Advanced glycation end products: A nephrologist's perspective

American Journal of Kidney Diseases

Volumn 35, Issue 3, 2000, Pages 365-380

[No Author Info available]

Author keywords

Advanced glycation end products (AGEs); Aging; Aminoguanidine (AGN); Diabetes; Dialysis; Oxidant stress; Renal failure

Indexed keywords

AMINOGUANIDINE; BETA 2 MICROGLOBULIN; TOXIN;

AGING; ATHEROSCLEROSIS; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; GLYCATION; KIDNEY FAILURE; KIDNEY FUNCTION; REVIEW; UREMIA; URINARY EXCRETION;

EID: 0034003453     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0272-6386(00)70189-2     Document Type: Article

References (146)

1. LC Maillard Action des acides amines sur les sucres: Formation des melanoiddines par voie methodique C R Acad Sci 154 1912 66
2. M Brownlee Lilly Lecture 1993. Glycation and diabetic complications Diabetes 43 1994 836 841
3. AA Booth RG Khalifah P Todd BG Hudson In vitro kinetic studies of formation of antigenic advanced glycation end products (AGEs). Novel inhibition of post-Amadori glycation pathways J Biol Chem 272 1997 5430 5437
4. VM Monnier DR Sell RH Nagaraj S Miyata S Grandhee P Odetti SA Ibrahim Maillard reaction–mediated molecular damage to extracellular matrix and other tissue proteins in diabetes, aging, and uremia Diabetes 41 suppl 2 1992 S36 S41
5. JA Dunn JS Patrick SR Thorpe JWA Baynes Oxidation of glycated proteins: Age-dependent accumulation of N -(carboxy-methyl)lysinein lens proteins Biochemistry 28 1989 9464 9468
6. Z Makita H Vlassara EJ Rayfield K Cartwright EA Friedman R Rodby A Cerami R Bucala Hemoglobin-AGE: A circulating marker of advanced glycosylation Science 258 1992 651 653
7. 2 -microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis J Clin Invest 92 1993 1243 1252
8. MA Smith S Taneda PL Richey S Miyata SD Yan D Stern LM Sayre VM Monnier G Perry Advanced Maillard reaction end products are associated with Alzheimer disease pathology Proc Natl Acad Sci U S A 91 1994 5710 5714
9. R Dolhofer-Bliesener B Lechner R Deppisch E Ritz KD Gerbitz Immunological determination of advanced glycosylation end-products in human blood and urine Nephrol Dial Transplant 10 1995 657 664
10. T Miyata Y Ueda K Horie M Nangaku S Tanaka C van Ypersele de Strihou K Kurokawa Renal catabolism of advanced glycation end products: The fate of pentosidine Kidney Int 53 1998 416 422
11. MJC Kent ND Light AJ Bailey Evidence for glucose-mediated covalent cross-linking after glycosylation in vitro Biochem J 225 1985 745 752
12. MX Fu KJ Wells-Knecht JA Blackledge TJ Lyons SR Thorpe JW Baynes Glycation, glycoxidation, and cross-linking of collagen by glucose. Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction Diabetes 43 1994 676 683
13. J Brett AM Schmidt SD Yan YS Zou E Weidman M Neeper C Przysiecki A Shaw A Migheli D Stern Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues Am J Pathol 143 1993 1699 1712
14. H Vlassara Protein glycation in the kidney: Role in diabetes and aging Kidney Int 49 1996 1795 1804
15. R Bucala H Vlassara Advanced glycosylation end products in diabetic renal and vascular disease Am J Kidney Dis 26 1995 875 888
16. H Vlassara Recent progress on the biologic and clinical significance of advanced glycosylation end products J Lab Clin Med 124 1994 19 30
17. M Brownlee H Vlassara A Cerami Nonenzymatic glycosylation and the pathogenesis of diabetic complications Ann Intern Med 101 1984 527 537
