Clinical experience with thalidomide in multiple myeloma: Phase II trial results in refractory disease and ongoing studies

Seminars in Hematology

Volumn 37, Issue 1 SUPPL. 3, 2000, Pages 15-21

  Munshi, Nikhil C ^a   Desikan, K R ^a   Barlogie, Bart ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THALIDOMIDE;

ADULT; ADVANCED CANCER; ANGIOGENESIS; ARTICLE; CANCER RECURRENCE; CANCER SURVIVAL; CASE REPORT; CLINICAL TRIAL; DRUG EFFICACY; DRUG INDUCED DISEASE; DRUG TOLERABILITY; HUMAN; MALE; MULTIPLE MYELOMA; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROGNOSIS;

EID: 0034019973     PISSN: 00371963     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0037-1963(00)90078-7     Document Type: Article

References (15)

1. KR Desikan MV Dhodapkar NC Munshi Recent advances in the treatment of multiple myeloma Curr Opin Hematol 6 1999 216 221
2. Cancer Facts & Figures—1999 1999 American Cancer Society Atlanta, GA 1 36
3. R Bataille J-L Harousseau Multiple myeloma N Engl J Med 336 1997 1657 1664
4. KC Anderson TJ Hamblin A Traynor Management of multiple myeloma today Semin Hematol 36 1999 3 8 (suppl 3)
5. Y-W Huang A Hamilton OJ Arnuk Current drug therapy for multiple myeloma Drugs 57 1999 485 506
6. B Barlogie S Jagannath KR Desikan Total therapy with tandem transplants for newly diagnosed multiple myeloma Blood 93 1999 55 65
7. B Barlogie S Jagannath DH Vesole Superiority of tandem autologous transplantation over standard therapy for previously untreated multiple myeloma Blood 89 1997 789 793
8. B Barlogie R Desikan D Spoon Tandem transplants (TAT) in over 1,000 patients with multiple myeloma (MM)—Inferior prognosis with chromosome 13 deletion Proc Am Soc Clin Oncol 18 1999 5a (abstr)
9. J Folkman Angiogenesis in cancer, vascular, rheumatoid and other diseases Nature Med 1 1995 27 31
10. AR Perez-Atayde SE Sallan U Tedrow Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia Am J Pathol 150 1997 815 821
11. N Munshi CS Wilson J Penn Angiogenesis in newly diagnosed multiple myeloma: Poor prognosis with increased microvessel density (MVD) in bone marrow biopsies Blood 92 suppl 1 1998 98a abstr
12. RJ D'Amato MS Loughnan E Flynn Thalidomide is an inhibitor of angiogenesis Proc Natl Acad Sci USA 91 1994 4082 4085
13. S Singhal J Mehta R Desikan Antitumor activity of thalidomide in refractory multiple myeloma N Engl J Med 341 1999 1565 1571
14. M Nguyen C Tran S Barsky Thalidomide and chemotherapy combination: Preliminary results of preclinical and clinical studies Int J Oncol 10 1997 965 969
15. Barlogie B, Desikan R, Munshi N, et al: Single course D.T. PACE anti-angiochemotherapy effects CR in plasma cell leukemia and fulminant multiple myeloma (MM). Blood 92: 273b (suppl 1, abstr)