Variability of invariant mouse CD3ε chains detected by anti-CD3 antibodies

European Journal of Immunology

Volumn 30, Issue 5, 2000, Pages 1469-1479

  Criado, Gabriel ^a   Feito, Maria José ^a   Ojeda, Gloria ^b   Sánchez, Alejandra ^a   Janeway Jr , Charles A ^c   Portolés, Pilar ^b   Rojo, José M ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CD3; CD3 ; TCR

Indexed keywords

CD3 ANTIGEN; METALLOPROTEINASE; MONOCLONAL ANTIBODY CD3; PROTEINASE INHIBITOR; T LYMPHOCYTE RECEPTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIBODY AFFINITY; ANTIGEN RECOGNITION; ANTIGENIC VARIATION; ARTICLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

ALLELES; ANIMALS; ANTIGENS, CD3; MICE; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; VARIATION (GENETICS);

EID: 0034023729     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(200005)30:5<1469::AID-IMMU1469>3.0.CO;2-V     Document Type: Article

References (47)

1. Ashwell, J. D. and Klausner, R. D., Genetic and mutational analysis of the T-cell antigen receptor. Annu. Rev. Immunol. 1990. 8: 139-167.
2. Clevers, H., Alarcón, B., Wileman, T. and Terhorst, C., The T cell receptor/CD3 complex: A dynamic protein ensemble. Annu. Rev. Immunol. 1988. 6: 629-662.
3. Janeway Jr., C. A., The T cell receptor as a multicomponent signaling machine: CD4/CD8 Co-receptors and CD45 in T cell activation. Annu. Rev. Immunol. 1992. 10: 645-674.
4. Malissen, B. and Schmitt-Verhulst, A.-M., Transmembrane signaling through the T-cell-receptor-CD3 complex. Curr. Opin. Immunol. 1993. 5: 324-333.
5. Dembic, Z., Haas, W., Weiss, S., McCubrey, J., Kiefer, H., von Boehmer, H. and Steinmetz, M., Transfer of specificity by murine α and β T-cell receptor genes. Nature 1986. 320: 232-238.
6. Garcia, K. C., Degano, M., Stanfield, R. L., Brunmark, A., Jackson, M. R., Peterson, P. A., Teyton, L. and Wilson, I. A., An αβ T cell receptor structure at 2.5 Å and its orientation in the TCR-MHC complex. Science 1996. 274: 209-219.
7. Tunnacliffe, A., Buluwela, L. and Rabbits, T. H., Physical linkage of three CD3 genes on human chromosome 11. EMBO J. 1987. 6: 2953-2957.
8. Saito, H., Koyama, T., Georgopoulos, K., Clevers, H., Haser, W. G., LeBien, T., Tonegawa, S. and Terhorst, C., Close linkage of the mouse and human CD3-γ and δ-chain genes suggests that their transcription is controlled by common regulatory elements. Proc. Natl. Acad. Sci. USA 1987. 84: 9131-9134.
9. Letourneur, F. and Klausner, R. D., Activation of cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 ε. Science 1992. 255: 79-82.
10. Manolios, N., Letorneur, F., Bonifacino, J. S. and Klausner, R. D., Pairwise, cooperative and inhibitory interactions describe the assembly and probable structure of the T-cell antigen receptor. EMBO J. 1991. 10: 1643-1651.
11. Koning, F., Maloy, W. E. and Coligan, J. E., The implications of subunit interactions for the structure of the T cell receptor-CD3 complex. Eur. J. Immunol. 1990. 20: 299-305.
12. Alarcón, B., Ley, S. C., Sánchez-Madrid, F., Blumberg, R. S., Ju, S. T., Fresno, M. and Terhorst, C., The CD3-γ and CD3-δ subunits of the T cell antigen receptor can be expressed within distinct functional TCR/CD3 complexes. EMBO J. 1991. 10: 903-912.
13. San José, E., Sahuquillo, A. G., Bragado, R. and Alarcón, B., Assembly of the TCR/CD3 complex: CD3ε/δ and CD3ε/γ dimers associate indistinctly with both TCRα and TCRβ chains. Evidence for a double TCR heterodimer model. Eur. J. Immunol. 1998. 28: 12-21.
