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Volumn 20, Issue 5, 2000, Pages 1309-1315

In vivo metabolism of ApoB, ApoA-I, and VLDL triglycerides in a form of hypobetalipoproteinemia not linked to the ApoB gene

Author keywords

Apolipoprotein A I; Apolipoprotein B; Familial hypobetalipoproteinemia; Stable isotopes; Triglycerides

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; CHOLESTEROL; DEUTERIUM; GLYCEROL; LEUCINE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

EID: 0034019727     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.20.5.1309     Document Type: Article
Times cited : (32)

References (40)
  • 1
    • 0001903995 scopus 로고
    • Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins
    • Scriver CR, Beaudet AL, Sly WS, Valle D, eds. New York, NY: McGraw-Hill Book Co
    • Kane JP, Havel RJ, Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The Metabolic Bases of Inherited Disease. 7th ed. New York, NY: McGraw-Hill Book Co; 1995:1853-1885.
    • (1995) The Metabolic Bases of Inherited Disease. 7th Ed. , pp. 1853-1885
    • Kane, J.P.1    Havel, R.J.2
  • 5
    • 0032898617 scopus 로고    scopus 로고
    • Known mutations of apob account for only a small minority of hypobetalipoproteinemia
    • Wu J, Kim J, Li Q, Kwok P, Cole T, Cefalu B, Averna M, Schonfeld G. Known mutations of apoB account for only a small minority of hypobetalipoproteinemia. J Lipid Res. 1999;40:955-959.
    • (1999) J Lipid Res , vol.40 , pp. 955-959
    • Wu, J.1    Kim, J.2    Li, Q.3    Kwok, P.4    Cole, T.5    Cefalu, B.6    Averna, M.7    Schonfeld, G.8
  • 6
    • 0031771856 scopus 로고    scopus 로고
    • Frequency of apoB and apoE gene mutations as causes of hypobetalipoproteinemia in the framingham offspring population
    • Welty FK, Lahoz C, Tucker KL, Ordovas JM, Wilson PW, Schaefer EJ. Frequency of apoB and apoE gene mutations as causes of hypobetalipoproteinemia in the Framingham offspring population. Arterioscler Thromb Vasc Biol. 1998;18:1745-1751.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1745-1751
    • Welty, F.K.1    Lahoz, C.2    Tucker, K.L.3    Ordovas, J.M.4    Wilson, P.W.5    Schaefer, E.J.6
  • 7
    • 0029096553 scopus 로고
    • The hypobetalipoproteinemias
    • Schonfeld G. The hypobetalipoproteinemias. Annu Rev Nutr. 1995;15: 23-34.
    • (1995) Annu Rev Nutr , vol.15 , pp. 23-34
    • Schonfeld, G.1
  • 9
    • 0029971275 scopus 로고    scopus 로고
    • Positive linear correlation between the length of truncated apolipoprotein B and its secretion rate (in vivo studies in apoB-89, apoB-75, apoB-54.8, and apoB 31 heterozygotes)
    • Parhofer KG, Barrett PHR, Bier DM, Schonfeld G. Positive linear correlation between the length of truncated apolipoprotein B and its secretion rate (in vivo studies in apoB-89, apoB-75, apoB-54.8, and apoB 31 heterozygotes). J Lipid Res. 1996;37:844-852.
    • (1996) J Lipid Res , vol.37 , pp. 844-852
    • Parhofer, K.G.1    Barrett, P.H.R.2    Bier, D.M.3    Schonfeld, G.4
  • 10
    • 0026749611 scopus 로고
    • Lipoproteins containing the truncated apolipoprotein, apoB-89, are cleared from human plasma more rapidly than apoB-100 containing lipoproteins in vivo
    • Parhofer KG, Barrett PHR, Bier DM, Schonfeld G. Lipoproteins containing the truncated apolipoprotein, apoB-89, are cleared from human plasma more rapidly than apoB-100 containing lipoproteins in vivo. J Clin Invest. 1992;89:1931-1937.
