메뉴 건너뛰기




Volumn 43, Issue 3, 2000, Pages 169-174

Prostasomes: Current concepts

Author keywords

Infertility; Male factor; Prostasomes; Prostate

Indexed keywords

CALCIUM; CHOLESTEROL; CHROMOGRANIN A; CHROMOGRANIN B; ENZYME; LIPID; NEUROPEPTIDE Y; NUCLEIC ACID; SPHINGOMYELIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

EID: 0034013535     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(20000515)43:3<169::AID-PROS2>3.0.CO;2-D     Document Type: Article
Times cited : (75)

References (62)
  • 1
    • 0018197793 scopus 로고
    • An Mg2+ and Ca2+-stimulated adenosine triphosphatase in human prostatic fluid - Part II
    • Ronquist G, Brody I, Gottfries A, Stegmayr B. An Mg2+ and Ca2+-stimulated adenosine triphosphatase in human prostatic fluid - part II. Andrologia 1978;10:427-433.
    • (1978) Andrologia , vol.10 , pp. 427-433
    • Ronquist, G.1    Brody, I.2    Gottfries, A.3    Stegmayr, B.4
  • 2
    • 0017902157 scopus 로고
    • An Mg2+ and Ca2+-stimulated adenosine triphosphatase in human prostatic fluid - Part I
    • Ronquist G, Brody I, Gottfries A, Stegmayr B. An Mg2+ and Ca2+-stimulated adenosine triphosphatase in human prostatic fluid - part I. Andrologia 1978;10:261-272.
    • (1978) Andrologia , vol.10 , pp. 261-272
    • Ronquist, G.1    Brody, I.2    Gottfries, A.3    Stegmayr, B.4
  • 4
    • 0024460831 scopus 로고
    • Human prostasome membranes exhibit very high cholesterol/phospholipid ratios yielding high molecular ordering
    • Arvidson G, Ronquist G, Wikander G, Ojteg AC. Human prostasome membranes exhibit very high cholesterol/phospholipid ratios yielding high molecular ordering. Biochim Biophys Acta 1989;984:167-173.
    • (1989) Biochim Biophys Acta , vol.984 , pp. 167-173
    • Arvidson, G.1    Ronquist, G.2    Wikander, G.3    Ojteg, A.C.4
  • 5
    • 0022257512 scopus 로고
    • The prostasome: Its secretion and function in man
    • Ronquist G, Brody I. The prostasome: its secretion and function in man. Biochim Biophys Acta 1985;822:203-218.
    • (1985) Biochim Biophys Acta , vol.822 , pp. 203-218
    • Ronquist, G.1    Brody, I.2
  • 6
    • 0021006952 scopus 로고
    • Ultrastructural localization of the prostasome - An organelle in human seminal plasma
    • Brody I, Ronquist G, Gottfries A. Ultrastructural localization of the prostasome - an organelle in human seminal plasma. Ups J Med Sci 1983:88:63-80.
    • (1983) Ups J Med Sci , vol.88 , pp. 63-80
    • Brody, I.1    Ronquist, G.2    Gottfries, A.3
  • 8
    • 0342617732 scopus 로고    scopus 로고
    • Anti-human prostasome MAB 78 binds to antigen distinct from PSA and PAP
    • Jin M, Nilsson BO, Larsson A, Hellman U, Ronquist G. Anti-human prostasome MAB 78 binds to antigen distinct from PSA and PAP. J Urol 1997;157:1932-1936.
    • (1997) J Urol , vol.157 , pp. 1932-1936
    • Jin, M.1    Nilsson, B.O.2    Larsson, A.3    Hellman, U.4    Ronquist, G.5
  • 9
    • 0030333877 scopus 로고    scopus 로고
    • Immunolocalization of prostasomes in the human prostate
    • Nilsson BO, Jin M, Ronquist G. Immunolocalization of prostasomes in the human prostate. Ups J Med Sci 1996;101:149-157.
