Monoclonal antibodies against human prostasomes

Prostate

Volumn 35, Issue 3, 1998, Pages 178-184

  Nilsson, B Ove ^a   Jin, Meishan ^a   Einarsson, Barbro ^a   Persson, Bo Eric ^b   Ronquist, Gunnar ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Immunoblot; Immunohistochemistry; Intrasplenic immunization

Indexed keywords

ANTIGEN; MONOCLONAL ANTIBODY; PYROXYLIN;

ARTICLE; EJACULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROSTATE; PROSTATE SECRETION; SEQUENCE ANALYSIS; TISSUE SPECIFICITY;

ANIMALS; ANTIBODIES, MONOCLONAL; HUMANS; IMMUNIZATION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MICE; PROSTATE; SEMEN; SEQUENCE ANALYSIS; SPERMATOZOA; SPLEEN;

EID: 0032524978     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(19980515)35:3<178::AID-PROS3>3.0.CO;2-D     Document Type: Article

References (41)

1. Ronquist G, Brody I: The prostasome: Its secretion and function in man. Biochim Biophys Acta 1985;822:203-218.
2. Fabiani R: Functional and biochemical characteristics of human prostasomes. Ups J Med Sci 1994;99:73-112.
3. 2+-stimulated adenosine triphosphatase in human prostatic fluid. Andrologia 1978;10:261-272, 427-433.
4. Brody I, Gottfries A, Ronquist G: Ultrastructural localization of the prostasome-An organelle in human seminal plasma. Ups J Med Sci 1983;88:63-80.
5. Kelly RW, Holland P, Skibinski G, Harrison C, McMillan L, Hargreave T, James K: Extracellular organelles (prostasomes) are immunosuppressive components of human semen. Clin Exp Immunol 1991;86:550-556.
6. Ronquist G, Nilsson BO, Hjertén S: Interaction between prostasomes and spermatozoa from human semen. Arch Androl 1990; 24:147-157.
7. Skibinski G, Kelly RW, Harkiss D, James K: Immunosuppression by human seminal plasma - Extracellular organelles (prostasomes) modulate activity of phagocytic cells. Am J Reprod Immunol Microbiol 1992;28:97-103.
8. Lazarevic M, Skibinski G, Kelly RW, James K: Immunomodulatory effects of extracellular secretory vesicles isolated from bovine semen. Vet Immunol Immunopathol 1995;44:237-250.
9. Rooney IA, Heuser JE, Atkinson JP: GPI-anchored complement regulatory proteins in seminal plasma. An analysis of their physical condition and the mechanisms of their binding to exogenous cells. J Clin Invest 1996;97:1675-1686.
10. Kitamura M, Namiki M, Matsumiya K, Tanaka K, Matsumoto M, Hara T, Kiyohara H, Okabe M, Okuyama A, Seya T: Membrane cofactor protein (CD46) in seminal plasma is a prostasome-bound form with complement regulatory activity and measles virus neutralizing activity. Immunology 1995;84:626-632.
11. Simpson KL, Holmes CH: Presence of the complement-regulatory protein membrane cofactor protein (MCP, CD46) as a membrane-associated product in seminal plasma. J Reprod Fertil 1994;102:419-424.
12. Rooney IA, Atkinson JP, Krul ES, Schonfeld G, Polakoski K, Saffitz JE, Morgan BP: Physiologic relevance of the membrane attack complex inhibitory protein CD59 in human seminal plasma: CD59 is present on extracellular organelles (prostasomes), binds cell membranes, and inhibits complement-mediated lysis. J Exp Med 1993;177:1409-1420.
13. Ronquist G, Fabiani R, Jin M, Nilsson BO, Elenbring K, Hjertén S: Adherence of human prostasomes to mouse spermatozoa and their displacement by monoclonal antibodies as revealed by free zone electrophoresis. Arch Androl 1996;36:101-107.
14. Kelly RW: Immunosuppressive mechanisms in semen: Implications for contraception. Hum Reprod 1995;10:1686-1693.
15. Kelly RW: Seminal plasma immunosuppressive activity: The Achilles heel of reproduction. Int J Androl 1991;14:243-247.
16. Fabiani R, Johansson L, Lundkvist Ö, Ulmsten U, Ronquist G: Promotive effect by prostasomes on normal human spermatozoa exhibiting no forward motility due to buffer washings. Eur J Obstet Gynecol Reprod Biol 1994;57:181-188.
17. Stegmayr B, Ronquist G: Promotive effect on human sperm progressive motility by prostasomes. Urol Res 1982;10:253-257.
