Role of CD3γ in T cell receptor assembly

Journal of Cell Biology

Volumn 132, Issue 3, 1996, Pages 299-310

  Dietrich, Jes ^a   Neisig, Anne ^a   Hou, Xiaohong ^a   Wegener, Anne Marie K ^a   Gajhede, Michael ^b   Geisler, Carsten ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CD3 ANTIGEN; T LYMPHOCYTE RECEPTOR; TUNICAMYCIN;

ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; GENE DELETION; GLYCOSYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD3; BIRDS; CELL MEMBRANE; COMPUTER SIMULATION; CYTOSOL; HUMANS; MACROMOLECULAR SUBSTANCES; MICE; MODELS, MOLECULAR; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RATS; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; SEQUENCE HOMOLOGY, AMINO ACID; SHEEP; T-LYMPHOCYTES;

EID: 0029670724     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.132.3.299     Document Type: Article

References (61)

1. Alcover, A., R. A. Mariuzza, M. Ermonval, and O. Acuto. 1990. Lysine 271 in the transmembrane domain of the T-cell antigen receptor β chain is necessary for its assembly with the CD3 complex but not for α/β dimerization. J Biol Chem 265 4131-4135.
2. Berkhout, B , B. Alarcon, and C. Terhorst. 1988. Transfection of genes encoding the T cell receptor-associated CD3 complex into COS cells results in assembly of a macromolecular structure. J Biol. Chem. 263:8528-8535.
3. Blumberg, R S., B. Alarcon, J. Sancho, F V. McDermott, P. Lopez, J Breitmeyer, and C. Terhorst. 1990. Assembly and function of the T cell antigen receptor Requirement of either the lysine or arginine residues in the transmembrane region of the α chain. J. Biol. Chem. 265:14036-14043.
4. Bonifacino, J. S . C. Chen, J. Lippincott Schwartz, J. D. Ashwell, and R. D. Klausner. 1988. Subunit interactions within the T-cell antigen receptor: clues from the study of partial complexes Proc Natl. Acad Sci. USA. 85: 6929-6933.
5. Bonifacino, J. S., C. K. Suzuki, J. Lippincott-Schwartz, A. M. Weissman, and R. D. Klausner. 1989. Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly. J Cell Biol. 109:73-83.
6. Brenner, M. B., I. S. Trowbridge, and J. L. Strominger. 1985 Cross-linking of human T cell receptor proteins: Association between the T cell idiotype β subunit and the T3 glycoprotein heavy subunit. Cell. 40:183-190.
7. Buferne, M., F. Luton, F. Letourneur, A Hoeveler, D. Couez, M. Barad, B. Malissen, A. M. Schmitt Verhulst, and C Boyer. 1992. Role of CD3 delta in surface expression of the TCR/CD3 complex and in activation for killing analyzed with a CD3 delta-negative cytotoxic T lymphocyte variant. J. Immunol. 148:657-664.
8. Carson, G. R., R. E. Kuestner, A. Ahmed, C. L. Pettey, and M F. Concino. 1991. Six chains of the human T cell antigen receptor CD3 complex are necessary and sufficient for processing the receptor heterodimer to the cell surface. J. Biol. Chem. 266:7883-7887.
9. Caspar-Bauguil, S., J. Arnaud, C. Gouaillard, X. Hou, C. Geisler, and B Rubin. 1994. Functionally important amino acids in the TCR revealed by immunoselection of membrane TCR-negative T cells. J. Immunol. 152: 5288-5298
10. Chothia, C., D. R. Boswell, and A. M. Lesk. 1988. The outline structure of the T-cell α/β receptor. EMBO (Eur Mol. Biol. Organ.) J. 7(12) 3745-3755.
11. Chou, P. Y., and G. D. Fasman. 1979 Prediction of β-turns Biophys J. 26: 367-373
12. Clevers, H., B. Alarcon, T. Wileman, and C Terhorst. 1988. The T cell receptor/CD3 complex: a dynamic protein ensemble. Annu. Rev. Immunol 6:629-662.
13. Cosson, P., S. P. Lankford, J. S Bonifacino, and R. D. Klausner. 1991. Membrane protein association by potential intramembrane charge pairs. Nature (Lond.). 351:414-416.
14. Dayhoff, M. O., R. V. Eck, and C. M. Park. 1972. A model of evolutionary change in proteins. Atlas of protein sequence and structure, 89-99.
15. Dembic, Z., W. Haas, S. Weiss, J. McCubrey, H. Kiefer, H von Boehmer, and M. Steinmetz. 1986. Transfer of specificity by murine a α and β T-cell receptor genes. Nature (Lond) 320:232-238
16. Dietrich, J., X. Hou, A. M. Wegener, and C. Geisler 1994. CD3 gamma contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor. EMBO (Eur. Mol. Biol. Organ.) J. 13: 2156-2166.
