Visualization of the in vivo generation of donor antigen-specific effector CD8+ T cells during mouse cardiac allograft rejection: In vivo effector CD8+ T cell generation during allograft rejection

Transplantation

Volumn 69, Issue 4, 2000, Pages 639-648

  Gilot, Bryant J ^b   Hara, Masaki ^b   Jones, Nick D ^b   Van Maurik, Andre ^b   Niimi, Masanori ^b   Hadjianastassiou, Vassilis ^b   Morris, Peter J ^b   Wood, Kathryn J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CD69 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; PADGEM PROTEIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL REGENERATION; CELL SIZE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; EFFECTOR CELL; GRAFT REJECTION; HEART TRANSPLANTATION; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0034011547     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200002270-00028     Document Type: Article

References (42)

1. Shirwan H, Chi D, Makowka L, Cramer DV. Lymphocytes infiltrating rat cardiac allografts express a limited repertoire of T cell receptor V beta genes. J Immunol 1993; 151: 5228.
2. Finn OJ, Miceli MC. Effector T-cell repertoire selection in human allograft rejection. Transplant Proc 1989; 21(1 Pt 1): 346.
3. Sherman LA. Dissection of the B10.D2 anti-H-2Kh cytolytic T lymphocyte receptor repertoire. J Exp Med 1980; 151: 1386.
4. Bill J, Yague J, Appel VB, et al. Molecular genetic analysis of 178 I-Abm12-reactive T cells. J Exp Med 1989; 169: 115.
5. Heelan BT. T cell receptor V-beta usage in allorecognition: a study of a mutant MHC class I antigen mismatch. Nuffield Department of Surgery. Oxford, United Kingdom: University of Oxford, 1995.
6. Rocha B, von Boehmer H. Peripheral selection of the T cell repertoire. Science 1991; 251: 1225.
7. Moskophidis D, Lechner F, Pircher H, Zinkernagel RM. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells [published erratum appears in Nature 1993 Jul 15;364(6434):262] [See comments]. Nature 1993; 362: 758.
8. Kearney ER, Pape KA, Loh DY, Jenkins MK. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1994; 1: 327.
9. Rosenberg AS, Singer A. Cellular basis of skin allograft rejection; an in vivo model of immune-mediated tissue destruction. Annu Rev Immunol 1992; 10: 333.
10. Mason DW, Morris PJ. Inhibition of the accumulation, in rat kidney allografts, of specific-but not nonspecific-cytotoxic cells by cyclosporine. Transplantation 1984; 37: 46.
11. Keene JA, Forman J. Helper activity is required for the in vivo generation of cytotoxic T lymphocytes. J Exp Med 1982; 155: 768.
12. Sponaas AM, Tomlinson PD, Schulz R, et al. Tolerance induction by elimination of subsets of self-reactive thymocytes. Int Immunol 1994; 6: 1593.
13. Hue I, Trucy J, McCoy C, Couez D, Malissen B, Malissen M. A novel type of aberrant T cell receptor alpha-chain gene rearrangement: implications for allelic exclusion and the V-J recombination process. J Immunol 1990; 144: 4410.
14. Albert F, Buferne M, Boyer C, Schmitt Verhulst AM. Interactions between MHC-encoded products and cloned T-cells. I. Fine specificity of induction of proliferation and lysis. Immunogenetics 1982; 16: 533.
15. Hua C, Boyer C, Buferne M, Schmitt Verhulst AM. Monoclonal antibodies against an H-2Kb-specific cytotoxic T cell clone detect several clone-specific molecules. J Immunol 1986; 136: 1937.
16. Gabert J, Langlet C, Zamoyska R, Parnes JR, Schmitt Verhulst AM, Malissen B. Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes. Cell 1987; 50: 545.
17. Bhattacharya A, Dorf ME, Springer TA. A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. J Immunol 1981; 127: 2488.