18. JA Dunn MU Ahmed MMN Murtiashaw JM Richardson MD Walla JW Baynes Reaction of ascorbate with lysine and protein under autoxidizing conditions: Formation of N -(carboxy-methyl) lysine by reaction between lysine and products of autoxidation of ascorbate Biochemistry 29 1990 10964 10970
19. T Miyata Y Wada Z Cai Y Iida K Horie Y Yasuda K Maeda K Kurokawa C van Ypersele de Strihou Implication of an increased oxidative stress in the formation of advanced glycation end products in patients with end-stage renal failure Kidney Int 51 1997 1170
20. MP Cohen FN Ziyadeh Role of Amadori-modified nonenzymatically glycated serum proteins in the pathogenesis of diabetic nephropathy J Am Soc Nephrol 7 1996 183 190
21. R Dolhofer-Bliesener B Lechner KD Gerbitz Possible significance of advanced glycation end products in serum in end-stage renal disease and in late complications of diabetes Eur J Clin Chem Clin Biochem 34 1996 355 361
22. E Ritz R Deppisch P Nawroth Toxicity of uremia—Does it come of age? Nephrol Dial Transplant 9 1994 1 2
23. DC Muller D Elahi JD Tobin R Andres The effect of age on insulin resistance and secretion: A review Semin Nephrol 16 1996 289 298
24. HJ Androgue Glucose homeostasis and the kidney Kidney Int 42 1992 1266 1282
25. MP Vitek K Bhattacharya JM Glendening E Stopa H Vlassara R Bucala K Manogue A Cerami Advanced glycation end products contribute to amyloidosis in Alzheimer disease Proc Natl Acad Sci U S A 91 1994 4766 4770
26. E Schleicher OH Wieland Protein glycation: Measurement and clinical relevance J Clin Invest 27 1989 577 587
27. S Radoff Z Makita H Vlassara A radio-receptor assay for advanced glycosylation end products Diabetes 40 1991 1731 1738
28. T Mitsuhashi H Vlassara HW Founds YM Li Standardizing the immunological measurement of advanced glycation end products using normal human serum J Immunol Methods 207 1997 79 88
29. Z Makita R Bucala EJ Rayfield EA Friedman AM Kaufman SM Korbet RH Barth JA Winston H Fuh KR Manogue R Kirk A Cerami H Vlassara Reactive glycosylation end products in diabetic uremia and treatment of renal failure Lancet 343 1994 1519 1522
30. P Papanastasiou L Grass H Rodela A Patrikarea D Oreopoulos EP Diamandis Immunological quantification of advanced glycosylation end products in the serum of patients on hemodialysis or CAPD Kidney Int 46 1994 216 222
31. H Vlassara Serum advanced glycosylation end products: A new class of uremic toxin? Blood Purif 12 1994 54 59
32. Z Makita S Radoff EJ Rayfield Z Yang EY Skolnik V Delaney EA Friedman A Cerami H Vlassara Advanced glycosylation end products in patients with diabetic nephropathy N Engl J Med 331 1991 325 336
33. F Hayase RH Nagaraj S Miyata FG Njoroge VM Monnier Aging of proteins: Immunological detection of a glucose-derived pyrrole formed during Maillard reaction in vivo J Biol Chem 264 1989 3758 3764
34. DR Sell VM Monnier End-stage renal disease and diabetes catalyze the formation of a pentose-derived cross-link from aging human collagen J Clin Invest 85 1990 380 384
35. T Niwa T Katsuzaki Y Ishizaki F Hayase T Miyazaki T Uematsu N Tatemichi Y Takei Imidazolone, a novel advanced glycation end product, is present at high levels in kidneys of rats with streptozotocin-induced diabetes FEBS Lett 407 1997 297 302
36. K Ienaga K Nakamura T Hochi Y Nakazawa Y Fukunaga H Kakita K Nakano Crosslines, fluorophores in the AGE-related cross-linked proteins Contrib Nephrol 112 1995 42 51
37. DR Sell Ageing promotes the increase of early glycation Amadori product as assessed by epsilon- N -(2-furoylmethyl)-L -lysine (furosine) levels in rodent skin collagen. The relationship to dietary restriction and glycoxidation Mech Ageing Dev 95 1997 81 99