    • (1996) Ups J Med Sci , vol.101 , pp. 149-157
    • Nilsson, B.O.1    Jin, M.2    Ronquist, G.3
  • 10
    • 0032940456 scopus 로고    scopus 로고
    • Identification of dipeptidyl peptidase IV as the antigen of a monoclonal anti-prostasome antibody
    • Schrimpf SP, Hellman U, Carlsson L, Larsson A, Ronquist G, Nilsson BO. Identification of dipeptidyl peptidase IV as the antigen of a monoclonal anti-prostasome antibody. Prostate 1999; 38:35-39.
    • (1999) Prostate , vol.38 , pp. 35-39
    • Schrimpf, S.P.1    Hellman, U.2    Carlsson, L.3    Larsson, A.4    Ronquist, G.5    Nilsson, B.O.6
  • 12
    • 0033560076 scopus 로고    scopus 로고
    • Distribution of prostasomes in neoplastic epithelial prostate cells
    • Nilsson BO, Egevad L, Jin M, Ronquist G, Busch C. Distribution of prostasomes in neoplastic epithelial prostate cells. Prostate 1999;39:36-40.
    • (1999) Prostate , vol.39 , pp. 36-40
    • Nilsson, B.O.1    Egevad, L.2    Jin, M.3    Ronquist, G.4    Busch, C.5
  • 13
    • 0023522778 scopus 로고
    • Phospholipase A2 activity in prostasomes from human seminal plasma
    • Lindahl M, Tagesson C, Ronquist G. Phospholipase A2 activity in prostasomes from human seminal plasma. Urol Int 1987;42: 385-389.
    • (1987) Urol Int , vol.42 , pp. 385-389
    • Lindahl, M.1    Tagesson, C.2    Ronquist, G.3
  • 14
    • 0024212333 scopus 로고
    • Zinc ion stimulation of ATP cleavage by prostasomes from human seminal plasma
    • Ronquist G. Zinc ion stimulation of ATP cleavage by prostasomes from human seminal plasma. Urol Int 1988;43:334-340.
    • (1988) Urol Int , vol.43 , pp. 334-340
    • Ronquist, G.1
  • 15
    • 0023729939 scopus 로고
    • Prostasome membrane associated enzyme activities and semen parameters in men attending an infertility clinic
    • Ronquist G, Frithz G, Jansson A. Prostasome membrane associated enzyme activities and semen parameters in men attending an infertility clinic. Urol Int 1988;43:133-138.
    • (1988) Urol Int , vol.43 , pp. 133-138
    • Ronquist, G.1    Frithz, G.2    Jansson, A.3
  • 16
    • 0023183038 scopus 로고
    • Effect of modulators on prostasome membrane-bound ATPase in human seminal plasma
    • Ronquist G. Effect of modulators on prostasome membrane-bound ATPase in human seminal plasma. Eur J Clin Invest 1987; 17:231-236.
    • (1987) Eur J Clin Invest , vol.17 , pp. 231-236
    • Ronquist, G.1
  • 17
    • 0025647424 scopus 로고
    • Isoenzyme pattern of lactate dehydrogenase associated with human prostasomes
    • Olsson I, Ronquist G. Isoenzyme pattern of lactate dehydrogenase associated with human prostasomes. Urol Int 1990;45:346-349.
    • (1990) Urol Int , vol.45 , pp. 346-349
    • Olsson, I.1    Ronquist, G.2
  • 18
    • 0020467462 scopus 로고
    • A zinc-dependent peptidase in prostatic organelles present in seminal
    • Laurell CB, Weiber H, Ohlsson K, Rannevik C. A zinc-dependent peptidase in prostatic organelles present in seminal. Clin Chim Acta 1982;126:161-170.
    • (1982) Clin Chim Acta , vol.126 , pp. 161-170
    • Laurell, C.B.1    Weiber, H.2    Ohlsson, K.3    Rannevik, C.4
  • 19
    • 0020537468 scopus 로고
    • Gamma-glutamyltransferase bound to prostatic subcellular organelles and in free form in human seminal plasma
    • Lilja H, Weiber H. Gamma-glutamyltransferase bound to prostatic subcellular organelles and in free form in human seminal plasma. Scand J Clin Lab Invest 1983;43:307-312.
    • (1983) Scand J Clin Lab Invest , vol.43 , pp. 307-312
    • Lilja, H.1    Weiber, H.2
  • 20
    • 0027186086 scopus 로고
    • Characteristics of membrane-bound 5′-nucleotidase on human prostasomes
    • Fabiani R, Ronquist G. Characteristics of membrane-bound 5′-nucleotidase on human prostasomes. Clin Chim Acta 1993;216: 175-182.
