Inhaled carbon monoxide does not cause pulmonary vasodilation in the late-gestation fetal lamb

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 278, Issue 4 22-4, 2000, Pages

  Grover, Theresa R ^a,b   Rairigh, Robyn L ^a   Zenge, Jeanne P ^a   Abman, Steven H ^a   Kinsella, John P ^a  

^a Children's Hospital Colorado   (United States)

^b NONE   (United States)

Author keywords

Heme oxygenase; Nitric oxide; Persistent pulmonary hypertension of the newborn; Pulmonary hypertension

Indexed keywords

CARBON MONOXIDE; GUANYLATE CYCLASE; PROTOPORPHYRIN ZINC;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; BLOOD VESSEL TONE; DUCTUS ARTERIOSUS; FETUS; HYPOTHESIS; HYPOXIA; LUNG BLOOD FLOW; NONHUMAN; PREGNANCY; PRESSURE GRADIENT; PRESSURE TRANSDUCER; PRIORITY JOURNAL; SHEAR STRESS; VASODILATATION;

EID: 0034008783     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.278.4.l779     Document Type: Article

References (38)

1. Abman SH, Chatfield BA, Hall SL, and McMurtry IF. Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth. Am J Physiol Heart Circ Physiol 259: H1921-H1927, 1990.
2. Anderson KE, Simionatto CS, Drummond GS, and Kappas A. Disposition of tin-protoporphyrin and suppression of hyperbilirubinemia in humans. Clin Pharmacol Ther 39: 510-520, 1986
3. Brune B and Ullrich V. Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol Pharmacol 32: 497-504, 1987.
4. Burstyn J, Yu AE, and Dierks EA. Studies of heme coordination and ligand binding properties of soluble guanylate cyclase (sGC): characterization of Fe(II)sGC and Fe(II)sGC(CO) by electronic absorption and magnetic circular dichroism spectroscopies and failure of CO to activate the enzyme. Biochemistry 34: 5896-5903, 1995.
5. Caudill TK, Resta TC, Kanagy NL, and Walker BR. Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia. Am J Physiol Regulatory Integrative Comp Physiol 275: R1025-R1030, 1998.
6. Choi AMK and Alam J. Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am J Respir Cell Mol Biol 15: 9-19, 1996.
7. Christodoulides N, Durante W, Kroll MH, and Schafer AI. Vascular smooth muscle cell heme oxygenases generate guanyl cyclase-stimulatory carbon monoxide. Circulation 91: 2306-2309, 1995.
8. Coceani F. Control of the ductus arteriosus - a new function for cytochrome P450, endothelin and nitric oxide. Biochem Pharmacol 48: 1315-1318, 1994.
9. 450-linked monooxygenase: involvement in the lamb ductus arteriosus. Am J Physiol Heart Circ Physiol 246: H640-H643, 1984.
10. Coceani F, Kelsey L, and Seidlitz E. Carbon monoxide-induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylate cyclase. Br J Pharmacol 118: 1689-1696, 1996.
11. Coceani F, Kelsey L, Seidlitz E, Marks GS, McLaughlin BE, Vreman HJ, Stevenson DK, Rabinovitch M, and Ackerley C. Carbon monoxide formation in the ductus arteriosus in the lamb: implications for the regulation of muscle tone. Br J Pharmacol 120: 599-608, 1997.
12. Durante W, Christodoulides N, Cheng K, Peyton KJ, Sunahara RK, and Schafer AI. cAMP induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle. Am J Physiol Heart Circ Physiol 273: H317-H323, 1997.
13. Faraci FM and Brian JE Jr. Nitric oxide and the cerebral circulation. Stroke 25: 692-703, 1994.
14. Fox JJ, Ziegler JW, Ivy DD, Halbower AC, Kinsella JP, and Abman SH. Role of nitric oxide and cGMP system in regulation of ductus arteriosus tone in ovine fetus. Am J Physiol Heart Circ Physiol 271: H2638-H2645, 1996.
15. Grozdanovic Z and Gossrau R. Expression of heme oxygenase-2 (HO-2)-like immunoreactivity in rat tissue. Acta Histochem 98: 203-214, 1996.