38. DR Sell A Lapolla P Odetti J Fogarty VM Monnier Pentosidine formation in skin correlates with severity of complications in individuals with long-standing IDDM Diabetes 41 1992 1286 1292
39. MU Ahmed SR Thorpe JW Baynes Identification of carboxy-methyllysine as a degradation product of fructosyllysine in glycated proteins J Biol Chem 261 1986 4889 4894
40. MU Ahmed JA Dunn MD Walla SR Thorpe JW Baynes Oxidative degradation of glucose adducts to protein J Biol Chem 263 1988 8816 8821
41. A Bierhaus MA Hofmann R Ziegler PP Nawroth AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept Cardiovasc Res 37 1998 586 600
42. TJ Berg K Dahl-Jorgensen PA Torjesen KF Hanssen Increased serum levels of advanced glycation end products (AGEs) in children and adolescents with IDDM Diabetes Care 20 1997 1006 1008
43. JL Wautier C Zoukourian O Chappey MP Wautier PJ Guillausseau R Cao O Hori D Stern AM Schmidt Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats J Clin Invest 97 1996 238 243
44. AM Schmidt SD Yan J Brett R Mora R Nowygrod D Stern Regulation of human mononuclear phagocyte migration by cell-surface-binding proteins for advanced glycation end products J Clin Invest 91 1993 2155 2168
45. EY Skolnik SZ Yang Z Makita S Radoff M Kirstein H Vlassara Human and rat mesangial cell receptors for glucose-modified proteins: Potential role in kidney tissue remodeling and diabetic nephropathy J Exp Med 174 1991 931 939
46. H Vlassara YM Li F Imani D Wojciechowicz Z Yang FT Liu A Cerami Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): A new member of the AGE-receptor complex Mol Med 1 1995 634 646
47. SD Yan D Stern AM Schmidt What's the RAGE? The receptor for advanced glycation end products (RAGE) and the dark side of glucose Eur J Clin Invest 27 1997 179 181
48. M Abel U Ritthaler Y Zhang Y Deng AM Schmidt J Greten T Sernau P Wahl K Andrassy E Ritz Expression of receptors for advanced glycosylated end-products in renal disease Nephrol Dial Transplant 10 1995 1662 1667
49. H Vlassara Protein glycation in the kidney: Role in diabetes and aging Kidney Int 49 1996 1795 1804
50. TJ Lyons Glycation and oxidation: A role in the pathogenesis of atherosclerosis Am J Cardiol 71 1993 26B 31B
51. F Imani Y Horii M Suthanthiran EY Skolnik Z Makita V Sharma P Sehajpal H Vlassara Advanced glycosylation end product–specific receptors on human and rat T-lymphocytes mediate synthesis of interferon gamma: Role in tissue remodeling J Exp Med 178 1993 2165 2172
52. M Hangaishi J Taguchi T Miyata Y Ikari M Togo Y Hashimoto T Watanabe S Kimura K Kurokawa M Ohno Increased aggregation of human platelets produced by advanced glycation end products in vitro Biochem Biophys Res Commun 248 1998 285 292
53. G Hasegawa K Nakano M Sawada K Uno Y Shibayama K Ienaga M Kondo Possible role of tumor necrosis factor and interleukin-1 in the development of diabetic nephropathy Kidney Int 40 1991 1007 1012
54. CW Yang H Vlassara EP Peten CJ He GE Striker LJ Striker Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease Proc Natl Acad Sci U S A 91 1994 9436 9440
55. DC Throckmorton AP Brogden B Min H Rasmussen M Kashgarian PDGF and TGF-beta mediate collagen production by mesangial cells exposed to advanced glycosylation end products Kidney Int 48 1995 111 117
56. MP Cohen FN Ziyadeh Amadori glucose adducts modulate mesangial cell growth and collagen gene expression Kidney Int 45 1994 475 484
