic activation. Hepatology 1996;24:830-837.
    • (1996) Hepatology , vol.24 , pp. 830-837
    • DeLeve, L.D.1
  • 5
    • 0026759834 scopus 로고
    • Risk factors for hepatic veno-occlusive disease after high-dose busulfan-containing regimens followed by autologous bone marrow transplantation: A study in 136 children
    • Méresse V, Hartmann O, Vassal G, Benhamou E, Valteau-Couanet D, Brugières L, Lemerle J: Risk factors for hepatic veno-occlusive disease after high-dose busulfan-containing regimens followed by autologous bone marrow transplantation: A study in 136 children. Bone Marrow Transplant 1992;10:135-141.
    • (1992) Bone Marrow Transplant , vol.10 , pp. 135-141
    • Méresse, V.1    Hartmann, O.2    Vassal, G.3    Benhamou, E.4    Valteau-Couanet, D.5    Brugières, L.6    Lemerle, J.7
  • 6
    • 0342278548 scopus 로고
    • Metabolism of myleran (1,4-dimethanesulphonyloxybutane)
    • Roberts JJ, Warwick GP: Metabolism of myleran (1,4-dimethanesulphonyloxybutane). Nature 1959;183:1509-1510.
    • (1959) Nature , vol.183 , pp. 1509-1510
    • Roberts, J.J.1    Warwick, G.P.2
  • 7
    • 0023225451 scopus 로고
    • Urinary metabolites of busulfan in the rat
    • Hassan M, Ehrsson H: Urinary metabolites of busulfan in the rat. Drug Metab Dispos 1987; 15:399-402.
    • (1987) Drug Metab Dispos , vol.15 , pp. 399-402
    • Hassan, M.1    Ehrsson, H.2
  • 8
    • 0023856517 scopus 로고
    • Biliary excretion of a glutathione conjugate of busulfan and 1,4-diiodobutane in the rat
    • Marchand DH, Remmel RP, Abdel-Monem MM: Biliary excretion of a glutathione conjugate of busulfan and 1,4-diiodobutane in the rat. Drug Metab Dispos 1988;16:85-92.
    • (1988) Drug Metab Dispos , vol.16 , pp. 85-92
    • Marchand, D.H.1    Remmel, R.P.2    Abdel-Monem, M.M.3
  • 9
    • 0029840656 scopus 로고    scopus 로고
    • Busulfan conjugation by glutathione S-transferases α, μ and π
    • Czerwinski M, Gibbs JP, Slattery JT: Busulfan conjugation by glutathione S-transferases α, μ and π. Drug Metab Dispos 1996;24:1015-1019.
    • (1996) Drug Metab Dispos , vol.24 , pp. 1015-1019
    • Czerwinski, M.1    Gibbs, J.P.2    Slattery, J.T.3
  • 10
    • 0015031220 scopus 로고
    • The effect of cysteine on the immunosuppressive activity of busulphan, cyclophosphamide and nitrogen mustard
    • Addison IE, Berenbaum MC: The effect of cysteine on the immunosuppressive activity of busulphan, cyclophosphamide and nitrogen mustard. Br J Cancer 1971;25:172-181.
    • (1971) Br J Cancer , vol.25 , pp. 172-181
    • Addison, I.E.1    Berenbaum, M.C.2
  • 11
    • 0028343551 scopus 로고
    • Dacarhazine toxicity in murine liver cells: A novel model of hepatic endothelial injury and glutathione defense
    • DeLeve LD: Dacarhazine toxicity in murine liver cells: A novel model of hepatic endothelial injury and glutathione defense. J Pharmacol Exp Ther 1994;268:1261-1270.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 1261-1270
    • DeLeve, L.D.1
  • 12
    • 0029932363 scopus 로고    scopus 로고
    • Toxicity of azathioprine and monocrotaline in murine sinuosidal endothelial cells and hepatocytes: The role of glutathionc and relevance to hepatic venooclusive disease
    • DeLeve LD, Wang X, Kuhlenkamp JF, Kaplowitz N: Toxicity of azathioprine and monocrotaline in murine sinuosidal endothelial cells and hepatocytes: The role of glutathionc and relevance to hepatic venooclusive disease. Hepatology 1996;23:589-599.
