메뉴 건너뛰기




Volumn 85, Issue 3, 2000, Pages 113-121

Molecular modelling and drug design

Author keywords

Computer graphics; Haptic device; Molecular modelling; Molecular sculptures; Structure based drug design

Indexed keywords

METALLOPROTEINASE; PROTEINASE INHIBITOR;

EID: 0034017903     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(99)00069-8     Document Type: Review
Times cited : (17)

References (33)
  • 1
    • 16044375105 scopus 로고
    • Crystal structures of HIV-1 protease-inhibitor complexes
    • Appelt K. Crystal structures of HIV-1 protease-inhibitor complexes. Perspec Drug Discov Des. 1:1993;23-48.
    • (1993) Perspec Drug Discov des , vol.1 , pp. 23-48
    • Appelt, K.1
  • 5
    • 0024431034 scopus 로고
    • The refined 1.9 angstroms crystal structure of human alpha-thrombin: Interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment
    • Bode W., Mayr I., Baumann U., Huber R., Stone S.R., Hofsteenge J. The refined 1.9 angstroms crystal structure of human alpha-thrombin. interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment EMBO J. 8:1989;3467-3475.
    • (1989) EMBO J , vol.8 , pp. 3467-3475
    • Bode, W.1    Mayr, I.2    Baumann, U.3    Huber, R.4    Stone, S.R.5    Hofsteenge, J.6
  • 6
    • 0029866390 scopus 로고    scopus 로고
    • Batimastat, a potent matrix metalloproteinase inhibitor, exhibits an unexpected mode of binding
    • Botos I., Scapozza L., Zhang D., Liotta L.A., Meyer E.F. Batimastat, a potent matrix metalloproteinase inhibitor, exhibits an unexpected mode of binding. Proc Natl Acad Sci USA. 93:1996;2749-2754.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2749-2754
    • Botos, I.1    Scapozza, L.2    Zhang, D.3    Liotta, L.A.4    Meyer, E.F.5
  • 9
    • 0001289724 scopus 로고
    • Einflus der Configuration auf die Wirkung der Enzyme
    • Fischer E. Einflus der Configuration auf die Wirkung der Enzyme. Ber Deutschen Chem Gesellschaft. 27:1894;2984-2993.
    • (1894) Ber Deutschen Chem Gesellschaft , vol.27 , pp. 2984-2993
    • Fischer, E.1
  • 11
    • 0039122255 scopus 로고    scopus 로고
    • Structure of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor α convertase inhibitors
    • Gomis-Rüth F.-X., Meyer E.F., Kress L.F., Politi V. Structure of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor α convertase inhibitors. Protein Sci. 7:1998;283-292.
    • (1998) Protein Sci , vol.7 , pp. 283-292
    • Gomis-Rüth, F.-X.1    Meyer, E.F.2    Kress, L.F.3    Politi, V.4
  • 13
    • 0343616242 scopus 로고
    • On the combining power of atoms
    • Hofmann A.W. On the combining power of atoms. Proc R Inst. 4:1865;401-430.
    • (1865) Proc R Inst , vol.4 , pp. 401-430
    • Hofmann, A.W.1
  • 16
    • 0029042511 scopus 로고
    • Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 Å resolution
    • Lowe J., Stock D., Jap B., Zwickl P., Baumeister W., Huber R. Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 Å resolution. Science. 268:1995;533-539.
    • (1995) Science , vol.268 , pp. 533-539
    • Lowe, J.1    Stock, D.2    Jap, B.3    Zwickl, P.4    Baumeister, W.5    Huber, R.6
  • 17
    • 84977303841 scopus 로고
    • The geometry of the reactive site and of the peptide groups in trypsin, trypsinogen and its complexes with inhibitors
    • Marquart M., Walter J., Deisenhofer J., Bode W., Huber R. The geometry of the reactive site and of the peptide groups in trypsin, trypsinogen and its complexes with inhibitors. Acta Crystallogr. 39B:1983;480-490.
    • (1983) Acta Crystallogr , vol.39 , pp. 480-490
    • Marquart, M.1    Walter, J.2    Deisenhofer, J.3    Bode, W.4    Huber, R.5
  • 20
    • 85010149943 scopus 로고
    • Interactive graphics in medicinal chemistry
    • E.J. Ariens. New York: Academic Press
    • Meyer E.F. Interactive graphics in medicinal chemistry. Ariens E.J. Drug Design, Vol. IX. 1980;267-289 Academic Press, New York.
    • (1980) Drug Design, Vol. IX , pp. 267-289
    • Meyer, E.F.1
  • 21
    • 0027082924 scopus 로고
    • Internal water molecules and H-bonding in biological macromolecules: A review of structural features with functional implications
    • Meyer E.F. Internal water molecules and H-bonding in biological macromolecules. a review of structural features with functional implications Protein Sci. 1:1992;1543-1562.
    • (1992) Protein Sci , vol.1 , pp. 1543-1562
    • Meyer, E.F.1
  • 22
    • 0343616235 scopus 로고
    • Emil Fischer: Then and now
    • Meyer E.F. Emil Fischer. then and now Pharm Acta Helv. 69:1995;177-183.
    • (1995) Pharm Acta Helv , vol.69 , pp. 177-183
    • Meyer, E.F.1
  • 23
    • 0031182215 scopus 로고    scopus 로고
    • The first years of the Protein Data Bank
    • Meyer E.F. The first years of the Protein Data Bank. Protein Sci. 6:1997;1591-1597.
    • (1997) Protein Sci , vol.6 , pp. 1591-1597
    • Meyer, E.F.1
  • 24
  • 26
    • 0010967132 scopus 로고
    • Information retrieval, computer graphics and remote computing
    • F.R. Ahmed. Copenhagen: Munksgaard
    • Morimoto C.N., Meyer E.F. Information retrieval, computer graphics and remote computing. Ahmed F.R. Crystallographic Computing Techniques. 1976;488-496 Munksgaard, Copenhagen.
    • (1976) Crystallographic Computing Techniques , pp. 488-496
    • Morimoto, C.N.1    Meyer, E.F.2
  • 27
    • 24544467333 scopus 로고
    • Modern structural chemistry
    • Pauling L. Modern structural chemistry. Chem Eng News. 24:1946;1788.
    • (1946) Chem Eng News , vol.24 , pp. 1788
    • Pauling, L.1
  • 28
    • 0032530708 scopus 로고    scopus 로고
    • Structure of translation initiation factor 5a from Pyrobaculum aerophilum at 1.75 angstrom resolution
    • Peat T.S., Newman J., Waldo G.S., Berendzen J., Terwilliger T.C. Structure of translation initiation factor 5a from Pyrobaculum aerophilum at 1.75 angstrom resolution. Structure. 6:1998;1207-1214.
    • (1998) Structure , vol.6 , pp. 1207-1214
    • Peat, T.S.1    Newman, J.2    Waldo, G.S.3    Berendzen, J.4    Terwilliger, T.C.5
  • 29
    • 0028009093 scopus 로고
    • The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
    • Picot D., Loll P.J., Garavito R.M. The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature. 367:1994;243-249.
    • (1994) Nature , vol.367 , pp. 243-249
    • Picot, D.1    Loll, P.J.2    Garavito, R.M.3
  • 32


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.