14. Meuer, S., Acuto, O., Hussey, R. E., Hodgdon, J. C., Fitzgerald, K. A., Schlossman, S. F. and Reinherz, E. L., Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor. Nature 1983. 303: 808-810.
15. Portolés, P., Rojo, J., Golby, A., Bonneville, M., Gromkowski, S., Greenbaum, L., Janeway, Jr., C. A., Murphy, D. B. and Bottomly, K., Monoclonal antibodies to murine CD3ε define distinct epitopes, one of which may interact with CD4 during T cell activation. J. Immunol. 1989. 142: 4169-4175.
16. Blumberg, R. S., Ley, S., Sancho, J., Lonberg, N., Lacy, E., McDermott, F., Schad, V., Greenstein, J. L. and Terhorst, C., Structure of the T-cell antigen receptor: evidence for two CD3 ε subunits in the T-cell receptor complex. Proc. Natl. Acad. Sci. USA 1990. 87: 7220-7224.
17. de la Hera, A., Müller, U., Olsson, C., Isaaz, S. and Tunnacliffe, A., Structure of the T cell antigen receptor (TCR): two CD3ε sub-units in a functional TCR/CD3 complex. J. Exp. Med. 1991. 173: 7-17.
18. Fernández-Miguel, G., Alarcón, B., Iglesias, A., Bluethmann, H., Alvarez-Mon, M., Sanz, E. and de la Hera, A., Multivalent structure of an αβ T cell receptor. Proc. Natl. Acad. Sci. USA 1999. 96: 1547-1552.
19. Borroto, A., Mallabiabarrena, A., Albar, J. P., Martínez-A. C. and Alarcón, B., Characterization of the region involved in CD3 pairwise interactions within the T cell receptor complex. J. Biol. Chem. 1998. 273: 12807-12816.
20. Meuer, S. C., Cooper, D. A., Odgdon, J. C., Hussey, R. E., Fitzgerald, K. A., Schlossman, S. F. and Reinherz, E. L., Identification of the antigen/MHC receptor on human inducer T lymphocytes. Science 1983. 222: 1239-1242.
21. Clevers, H., Dunlap, S., Saito, H., Georgopoulos, K., Wileman, T. and Terhorst, C., Characterization and expression of the murine CD3-ε gene. Proc. Natl. Acad. Sci. USA 1988. 85: 8623-8627.
22. Clevers, H. C., Dunlap, S., Wileman, T. E. and Terhorst, C., Human CD3-ε gene contains three miniexons and is transcribed from a non-TATA promoter. Proc. Natl. Acad. Sci. USA 1988. 85: 8156-8160.
23. Wang, J., Lim, K., Smoylar, A., Teng, M., Liu, J., Tse, A. G. D., Liu, J., Hussey, R. E., Chishti, Y., Thomson, C. T., Sweet, R. M., Nathenson, S. G., Chang, H.-C., Sacchettini, J. C. and Reinherz, E. L., Atomic structure of an αβ T cell receptor (TCR) heterodimer in complex with an anti-TCR Fab fragment derived from a mitogenic antibody. EMBO J. 1998. 17: 10-26.
24. Dianzani, U., Shaw, A., Al-Ramadi, B. K., Kubo, R. T. and Janeway Jr., C. A., Physical association of CD4 with the T cell receptor. J. Immunol. 1992. 148: 678-688.
25. Dietrich, J., Neising, A., Hou, X., Wegener, A.-M. K., Gajhede, M. and Geisler, C., Role of CD3γ in T cell receptor assembly. J. Cell Biol. 1996. 132: 299-310.
26. Göbel, T. W. F. and Fluri, M., Identification and analysis of the chicken CD3ε gene. Eur. J. Immunol. 1997. 27: 194-198.
27. Manolios, N., Kemp, O. and Li, Z. G., The T cell antigen receptor α and β chains interact via distinct regions with CD3 chains. Eur. J. Immunol. 1994. 24: 84-92.
28. Li, S., Satoh, T., Korngold, R. and Huang, Z., CD4 dimerization and oligomerization: implications for T-cell function and structure-based drug design. Immunol. Today 1998. 19: 455-462.