    • (1996) Hepatology , vol.23 , pp. 589-599
    • DeLeve, L.D.1    Wang, X.2    Kuhlenkamp, J.F.3    Kaplowitz, N.4
  • 13
    • 0019131878 scopus 로고
    • High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and selected thiols and disulfides
    • Reed DJ, Babson TR, Beetty DW, Brodie AE, Ellis WW, Potter DW: High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and selected thiols and disulfides. Anal Biochem 1980;106:55-62.
    • (1980) Anal Biochem , vol.106 , pp. 55-62
    • Reed, D.J.1    Babson, T.R.2    Beetty, D.W.3    Brodie, A.E.4    Ellis, W.W.5    Potter, D.W.6
  • 14
    • 0023079953 scopus 로고
    • High-performance liquid chromatography of thiols and disulfides: Dinitrophenol derivatives
    • Fariss MW, Reed DJ: High-performance liquid chromatography of thiols and disulfides: Dinitrophenol derivatives. Methods Enzymol 1987; 143:101-109.
    • (1987) Methods Enzymol , vol.143 , pp. 101-109
    • Fariss, M.W.1    Reed, D.J.2
  • 15
    • 0025797088 scopus 로고
    • Fluorimetric determination of oxidised and reduced glutathione in cells and tissues by high-performance liquid chromatography following derivatization with dansyl chloride
    • Martin J, White INH: Fluorimetric determination of oxidised and reduced glutathione in cells and tissues by high-performance liquid chromatography following derivatization with dansyl chloride. J Chromatogr A 1991;568: 219-225.
    • (1991) J Chromatogr A , vol.568 , pp. 219-225
    • Martin, J.1    White, I.N.H.2
  • 16
    • 0028923398 scopus 로고
    • Effects of N-acetyl-L-cysteine on T-cell apoptosis are not mediated by increased cellular glutathione
    • Jones DP, Maellaro E, Jiang S, Slater AFG, Orrenius S: Effects of N-acetyl-L-cysteine on T-cell apoptosis are not mediated by increased cellular glutathione. Immunol Lett 1995;45: 205-209.
    • (1995) Immunol Lett , vol.45 , pp. 205-209
    • Jones, D.P.1    Maellaro, E.2    Jiang, S.3    Slater, A.F.G.4    Orrenius, S.5
  • 17
    • 0023201142 scopus 로고
    • Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehydethiobarbituric acid adduct
    • Wong SHY, Knight JA, Hopler SM, Zaharia O, Leach CN Jr, Sunderman FW Jr: Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehydethiobarbituric acid adduct. Clin Chem 1987; 33:214-220.
    • (1987) Clin Chem , vol.33 , pp. 214-220
    • Wong, S.H.Y.1    Knight, J.A.2    Hopler, S.M.3    Zaharia, O.4    Leach C.N., Jr.5    Sunderman F.W., Jr.6
  • 18
    • 0027399578 scopus 로고
    • Lipoprotein oxidation and measurement of thiobarbituric acid reacting substances formation in a single microtiter plate: Its use for evaluation of antioxidants
    • Wallin B, Rosengren B, Shertzer HG, Camejo G: Lipoprotein oxidation and measurement of thiobarbituric acid reacting substances formation in a single microtiter plate: Its use for evaluation of antioxidants. Anal Bioehem 1993; 208:11-15.
    • (1993) Anal Bioehem , vol.208 , pp. 11-15
    • Wallin, B.1    Rosengren, B.2    Shertzer, H.G.3    Camejo, G.4
  • 20
    • 0017139982 scopus 로고
    • Enzymatic thiolysis of azathioprine in vitro
    • Kaplowitz N: Enzymatic thiolysis of azathioprine in vitro. Biochem Pharmacol 1976;25: 2421-2426.
