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Volumn 6, Issue 4, 2000, Pages 1342-1346

Altered pharmacokinetics and metabolism of CPT-11 in liver dysfunction: A need for guidelines

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; FLUOROURACIL; IRINOTECAN; TUMOR VACCINE; UFT;

EID: 0034006699     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (25)

References (18)
  • 1
    • 0027972726 scopus 로고
    • Topoisomerase I inhibitors. Topotecan and irinotecan
    • Creamers, G. J., Lund, B., and Verweij, J. Topoisomerase I inhibitors. Topotecan and irinotecan. Cancer Treat. Rev., 20: 73-96, 1994.
    • (1994) Cancer Treat. Rev. , vol.20 , pp. 73-96
    • Creamers, G.J.1    Lund, B.2    Verweij, J.3
  • 6
    • 0025996996 scopus 로고
    • Intracellular roles of SN-38, a metabolite of camptothecin derivative CPT-11, in the antitumor effect of CPT-11
    • Kawato, Y., Aonuma, M., Hirota, Y., Kuga, H., and Sato, K. Intracellular roles of SN-38, a metabolite of camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res., 51: 4187-419, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 4187-4419
    • Kawato, Y.1    Aonuma, M.2    Hirota, Y.3    Kuga, H.4    Sato, K.5
  • 7
    • 0028022585 scopus 로고
    • Metabolic fate of irinotecan in humans: Correlation of glucuronidation with diarrhea
    • Gupta, E., Lestingi, T. M., Mick, R., Ramirez, J., Vokes, E. E., and Ratain, M. J. Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea. Cancer Res., 54: 3723-3725, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3723-3725
    • Gupta, E.1    Lestingi, T.M.2    Mick, R.3    Ramirez, J.4    Vokes, E.E.5    Ratain, M.J.6
  • 8
    • 0031714683 scopus 로고    scopus 로고
    • Clinical pharmacology of camptothecins
    • Iyer, L., and Ratain, M. J. Clinical pharmacology of camptothecins. Cancer Chemother. Pharmacol., 42: 531-543, 1998.
    • (1998) Cancer Chemother. Pharmacol. , vol.42 , pp. 531-543
    • Iyer, L.1    Ratain, M.J.2
  • 12
    • 0027937924 scopus 로고
    • Reversed-phase high-performance liquid chromatographic method for the quantitation of the carboxylate and lactone forms of the camptothecin derivative irinotecan, CPT-11, and its metabolite SN-38 in plasma
    • Rivory, L. P., and Robert, J. Reversed-phase high-performance liquid chromatographic method for the quantitation of the carboxylate and lactone forms of the camptothecin derivative irinotecan, CPT-11, and its metabolite SN-38 in plasma. J. Chromatogr. B Biomed. Appl., 661: 133-141, 1994.
    • (1994) J. Chromatogr. B Biomed. Appl. , vol.661 , pp. 133-141
    • Rivory, L.P.1    Robert, J.2
  • 13
    • 0028989171 scopus 로고
    • Identification and kinetics of a 3-glucuronide of SN-38 in human plasma after administration of the camptothecin derivative irinotecan (CPT-11)
    • Rivory, L. P., and Robert, J. Identification and kinetics of a (3-glucuronide of SN-38 in human plasma after administration of the camptothecin derivative irinotecan (CPT-11). Cancer Chemother. Pharmacol., 36: 176-179, 1995.
    • (1995) Cancer Chemother. Pharmacol. , vol.36 , pp. 176-179
    • Rivory, L.P.1    Robert, J.2
  • 14
  • 16
    • 0028022585 scopus 로고
    • Metabolic fate of irinotecan in humans: Correlation of glucuronidation with diarrhea
    • Gupta, E., Lestingi, T. M., Mick, R., Ramirez, J., Vokes, E. E., and Ratain, M. J. Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea. Cancer Res., 54: 3723-3725, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3723-3725
    • Gupta, E.1    Lestingi, T.M.2    Mick, R.3    Ramirez, J.4    Vokes, E.E.5    Ratain, M.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.