57. O Chappey C Dosquet MP Wautier JL Wautier Advanced glycation end products, oxidant stress and vascular lesions Eur J Clin Invest 27 1997 97 108
58. R Bucala K Tracey A Cerami Advanced glycosylation products quench nitric oxide and mediate the defective endothelium-dependent vasodilatation in experimental diabetes J Clin Invest 87 1991 432 438
59. RK Studer FR DeRubertis PA Craven Nitric oxide suppresses increase in mesangial cell protein kinase C, transforming growth factor β, and fibonectin synthesis induced by thromboxane J Am Soc Nephrol 7 1996 999 1005
60. H Vlassara H Fuh Z Makita S Krungkrai A Cerami R Bucala Exogenous advanced glycosylation end products induce complex vascular dysfunction in normal animals: A model for diabetic and aging complications Proc Natl Acad Sci U S A 89 1992 12043 12047
61. Y Nakamura Y Horii T Nishino H Shiiki Y Sakaguchi T Kagoshima K Dohi Z Makita H Vlassara R Bucala Immunohistochemical localization of advanced glycosylation end products in coronary atheroma and cardiac tissue in diabetes mellitus Am J Pathol 143 1993 1649 1656
62. W Palinski T Koschinsky SW Butler E Miller H Vlassara A Cerami JL Witztum Immunological evidence for the presence of advanced glycosylation end products in atherosclerotic lesions of euglycemic rabbits Arterioscler Thromb Vasc Biol 15 1995 571 582
63. C Cerami H Founds I Nicholl T Mitsuhashi D Giordano S Vanpatten A Lee Y Al-Abed H Vlassara R Bucala A Cerami Tobacco smoke is a source of toxic reactive glycation products Proc Natl Acad Sci U S A 94 1997 13915 13920
64. R Bucala Z Makita G Vega S Grundy T Koschinsky A Cerami H Vlassara Modification of low-density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency Proc Natl Acad Sci U S A 91 1994 9441 9445
65. The Diabetes Control and Complications Trial Research Group The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus N Engl J Med 329 1993 977 986
66. JW Baynes JF Dey CG Ingelberetsen WR Ingelberestsen SR Thorpe Non-enzymatic glycosylation of serum proteins and hemoglobin: Response to changes in blood glucose levels in diabetic rats Diabetes 29 1980 524 527
67. DG Dyer JA Dunn SR Thorpe KE Bailie TJ Lyons DR McCance JW Baynes Accumulation of Maillard reaction products in skin collagen in diabetes and aging J Clin Invest 91 1993 2463 2469
68. FG Njoroge VM Monnier The chemistry of the Maillard reaction under physiological conditions: A review Prog Clin Biol Res 304 1989 85 107
69. HF Bunn KH Gabbay PM Gallop The glycosylated hemoglobin: Relevance to diabetes mellitus Science 200 1978 21 27
70. S Lal BS Szwergold AH Taylor WC Randall F Kappler KJ Wells-Knecht JW Baynes TR Brown Metabolism of fructose-3-phosphate in the diabetic rat lens Arch Biochem Biophys 318 1995 191 199
71. KJ Wells-Knecht TJ Lyons DR McCance SR Thorpe MS Feather JW Baynes 3-Deoxy glucose concentrations are increased in human plasma and urine in diabetes Diabetes 43 1994 1152 1156
72. T Danne MJ Spiro R Spiro Effect of high glucose on type IV collagen production by cultured glomerular epithelial, endothelial and mesangial cells Diabetes 42 1992 170 177
73. G Wolf K Sharma Y Chen M Ericksen FN Ziyadeh High glucose–induced proliferation in mesangial cells is reversed by autocrine TGF-beta Kidney Int 42 1992 647 656
74. T Niwa T Katsuzaki S Miyazaki T Miyazaki Y Ishizaki F Hayase N Tatemichi Y Takei Immunohistochemical detection of imidazolone, a novel advanced glycation end product, in kidneys and aortas of diabetic patients J Clin Invest 99 1997 1272 1280