    • (1976) Biochem Pharmacol , vol.25 , pp. 2421-2426
    • Kaplowitz, N.1
  • 21
    • 0017913266 scopus 로고
    • Inhibition of hepatic metabolism of azathioprine in vivo
    • Kaplowitz N, Kuhlenkamp JF: Inhibition of hepatic metabolism of azathioprine in vivo. Gastrocnterology 1978;74:90-92.
    • (1978) Gastrocnterology , vol.74 , pp. 90-92
    • Kaplowitz, N.1    Kuhlenkamp, J.F.2
  • 22
    • 0023766343 scopus 로고
    • Cytotoxicity of fluorine-containing alkyl alkanesulfonates to cultured leukemia L1210 cells
    • Ohta Y, Kohda K, Kimoto H, Okano T, Kawazoe Y: Cytotoxicity of fluorine-containing alkyl alkanesulfonates to cultured leukemia L1210 cells. Chem Pharm Bull 1988;36:2410-2416.
    • (1988) Chem Pharm Bull , vol.36 , pp. 2410-2416
    • Ohta, Y.1    Kohda, K.2    Kimoto, H.3    Okano, T.4    Kawazoe, Y.5
  • 23
    • 0022482922 scopus 로고
    • Comparative studies of total cross-linking, cell survival and cell cycle perturbations in Chinese hamster cells treated with alkylating agents in vitro
    • Millar BC, Tilby MJ, Ormerod MG, Payne AW, Jinks S, Loverock PS: Comparative studies of total cross-linking, cell survival and cell cycle perturbations in Chinese hamster cells treated with alkylating agents in vitro. Biochem Pharmacol 1986;35:1163-1169.
    • (1986) Biochem Pharmacol , vol.35 , pp. 1163-1169
    • Millar, B.C.1    Tilby, M.J.2    Ormerod, M.G.3    Payne, A.W.4    Jinks, S.5    Loverock, P.S.6
  • 25
    • 0021041949 scopus 로고
    • Correlations of alkylating activity and mutagenicity in bacteria of cytostatic drugs
    • Hemminki K, Kallama S, Falck K: Correlations of alkylating activity and mutagenicity in bacteria of cytostatic drugs. Ada Pharmacol Toxicol 1983;53:421-428.
    • (1983) Ada Pharmacol Toxicol , vol.53 , pp. 421-428
    • Hemminki, K.1    Kallama, S.2    Falck, K.3
  • 26
    • 0025801796 scopus 로고
    • DNA interstrand crosslinking and sequence selectivity of dimethanesulphonates
    • Ponti M, Souhami RL, Fox BW, Hartley JA: DNA interstrand crosslinking and sequence selectivity of dimethanesulphonates. Br J Cancer 1991;63:743-747.
    • (1991) Br J Cancer , vol.63 , pp. 743-747
    • Ponti, M.1    Souhami, R.L.2    Fox, B.W.3    Hartley, J.A.4
  • 28
    • 0031919721 scopus 로고    scopus 로고
    • Comparison of human liver and small intestinal glutathione S-transferase-catalyzed busulfan conjugation in vitro
    • Gibbs JP, Yang JS, Slattery JT: Comparison of human liver and small intestinal glutathione S-transferase-catalyzed busulfan conjugation in vitro. Drug Metab Dispos 1998;26:52-55.
    • (1998) Drug Metab Dispos , vol.26 , pp. 52-55
    • Gibbs, J.P.1    Yang, J.S.2    Slattery, J.T.3
  • 30
    • 0029765411 scopus 로고    scopus 로고
    • Busulfanglutathione conjugation catalyzed by human liver cytosolic glutathionc S-transferases
    • Gibbs JP, Czerwinski M, Slattery JT: Busulfanglutathione conjugation catalyzed by human liver cytosolic glutathionc S-transferases. Cancer Res 1996;56:3678-3681.
    • (1996) Cancer Res , vol.56 , pp. 3678-3681
    • Gibbs, J.P.1    Czerwinski, M.2    Slattery, J.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.