Aldose reductase gene polymorphisms and susceptibility to diabetic nephropathy in Type 1 diabetes mellitus

Diabetic Medicine

Volumn 17, Issue 2, 2000, Pages 111-118

  Moczulski, D K ^a,b,c   Scott, L ^a,b   Antonellis, A ^a   Rogus, J J ^a,d   Rich, S S ^e   Warram, J H ^a   Krolewski, Andrzej S ^a,b  

^a JOSLIN DIABETES CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MEDICAL UNIVERSITY OF SILESIA   (Poland)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Aldose reductase gene; Diabetic nephropathy; Genetic susceptibility; Type 1 diabetes mellitus

Indexed keywords

ALDEHYDE REDUCTASE;

ADOLESCENT; ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DINUCLEOTIDE REPEAT; DNA FLANKING REGION; DNA POLYMORPHISM; DNA SEQUENCE; GENETIC LINKAGE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PROMOTER REGION;

EID: 0034015408     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-5491.2000.00225.x     Document Type: Article

References (32)

1. 1 Andersen AR, Christiansen JS, Andersen JK, Kreiner S, Deckert T. Diabetic nephropathy in type I (insulin-dependent) diabetes an epidemiologic study. Diabetologia 1983; 25: 496-501.
2. 2 Krolewski AS, Warram JH, Christlieb AR, Busick EJ, Kahn CR. The changing natural history of nephropathy in type I diabetes. Am J Med 1985; 78: 785-794.
3. 3 Krolewski AS, Warram JH, Rand LI, Kahn CR. Epidemiologic approach to the etiology of type I diabetes mellitus and its complications. N Engl J Med 1987; 317: 1390-1398.
4. 4 Seaquist ER, Goetz FC, Rich S, Barbosa J. Familial clustering of diabetic kidney diseases, evidence for genetic susceptibility to diabetic nephropathy. N Engl J Med 1989; 320: 1161-1165.
5. 5 Borch-Johnsen K, Norgaard K, Hommel E, Mathiesen ER, Jensen JS, Deckert T, Parving HH. Is diabetic nephropathy an inherited condition? Kidney Int 1992; 41: 719-722.
6. 6 Quinn M, Angelico MC, Warram JH, Krolewski AS. Familiar factors determine the development of diabetic nephropathy in patients with IDDM. Diabetologia 1996; 39: 940-945.
7. 7 The Diabetes Control and Complications Trial Research Group. Clustering of long-term complications in families with diabetes in the diabetes control and complications trial. Diabetes 1997; 46: 1829-1839.
8. 8 Kicic E, Warren-Perry M, Cull VS, Wise PH, Chung S, Palmer TN. Restriction fragment length polymorphisms of the human aldose reductase gene, a preliminary report. Diab Res Clin Pract 1993; 20: 165-168.
9. 9 Patel A, Hibberd ML, Millward BA, Demaine AG. Chromosome 7q35 and susceptibility to diabetic microvascular complications. J Diab Comp 1996; 10: 62-67.
10. 10 Patel A, Ratanachaiyavong S, Millward BA, Demaine AG. Polymorphism of aldose reductase locus (ALR 2) and susceptibility to diabetic microvascular complications. Adv Exp Mol Biol 1993; 328: 325-332.
11. 11 Heesom AE, Hibberd ML, Millward A, Demaine AG. Polymorphism in the 5′-end of the aldose reductase gene is strongly associated with the development of diabetic nephropathy in type I diabetes. Diabetes 1997; 46: 287-291.
12. 12 Greene DA, Lattimer SA, Sima AAF. Sorbitol, phosphoinositides and sodium-potassium-ATPase in the pathogenesis of diabetic complications. N Engl J Med 1987; 316: 599-606.
13. 13 Tilton RG, Chang K, Nyengaard JR, Van den Enden M, Ido Y, Williamson JR. Inhibition of sorbitol dehydrogenase. effects on vascular and neural dysfunction in steptozocin-induced diabetic rats. Diabetes 1995; 44: 234-242.
