Arachidonic acid metabolism in primary irritant dermatitis produced by patch testing of human skin with surfactants

Toxicology and Applied Pharmacology

Volumn 153, Issue 1, 1998, Pages 59-67

  Muller Decker K ^a   Heinzelmann, T ^c   Furstenberger G ^a   Kecskes, A ^c   Lehmann, W D ^b   Marks, F ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b Institute for Clinical Pharmacology   (Germany)

^c BAYER PHARMA AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; BENZALKONIUM CHLORIDE; DODECYL SULFATE SODIUM; ICOSANOID; INTERLEUKIN 1ALPHA; LEUKOTRIENE B4; POLYSORBATE 80; PROSTAGLANDIN; SURFACTANT; TRIETHANOLAMINE; WATER;

ADULT; ARACHIDONIC ACID METABOLISM; ARTICLE; BLISTER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENZYME IMMUNOASSAY; EPIDERMIS; ERYTHEMA; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; IRRITANT DERMATITIS; KERATINOCYTE; MALE; MASS SPECTROMETRY; PATCH TEST; RANDOMIZED CONTROLLED TRIAL; SKIN; WATER LOSS;

EID: 0032210809     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1998.8521     Document Type: Article

References (53)

1. Agner T., and Serup J. (1990). Sodium lauryl sulfate for irritant patch testing. A dose-response study using bioengineering methods for determination of skin irritation. J. Invest. Dermatol. 95, 543-547.
2. American College of Toxicology (1983). Final report on the safety assessment of triethanolamine, diethanolamine, and monoethanolamine. Am. Coll. Toxicol. 2, 183-235.
3. Balls, M. (1994a). In vitro toxicology: Recent developments in technology and application. Tibtech. 12, 255-256.
4. Balls, M. (1994b). Replacement of animal procedures: Alternatives in research, education and testing. Lab. Anim. 28, 193-211.
5. Balls, M., Blaauboer, B., Brusick, D., Frazier, J., Lamb, D., Pemberton, M., Reinhardt, C., Roberfroid, M., Rosenkranz, H., Schmid, B., Spielmann, H., Stammati, A. L., and Walum, E. (1990). Report and recommendations of the CAAT/ERGATT workshop on the validation of toxicity test procedures. ATLA 18, 313-337.
6. Balls, M., De Klerck, W., Baker, F., Van Beek, M., Boullion, C., Bruner, L., Carstensen, J., Chamberlain, M., Cottin, M., Curren, R., Dupuis, J., Fair-weather, F., Faure, U., Fentem, J., Fisher, C., Galle, C., Kemper , F., Knaap, A., Langley, G., Loprieno, G., Loprieno, N., Pape, W., Pechovitch, G., Spielmann, H., Ungar, K., White, I., and Zuang, V. (1995a). Development and validation of non-animal tests and testing strategies: The identification of a coordinated response to the challenge and the opportunity presented by the sixth amendment to the cosmetics directive (76/768/EEC). ATLA 23, 398-409.
7. Balls, M., Goldberg, A. M., Fentem, J. H., Broadhead, C. L., Burch, R. L., Festing, M. F. W., Frazier, J. M., Hendrikson, C. F. M., Jennings, M., van der Kamp, M. D. O., Morton, D. B., Rowan, A. N., Russell, C., Russell, W. M. S., Spielmann, H., Stephens, M. L., Stokes, W. S., Straughan, D. W., Yager, J. D., Zurlo, J., and van Zutphen, B. F. M. (1995b). The three Rs: The way forward. ATLA 23, 838-866.
8. Barker, J. N. W. N., Mitra, R. S., Griffiths, C. E. M., Dixit, V. M., and Nickoloff, B. J. (1991). Keratinocytes as initiators of inflammation. Lancet 337, 211-214.
9. Bonta, I. L., and Parnham, M. J. (1978). Prostaglandins and chronic inflammation. Biochem. Pharmacol. 27, 1611-1623.
10. Cohen, G., Dossou, G., Rougier, A., and Rogan, R. (1991). Measurement of inflammatory mediators induced by human keratinocytes in vitro - A protocol assessment of cutaneous irritation. Toxicol. In Vitro 5, 407-410.
11. Cunningham, F. (1990). Lipid mediators in inflammatory skin disorders. J. Lipid Med. 2, 61-74.
12. Dennis, E. A. (1997). The growing phospholipase A2 superfamily of signal transduction enzymes. TIBS 22, 1-2.