17. Dill, K. A. 1990. Dominant forces in protein folding. Biochemistry. 29: 7133-7155.
18. Geisler, C 1992. Failure to synthesize the CD3-gamma chain. Consequences for T cell antigen receptor assembly, processing, and expression. J. Immunol 148.2437-2445.
19. Geisler, C , T. Plesner, G. Pallesen, K. Skjødt, N. Ødum, and J. K. Larsen. 1988. Characterization and expression of the human T cell receptor-T3 complex by monoclonal antibody F101.01 Scand. J. Immunol. 27:685-696.
20. Geisler, C., J. Scholler, M A Wahi, B. Rubin, and A. Weiss. 1990. Association of the human CD3-ζ chain with the α β-T cell receptor/CD3 complex. Clues from a T cell variant with a mutated T cell receptor-α chain. J. Immunol. 145:1761-1767.
21. 2 homodimer J Immunol. 148:3469-3477
22. Gold, D. P., H. Clevers, B. Alarcon, S. Dunlap, J. Novotny, A. F. Williams, and C. Terhorst. 1987. Evolutionary relationship between the T3 chains of the T-cell receptor complex and the immunoglobulin supergene family Proc. Natl. Acad. Sci. USA. 84.7649-7653
23. Hall, C., B. Berkhout, B Alarcon, J. Sancho, T. Wileman, and C. Terhorst. 1991. Requirements for cell surface expression of the human TCR/CD3 complex in non-T cells. Intl. Immunol. 3:359-368
24. Hou, X., J. Dietrich, J. Kuhlmann, A. K. Wegener, and C. Geisler. 1994. Structure of the T cell receptor in a TiαVβ2, αVβ8 positive cell line. Eur. J. Immunol. 24:1228-1233.
25. Janin, J., and C. Chothia. 1990. The structure of protein-protein recognition sites. J. Biol. Chem. 265:16027-16030.
26. John, S., G. S Banting, P. N. Goodfellow, and M. J. Owen. 1989. Surface expression of the T cell receptor complex requires charged residues within the α chain transmembrane region. Eur. J. Immunol. 19:335-339.
27. Kabsch, W , and C. Sander. 1983. Dictionary of protein secondary structure: Pattern recognition of hydrogen bonded and geometrical features. Biopolymers. 22:2577-2637.
28. Kearse, K. P., D. B. Williams, and A. Singer. 1994 Persistence of glucose residues on core oligosaccharides prevents association of TCR alpha and TCR beta proteins with calnexin and results specifically in accelerated degradation of nascent TCR alpha proteins within the endoplasmic reticulum. EMBO (Eur. Mol. Biol. Organ.) J. 13:3678-3686.
29. Kim, K., T. Adachi, P. J. Nielsen, M. Terashima, M. C. Lamers, G. Kohler, and M. Reth. 1994. Two new proteins preferentially associated with membrane immunoglobulin. EMBO (Eur. Mol. Biol. Organ.) J. 13:3793-3800.
30. Klausner, R. D., J. Lippincott-Schwartz, and J. S. Bonifacino. 1990. Architectural editing. Regulating the surface expression of the multicomponent T-cell antigen receptor. Curr. Top. Membr. Transp. 36:31-51
31. Koning, F., W. L Maloy, and J. E. Coligan. 1990. The implications of subunit interactions for the structure of the T cell receptor-CD3 complex Eur. J Immunol. 20:299-305.
32. Kornfeld, R , and S. Kornfeld. 1985. Assembly of asparagine-linked oligosaccharides. Annu Rev. Biochem. 54:631-664.
33. Krissansen, G. W., M. J. Owen, W Verbi, and M. J. Crumpton. 1986. Primary structure of the T3 γ subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 γ and δ subunits. EMBO (Eur. Mol. Biol. Organ.) J. 5:1799-1808.
34. Kuhlmann, J., and C. Geisler. 1993. Structure of the T-cell receptor in a Tiαβ, Tiγδ double positive T-cell line. Scand. J. Immunol. 37:271-275
35. Kuma, K., N. Iwabe, and T. Miyala. 1991. The Immunoglobulin family. Curr. Opin. Struct. Biol. 1:384-393.
36. Kyte, J., and R F. Doolittle. 1982. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:105-132.
37. Laskowski, R. A., M. W. MacArthur, D. S. Moss, and J. M. Thornton. 1995. PROCHECK, a program to check the stereochemistry of protein structures. J. Appl Cryst. 26 283-291.
38. Letourneur, F , and R. D. Klausner 1992. Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3∈ Science (Wash. DC) 255:79-82.
39. Levins, B., and C. A Colaco. 1992. The CD3 γ-chain, transmembrane signalling or recognition? Immunogenetics. 35:140-143.
40. Malissen, B., and A. Schmitt-Verhulst. 1993. Transmembrane signalling through the T-cell-receptor-CD3 complex. Curr Opin. Immunol. 5.324-333.