    • (1993) Clin Chim Acta , vol.216 , pp. 175-182
    • Fabiani, R.1    Ronquist, G.2
  • 21
    • 0021740378 scopus 로고
    • Prostatic origin of fucosyl transferase in human seminal plasma - A study on healthy controls and on men with infertility or with prostatic cancer
    • Ronquist G, Stegmayr B. Prostatic origin of fucosyl transferase in human seminal plasma - a study on healthy controls and on men with infertility or with prostatic cancer. Urol Res 1984;12: 243-247.
    • (1984) Urol Res , vol.12 , pp. 243-247
    • Ronquist, G.1    Stegmayr, B.2
  • 22
    • 0030831291 scopus 로고    scopus 로고
    • Transfer of CD26/dipeptidyl peptidase IV (E.C. 3.5.4.4) from prostasomes to sperm
    • Arienti G, Polci A, Carlini E, Palmerini CA. Transfer of CD26/ dipeptidyl peptidase IV (E.C. 3.5.4.4) from prostasomes to sperm. FEBS Lett 1997;410:343-346.
    • (1997) FEBS Lett , vol.410 , pp. 343-346
    • Arienti, G.1    Polci, A.2    Carlini, E.3    Palmerini, C.A.4
  • 23
    • 0027244148 scopus 로고
    • Hematopoietic differentiation antigens that are membrane-associated enzymes
    • Shipp MA, Look AT. Hematopoietic differentiation antigens that are membrane-associated enzymes. Blood 1993:82:1052-1070.
    • (1993) Blood , vol.82 , pp. 1052-1070
    • Shipp, M.A.1    Look, A.T.2
  • 24
    • 0031747748 scopus 로고    scopus 로고
    • Activation of coagulation factor X in human semen
    • Carson SD, De Jonge CJ. Activation of coagulation factor X in human semen. J Androl 1998;19:289-294.
    • (1998) J Androl , vol.19 , pp. 289-294
    • Carson, S.D.1    De Jonge, C.J.2
  • 26
    • 0031056581 scopus 로고    scopus 로고
    • Distribution and subcellular localization of a lysosome-associated protein in human genital organs
    • Aumuller G, Renneberg H, Hasilik A. Distribution and subcellular localization of a lysosome-associated protein in human genital organs. Cell Tissue Res 1997;287:335-342.
    • (1997) Cell Tissue Res , vol.287 , pp. 335-342
    • Aumuller, G.1    Renneberg, H.2    Hasilik, A.3
  • 27
    • 0027433570 scopus 로고
    • Arachidonic acid 15-lipoxygenase and traces of E prostaglandins in purified human prostasomes
    • Oliw EH, Fabiani R, Johansson L, Ronquist G. Arachidonic acid 15-lipoxygenase and traces of E prostaglandins in purified human prostasomes. J Reprod Fertil 1993;99:195-199.
    • (1993) J Reprod Fertil , vol.99 , pp. 195-199
    • Oliw, E.H.1    Fabiani, R.2    Johansson, L.3    Ronquist, G.4
  • 28
    • 0024603803 scopus 로고
    • Metabolism of polyunsaturated fatty acids by an (n - 6)-lipoxygenase associated with human ejaculates
    • Oliw EH, Sprecher H. Metabolism of polyunsaturated fatty acids by an (n - 6)-lipoxygenase associated with human ejaculates. Biochim Biophys Acta 1989;1002:283-291.
    • (1989) Biochim Biophys Acta , vol.1002 , pp. 283-291
    • Oliw, E.H.1    Sprecher, H.2
  • 29
    • 0029826137 scopus 로고    scopus 로고
    • Prostasomes are neuroendocrine-like vesicles in human semen
    • Stridsberg M, Fabiani R, Lukinius A, Ronquist G. Prostasomes are neuroendocrine-like vesicles in human semen. Prostate 1996; 29:287-295.