13. Draize, J. H., Woodard, G., and Calvery, H. O. (1944). Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J. Pharmacol. Exp. Ther. 82, 377-390.
14. Dykes, P. J., Edwards, M. J., O'Donovan, M. R., Merrett, V., Morgan, H. E., and Marks, R. (1991). In vitro reconstruction of human skin. The use of skin equivalent as potential indicators of cutaneous toxicity. Toxicol. In Vitro 5, 1-8.
15. Endres, S., Cannon, J. G., Ghorbani, R., Dempsey, R. A., Sisson, S. D., Lonnemann, G., Van der Meer, J. W. M., Wolff, S. M., and Dinarello, C. A. (1989). In vitro production of IL-1 beta, IL-1 alpha, TNF and IL 2 in healthy subjects: Distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation Eur. J. Immunol. 19, 2327-2333.
16. Ford-Hutchinson, A. W. (1994). Regulation of leukotriene biosynthesis. Cancer Metastasis Rev. 13, 257-267.
17. Frosch, P. J., and Kligman, A. M. (1979). The Duhring chamber test. Contact Dermatitis 15, 73-81.
18. Fürstenberger, G. (1990). Role of eicosanoids in mammalian skin epidermis. Cell Biol. Rev. 24, 1-111.
19. Gay R., Swiderek M., Nelson D., and Ernesti A. (1992). The living skin equivalent as a model in vitro for ranking the toxic potential of dermal irritants. Toxicol. In Vitro 6, 303-315.
20. Goldberg, A. M., Frazier, J. M., Brusick, D., Dickens, M. S., Flint, O., Gettings, S. D., Hill, R. N., Lipnick, R. L., Renskers, K. J., Bradlaw, J. A., Scala, R. A., Veronesi, B., Green, S., Wilcox, N. L., and Curren, R. D. (1993). Framework for validation and implementation of in vitro toxicity tests: Report of the validation and technology transfer committee of the Johns Hopkins Center for alternatives to animal testing. J. Am. Coll. Toxicol. 12, 23-30.
21. 2 in human skin. Am. J. Physiol. 270, C1037-C1050.
22. Hauser, C., Saurat, J. H., Schmitt, A., Jaunin, F., and Dayer, J. M. (1986). Interleukin 1 is present in normal human epidermis. J. Immunol. 136, 3317-3323.
23. Herzinger T., Korting H. C., and Maibach H. I. (1995). Assessment of cutaneous and occular irritancy: A decade of research on alternatives to animal experimentation. Fundam. Appl. Toxicol. 24, 29-41.
24. Janssen-Timmen U., Vickers P. J., Wittig U., Lehmann W. D., Stark H. J., Fusenig N. E., Rosenbach, T., Radmark, O., Samuelsson, B., and Habenicht, A. J. R. (1995). Expression of 5-lipoxygenase in differentiating human skin keratinocytes. Proc. Natl. Acad. Sci. USA 92, 6966-6970.
25. Juhlin, L., Civier, A., Shroot, S., and Hensby, C. (1983). Effect of infrared irradiation on the recoverable levels of free arachidonic acid and prostaglandins in human forearm skin. J. Invest. Dermatol. 81, 297-300.
26. Knott, I., Raes, M., Dieu, M., Lenoir, G., Burton, M., and Remade, J. (1993). Routine prostaglandin assay by GC-MS in multiwell tissue culture plates: Application to human synoviocytes and chondrocytes. Anal. Biochem. 210, 360-365.
27. Koeter, H. B. W. M. (1994). Principles for a pragmentic approach to the regulatory acceptance of alternative tests. Toxicol. In Vitro 4, 925-930.
28. Krieg, P., Kinzig, A., Ress-Löschke, M., Vogel, S., Vanlandingham, B., Stephan, M., Lehmann, W. D., Marks, F., and Fürstenberger, G. (1995). 12-Lipoxygenase isoenzymes in mouse skin tumor development. Mol. Carcinog. 14, 118-129.
29. Kupper, T. S., and Groves, R. W. (1995). The interleukin-1 axis and cutaneous inflammation. J. Invest. Dermatol. 105, 62S-66S.
30. Lawlor, F., Smith, N. P., Camp, R. D. R., Bacon, K. B., Kobza Black, A., Greaves, M. W., and Gearing, A. J. H. (1990). Skin exudate levels of interleukin 6, interleukin 1 and other cytokines in mycosis fungoides. Br. J. Dermatol. 123, 297-304.
31. Lawrence J. N. (1997). Application of in vivo human skin models to dermal irritancy: A brief overwiew and future prospects. Toxicol. In Vitro 11, 305-312.
32. 2 release in human and rat keratinocytes. Carcinogenesis 16, 1247-1251.
33. 2 release in human skin keratinocyte cultures. Toxicol. In Vitro 11, 627-631.