75. PJ Beisswenger Z Makita TJ Curphey LL Moore S Jean T Brinck-Johnsen R Bucala H Vlassara Formation of immunochemical advanced glycosylation end products precedes and correlates with early manifestations of renal and retinal disease in diabetes Diabetes 44 1995 824 829
76. TJ Berg HJ Bangstad PA Torjesen R Osterby R Bucala KF Hanssen Advanced glycation end products in serum predict changes in the kidney morphology of patients with insulin-dependent diabetes mellitus Metabolism 46 1997 661 665
77. EA Friedman Diabetic nephropathy strategies in prevention and management Kidney Int 21 1982 720 738
78. M Sabbatini G Sansone F Uccello A Giliberti G Conte VE Andreucci Early glycosylation products induce glomerular hyperfiltration in normal rats Kidney Int 42 1992 875 881
79. BA McVerry AF Hopp RR Huehns Production of pseudodiabetic renal glomerular changes in mice after repeated injections of glycosylated proteins Lancet 2 1980 738 740
80. T Soules-Liparota M Cooper D Papazoglou B Clarke G Jerums Retardation by aminoguanidine of development of albuminuria, mesangial expansion and tissue fluorescence in streptozocin-induced diabetic rat Diabetes 40 1991 1328 1335
81. M Brownlee A Cerami H Vlassara Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications New Engl J Med 318 1988 1315 1321
82. K Horie T Miyata T Yasuda A Takeda Y Yasuda K Maeda G Sobue K Kurokawa Immunohistochemical localization of advanced glycation end products, pentosidine, and carboxymethyllysine in lipofuscin pigments of Alzheimer's disease and aged neurons Biochem Biophys Res Commun 236 1997 327 332
83. H Makino K Shikata K Hironaka M Kushiro Y Yamasaki H Sugimoto Z Ota N Araki S Horiuchi Ultrastructure of nonenzymatically glycated mesangial matrix in diabetic nephropathy Kidney Int 48 1995 517 526
84. G Pugliese F Pricci G Romeo F Pugliese P Mene S Giannini B Cresci G Galli CM Rotella H Vlassara MU Di Upregulation of mesangial growth factor and extracellular matrix synthesis by advanced glycation end products via a receptor-mediated mechanism Diabetes 46 1997 1881 1887
85. MP Cohen K Sharma Y Jin Prevention of diabetic nephropathy in db/db mice with glycated albumin antagonist: A novel treatment strategy J Clin Invest 95 1995 2338 2345
86. SM Lee A Graham Early immunopathologic events in experimental diabetic nephropathy: A study in db/db mice Exp Mol Pathol 33 1980 323 332
87. T Miyata Y Ueda Y Yamada Y Izuhara T Wada M Jadoul A Saito K Kurokawa C van Ypersele de Strihou Accumulation of carbonyl accelerates the formation of pentosidine, an advanced glycation end product: Carbonyl stress in uremia J Am Soc Nephrol 9 1998 2349 2356
88. T Miyata C van Ypersele de Strihou K Kurokawa JW Baynes Alterations in nonenzymatic biochemistry in uremia: Origin and significance of “carbonyl stress” in long-term uremic complications Kidney Int 55 1999 389 399
89. T Miyata Y Ueda T Shinzato Y Iida H Tanaka K Kurokawa C van Ypersele de Strihou K Maeda Accumulation of albumin-linked and free-form pentosidine in the circulation of uremic patients with end-stage renal failure: Renal implications in the pathophysiology of pentosidine J Am Soc Nephrol 7 1997 1198 1206
90. T Miyata MX Fu K Kurokawa C van Ypersele de Strihou SR Thorpe JW Baynes Products of autoxidation of both carbohydrates and lipids are increased in uremic plasma: Evidence for a generalized increase in oxidative stress in uremia? Kidney Int 54 1998 1290 1295
91. A Mlakar G Spiteller Reinvestigation of lipid peroxidation of linolenic acid Biochem Biophys Acta 1214 1994 209 220