41. Manolios, N., J. S. Bonifacino, and R. D. Klausner. 1990. Transmembrane helical interactions and the assembly of the T cell receptor complex. Science (Wash. DC). 249:274-277.
42. Manolios, N., F. Letourneur, J. S. Bonifacino, and R. D. Klausner. 1991. Pairwise, cooperative and inhibitory interactions describe the assembly and probable structure of the T-cell antigen receptor. EMBO (Eur. Mol Biol Organ.) J 10:1643-1651
43. Manolios, N., O. Kemp, and Z. G. Li. 1994. The T cell antigen receptor α and β chains interact via distinct regions with CD3 chains. Eur. J. Immunol. 24:84-92.
44. Marquart, M., J. Deisenhofer, R Huber, and W. Palm. 1980. Crystallographic refinement and atomic models of the intact immunoglobulin molecule KOL and its antigen binding fragment at 3.0Å and 1.9Å resolution. J. Mol Biol. 141:369-391.
45. Ohashi, P S., T. W. Mak, P. Van den Elsen, Y. Yanagi, Y. Yoshikai, A. F. Calman, C. Terhorst, J. D. Stobo, and A. Weiss. 1985. Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer. Nature (Lond). 316:606-609.
46. Padovan, E , G Casorati, P. Dellabona, S. Meyer, M. Brockhaus, and A. Lanzavecchia. 1993. Expression of two T cell receptor α chains: dual receptor T cells. Science (Wash. DC). 262:422-424.
47. Punt, J. A., J. L. Roberts, K. P. Kearse, and A. Singer 1994. Stoichiometry of the T cell antigen receptor (TCR) complex, each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chains. J. Exp. Med. 180:587-593.
48. Ryu, S. E., P. D. Kwong, A. Truneh, T G. Porter, J. Arthos, M. Rosenberg, X. P. Dai, N. H. Xuong, R. Axel, R. W. Sweet et al 1990. Crystal structure of an HIV-binding recombinant fragment of human CD4. Nature (Lond.) 348:419-426.
49. Saito, T., A. Weiss, J. Miller, M A. Norcross, and R. N Germain. 1987. Specific antigen-Ia activation of transfected human T cells expressing murine Ti αβ-human T3 receptor complexes. Nature (Lond.). 325.125-130.
50. Singer, S. J. 1990. The structure and insertion of integral proteins in membranes. Annu. Rev. Cell. Biol. 6:247-296.
51. Transy, C., P. Moingeon, C. Stebbins, and E. L. Reinherz. 1989. Deletion of the cytoplasmic region of the CD3 epsilon subunit does not prevent assembly of a functional T-cell receptor. Proc. Natl. Acad. Sci USA. 86: 7108-7112.
52. Van Neerven, J., J. E. Coligan, and F. Koning. 1990. Structural comparison of α/β and γ/δ T cell receptor-CD3 complexes reveals identical subunit interactions but distinct cross-linking patterns of T cell receptor chains. Eur. J Immunol. 20:2105-2111.
53. Varki, A. 1993 Biological roles of oligosaccharides: all the theories are correct. Glycobiology. 3:97-130.
54. Venkatachalam, C M., and G. N. Ramachandran. 1969. Conformation of polypeptide chains. Annu. Rev. Biochem. 38:45-82
55. Wang, J. H., Y. W. Yan, T. P. Garrett, J. H. Liu, D. W. Rodgers, R. L. Garlick, G. E. Tarr, Y. Husain, E. L. Reinherz, and S. C. Harrison. 1990. Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains. Nature (Lond.). 348:411-418.
56. Wange, R. L., S. N. Malek, S. Desiderio, and L. E. Samelson. 1993 Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor ζ and CD3 ∈ from activated Jurkat T cells. J. Biol. Chem. 268:19797-19801.
57. Wegener, A.-M. K., F Letourneur, A. Hoeveler, T. Brocker, F. Luton, and B. Malissen. 1992. The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell 68:83-95.
58. Wegener, A.-M. K , X. Hou, J. Dietrich, and C. Geisler. 1995. Distinct domains of the CD3-γ chain are involved in the surface expression and function of the T cell antigen receptor. J. Biol. Chem. 270:4675-4680
59. Wileman, T., L. P. Kane, J. Young, G. R. Carson, and C. Terhorst 1993. Associations between subunit ectodomains promote T cell antigen receptor assembly and protect against degradation in the ER. J. Cell Biol 122: 67-78.
60. Williams, A. F., and N. Barclay. 1988. The Immunoglobulin superfamily. Annu. Rev. Biol. 6:381-405.
61. Williams, A. M., and C. A. Enns. 1993. A region of the C-terminal portion of the human transferrin receptor contains an asparagine-linked glycosylation site critical for receptor structure and function. J. Biol. Chem. 268: 12780-12786.