Different mechanisms mediate β adrenoceptor stimulated vasorelaxation of coronary and femoral arteries

Acta Pharmacologica Sinica

Volumn 21, Issue 4, 2000, Pages 309-312

  Xu, Biao ^a   Huang, Yu ^a  

^a Department of General Surgery   (China)

Author keywords

Adrenergic beta receptors; Coronary artery; Femoral artery; Nitric oxide; Vascular endothelium

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; ISOPRENALINE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL TISSUE; ARTERY DILATATION; ARTICLE; BETA ADRENERGIC STIMULATION; CONCENTRATION RESPONSE; CORONARY ARTERY; DRUG EFFECT; ENZYME INHIBITION; FEMALE; FEMORAL ARTERY; MALE; NONHUMAN; SWINE; VASCULAR ENDOTHELIUM;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ARTERIES; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; FEMALE; FEMORAL ARTERY; IMIDAZOLES; ISOPROTERENOL; MALE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; OMEGA-N-METHYLARGININE; PROPANOLAMINES; SWINE; VASODILATION;

EID: 0034009381     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Kuriyama H, Ito Y, Suzuki H, Kitamura K, Itoh T. Factors modifying contraction-relaxation cycle in vascular smooth muscles. Am J Physiol 1982; 243: H641-2.
2. Howell RE, Albeda SM, Daise ML, Levine EM. Characterization of β adrenergic receptors in cultured human and bovine endothelial cells. J Appl Physiol 1988; 65: 1251-7.
3. Molenaar P, Malta E, Jones CR, Buxton BF, Summers RJ. Autoradiographic localization and function of β adrenoceptors on the human internal mammary artery and saphenous vein. Br J Pharmacol 1988; 95: 225-33.
4. Xu B, Queen LR, Ferro A. β-Adrenoceptor-mediated vasorelaxation is largely mediated through the L-arginine/nitric oxide system in human umbilical vein. J Physiol (Lond) 1998; 506: P30-1.
5. Graves J, Poston L. β-Adrenoceptor agonist mediated relax-ation of rat isolated resistance arteries: a role for the endothelium and nitric oxide. Br J Pharmacol 1993; 103: 631-7.
6. Blankesteijn WM, Thien T. Effect of NG-monomethyl-L-arginine on the β-adrenoceptor- mediated relaxation of rat mesenteric resistance arteries. Life Sci 1993; 52: PL135-9.
7. MacDonald PS, Dubbin PM, Dusting GJ. β-Adrenoceptors on endothelial cells do not influence release of relaxing factor in dog coronary arteries. Clin Exp Pharmacol 1987; 14: 525-34.
8. Bea ML, Ghaleh B, Giudicelli JF, Berdeaux A. Lack of importance of NO in β-adrenoceptor-mediated relaxation of large epicardial canine coronary arteries. Br J Pharmacol 1994; 111: 981-2.
9. 2 adrenoceptors activated by (-) adrenaline in the rat sino-atrial node. Naunyn Schmiedeberg's Arch Pharmacol 1986; 333: 73-6.
10. 3H-ICI 118551 and blocking potency of ICI 118551. Naunyn Schmiedeberg's Arch Pharmacol 1985; 331: 40-51.
11. Dawes M, Chowienczyk PJ, Ritter JM. Effects of inhibition of the L-arginine/nitric oxide pathway on vasodilation caused by β-adrenergic agonists in human forearm. Circulation 1997; 95: 2293-7.
12. 2 adrenoceptors in human umbilical vein endothelium in vitro. Br J Pharmacol 1999; 126: 1872-80.