16. Ivy DD, Parker TA, Ziegler JW, Galan HL, Kinsella JP, Tuder RM, and Abman SH. Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus. J Clin Invest 99: 1179-1186, 1997.
17. Johnson RA, Lavesa M, Askari B, Abraham NG, and Nasjletti A. A heme oxygenase product, presumably carbon monoxide, mediates a vasodepressor function in rats. Hypertension 25: 166-169, 1995.
18. Kappas A, Drummond GS, Manola T, Permezaki S, and Valaes T. Sn-protoporphyrin use in the management of hyperbilirubinemia in term newborns with direct Coombs-positive ABO incompatibility. Pediatrics 81: 485-497, 1988.
19. Kinsella JP, McQueston JA, Rosenberg AA, and Abman SH. Hemodynamic effects of exogenous nitric oxide in ovine transitional pulmonary circulation. Am J Physiol Heart Circ Physiol 262: H875-H880, 1992.
20. Lee PJ, Alam J, Wiegand GW, and Choi AMK. Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury. Am J Respir Cell Mol Biol 14: 556-568, 1996.
21. Lee PJ, Jiang B-H, Chin BY, Iyer NV, Alam J, Semenza GL, and Choi AMK. Hypoxia inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J Biol Chem 272: 5375-5381, 1997.
22. Lewis AB, Heymann MA, and Rudolph AM. Gestational changes in pulmonary vascular responses in fetal lambs in utero. Circ Res 39: 536-541, 1976.
23. Maines MD. Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 2: 2557-2568, 1988.
24. Maines MD. The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol 37: 517-554, 1997.
25. Mansouri A and Perry CA. Alteration of platelet aggregation by cigarette smoke and carbon monoxide. Thromb Haemost 48: 286-288, 1982.
26. Marks GS, Brien JF, Nakatsu K, and McLaughlin BE. Does carbon monoxide have a physiological function? Trends Pharmacol Sci 12: 185-188, 1991.
27. Morita T, Perrella MA, Lee ME, and Kourembanas S. Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc Natl Acad Sci USA 92: 1475-1479, 1995.
28. Ramos KS, Lin H, and McGrath JJ. Modulation of cyclic guanosine monophosphate levels in cultured aortic smooth muscle cells by carbon monoxide. Biochem Pharmacol 38: 1368-1370, 1989.
29. Schacter BA. Heme catabolism by heme oxygenase: physiology, regulation, and mechanism of action. Semin Hematol 25: 349-369, 1988.
30. Stone JR and Marietta MA. Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states. Biochemistry 33: 5636-5640, 1994.
31. Sylvester JT and McGowan C. The effects of agents that bind cytochrome P-450 on hypoxic pulmonary vasoconstriction. Circ Res 43: 429-437, 1978.
32. Tenhunen R, Marver HS, and Schmid R. Microsomal heme oxygenase. Characterization of the enzyme. J Biol Chem 244: 6388-6394, 1969.
33. Utz J and Ullrich V. Carbon monoxide relaxes ileal smooth muscle through activation of guanylate cyclase. Biochem Pharmacol 41: 1195-2001, 1991.
34. Valaes T, Petmezaki S, Henschke C, Drummond GS, and Kappas A. Control of jaundice in preterm newborns by an inhibitor of bilirubin production: studies with tin-mesoporphyrin. Pediatrics 93: 1-11, 1994.
35. Vedernikov YP, Graser T, and Vanin AF. Similar endothelium-independent arterial relaxation by carbon monoxide and nitric oxide. Biomed Biochim Acta 48: 601-603, 1989.
36. Vreman HJ, Ekstrand BC, and Stevenson DK. Selection of metalloporphyrin heme oxygenase inhibitors based on potency and photoreactivity. Pediatr Res 33: 195-200, 1993.
37. Weiss G, Werner-Felmayer G, Werner ER, Grunewald K, Wachter H, and Hentze MW. Iron regulates NO synthase activity by controlling nuclear transcription. J Exp Med 180: 969-976, 1994.
38. Yet S-F, Perrella M, Layne MD, Hsieh C-M, Maemura K, Kobzik L, Wiesel P, Christou H, Kourembanas S, and Lee M-E. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice. J Clin Invest 103: R23-R29, 1999.