Melatonin and retinyl acetate as chemopreventives in DMBA-induced mammary carcinogenesis in female Sprague-Dawley rats

Folia Biologica

Volumn 46, Issue 2, 2000, Pages 69-72

  Ahlersova E ^a   Ahlers, I ^a   Kubatka, P ^a   Bojkova B ^a   Mocikova K ^a   Gajdosova S ^a   Onderkova H M ^a  

^a P J AFÁRIK UNIVERSITY   (Slovakia)

Author keywords

Melatonin; Rat mammary carcinogenesis; Retinyl acetate

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE; MELATONIN; RETINOL ACETATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; CANCER INCIDENCE; CANCER PREVENTION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; FEMALE; NONHUMAN; RAT; TUMOR VOLUME;

ANIMALIA;

EID: 0034010926     PISSN: 00155500     EISSN: 25337602     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Arendt, J. (1995) Melatonin and the Mammalian Pineal Gland, pp. 275-290. Chapman and Hall, London.
2. Baldwin, W. S., Barret J. C (1998) Melatonin does not inhibit estradiol-stimulated proliferation in MCF-7 and BG-1 cells. Carcinogenesis 19, 1895-1900.
3. Bartsch, H., Bartsch, C. (1994) Serial transplants of DMBA-induced mammary tumours in Fisher 344 rats. Effects of melatonin and pineal extracts on low and fast growing passages: in vivo and in vitro studies. Adv. Pineal Res. 8, 473-478.
4. Blask, D. E., Pelletier, D. B., Hill, S. M. (1991) Pineal melatonin inhibition of tumour promotion in the N-nitroso-N-methylurea model of mammary carcinogenesis: potential involvement of antiestrogenic mechanisms in vivo. J. Cancer Res. 117, 526-532.
5. Blask, D. E., Lemus-Wilson, A., Wilson, S. T. (1992) Breast cancer: a model system for studying the neuroendocrine role of pineal melatonin in oncology. Biochem. Soc. Transact. 20, 309-311.
6. Blask, D. E., Satter, L. A., Dauchy, R. T. (1997) Melatonin suppression of tumor growth in vivo: a novel mechanism involving inhibition of fatty acid uptake and metabolism. In: Therapeutic Potential of Melatonin, eds. Maestroni, G. J. M , Conti, A., Reiter, R. J., pp. 107-114, Karger, Basel.
7. Blask, D. E., Sauer, L. A., Dauchy, R. T., Holowachuk, E. W., Ruhoff, M. S. (1999) New actions of melatonin on tumor metabolism and growth. Biol. Signals Recept. 8, 49-55.
8. Bojková, B., Kubatka, P., Môcikova, K., Mníchová, M., Ahlersová, E., Ahlers, I. (2000) Effects of retinyl acetate and melatonin on N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats. Folia Biol. (Praha), 46, 73-76.
9. Coradini, B., Biffi A., Pellizaro, C., Pironello, E., DiFronzo, G. (1997) Combined effect of tamoxifen or interferon-ß and 4-hydroxyphenylretinamide on the growth of breast cancer cell lines. Tumor Biol. 18, 22-29.
10. Cos, S., Fernander, R., Guezmes, A., Sánchez-Barceló, E. J. (1998) Influence of melatonin on invasive and metastatic properties of MCF-7 human breast cancer cell lines. Cancer Res. 58, 4383-4390.
11. El-Bayoumy, K. (1994) Evaluation of chemopreventive agents against breast cancer and proposed strategies for future clinical intervention trials. Carcinogenesis 15, 2395-2420.
12. Evans, T. R., Kaye, S. B. (1999) Retinoids: present role and future potential. Br. J. Cancer 80, 1-8.
13. Gerster, H. (1993) Anticarcinogenic effect of common carotenoids. Int. J. Vitam. Nutr. Res. 63, 93-121.
14. Hill, S. M., Blask, D. E. (1988) Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture. Cancer Res. 48, 6121-6126.
15. Hill, D. L., Grubbs, C. J. (1992) Retinoids and cancer prevention. Annu Rev. Nutr. 12, 161-181.
16. Kelloff, G. J., Hawk, T., Karp, J. E., Crowell, J. A., Boone, Ch. W., Steele, V. E., Lubet, R. A., Sigman, C. C. (1997) Progress in clinical chemoprevention. Semin. Oncol. 24, 241-252.
17. Kothari, L. S. (1987) Influence of chronic melatonin on 9,10-dimethyl-1,2-benzanthracene induced mammary tumors in female Holtzman rats exposed to continuous light. Oncology 44, 64-66.
18. Moon, R. C., Grubbs, C J., Sporn, M. B. (1976) Inhibition of 7,12-dimetylbenz(a)anthracene-induced mammary carcinogenesis by retinyl acetate. Cancer Res. 36, 2626-2630.
19. Moon, R. C., Sporn M. B., Goodman, D. G. (1977) Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-N-nitrosourea. Nature 267, 620-621.
20. Moon, R. C., McCormick, D. L., Mehta, R. G. (1983) Inhibition of carcinogenesis by retinoids. Cancer Res. 43, 2469-2475.
21. Moon, R. C., Mehta, R. G., Detrisac, C. J. (1992) Retinoids as chemopreventive agents for breast cancer. Cancer Detect. Prev. 16, 73-80.
22. Moon, R. C., Kelloff, G. J., Detrisac, C. J., Steele, V. E., Thomas, C., Sigman, C. C. (1992) Chemoprevention of NMU-induced mammary tumors in the mature rat by 4-HPR and tamoxifen. Anticancer Res. 12, 1147-1154.
23. Noguchi, M., Rose, D. P., Miyazaki, I. (1996) Breast cancer chemoprevention: clinical trials and research. Oncology 53, 175-181.
24. Panzer, A., Viljoen, M. (1997) The validity of melatonin as an oncostatic agent. J. Pineal Res. 22, 184-202.
25. Papazisis, K. T., Kouretas, D., Geromichalos, G. D., Sivridis, E., Tsekreli, O. K., Dimitriadis, K. A., Kortsaris, A. H. (1998) Effects of melatonin on proliferation of cancer cell lines. J. Pineal Res. 25, 211-218.
26. Rao, A. R., Hussain, S. P., Jannu, L. N., Kumari, M. V., Aradhana, L. (1990) Modulatory influences of tamoxifen, tocopherol, retinyl-acetate, aminoglutethimide, ergocryptine and selenium on DMBA-induced initiation of mammary carcinogenesis in rats. Indian J. Exp. Biol. 28, 409-416.
27. Reiter, R. J. (1995) Functional pleiotropy of the neurohormone melatonin: antioxidant protection and neuroendocrine regulation. Front. Neuroendocrinol. 16, 383-415.
28. Subramanian, A., Kothari, L. (1991) Suppressive effect by melatonin on different phases of 9,10-dimethyl-1,2-benzanthracene (DMBA)-induced rat mammary gland carcinogenesis. Anticancer Drugs 2, 297-303.
29. Tamarkin, L., Cohen, M., Roselle, D. (1981) Melatonin inhibition and pinealectomy enhancement of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats. Cancer Res. 41, 4432-4436.
30. Widschwendter, M., Berger, J., Daxenbichler, G., Müller-Holzner, E., Widschwendter, A., Mayr, A., Marth, Ch., Zeimet, A. G. (1997) Loss of retinoic acid receptor ß expression in breast cancer and morphologically normal adjacent tissue but not in the normal breast tissue distant from the cancer. Cancer Res. 57, 4158-4161.