    • (1996) Prostate , vol.29 , pp. 287-295
    • Stridsberg, M.1    Fabiani, R.2    Lukinius, A.3    Ronquist, G.4
  • 30
    • 0029145661 scopus 로고
    • Association of some hydrolytic enzymes with the prostasome membrane and their differential responses to detergent and PIPLC treatment
    • Fabiani R, Ronquist G. Association of some hydrolytic enzymes with the prostasome membrane and their differential responses to detergent and PIPLC treatment. Prostate 1995;27:95-101.
    • (1995) Prostate , vol.27 , pp. 95-101
    • Fabiani, R.1    Ronquist, G.2
  • 31
    • 0344766114 scopus 로고    scopus 로고
    • Hamster sperm antigen P26h is a phosphatidylinositol-anchored protein
    • Legare C, Berube B, Boue F, Lefievre L, Morales CR. Hamster sperm antigen P26h is a phosphatidylinositol-anchored protein. Mol Reprod Dev 1999;52:225-233.
    • (1999) Mol Reprod Dev , vol.52 , pp. 225-233
    • Legare, C.1    Berube, B.2    Boue, F.3    Lefievre, L.4    Morales, C.R.5
  • 32
    • 0029865964 scopus 로고    scopus 로고
    • GPI-anchored complement regulatory proteins in seminal plasma. An analysis of their physical condition and the mechanisms of their binding to exogenous cells
    • Rooney IA, Heuser JE, Atkinson JP. GPI-anchored complement regulatory proteins in seminal plasma. An analysis of their physical condition and the mechanisms of their binding to exogenous cells. J Clin Invest 1996;97:1675-1686.
    • (1996) J Clin Invest , vol.97 , pp. 1675-1686
    • Rooney, I.A.1    Heuser, J.E.2    Atkinson, J.P.3
  • 33
    • 0027478377 scopus 로고
    • Physiologic relevance of the membrane attack complex inhibitory protein CD59 in human seminal plasma: CD59 is present on extracellular organelles (prostasomes), binds cell membranes, and inhibits complement-mediated lysis
    • Rooney IA, Atkinson JP, Krul ES, Schonfeld G, Polakoski K, Saffitz JE, Morgan BP. Physiologic relevance of the membrane attack complex inhibitory protein CD59 in human seminal plasma: CD59 is present on extracellular organelles (prostasomes), binds cell membranes, and inhibits complement-mediated lysis. J Exp Med 1993;177:1409-1420.
    • (1993) J Exp Med , vol.177 , pp. 1409-1420
    • Rooney, I.A.1    Atkinson, J.P.2    Krul, E.S.3    Schonfeld, G.4    Polakoski, K.5    Saffitz, J.E.6    Morgan, B.P.7
  • 34
    • 0024286552 scopus 로고
    • Structural and functional roles of glycosylphosphatidylinositol in
    • Low MG, Saltiel AR. Structural and functional roles of glycosylphosphatidylinositol in. Science 1988;239:268-275.
    • (1988) Science , vol.239 , pp. 268-275
    • Low, M.G.1    Saltiel, A.R.2
  • 35
    • 0024468669 scopus 로고
    • A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells
    • Lisanti MP, Caras IW, Davitz MA, Rodriguez-Boulan E. A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells. J Cell Biol 1989;109:2145-2156.
    • (1989) J Cell Biol , vol.109 , pp. 2145-2156
    • Lisanti, M.P.1    Caras, I.W.2    Davitz, M.A.3    Rodriguez-Boulan, E.4
  • 36
    • 0028965245 scopus 로고
    • Membrane cofactor protein (CD46) in seminal plasma is a prostasome-bound form with complement regulatory activity and measles virus neutralizing activity
    • Kitamura M, Namiki M, Matsumiya K, Tanaka K, Matsumoto M, Hara T, Kiyohara H, Okabe M, Okuyama A, Seya T. Membrane cofactor protein (CD46) in seminal plasma is a prostasome-bound form with complement regulatory activity and measles virus neutralizing activity. Immunology 1995;84:626-632.
    • (1995) Immunology , vol.84 , pp. 626-632
    • Kitamura, M.1    Namiki, M.2    Matsumiya, K.3    Tanaka, K.4    Matsumoto, M.5    Hara, T.6    Kiyohara, H.7    Okabe, M.8    Okuyama, A.9    Seya, T.10
  • 37
    • 0031684634 scopus 로고    scopus 로고
    • Zinc enrichment in prostasomes
    • Ronquist G. Zinc enrichment in prostasomes [letter]. Int J Androl 1998;21:233-234.
