Identification of a high frequency of chromosomal rearrangements in the centromeric regions of prostate cancer cell lines by sequential Giemsa banding and spectral karyotyping

Molecular Diagnosis

Volumn 5, Issue 1, 2000, Pages 23-32

  Squire, Jeremy ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Centromere; Cytogenetics; Fluorescence in situ hybridization; Translocation breakpoint

Indexed keywords

ARTICLE; CARCINOGENESIS; CENTROMERE; CHROMOSOME 11; CHROMOSOME 12; CHROMOSOME 14; CHROMOSOME 15; CHROMOSOME 4; CHROMOSOME 5; CHROMOSOME 6; CHROMOSOME 8; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; KARYOTYPING; PROSTATE CANCER;

EID: 0034018649     PISSN: 10848592     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1084-8592(00)00007-2     Document Type: Article

References (5)

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2. Weinberg R: How cancer arises. Sci Am 1996;275: 62-70
3. Rowley JD: The critical role of chromosome translocations in human leukemias. Annu Rev Genet 1998:32:495-519
4. Ladanyi M: The emerging molecular genetics of sarcoma translocations. Diagn Mol Pathol 1995;4:162-173
5. Webb HD, Hawkins AL, Griffin CA: Cytogenetic abnormalities are frequent in uncultured prostate cancer cells. Cancer Genet Cytogenet 1996;88:126-132