92. PJ Thornalley M Westwood TW Lo AC McLellan Formation of methylglyoxal-modified proteins in vitro and in vivo and their involvement in AGE-related processes Contrib Nephrol 112 1995 24 31
93. T Niwa T Katsuzaki T Momoi S Miyazaki A Ogawa A Satto K Maeda N Tatemichi I Takei Modification of β2 m with advanced glycation end products as observed in dialysis-related amyloidosis by 3-DG accumulating in uremic serum Kidney Int 49 1999 867
94. H Odani T Shinzato J Usami Y Matsumoto E Brinkmann Frye JW Baynes K Maeda Imidazolium cross-links derived from reaction of lysine with glyoxal and methylglyoxal are increased in serum proteins of uremic patients: Evidence for increased oxidative stress in uremia FEBS Lett 427 1998 381 385
95. Y Ueda T Miyata T Hashimoto H Yamada Y Izuhara H Sakai K Kurokawa Implication of altered redox regulation by antioxidant enzymes in the increased plasma pentosidine, an advanced glycation end product, in uremia Biochem Biophys Res Commun 245 1998 785 790
96. H Vlassara Recent progress on the biologic and clinical significance of advanced glycosylation end products J Lab Clin Med 124 1994 19 30
97. T Miyata K Maeda K Kurokawa C van Ypersele de Strihou Oxidation conspires with glycation to generate noxious advanced glycation end products in renal failure Nephrol Dial Transplant 12 1997 255 258
98. P Verbeke M Perichon C Borot-Laloi J Schaeverbeke H Bakala Accumulation of advanced glycation end products in the rat nephron: Link with circulating AGEs during aging J Histochem Cytochem 45 1997 1059 1068
99. H Vlassara LJ Striker S Teichberg H Fuh YM Li M Steffes Advanced glycation end products induce glomerular sclerosis and albuminuria in normal rats Proc Natl Acad Sci U S A 91 1994 11704 11708
100. J Boyd-White JC Williams Jr Effect of cross-linking on matrix permeability. A model for age-modified basement membranes Diabetes 45 1996 348 353
101. BS Daniel EB Hauser Glycation of albumin not glomerular basement membrane alters permeability in an in vitro model Diabetes 41 1992 1415 1421
102. S Gupta V Rifici S Crowley M Brownlee Z Shan D Schlondorff Interactions of LDL and modified LDL with mesangial cells and matrix Kidney Int 41 1992 1161 1169
103. BH Scribner AL Babb Evidence for toxins of “middle” molecular weight Kidney Int 7 suppl 2 1975 349 351
104. T Miyata Y Wada K Maeda Beta 2-microglobulin modified with the AGE products of the Maillard reaction in dialysis-related amyloidosis Contrib Nephrol 112 1995 52 64
105. MA Friedlander V Witko-Sarsat AT Nguyen YC Wu M Labrunte C Verger P Jungers B Descamps-Latscha The advanced glycation end product pentosidine and monocyte activation in uremia Clin Nephrol 45 1996 379 382
106. S Yoshida K Yamada K Hamaguchi M Nishimura E Hatakeyama H Tsuchida K Sakamoto H Kashiwabara T Yokoyama K Ikeda S Horiuchi Immunohistochemical study of human advanced glycation end-products (AGE) and growth factors in cardiac tissues of patients on maintenance dialysis and with kidney transplantation Clin Nephrol 49 1998 273 280
107. T Miyata O Oda R Inagi Y Iida N Araki N Yamada S Horiuchi N Taniguchi K Maeda T Kinoshita Beta 2-microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis J Clin Invest 92 1993 1243 1252
108. WFJ Owen FF Hou RO Stuart J Kay J Boyce GM Chertow AM Schmidt Beta 2-microglobulin modified with advanced glycation end products modulates collagen synthesis by human fibroblasts Kidney Int 53 1998 1365 1373
109. FF Hou GM Chertow J Kay J Boyce JM Lazarus JA Braatz WF Owen Jr Interaction between beta 2-microglobulin and advanced glycation end products in the development of dialysis-related amyloidosis Kidney Int 51 1997 1514 1519