    • (1992) J Clin Invest , vol.89 , pp. 1931-1937
    • Parhofer, K.G.1    Barrett, P.H.R.2    Bier, D.M.3    Schonfeld, G.4
  • 11
    • 0026697215 scopus 로고
    • ApoB-75, a truncation of apolipoprotein B associated with familial hypobetalipoproteinemia: Genetic and kinetic studies
    • Krul ES, Parhofer KG, Barrett PHR, Wagner RD, Schonfeld G. ApoB-75, a truncation of apolipoprotein B associated with familial hypobetalipoproteinemia: genetic and kinetic studies. J Lipid Res. 1992;33:1037-1050.
    • (1992) J Lipid Res , vol.33 , pp. 1037-1050
    • Krul, E.S.1    Parhofer, K.G.2    Barrett, P.H.R.3    Wagner, R.D.4    Schonfeld, G.5
  • 14
    • 0032568129 scopus 로고    scopus 로고
    • Genetic heterogeneity in familial hypobetalipoproteinemia: Linkage and non-linkage to the apoB gene in caucasian families
    • Pulai JI, Neuman RJ, Groenewegen AW, Wu J, Schonfeld G. Genetic heterogeneity in familial hypobetalipoproteinemia: linkage and non-linkage to the apoB gene in Caucasian families. Am J Med Genet. 1998;76:79-86.
    • (1998) Am J Med Genet , vol.76 , pp. 79-86
    • Pulai, J.I.1    Neuman, R.J.2    Groenewegen, A.W.3    Wu, J.4    Schonfeld, G.5
  • 16
    • 0002349279 scopus 로고
    • An improved method of separation of triglyceride-rich lipoproteins by FPLC
    • Cole TG, Kitchens RT, Daugherty A, Schonfeld G. An improved method of separation of triglyceride-rich lipoproteins by FPLC. Pharm Biocommun. 1988;4:4-6.
    • (1988) Pharm Biocommun , vol.4 , pp. 4-6
    • Cole, T.G.1    Kitchens, R.T.2    Daugherty, A.3    Schonfeld, G.4
  • 17
    • 0022556137 scopus 로고
    • Nondenaturing polyacrylamide gradient gel electrophoresis
    • Nichols AV, Krauss RM, Musliner TA. Nondenaturing polyacrylamide gradient gel electrophoresis. Methods Enzymol. 1983;128:417-431.
    • (1983) Methods Enzymol , vol.128 , pp. 417-431
    • Nichols, A.V.1    Krauss, R.M.2    Musliner, T.A.3
  • 18
    • 0025739878 scopus 로고
    • Determination of kinetic parameters of apolipoprotein-B metabolism using amino-acids labeled with stable isotopes
    • Parhofer KG, Barrett PH, Bier DM, Schonfeld G. Determination of kinetic parameters of apolipoprotein-B metabolism using amino-acids labeled with stable isotopes. J Lipid Res. 1991;32:1311-1323.
    • (1991) J Lipid Res , vol.32 , pp. 1311-1323
    • Parhofer, K.G.1    Barrett, P.H.2    Bier, D.M.3    Schonfeld, G.4
  • 20
    • 0016391907 scopus 로고
    • Determination of amino acid profiles in biological samples by gas chromatography
    • Adams RF. Determination of amino acid profiles in biological samples by gas chromatography. J Chromatogr. 1974;95:189-212.
    • (1974) J Chromatogr , vol.95 , pp. 189-212
    • Adams, R.F.1
  • 21
    • 0021672477 scopus 로고
    • Direct determination of human and rabbit apolipoprotein B selectively precipitated with butanol-isopropyl ether
    • Klein RL, Zilversmit DB. Direct determination of human and rabbit apolipoprotein B selectively precipitated with butanol-isopropyl ether. J Lipid Res. 1984;25:1380-1386.
    • (1984) J Lipid Res , vol.25 , pp. 1380-1386
    • Klein, R.L.1    Zilversmit, D.B.2
  • 22
    • 0025913070 scopus 로고
    • Incorporation of a stable isotopically labeled amino acid into multiple human apolipoproteins
    • Patterson BW, Hachey DL, Cook GL, Amann JM, Klein PD. Incorporation of a stable isotopically labeled amino acid into multiple human apolipoproteins. J Lipid Res. 1991;32:1063-1072.