14. 14 Kador PF, Kinoshita JI. Role of aldose reductase in the development of diabetes-associated complications. Am J Med 1985; 79 (Suppl. 5a): 8-12.
15. 15 Shah VO, Dorin RI, Sun Y, Braun M, Zager PG. Aldose reductase gene expression is increased in diabetic nephropathy. J Clin Endocrinol Metab 1997; 82: 2294-2298.
16. 16 Graham A, Heath P, Morten JEN, Markham AF. The human aldose reductase gene maps to chromosome region 7q35. Hum Genet 1991; 86: 509-514.
17. 17 Schuler GD, Boguski MS, Stewart EA, Stein LD, Gyapay G, Rice K et al. A gene map of the human genome. Science 1996; 274: 540-546.
18. 18 Graham A, Brown L, Hedge PJ, Gammark AJ, Markham AF. Structure of the human aldose reductase gene. J Biol Chem 1991; 266: 6872-6877.
19. 19 Ko BCB, Lam KSL, Wat NMS, Chung SM. An (A-C) n dinucleotide repeat polymorphic marker at the 5′ end of the aldose reductase gene is associated with early-onset diabetic retinopathy in NIDDM. Diabetes 1995; 44: 727-732.
20. 20 Shah VO, Scavini M, Nikolic J, Sun Y, Vai S, Griffith JK et al. Z-2 microsatellite allele is linked to increased expression of the aldose reductase gene in diabetic nephropathy. J Clin Endocrinol Metab 1998; 83: 2886-2891.
21. 21 Kao Y-L, Donaghue K, Chan A, Knight J, Silink M. A novel polymorphism in the aldose reductase gene promote region is strongly associate with diabetic retinopathy in adolescents with type I diabetes. Diabetes 1999; 48: 1338-1340.
22. 22 Krolewski AS, Laffel L, Krolewski M, Quinn M, Warram JH. Glycosylated hemoglobin and risk of microalbuminuria in IDDM. N Engl J Med 1995; 332: 1251-1255.
23. 23 Dracopoli NC (Ed). Current Protocols in Human Genetics. Chichester: John Wiley & Sons, 1994.
24. 24 Terwilliger J, Ott J. Handbook for Human Genetic Linkage. Baltimore: Johns Hopkins University Press, 1994.
25. 25 Thompson EA, Deeb S, Walker D, Motulsky AG. The detection of linkage disequilibrium between closely linked markers. RLFPs at the AI-CII apolipoprotein genes. Am J Hum Genet 1988; 42: 113-24.
26. 26 Spielman RS, McGinnis RE, Ewens WJ. Transmission test for linkage disequilibrium. The insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 1993; 52: 506-516.
27. 27 Wang K, Bohren KM, Gabbay KH. Characterization of the human aldose reductase gene promoter. J Biol Chem 1993; 268: 16052-16058.
28. 28 Ko BCB, Ruepp B, Bohren KM, Gabbay KH, Chung SSM. Identification and characterization of multiple osmotic response sequences in the human aldose reductase gene. J Biol Chem 1997; 272: 16431-16437.
29. 29 Heesom AE, Graham A, Millward BA, Demaine AG. Characterisation of the osmotic response elements of the aldose reductase gene in type I diabetic patients. Diabetologia 1998; 41 (Suppl 1): A295.
30. 30 Morton NE, Collins A. Tests and estimates of allelic association in complex inheritance. Proc Natl Acad Sci USA 1998; 95: 11389-11393.
31. 31 Simonet WS, Bucay N, Lauer SJ, Taylor JM. A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice. J Biol Chem 1993; 268: 8221-8229.
32. 32 Moczulski DK, Burak W, Doria A, Zychma M, Zukowska-Szczechowska E, Warram JH et al. The role of aldose reductase gene in the susceptibility to diabetic nephropathy in Type II (non-insulin-dependent) diabetes mellitus. Diabetologia 1999; 42: 94-97.