Antibodies to different peptides in osteopontin reveal complexities in the various secreted forms

Journal of Cellular Biochemistry

Volumn 77, Issue 3, 2000, Pages 487-498

  Kon, Shigeyuki ^a   Maeda, Masahiro ^b   Segawa, Tatsuya ^b   Hagiwara, Yoshiaki ^b   Horikoshi, Yuko ^b   Chikuma, Shunsuke ^a   Tanaka, Kumiko ^a   Rashid, Mohammod Mizanur ^a   Inobe, Manabu ^a   Chambers, Ann F ^c   Uede, Toshimitsu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b Immuno Biological Laboratories Co Ltd   (Japan)

^c LONDON REGIONAL CANCER PROGRAM   (Canada)

Author keywords

ELISA; Isoforms; Osteopontin; Tumor cells; Urine

Indexed keywords

CALCIUM BINDING PROTEIN; MONOCLONAL ANTIBODY; OSTEOPONTIN; POLYCLONAL ANTIBODY; PROTEIN ANTIBODY; SYNTHETIC PEPTIDE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; PROTEIN POLYMORPHISM; PROTEIN PURIFICATION; PROTEIN SECRETION; TUMOR CELL LINE; URINE;

ADULT; ANIMALS; ANTIBODIES; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MALE; MICE; OSTEOPONTIN; PLASMIDS; PROTEIN ISOFORMS; RABBITS; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SIALOGLYCOPROTEINS; THROMBIN; TUMOR CELLS, CULTURED;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0034013170     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(20000601)77:3<487::AID-JCB13>3.0.CO;2-8     Document Type: Article

References (43)