110. FF Hou J Boyce GM Chertow J Kay WF Owen Jr Aminoguanidine inhibits advanced glycation end product formation on beta2-microglobulin J Am Soc Nephrol 9 1998 277 283
111. S Fishbane R Bucala BJ Pereira H Founds H Vlassara Reduction of plasma apolipoprotein B by effective removal of circulating glycation derivatives in uremia Kidney Int 52 1997 1645 1650
112. S Horiuchi N Araki Advanced glycation end products of the Maillard reaction and their relation to aging Gerontology 40 suppl 2 1994 S10 S15
113. H Vlassara M Brownlee K Manogue CA Dinarello A Pasagian Calchectin/TNF and IL-1 induced by glucose-modified proteins: Role in normal tissue remodeling Science 240 1988 1546 1548
114. DR Sell VM Monnier Structure elucidation of a senescence cross-link from human extracellular matrix. Implication of pentoses in the aging process J Biol Chem 264 1986 21597 21602
115. SD Yan X Chen AM Schmidt J Brett G Godman YS Zou CW Scott C Caputo T Frappier MA Smith Glycated tau protein in Alzheimer disease: A mechanism for induction of oxidant stress Proc Natl Acad Sci U S A 91 1994 7787 7791
116. S Yamagishi Y Yamamoto S Harada CC Hsu H Yamamoto Advanced glycosylation end products stimulate the growth but inhibit the prostacyclin-producing ability of endothelial cells through interactions with their receptors FEBS Lett 384 1996 103 106
117. H Vlassara H Fuh Z Makita S Krungkrai A Cerami R Bucala Exogenous advanced glycosylation end products induce complex vascular dysfunction in normal animals: A model for diabetic and aging complications Proc Natl Acad Sci U S A 89 1992 12043 12047
118. C Baylis R Schmidt The aging glomerulus Semin Nephrol 16 1996 265 276
119. N Traverso P Odetti MA Pronzato UM Marinari D Cottalasso Intensive insulin treatment reduces the accumulation of oxidation and glycation end-products in diabetic rat collagen Aging 9 1997 432 433
120. H Sano T Higashi K Matsumoto J Melkko Y Jinnouchi K Ikeda Y Ebina H Makino B Smedsrod S Horiuchi Insulin enhances macrophage scavenger receptor-mediated endocytic uptake of advanced glycation end products J Biol Chem 273 1998 8630 8637
121. M Sensi F Pricci MG De Rossi S Morano U Di Marolo D -Lysine effectively decreases the non-enzymatic glycation of proteins in vitro Clin Chem 35 1989 384 387
122. M Khatami Z Suldan I David W Li JH Rockey Inhibitory effects of pyridoxal phosphate, ascorbate and aminoguanidine on nonenzymatic glycosylation Life Sci 43 1988 1725 1731
123. IA Troncoso MM Esteban MA Ruiz L Florez L Barneo In vitro advanced glycation end product formation in rat tail tendon fibers: Influence of aminoguanidine Transplant Proc 27 1995 3345 3346
124. M Brownlee H Vlassara A Kooney P Ulrich A Cerami Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking Science 232 1986 1629 1632
125. CW Yang H Vlassara EP Peten CJ He GE Striker LJ Striker Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease Proc Natl Acad Sci U S A 91 1994 9436 9440
126. S Youssef DT Nguyen T Soulis S Panagiotopoulos G Jerums M Cooper Effect of aminoguanidine therapy on renal advanced glycation end products Kidney Int 55 1999 907 916
127. MS Huijberts BH Wolffenbuttel FR Crijns AC Nieuwenhuijzen Kruseman MH Bemelmans HA Struijker Boudier Aminoguanidine reduces regional albumin clearance but not urinary albumin excretion in streptozotocin-diabetic rats Diabetologia 37 1994 10 14