    • (1991) J Lipid Res , vol.32 , pp. 1063-1072
    • Patterson, B.W.1    Hachey, D.L.2    Cook, G.L.3    Amann, J.M.4    Klein, P.D.5
  • 23
    • 0032693382 scopus 로고    scopus 로고
    • Validation of a new procedure to determine plasma fatty acid concentration and isotopic enrichment
    • Patterson BW, Zhao G, Elias N., Hachey DL, Klein S. Validation of a new procedure to determine plasma fatty acid concentration and isotopic enrichment. J Lipid Res. 1999;40:2118-2124.
    • (1999) J Lipid Res , vol.40 , pp. 2118-2124
    • Patterson, B.W.1    Zhao, G.2    Elias, N.3    Hachey, D.L.4    Klein, S.5
  • 25
    • 0032698343 scopus 로고    scopus 로고
    • Decreased production rates of VLDL triglycerides and apolipoprotein B 100 in subjects heterozygotes for familial hypobetalipoproteinemia
    • Elias N, Patterson BW, Schonfeld G. Decreased production rates of VLDL triglycerides and apolipoprotein B 100 in subjects heterozygotes for familial hypobetalipoproteinemia. Arterioscler Thromb Vasc Biol. 1999;19:2714-2721.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2714-2721
    • Elias, N.1    Patterson, B.W.2    Schonfeld, G.3
  • 26
    • 0018418362 scopus 로고
    • Kinetic model for production and metabolism of very low density lipoprotein triglycerides: Evidence for a slow production pathway and results for normolipidemic subjects
    • Zech LA, Grundy SM, Steinberg D, Berman M. Kinetic model for production and metabolism of very low density lipoprotein triglycerides: evidence for a slow production pathway and results for normolipidemic subjects. J Clin Invest. 1979;63:1262-1273.
    • (1979) J Clin Invest , vol.63 , pp. 1262-1273
    • Zech, L.A.1    Grundy, S.M.2    Steinberg, D.3    Berman, M.4
  • 27
    • 0029585391 scopus 로고    scopus 로고
    • Identification and characterization of truncated forms of apolipoprotein B in hypobetalipoproteinemia
    • Young SG, Krul ES, McCormick S, Farese RV Jr, Linton MF. Identification and characterization of truncated forms of apolipoprotein B in hypobetalipoproteinemia. Methods Enzymol. 1996;263:120-145.
    • (1996) Methods Enzymol , vol.263 , pp. 120-145
    • Young, S.G.1    Krul, E.S.2    McCormick, S.3    Farese R.V., Jr.4    Linton, M.F.5
  • 28
    • 0018886617 scopus 로고
    • Kinetic basis of the primary hyperlipidemias: Studies of apolipoprotein B turnover in genetically defined subjects
    • Janus ED, Nicoll AM, Turner PR, Magill P, Lewis B. Kinetic basis of the primary hyperlipidemias: studies of apolipoprotein B turnover in genetically defined subjects. Eur J Clin Invest. 1980;10:161-172.
    • (1980) Eur J Clin Invest , vol.10 , pp. 161-172
    • Janus, E.D.1    Nicoll, A.M.2    Turner, P.R.3    Magill, P.4    Lewis, B.5
  • 30
    • 0029033102 scopus 로고
    • Synthesis and secretion of apolipoprotein B from cultured liver cells
    • Ginsberg HN. Synthesis and secretion of apolipoprotein B from cultured liver cells. Curr Opin Lipidol. 1995;6:275-280.