1. Atkins K, Berry JE, Zhang WZ, Harris JF, Chambers AF, Simpson RU, Somermann MJ. 1998. Coordinate expression of OPN and associated receptors during monocyte/ macrophage differentiation of HL-60 cells. J Cell Physiol 175:229-239.
2. Bautista DS, Saad Z, Chambers AF, Tonkin KS, O'Malley FP, Singhal H, Tokmakejian S, Bramwell V, Harris JF. 1996. Quantification of osteopontin in human plasma with an ELISA: basa levels in pre- and postmenopausal women. Clin Biochem 29:231-239.
3. Bautista DS, Xuan JW, Hota C, Chambers AF, Harris JF. 1994. Inhibition of arg-gly-asp (RGD)-mediated cell adhesion to osteopontin by a monoclonal antibody against osteopontin. J Biol Chem 269:23280-23285.
4. Carlson I, Tognazzi K, Manseau EM, Dvorak HF, Brown LF. 1997. Osteopontin is strongly expressed by histiocytes in granulomas of diverse etiology. Lab Invest 77: 103-108.
5. Chambers AF, Hota C, Prince CW. 1993. Adhesion of metastatic, ras-transformed NIH3T3 cells to osteopontin, fibronectin, and laminin. Cancer Res 53:701-706.
6. Chambers AF, Wilson SM, Kerkvliet N, O'Malley FP, Harris JF, Gasson AG, 1996. Osteopontin expression in lung cancer. Lung Cancer 15:311-323.
7. Denhardt DT, Guo X. 1993. Osteopontin: a protein with diverse functions. FASEB J 7:1475-1482.
8. Fitzpatrick LA, Severson A, Edwards WD, Ingram RT. 1994. Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis. J Clin Invest 94:1597-1604.
9. Hirota S, Imakita M, Kohri K, Ito A, Morii E, Adachi S, Kim H-M, Kitamura Y, Yutani C, Nomura S. 1993. Expression of osteopontin mRNA by macrophages in atherosclerotic plaques. A possible association with calcification. Am J Pathol 143:1003-1008.
10. Hotta H, Kon S, Katagiri YU, Tosa N, Tsukamoto T, Chambers AF, Uede T. 1999. Detection of various epitopes of murine osteopontin by monoclonal antibodies. Biochem Biophys Res Commun 257:6-11.
11. Ikeda T, Shirasawa T, Esaki Y, Yoshiki S, Hirokawa K 1993. Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta. J Clin Invest 92:2814-2820.
12. Imai Y, Kakinoki Y, Takizawa N, Nakamura K, Shima H, Kikuchi K. 1999. Up-regulation of nuclear PP1 alpha and PP1 delta in hepatoma cells. Int J Oncol 14:121-126.
13. Katagiri Y, Murakami M, Mori K, Iizuka J, Hara T, Tanaka K, Jia WY, Chambers AF, Uede T. 1996. Non-RGD domains of osteopontin promote cell adhesion without involving αv integrins. J Cell Biochem 62:123-131.
14. Katagiri YU, Sleeman J, Fujii H, Herrlich P, Hotta H, Tanaka K, Chikuma S, Yagita H, Okumura K, Muramatsu M, Saiki I, Chambers AF, Uede T. 1999. CD44 variants but not CD44s cooperate with beta-1 containing integrins to permit cells to bind to osteopontin independently of RGD, thereby stimulating cell motility and chemotaxis. Cancer Res 59:219-226.
15. Kiefer MC, Bauer DM, Barr PJ. 1989. The cDNA and derived amino acid sequence for human osteopontin. Nucleic Acids Res 17:3306.
16. Kinebuchi M, Ide T, Lupin D, Tamatani T, Miyasaka M, Matsuura A, Nagai Y, Kikuchi K, Uede T. 1991. A novel cell surface antigen involved in thymocyte and thymic epithelial cell adhesion. J Immunol 146:3721-3728.
17. Kinjo M, Oka K, Naito S, Kohga S, Tanaka K, Oboshi S, Hayata Y, Yasumoto K. 1979. Thromboplastic and fibrolytic activities of cultured human cencer cell lines. Br J Cancer 39:15-23.
18. Komatsubara S. 1978. Establishment of a new cell line (NRC-12) derived from a human renal cell carcinoma and its characteristics. Nippon Hinyokika Gakkai Zasshi 69:1535-1542.
19. Krakauer T. 1998. Variability in the sensitivity of nine enzyme-linked immunosorbant assays (ELISAs) in the measurement of human interlukin 6. J Immunol 219: 161-167.
20. Lan HY, Yu X-Q, Yang N, Nikolic-Paterson DJ, Mu W, Pichler R, Johnson RJ, Atkins RC. 1998. De novo glomerular osteopontin expression in rat crescentic glomerulonephritis. Kidney Int 53:136-145.
21. Liaw L, Skinner MP, Ranies EW, Ross R, Cheresh DA, Schwartz SM, Giachelli CM. 1995. The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins: role of αvβ3 in smooth muscle migration to osteopontin in vitro. J Clin Invest 95:713-724.
22. Min W, Shiraga H, Chalko C, Goldfarb S, Krishina GG, Hoyer JR. 1998. Quantitative studies of human urinary excretion of uropontin. Kidney Int 53:189-193.
23. Mori M, Yamaguchi K, Honda S, Nagasaki K, Ueda M, Abe O, Abe K. 1991. Cancer cachexia syndrome developed in nude mice bearing melanoma cells producing leukemiainhibitory factor. Cancer Res 51:6656-6659.
24. Nau GJ, Guilfoile P, Chupp GL, Berman JS, Kim SJ, Kornfeld H, Young RA. 1997. A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis. Proc Natl Acad Sci USA 94:6414-6419.
25. Dates AJ, Barraclough R, Rudland PS. 1996. The identification of osteopontin as a metastasis-related gene product in a rodent mammary tumour model. Oncogene 13: 97-104.
26. Dates AJ, Barraclough R, Rudland PS. 1997. The role of osteopontin in tumorigenesis and metastasis. Invasion Metastasis 17:1-15.
27. O'Brien ER, Garvin MR, Stewart DK, Hirohara T, Simpson JB, Schwartz SM, Giachelli CM. 1994. Osteopontin is synthesized by macrophages, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques. Arterioscler Thromb 14:1648-1656.
28. Okada Y, Kimura T, Kameoka M, Kishi M, Azuma I, Ikuta K. 1995. Viral activation from latency during retrodifferentiation of U937 cells exposed to phorbol ester followed by infection with human immunodeficiency virus type 1. Immunopharmacology 30:27-39.
29. Patarca R, Saavedra RA, Cantor H. 1993. Molecular and cellular basis of genetic resistance to bacterial infection: the role of the early T lymphocyte activation-1/ osteopontin gene. Crit Rev Immunol 13:225-246.
30. Saavedra RA. 1994. The roles of autophosphorylation and phosphorylation in the life of osteopontin. BioEssays 16: 913-918.
31. Saitoh Y, Kuratsu J, Takeshima H, Yamamoto S, Ushio Y. 1995. Expression of osteopontin in human glioma. Its correlation with the malignancy. Lab Invest 72:52-63.
32. Sekiya M, Adachi M, Hinoda Y, Imai K, Yachi A. 1994. Downregulation of Wilms' tumor gene (wt1) during myelomonocytic differentiation in HL60 cells. Blood 83: 1876-1882.
33. Senger DR, Perruzzi CA, Papadopoulos-Sergiou A, Van De Water L. 1994. Adhesive properties of osteopontin: regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain. Mol Biol Cell 5:565-574.
34. Singhal H, Bautista DS, Tonkin KS, O'Malley FP, Tuck AB, Chambers AF, Harris JF. 1997. Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival. Clin Cancer Res 3:605-611.
35. Smith LL, Cheung H-K, Ling LE, Chen J, Sheppard D, Pytela R, Giachelli CM. 1996. Osteopontin N-terminal domain contains a cryptic adhesive sequence recognized by α9β1 integrin. J Biol Chem 271:28485-28491.
36. Smith DB, Johnson KS. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40.
37. Sorensen ES, Hojrup P, Petersen TE. 1995. Posttranslational modifications of bovine osteopontin: identification of twenty-eight phosphorylation and three O-glycosylation sites. Protein Science 4:2040-2049.
38. Tuck AB, O'Malley FP, Singhal H, Tonkin KS, Harris JF, Bautista D, Chambers AF. 1997. Osteopontin (OPN) and p53 expression are associated with tumor progression in a case of synchronous, bilateral, invasive mammary carcinomas. Arch Pathol Lab Med 121:578-584.
39. Tuck AB, O'Malley FP, Singhal H, Harris JF, Tonkin KS, Kerkvliet N, Saad N, Doig GS, Chambers AF. 1998. Osteopontin expression in a group of lymph node negative breast cancer patients. Int J Cancer 79:502-508.
40. White DG, Hall JW, Brandli DW, Gehris AL, Bennett VD. 1996. Chick cartilage fibronectin differs in structure from the fibronectin in limb mesenchyme. Exp Cell Res 224:391-402.
41. Xuan JW, Hota C, Chambers AF. 1994. Recombinant GST-osteopontin fusion protein is functional in RGD-dependent cell adhesion. J Cell Biochem 54:247-255.
42. Young MF, Kerr JM, Termine JD, Wewer UM, Wang MG, McBride OW. 1990. cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human Osteopontin (OPN). Genomics 7:491-502.
43. Yue T-L, McKenna PJ, Ohlstein EH, Farach-Carson MC, Butler WT, Johanson K, McDevitt P, Feuerstein GZ, Stadel JM. 1994. Osteopontin-stimulated vascular smooth muscle migration is mediated by β3 integrin. Exp Cell Res 214:459-464.