29. Saizawa, K., Rojo, J. M. and Janeway, C. A., Jr., Evidence for a physical association of CD4 and the CD3:α:β T-cell receptor. Nature 1987. 328: 260-263.
30. Janeway Jr., C. A., Dianzani, U., Portolés, P., Rath, S., Reich, E. P., Rojo, J. M., Yagi, J. and Murphy, D. B., Cross-linking and conformational change in T cell receptors: Role in activation and repertoire selection. Cold Spring Harb. Symp. Quant. Biol. 1989. 54: 657-666.
31. Alam, S. M., Davies, G. M., Lin, C. M., Zal, T., Nasholds, W., Jameson, S. C., Hogquist, K. A., Gascoigne, N. R. J. and Travers, P. J., Quantitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. Immunity 1999. 10: 227-237.
32. Kishimoto, H., Kubo, R. T., Yorifuji, H., Nakayama, T., Asano, Y. and Tada, T., Physical dissociation of the TCR-CD3 complex accompanies receptor ligation. J. Exp. Med. 1995. 182: 1997-2006.
33. + T cell line is activated by syngeneic antigen presenting cells in the absence of antigen. Cell. Immunol. 1995. 164: 265-278.
34. Wigzell, H., Specific affinity fractionation of lymphocytes using glass or plastic bead columns. Scand. J. Immunol. 1976. 5, Suppl. 5: 23-30.
35. + mouse T lymphocytes. Eur. J. Immunol. 1996. 26: 1228-1234.
36. Springer, T., Galfré, G., Secher, D. S. and Milstein, C., Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur. J. Immunol. 1979. 9: 301-306.
37. Forni, L. and de Petris, S., Use of fluorescent antibodies in the study of lymphoid cell membrane molecules. Methods Enzymol. 1984. 108: 413-425.
38. Yagi, J., Baron, J., Buxser, S. and Janeway Jr., C. A., Bacterial proteins that mediate the association of a defined subset of T cell receptor: CD4 complexes with class II MHC. J. Immunol. 1990. 144: 892-901.
39. Rojo, J. M., Kerner, J. D. and Janeway, C. A., Jr., Selective induction of growth factor production and growth factor receptor expression by different signals to a single T cell. Eur. J. Immunol. 1989. 19: 2061-2067.
40. Hong, S.-C., Chelouche, A., Lin, R., Shaywitz, D., Braunstein, N. S., Glimcher, L. and Janeway, C. A., An MHC interaction site maps to the amino-terminal half of the T cell receptor α chain variable domain. Cell 1992. 69: 999-1009.
41. Hong, S.-C., Sant' Angelo, D. B., Dittel, B. N., Medzhitov, R., Yoon, S. T., Waterbury, P. G. and Janeway Jr., C. A., The orientation of a T cell receptor to its MHC class II peptide ligands. J. Immunol. 1997. 159: 4395-4402.
42. Kaye, J., Porcelli, S., Tite, J., Jones, B. and Janeway Jr., C. A., Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells. J. Exp. Med. 1983. 158: 836-856.
43. Dittel, B. N., Sant' Angelo, D. B. and Janeway, C. A. Jr., Peptide antagonists inhibit proliferation and the production of IL-4 and/or IFN-γ in T helper 1, T helper 2, and T helper 0 clones bearing the same TCR. J. Immunol. 1997. 158: 4065-4073.
44. Staerz, U. D., Rammensee, H. G., Benedetto, J. D. and Bevan, M. J., Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor. J. Immunol. 1985. 134: 3994-4000.
45. Leo, O., Foo, M., Sachs, D. H. and Samelson, L., Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc. Natl. Acad. Sci. USA 1987. 84: 1374-1378.
46. + thymocytes. Nature 1987. 330: 170-173.
47. Coulie, P. G., Uyttenhove, C., Wauters, P., Manolios, N., Klausner, R. D., Samelson, L. E. and Van Snick, J., Identification of a murine monoclonal antibody specific for an allotypic determinant on mouse CD3. Eur. J. Immunol. 1991. 21: 1703-1709.