    • (1995) Curr Opin Lipidol , vol.6 , pp. 275-280
    • Ginsberg, H.N.1
  • 31
    • 0029795221 scopus 로고    scopus 로고
    • ApoB-100 secretion by HepG2 cells is regulated by the rate of triglyceride biosynthesis but not by intracellular lipid pools
    • Benoist F, Grand-Perret T. ApoB-100 secretion by HepG2 cells is regulated by the rate of triglyceride biosynthesis but not by intracellular lipid pools. Arterioscler Thromb Vasc Biol. 1996;16:1229-1235.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1229-1235
    • Benoist, F.1    Grand-Perret, T.2
  • 32
    • 0025667289 scopus 로고
    • Regulation of apoB secretion from HepG2 cells: Evidence for a critical role for cholesteryl ester synthesis in the response to a fatty acid challenge
    • Cianflone KM, Yasruel Z, Rodriguez MA, Vas D, Sniderman AD. Regulation of apoB secretion from HepG2 cells: evidence for a critical role for cholesteryl ester synthesis in the response to a fatty acid challenge. J Lipid Res. 1990;31:2045-2055.
    • (1990) J Lipid Res , vol.31 , pp. 2045-2055
    • Cianflone, K.M.1    Yasruel, Z.2    Rodriguez, M.A.3    Vas, D.4    Sniderman, A.D.5
  • 34
    • 0027504998 scopus 로고
    • Proteolysis and lipid facilitated translocation are distinct but competitive processes which regulate secretion of apolipoprotein B in HepG2 cells
    • Sakata N, Wu X, Dixon JL, Ginsberg HN. Proteolysis and lipid facilitated translocation are distinct but competitive processes which regulate secretion of apolipoprotein B in HepG2 cells. J Biol Chem. 1993;268: 22967-22970.
    • (1993) J Biol Chem , vol.268 , pp. 22967-22970
    • Sakata, N.1    Wu, X.2    Dixon, J.L.3    Ginsberg, H.N.4
  • 35
    • 0017239547 scopus 로고
    • Receptor-mediated control of cholesterol metabolism
    • Brown MS, Goldstein JL. Receptor-mediated control of cholesterol metabolism. Science. 1976;191:151-1554.
    • (1976) Science , vol.191 , pp. 151-1554
    • Brown, M.S.1    Goldstein, J.L.2
  • 36
    • 0002843643 scopus 로고    scopus 로고
    • Effect of apheresis on kinetic parameters of apoprotein B metabolism in familial hypercholesterolemia
    • Parhofer KG, Barrett PHR, Demant T, Richter WO, Schwandt P. Effect of apheresis on kinetic parameters of apoprotein B metabolism in familial hypercholesterolemia. Circulation. 1996;94:1-583.
    • (1996) Circulation , vol.94 , pp. 1-583
    • Parhofer, K.G.1    Barrett, P.H.R.2    Demant, T.3    Richter, W.O.4    Schwandt, P.5
  • 37
    • 0026073753 scopus 로고
    • Increased apoA-I and apoA-II fractional catabolic rates in patients with low high density lipoproteincholesterol levels with or without hypertriglyceridemia
    • Brinton EA, Eisenberg S, Breslow JL. Increased apoA-I and apoA-II fractional catabolic rates in patients with low high density lipoproteincholesterol levels with or without hypertriglyceridemia. J Clin Invest. 1991;87:536-544.
    • (1991) J Clin Invest , vol.87 , pp. 536-544
    • Brinton, E.A.1    Eisenberg, S.2    Breslow, J.L.3
  • 39
    • 0028175551 scopus 로고
    • Human HDL cholesterol levels are determined by apoA-I fractional catabolic rate, which correlates inversely with estimates of HDL particle size: Effects of gender, hepatic and lipoprotein lipases, triglyceride and insulin levels, and body fat distribution
    • Brinton EA, Eisenberg S, Breslow JL. Human HDL cholesterol levels are determined by apoA-I fractional catabolic rate, which correlates inversely with estimates of HDL particle size: effects of gender, hepatic and lipoprotein lipases, triglyceride and insulin levels, and body fat distribution. Arterioscler Thromb Vasc Biol. 1994;14:707-720.
    • (1994) Arterioscler Thromb Vasc Biol , vol.14 , pp. 707-720
    • Brinton, E.A.1    Eisenberg, S.2    Breslow, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.