    • (1998) Int J Androl , vol.21 , pp. 233-234
    • Ronquist, G.1
  • 38
    • 0028725566 scopus 로고
    • Functional and biochemical characteristics of human prostasomes. Minireview based on a doctoral thesis
    • Fabiani R. Functional and biochemical characteristics of human prostasomes. Minireview based on a doctoral thesis. Ups J Med Sci 1994;99:73-111.
    • (1994) Ups J Med Sci , vol.99 , pp. 73-111
    • Fabiani, R.1
  • 39
    • 0022903023 scopus 로고
    • Prostasomes in human semen contain ADP and GDP
    • Ronquist G, Frithz GG. Prostasomes in human semen contain ADP and GDP. Acta Eur Fertil 1986;17:273-276.
    • (1986) Acta Eur Fertil , vol.17 , pp. 273-276
    • Ronquist, G.1    Frithz, G.G.2
  • 40
    • 84907130116 scopus 로고
    • Nucleic acid association to human prostasomes
    • Olsson I, Ronquist G. Nucleic acid association to human prostasomes. Arch Androl 1990;24:1-10.
    • (1990) Arch Androl , vol.24 , pp. 1-10
    • Olsson, I.1    Ronquist, G.2
  • 41
    • 80051736639 scopus 로고    scopus 로고
    • Adherence of human prostasomes to mouse spermatozoa and their displacement by monoclonal antibodies as revealed by free zone electrophoresis
    • Ronquist G, Fabiani R, Jin M, Nilsson BO, Elenbring K, Hjerten S. Adherence of human prostasomes to mouse spermatozoa and their displacement by monoclonal antibodies as revealed by free zone electrophoresis. Arch Androl 1996;36:101-107.
    • (1996) Arch Androl , vol.36 , pp. 101-107
    • Ronquist, G.1    Fabiani, R.2    Jin, M.3    Nilsson, B.O.4    Elenbring, K.5    Hjerten, S.6
  • 42
    • 84907124130 scopus 로고
    • Interaction between prostasomes and spermatozoa from human semen
    • Ronquist G, Nilsson BO, Hjerten S. Interaction between prostasomes and spermatozoa from human semen. Arch Androl 1990; 24:147-157.
    • (1990) Arch Androl , vol.24 , pp. 147-157
    • Ronquist, G.1    Nilsson, B.O.2    Hjerten, S.3
  • 43
    • 0031034693 scopus 로고    scopus 로고
    • Fusion of human sperm to prostasomes at acidic pH
    • Arienti G, Carlini E, Palmerini CA. Fusion of human sperm to prostasomes at acidic pH. J Membr Biol 1997;155:89-94.
    • (1997) J Membr Biol , vol.155 , pp. 89-94
    • Arienti, G.1    Carlini, E.2    Palmerini, C.A.3
  • 46
    • 0030610318 scopus 로고    scopus 로고
    • Prostasome fraction of human seminal plasma prevents sperm from becoming acrosomally responsive to the agonist progesterone
    • Cross NL, Mahasreshti P. Prostasome fraction of human seminal plasma prevents sperm from becoming acrosomally responsive to the agonist progesterone. Arch Androl 1997;39:39-44.
    • (1997) Arch Androl , vol.39 , pp. 39-44
    • Cross, N.L.1    Mahasreshti, P.2
  • 47
    • 0029656158 scopus 로고    scopus 로고
    • Human seminal plasma prevents sperm from becoming acrosomally responsive to the agonist, progesterone-cholesterol is the major inhibitor
    • Cross NL. Human seminal plasma prevents sperm from becoming acrosomally responsive to the agonist, progesterone-cholesterol is the major inhibitor. Biol Reprod 1996;54:138-145.
    • (1996) Biol Reprod , vol.54 , pp. 138-145
    • Cross, N.L.1
  • 49
    • 80051720080 scopus 로고    scopus 로고
    • Motility stimulant effects of prostasome inclusion in swim-up medium on cryopreserved human spermatozoa
    • Carlsson L, Ronquist G, Stridsberg M, Johansson L. Motility stimulant effects of prostasome inclusion in swim-up medium on cryopreserved human spermatozoa. Arch Androl 1997;38: 215-221.
