Time course of response to ozone exposure in healthy adult females

Inhalation Toxicology

Volumn 12, Issue 3, 2000, Pages 151-167

  Folinsbee, Lawrence J ^a   Hazucha, Milan J ^b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034023382     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.1080/089583700196211     Document Type: Article

References (38)

1. Altose, M. D., Kelsen, S. G., Stanley, N. N., Levinson, R. S., Cherniack, N. S., and Fishman, A. P. 1976. Effects of hypercapnia on mouth pressure during airway occlusion in conscious man. J. Appl. Physiol. 40:338-344.
2. 3. J. Appl. Physiol. 64:605-610.
3. Bedi, J. F., Drechsler-Parks, D. M., and Horvath, S. M. 1985. Duration of increased pulmonary function sensitivity to an initial ozone exposure. Am. Ind. Hyg. Assoc. J. 46:731-734.
4. Bhalla, D. K., Mannix, R. C., Kleinman, M. T., and Crocker, T. T. 1986. Relative permeability of nasal, tracheal, and bronchoalveolar mucosa to macromolecules in rats exposed to ozone. J. Toxicol. Environ. Health 17:269-283.
5. Citterio, G., and Agostoni, E. 1983. Inspiratory facilitation and inhibition from pulmonary stretch receptors in rabbits. Respir. Physiol. 53:307-323.
6. Coleridge, J. C. G., Coleridge, H. M., Schelegle, E. S., and Green, J. F. 1993. Acute inhalation of ozone stimulates bronchial C-fibers and rapidly adapting receptors in dogs. J. Appl. Physiol. 74:2345-2352.
7. Folinsbee, L. J., and Hazucha, M. J. 1989. Persistence of ozone-induced changes in lung function and airway responsiveness. In Atmospheric ozone research and its policy implications: Proceedings of the 3rd US-Dutch International Symposium, eds. T. Schneider, S. D. Lee, G. J. R. Wolters, and L. D. Grant, vol. 35, pp. 483-492. Amsterdam: Elsevier.
8. Folinsbee, L. J., and Horvath, S. M. 1986. Persistence of the acute effects of ozone exposure. Aviat. Space Environ. Med. 57:1136-1143.
9. Folinsbee, L. J., Drinkwater, B. L., Bedi, J. F., and Horvath, S. M. 1978. The influence of exercise on the pulmonary function changes due to exposure to low concentrations of ozone. In Environmental stress: Individual human adaptations, eds. L. J. Folinsbee, J. A. Wagner, J. F. Borgia, B. L. Drinkwater, J. A. Gliner, and J. F. Bedi, pp. 125-145. New York: Academic Press.
10. Folinsbee, L. J., McDonnell, W. F., and Horstman, D. H. 1988. Pulmonary function and symptom responses after 6.6-hour exposure to 0.12 ppm ozone with moderate exercise. J. Air Pollut. Control Assoc. 38:28-35.
11. Folinsbee, L. J., Devlin, R. B., Abdul-Salaam, S., and Koren, H. S. 1993. Repeated severe ozone exposure causes depressed baseline spirometry. Am. Rev. Respir. Dis. 147:A638.
12. Folinsbee, L. J., Horstman, D. H., Kehrl, H. R., Harder, S., Abdul-Salaam, S., and Ives, P. J. 1994. Respiratory responses to repeated prolonged exposure to 0.12 ppm ozone. Am. J. Respir. Crit. Care Med. 149:98-105.
13. Gibbons, S. I., and Adams, W. C. 1984. Combined effects of ozone exposure and ambient heat on exercising females. J. Appl. Physiol. Respir. Environ. Exercise Physiol. 57:450-456.
14. Glover, D. E., Berntsen, J. H., Crider, W. L., and Strong, A. A. 1981. Design and performance of a system to control concentrations of common gaseous air pollutants within environmental laboratories used for human exposure studies. J. Environ. Sci. Health 16:501-522.
15. 2 on control of breathing in anesthetized cats. J. Appl. Physiol. Respir. Environ. Exercise Physiol. 43:844-851.
16. Haywood, C., and Bloete, M. E. 1969. Respiratory responses of healthy young women to carbon dioxide inhalation. J. Appl. Physiol. 27:32-35.
17. Hazucha, M. J., and Sant'Ambrogio, G. 1993. Effects of ozone on the activity of slowly (SAR) and rapidly adapting (RAR) receptors in cats. FASEB J. 7:407A.
18. Hazucha, M. J., Bates, D. V., and Bromberg, P. A. 1989. Mechanism of action of ozone on the human lung. J. Appl. Physiol. 67:1535-1541.