34. Lee, C. H., and Maibach, H. I. (1995). The sodium lauryl sulfate model: An overview. Contact Dermatitis 33, 1-7.
35. Lehmann, W. D., Metzger, K., Stephan, M., Wittig, U., Zalan, I., Habenicht, A. J., and Fürstenberger, G. (1994). Quantitative lipoxygenase product profiling by gas chromatography negative-ion chemical ionization mass spectrometry. Anal. Biochem. 224, 227-234.
36. Lehmann, W. D., Stephan, M., and Fürstenberger, G. (1992). Profiling assay for lipoxygenase products of linoleic and arachidonic acid by gas chromatography-mass spectrometry. Anal. Biochem. 204, 158-170.
37. Luger T. A., and Schwarz T. (1990). Evidence for an epidermal cytokine network. J. Invest. Dermatol. 95, 100S-1004S.
38. Müller-Decker, K., Fürstenberger, G., and Marks, F. (1992). Development of an in vitro alternative assay to the Draize skin irritancy test using human keratinocyte-derived proinflammatory key mediators and cell viability as test parameters. In Vitro Toxicol. 5, 191-209.
39. Müller-Decker, K., Fürstenberger, G., and Marks, F. (1994). Keratinocyte-derived proinflammatory key mediators and cell viability as in vitro parameters of irritancy: A possible alternative to the Draize skin irritation test. Toxicol. Appl. Pharmacol. 127, 99-108.
40. Nixon, G. A., Tyson, C. A., and Wertz W. C. (1975). Interspecies comparisons of skin irritancy. Toxicol. Appl. Pharmacol. 31, 481-490.
41. OECD (1981). Acute dermal irritation/corrosion. In OECD Guidelines for Testing of Chemicals. Adopted 12, no. 404, OECD, Paris.
42. Osborne, R., and Perkins M. A. (1991). In vitro skin irritation testing with human skin cell cultures. Toxicol. In Vitro 5, 563-567.
43. Powell, W. S. (1982). Rapid extraction of arachidonic acid metabolites from biological samples using octadecylsilyl silica. Methods Enzymol. 86, 467-477.
44. Rosenbach, T., Czernielewski, J., Hecker, M., and Czarnetzki, B. (1990). Comparison of eicosanoid generation by highly purified human Langerhans cells and keratinocytes. J. Invest. Dermatol. 95, 104-107.
45. Ruzicka, T. (1990). Eicosanoids in inflammatory skin diseases in Eicosanoids and the skin. (0T. Ruzicka, Ed.), pp 53-66. CRC Press, Boca Raton, FL.
46. Samuelsson B., Dahlen S. E., Lindgren J. A., Rouzer C. A., and Serhan C. N. (1987). Leukotrienes and lipoxins: Structures, biosynthesis, and biological effects. Science (Washington, D.C.) 237, 1171-1176.
47. Scholz, K., Fürstenberger, G., Müller-Decker, K., and Marks, F. (1995). Differential expression of prostaglandin H synthase in normal and activated keratinocytes in vivo and in vitro. Biochem. J. 309, 263-269.
48. Smith, W. L., and DeWitt, D. L. (1996). Prostaglandin endoperoxide H synthase-1 and -2. Adv. Immunol. 62, 167-214.
49. Sondergaard, J., Greaves, J., and Jorgensen, H. P. (1974). Recovery of prostaglandins in human primary irritant dermatitis. Arch. Dermatol. 110, 556-561.
50. van de Sandt, J. J. M., Maas, W. J., Doornick, P. C., and Rutten, A. A. (1995). Release of arachidonic and linoleic acid metabolites in skin organ cultures as characteristics of in vitro skin irritancy. Fundam. Appl. Toxicol. 25, 20-28.
51. Weil, C. S., and Scala, R. A. (1971). Study of intra-and interlaboratory variability in the results of rabbit eye and skin irritation tests. Toxicol. Appl. Pharmacol. 19, 276-360.
52. Wilhelm, K. P., Saunders, J. C., and Maibach H. I. (1989). Quantitation of sodium lauryl sulfate dermatitis in man: Comparison of four techniques: Skin colour reflectance, transepidermal water loss, laser Doppler flow measurement and visual scores. Arch. Dermatol. Res. 281, 293-295.
53. York, M., Griffiths, H. A., Whittle, E., and Basketter, D. A. (1996). Evaluation of a human patch test for the identification and classification of skin irritation potential. Contact Dermatitis 34, 204-212.