    • (1997) Arch Androl , vol.38 , pp. 215-221
    • Carlsson, L.1    Ronquist, G.2    Stridsberg, M.3    Johansson, L.4
  • 51
    • 0028670222 scopus 로고
    • Promotive effect by prostasomes on normal human spermatozoa exhibiting no forward motility due to buffer washings
    • Fabiani R, Johansson L, Lundkvist O, Ulmsten U, Ronquist G. Promotive effect by prostasomes on normal human spermatozoa exhibiting no forward motility due to buffer washings. Eur J Obstet Gynecol Reprod Biol 1994;57:181-188.
    • (1994) Eur J Obstet Gynecol Reprod Biol , vol.57 , pp. 181-188
    • Fabiani, R.1    Johansson, L.2    Lundkvist, O.3    Ulmsten, U.4    Ronquist, G.5
  • 52
    • 0028096591 scopus 로고
    • Enhanced recruitment of motile spermatozoa by prostasome inclusion in swim-up medium
    • Fabiani R, Johansson L, Lundkvist O, Ronquist G. Enhanced recruitment of motile spermatozoa by prostasome inclusion in swim-up medium. Hum Reprod 1994;9:1485-1489.
    • (1994) Hum Reprod , vol.9 , pp. 1485-1489
    • Fabiani, R.1    Johansson, L.2    Lundkvist, O.3    Ronquist, G.4
  • 53
    • 0020384213 scopus 로고
    • Promotive effect on human sperm progressive motility by prostasomes
    • Stegmayr B, Ronquist G. Promotive effect on human sperm progressive motility by prostasomes. Urol Res 1982;10:253-257.
    • (1982) Urol Res , vol.10 , pp. 253-257
    • Stegmayr, B.1    Ronquist, G.2
  • 56
  • 57
    • 0029144803 scopus 로고
    • Immunosuppressive mechanisms in semen: Implications for contraception
    • Kelly RW. Immunosuppressive mechanisms in semen: implications for contraception. Hum Reprod 1995;10:1686-1693.
    • (1995) Hum Reprod , vol.10 , pp. 1686-1693
    • Kelly, R.W.1
  • 58
    • 0027052489 scopus 로고
    • Immunosuppression by human seminal plasma - Extracellular organelles (prostasomes) modulate activity of phagocytic cells
    • Skibinski G, Kelly RW, Harkiss D, James K. Immunosuppression by human seminal plasma - extracellular organelles (prostasomes) modulate activity of phagocytic cells. Am J Reprod Immunol 1992;28:97-103.
    • (1992) Am J Reprod Immunol , vol.28 , pp. 97-103
    • Skibinski, G.1    Kelly, R.W.2    Harkiss, D.3    James, K.4
  • 60
    • 0031828567 scopus 로고    scopus 로고
    • Antioxidant capacity of prostasomes in human semen
    • Saez F, Motta C, Boucher D, Grizard G. Antioxidant capacity of prostasomes in human semen. Mol Hum Reprod 1998;4:667-672.
    • (1998) Mol Hum Reprod , vol.4 , pp. 667-672
    • Saez, F.1    Motta, C.2    Boucher, D.3    Grizard, G.4
  • 61
    • 0027373018 scopus 로고
    • Complement in human reproduction: Activation and control
    • Rooney IA, Oglesby TJ, Atkinson JP. Complement in human reproduction: activation and control. Immunol Res 1993;12:276-294.
    • (1993) Immunol Res , vol.12 , pp. 276-294
    • Rooney, I.A.1    Oglesby, T.J.2    Atkinson, J.P.3
  • 62
    • 0023789254 scopus 로고
    • Preliminary results using pentoxifylline in a pronuclear stage tubal transfer (PROST) program for severe male factor infertility
    • Yovich JM, Edirisinghe WR, Cummins JM. Preliminary results using pentoxifylline in a pronuclear stage tubal transfer (PROST) program for severe male factor infertility. Fertil Steril 1988;50:179-181.
    • (1988) Fertil Steril , vol.50 , pp. 179-181
    • Yovich, J.M.1    Edirisinghe, W.R.2    Cummins, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.