18. Qin S, Cobbold S, Tighe H, Benjamin R, Waldmann H. CD4 monoclonal antibody pairs for immunosuppression and tolerance induction. Eur J Immunol 1987; 17: 1159.
19. Pearson TC, Hamano K, Morris PJ, Wood KJ. Anti-CD4 monoclonal antibody-induced allograft survival is associated with a defect in interleukin-2-dependent T-cell activation. Transplant Proc 1993; 25(1 PART 1): 786.
20. Gallatin WM, Weissman IL, Butcher EC. A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature 1983; 304: 30.
21. Ortega G, Robb RJ, Shevach EM, Malek TR. The murine IL 2 receptor. I. Monoclonal antibodies that define distinct functional epitopes on activated T cells and react with activated B cells. J Immunol 1984; 133: 1970.
22. Lesley J, Schulte R, Trotter J, Hyman R. Qualitative and quantitative heterogeneity in Pgp-1 expression among murine thymocytes. Cell Immunol 1988; 112: 40.
23. Bottomly K, Luqman M, Greenbaum L, et al. A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines. Eur J Immunol 1989; 19: 617.
24. Yokoyama WM, Koning F, Kehn PJ, et al. Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J Immunol 1988; 141: 369.
25. Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol Rev 1992; 127: 5.
26. Cherwinski HM, Schumacher JH, Brown KD, Mosmann TR. Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. J Exp Med 1987; 166: 1229.
27. Ohara J, Paul WE. Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1. Nature 1985; 315: 333.
28. Sander B, Hoiden I, Andersson U, Moller E, Abrams JS. Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen: cytokine detection by immunoassay and intracellular immunostaining. J Immunol Methods 1993; 166: 201.
29. Ledbetter JA, Rouse RV, Micklem HS, Herzenberg LA. T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views. J Exp Med 1980; 152: 280.
30. Hardy RR, Carmack CE, Shinton SA, Kemp JD, Hayakawa K. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J Exp Med 1991; 173: 1213.
31. Prussin C, Metcalfe DD. Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. J Immunol Methods 1995; 188: 117.
32. Corry RJ, Winn HJ, Russell PS. Primarily vascularized allografts of hearts in mice: the role of H-2D, H-2K, and non-H-2 antigens in rejection. Transplantation 1973; 16: 343.
33. Superina RA, Peugh WN, Wood KJ, Morris PJ. Assessment of primarily vascularized cardiac allografts in mice. Transplantation 1986; 42: 226.
34. Wagoner LE, Zhao L, Bishop DK, Chan S, Xu S, Barry WH. Lysis of adult ventricular myocytes by cells infiltrating rejecting murine cardiac allografts. Circulation 1996; 93: 111.
35. Lyons AB, Parish CR. Determination of lymphocyte division by flow cytometry. J Immunol Methods 1994; 171: 131.
36. McHeyzer Williams MG, Altman JD, Davis MM. Tracking antigen-specific helper T cell responses. Curr Opin Immunol 1996; 8: 278.
37. Larsen CP, Steinman RM, Witmer Pack M, Hankins DF, Morris PJ, Austyn JM. Migration and maturation of Langerhans cells in skin transplants and explants. J Exp Med 1990; 172: 1483.
38. Iezzi G, Karjalainen K, Lanzavecchia A. The duration of antigenic stimulation determines the fate of naive and effector T cells. Immunity 1998; 8: 89.
39. Petschner F, Zimmerman C, Strasser A, Grillot D, Nunez G, Pircher H. Constitutive expression of Bcl-xL or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection. Eur J Immunol 1998; 28: 560.
40. Van Parijs L, Peterson DA, Abbas AK. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity 1998; 8: 265.
41. Reiner SL, Seder RA. T helper cell differentiation in immune response. Curr Opin Immunol 1995; 7: 360.
42. Seder RA, Paul WE. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu Rev Immunol 1994; 12: 635.