19. Hazucha, M. J., Madden, M., Pape, G., Becker, S., Devlin, R., Koren, H. S., Kehrl, H., and Bromberg, P. A. 1996. Effects of cyclo-oxygenase inhibition on ozone-induced respiratory inflammation and lung function changes. Eur. J. Appl. Physiol. Occup. Med. 73:17-27.
20. Holbrook, M., Gozzard, N., James, T., Higgs, G., and Hughes, B. 1996. Inhibition of bronchospasm and ozone-induced airway hyperresponsiveness in the guinea-pig by CDP840, a novel phosphodiesterase type 4 inhibitor. Br. J. Pharmacol. 118:1192-1200.
21. Horvath, S. M., Gliner, J. A., and Folinsbee, L. J. 1981. Adaptation to ozone: Duration of effect. Am. Rev. Respir. Dis. 123:496-499.
22. Igarashi, A., Iijima, H., Tamura, G., and Shirato, K. 1998. Tazanolast inhibits ozone-induced airway hyperresponsiveness in guinea pigs. Am. J. Respir. Crit. Care Med. 157:1531-1535.
23. Kehrl, H. R., Vincent, L. M., Kowalsky, R. J., Horstman, D. H., O'Neil, J. J., McCartney, W. H., and Bromberg, P. A. 1987. Ozone exposure increases respiratory epithelial permeability in humans. Am. Rev. Respir. Dis. 135:1124-1128.
24. Koren, H. S., Devlin, R. B., Graham, D. E., Mann, R., McGee, M. P., Horstman, D. H., Kozumbo, W. J., Becker, S., House, D. E., McDonnell, W. F., and Bromberg, P. A. 1989. Ozone-induced inflammation in the lower airways of human subjects. Am. Rev. Respir. Dis. 139:407-415.
25. Matthews, A. W., and Howell, J. B. L. 1975. The rate of isometric inspiratory pressure development as a measure of responsiveness to carbon dioxide in man. Clin. Sci. Mol. Med. 49:57-68.
26. McDonnell, W. F., Horstman, D. H., Hazucha, M. J., Seal, E., Jr., Haak, E. D., Salaam, S. A., and House, D. E. 1983. Pulmonary effects of ozone exposure during exercise: Dose-response characteristics. J. Appl. Physiol. Respir. Environ. Exercise Physiol. 54:1345-1352.
27. Messineo, T. D., and Adams, W. C. 1990. Ozone inhalation effects in females varying widely in lung size: Comparison with males. J. Appl. Physiol. 69:96-103.
28. Morrison, D. F. 1967. Multivariate statistical methods. New York: McCraw-Hill.
29. Murlas, C. G., and Roum, J. H. 1985. Sequence of pathologic changes in the airway mucosa of guinea pigs during ozone-induced bronchial hyperreactivity. Am. Rev. Respir. Dis. 131:314-320.
30. Passannante, A. N., Hazucha, M. J., Bromberg, P. A., Seal, E., Folinsbee, L., and Koch, G. 1998. Nociceptive mechanisms modulate ozone-induced human lung function decrements. J. Appl. Physiol. 85:1863-1870.
31. 2 by rebreathing. Chest 70:118S-121S.
32. Schelegle, E. S., Carl, M. L., Coleridge, H. M., Coleridge, J. C. G., and Green, J. F. 1993. Contribution of vagal afferents to respiratory reflexes evoked by acute inhalation of ozone in dogs. J. Appl. Physiol. 74:2338-2344.
33. Seal, E., Jr., McDonnell, W. F., House, D. E., Salaam, S. A., Dewitt, P. J., Butler, S. O., Green, J., and Raggio, L. 1993. The pulmonary response of white and black adults to six concentrations of ozone. Am. Rev. Respir. Dis. 147:804-810.
34. Tepper, J. S., Costa, D. E., Lehmann, J. R., Weber, M. F., and Hatch, G. E. 1989. Unattenuated structural and biochemical alterations in the rat lung during functional adaptation to ozone. Am. Rev. Respir. Dis. 140:493-501.
35. Tepper, J. S., Wiester, M. J., Weber, M. F., and Menache, M. G. 1990. Measurements of cardiopulmonary response in awake rats during acute exposure to near-ambient concentrations of ozone. Fundam. Appl. Toxicol. 10:7-15.
36. Ward, S. A., Aqleh, K. A., and Poon, C.-S. 1981. Breath-to-breath monitoring of inspiratory occlusion pressure in humans. J. Appl. Physiol. 51:520-523.
37. Weinmann, G. G., Weidenbach-Gerbase, M., Foster, W. M., Zacur, H., and Frank, R. 1995. Evidence for ozone-induced small-airway dysfunction: Lack of menstrual-cycle and gender effects. Am. J. Respir. Crit. Care Med. 152:988-996.
38. Whitelaw, W. A., Derenne, J. P., and Milic-Emili, J. 1975. Occlusion pressure as a measure of respiratory center output in conscious man. Respir. Physiol. 23:181-199.