128. Y Miyauchi H Shikama T Takasu H Okamiya M Umeda E Hirasaki I Ohhata H Nakayama S Hakagawa Slowing of peripheral motor nerve conduction was ameliorated by aminoguanidine in streptozotocin-induced diabetic rats Eur J Endocrinol 134 1996 467 473
129. HP Hammes D Strodter A Weiss RG Bretzel K Federlin M Brownlee Secondary intervention with aminoguanidine retards the progression of diabetic retinopathy in the rat model Diabetologia 38 1995 656 660
130. GR Norton G Candy AJ Woodisiss Aminoguanidine prevents the decreased myocardial compliance produced by streptozotocin-induced diabetes in rats Circulation 93 1996 1905 1912
131. EA Friedman DA Distant JF Fleishhacker TA Boyd K Cartwright Aminoguanidine prolongs survival in azotemic-induced diabetic rats Am J Kidney Dis 30 1997 253 259
132. S Nakamura Z Makita S Ishikawa K Yasumura W Fujii K Yanagisawa T Kawata T Koike Progression of nephropathy in spontaneous diabetic rats is prevented by OPB-9195, a novel inhibitor of advanced glycation Diabetes 46 1997 895 899
133. AA Booth RG Khalifah BG Hudson Thiamine pyrophosphate and pyridoxamine inhibit the formation of antigenic advanced glycation end-products: Comparison with aminoguanidine Biochem Biophys Res Commun 220 1996 113 119
134. S Vasan X Zhang A Kapurniotu J Bernhagen S Teichberg J Basgen D Wagle D Shih I Terlecky R Bucala A Cerami J Egan P Ulrich An agent cleaving glucose-derived protein cross-links in vitro and in vivo Nature 382 1996 275 278
135. BH Wolffenbuttel CM Boulanger FR Crijns MS Huijberts P Poitevin GN Swennen S Vasan JJ Egan P Ulrich A Cerami BI Levy Breakers of advanced glycation end products restore large artery properties in experimental diabetes Proc Natl Acad Sci U S A 95 1998 4630 4634
136. MA Friedlander YC Wu JA Schulak VM Monnier DE Hricik Influence of dialysis modality on plasma and tissue concentrations of pentosidine in patients with end-stage renal disease Am J Kidney Dis 25 1995 445 451
137. A Ateshkadi CA Johnson HW Founds SW Zimmerman Serum advanced glycosylation end-products in patients on hemodialysis and CAPD Perit Dial Int 15 1995 129 133
138. T Miyata Y Ueda A Yoshida S Sugiyama Y Iida M Jadoul K Maeda K Kurokawa C van Ypersele de Strihou Clearance of pentosidine, an advanced glycation end product, by different modalities of renal replacement therapy Kidney Int 51 1997 880 887
139. T Mitsuhashi YM Li S Fishbane H Vlassara Depletion of reactive advanced glycation end products from diabetic uremic sera using a lysozyme-linked matrix J Clin Invest 100 1997 847 854
140. JW Dobbie New concepts in molecular biology and ultrastructural pathology of the peritoneum: Their significance for peritoneal dialysis Am J Kidney Dis 15 1990 97 109
141. EJ Lamb WR Cattell AB Dawnay In vitro formation of advanced glycation end products in peritoneal dialysis fluid Kidney Int 47 1995 1768 1774
142. T Linden G Forsback R Deppisch T Henle A Wieslander 3-Deoxyglucosone, a promoter of advanced glycation end products in fluids for peritoneal dialysis Perit Dial Int 18 1998 290 293
143. WK Lee M Akyol S Shaw MH Dominiczak JD Briggs Kidney transplantation decreases the tissue level of advanced glycosylation end-products Nephrol Dial Transplant 10 1995 103 107
144. DE Hricik JA Schulak DR Sell JF Fogarty VM Monnier Effects of kidney or kidney-pancreas transplantation on plasma pentosidine Kidney Int 43 1993 398 403
145. K Nicholls TE Mandel Advanced glycosylation end-products in experimental murine diabetic nephropathy: Effect of islet isografting and of aminoguanidine Lab Invest 60 1989 486 491
146. R Bucala H Vlassara A Cerami Drug Dev Res 32 1994 77