18. Fabiani R, Johansson L, Lundkvist Ö, Ronquist G: Enhanced recruitment of motile spermatozoa by prostasome inclusion in swim-up medium. Hum Reprod 1994;9:1485-1489.
19. 2+ dependent adenosine triphosphatase and secretory granules and vesicles in human seminal plasma. Scand J Urol Nephrol 1981;15:90-95.
20. Ronquist G, Stegmayr B: Prostatic origin of fucosyl transferase in human seminal plasma. A study on healthy controls and on men with infertility or with prostatic cancer. Urol Res 1984;12: 243-247.
21. Skibinski G, Kelly RW, James K: Expression of a common secretory granule specific protein as a marker for the extracellular organelles (prostasomes) in human semen. Fertil Steril 1994;61: 755-759.
22. Hatskelzon L, Dalal BI, Shalev A, Robertson C, Gerrard JM: Wide distribution of granulophysin epitopes in granules of human tissues. Lab Invest 1993;68:509-519.
23. Stridsberg M, Fabiani R, Lukinius A, Ronquist G: Prostasomes are neuroendocrine-like vesicles in human semen. Prostate 1996; 29:287-295.
24. Renneberg H, Konrad L, Dammshäuser I, Seitz J, Aumuller G: Immunohistochemistry of prostasomes from human semen. Prostate 1997;30:98-106.
25. Nilsson BO, Larsson A: Intrasplenic immunization with minute amounts of antigen. Immunol Today 1990;11:10-12.
26. Nilsson BO, Svalander PC, Larsson A: Immunization of mice and rabbits by intrasplenic deposition of nanogram quantities of protein attached to Sepharose beads or nitrocellulose paper strips. J Immunol Methods 1987;99:67-75.
27. Fabiani R, Ronquist G: Association of some hydrolytic enzymes with the prostasome membrane and their differential responses to detergent and PIPLC treatment. Prostate 1995;27:95-101.
28. Persson BE, Ronquist G: Evidence for a mechanistic association between nonbacterial prostatitis and levels of urate and creatinine in expressed prostatic secretion. J Urol 1996;155:958-960.
29. Shi SR, Key ME, Kalra KL: Antigen retrieval in formalin-fixed, paraffin-embedded tissues: An enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J Histochem Cytochem 1991;39:741-748.
30. Nilsson BO, Jin M, Ronquist G: Immunolocalization of prostasomes in the human prostate. Ups J Med Sci 1996;101:149-158.
31. Arvidson G, Ronquist G, Wikander G, Öjteg AC: Human prostasome membranes exhibit very high cholesterol/phospholipid ratios yielding high molecular ordering. Biochim Biophys Acta 1989;984:167-173.
32. Lindahl M, Tagesson C, Ronquist G: Phospholipase A2 activity in prostasomes from human seminal plasma. Urol Int 1987;42: 385-389.
33. Ronquist G: Effects of modulators on prostasome membrane-bound ATPase in human seminal plasma. Eur J Clin Invest 1987; 17:231-236.
34. Lilja H, Weiber H: g-glutamyltransferase bound to prostatic subcellular organelles and in free form in human seminal plasma. Scand J Clin Lab Invest 1983;43:307-312.
35. Olsson I, Ronquist G: Isoenzyme pattern of lactate dehydrogenase associated with human prostasomes. Urol Int 1990;45:346-349.
36. Krassnigg F, Niederhauser H, Placzek H, Frick J, Schill WB: Investigations on the functional role of angiotensin converting enzyme (ACE) in human seminal plasma. Adv Exp Med Biol 1986;198:477-485.
37. de Meester I, Vanhoof G, Lambeir AM, Scharpe S: Use of immobilized adenosine deaminase (EC 3.5.4.4) for the rapid purification of native human CD26/dipeptidyl peptidase IV (EC 3.4.14.5). J Immunol Methods 1996;189:99-105.
38. Frenette G, Dubé JY, Marcotte JR, Tremblay RR: Arginine esterase from isolated dog prostate secretory granules is fully active enzymatically. Can J Physiol Pharmacol 1985;63:1603-1607.
39. 2+-ATPase activity in membrane vesicles from ejaculated ram seminal plasma. Arch Androl 1982;9:147-157.
40. Jin M, Nilsson BO, Larsson A, Hellman U, Ronquist G: The anti-human prostasome MAB 78 binds to an antigen distinct from PSA and PAP. J Urol 1997;157:1932-1936.
41. Winkler H, Fischer-Colbrie R: The chromogranins A and B: The first 25 years and future perspectives. Neuroscience 1992;49: 497-528.