Efficacy of liposomal amphotericin B with prolonged circulation in blood in treatment of severe pulmonary aspergillosis in leukopenic rats

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 3, 2000, Pages 540-545

  Van Etten, Els W M ^a   Stearne Cullen, Lorna E T ^a   Ten Kate, Marian T ^a   Bakker Woudenberg, Irma A J M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B LIPID COMPLEX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; FEMALE; FUNGUS GROWTH; LEUKOCYTE COUNT; LEUKOPENIA; LUNG ASPERGILLOSIS; MYCELIUM; NONHUMAN; PRIORITY JOURNAL; RAT;

AMPHOTERICIN B; ANIMALS; ANTIBIOTICS, ANTIFUNGAL; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; DRUG CARRIERS; FEMALE; HUMANS; IMMUNOSUPPRESSION; LEUKOCYTE COUNT; LEUKOPENIA; LIPOSOMES; LUNG DISEASES, FUNGAL; POLYETHYLENE GLYCOLS; RATS; TREATMENT OUTCOME;

EID: 0033996646     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.3.540-545.2000     Document Type: Article

References (35)

1. Allen, S. D., K. N. Sorensen, M. J. Nejdl, C. Durrant, and R. T. Proffitt. 1994. Prophylactic efficacy of aerosolized liposomal (AmBisome) and non-liposomal (Fungizone) amphotericin B in murine pulmonary aspergillosis. J. Antimicrob. Chemother. 34:1001-1013.
2. Allende, M. C., J. W. Lee, P. Francis, K. Garrett, H. Dollenberg, J. Berenguer, C. A. Lyman, P. A. Pizzo, and T. J. Walsh. 1994. Dose-dependent antifungal activity and nephrotoxicity of amphotericin B colloidal dispersion in experimental pulmonary aspergillosis. Antimicrob. Agents Chemother. 38:518-522.
3. Ames, B. N., and D. T. Dubin. 1960. The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid. J. Biol. Chem. 235:769-775.
4. Anaissie, E. J., G. N. Mattiuzzi, C. B. Miller, G. A. Noskin, M. J. Gurwith, R. D. Mamelok, and L. A. Pietrelli. 1998. Treatment of invasive fungal infections in renally impaired patients with amphotericin B colloidal dispersion. Antimicrob. Agents Chemother. 42:606-611.
5. Bakker-Woudenberg, I. A., A. F. Lokerse, M. T. ten Kate, J. W. Mouton, M. C. Woodle, and G. Storm. 1993. Liposomes with prolonged blood circulation and selective localization in Klebsiella pneumoniae-infected lung tissue. J. Infect. Dis. 168:164-171.
6. Bakker-Woudenberg, I. A., M. T. ten Kate, L. E. Stearne-Cullen, and M. C. Woodle. 1995. Efficacy of gentamicin or ceftazidime entrapped in liposomes with prolonged blood circulation and enhanced localization in Klebsiella pneumoniae infected lung tissue. J. Infect. Dis. 171:938-947.
7. Bowden, R. A., M. Cays, T. Gooley, R. D. Mamelok, and J. A. van Burik. 1996. Phase I study of amphotericin B colloidal dispersion for the treatment of invasive fungal infections after marrow transplant. J. Infect. Dis. 173: 1208-1215.
8. Cicogna, C. E., M. H. White, E. M. Bernard, T. Ishimura, M. Sun, W. P. Tong, and D. Armstrong. 1997. Efficacy of prophylactic aerosol amphotericin B lipid complex in a rat model of pulmonary aspergillosis. Antimicrob. Agents Chemother. 41:259-261.
9. Clark, J. M., R. R. Whitney, S. J. Olsen, R. J. George, M. R. Swerdel, R. Kunselman, and D. P. Bonner. 1991. Amphotericin B lipid complex therapy of experimental fungal infections in mice. Antimicrob. Agents Chemother. 35:615-621.
10. Denning, D. W. 1998. Invasive aspergillosis. Clin. Infect. Dis. 26:781-803.
11. Ellis, M., D. Spence, B. de Pauw, F. Meunier, A. Marinus, L. Collette, R. Sylvester, J. Meis, M. Boogaerts, D. Selleslag, V. Kremery, W. von Sinner, P. MacDonald, C. Doyen, and B. van der Cam. 1998. An EORTC international multicenter randomized trial (EORTC number 19923) comparing two dosages of liposomal amphotericin B for treatment of invasive aspergillosis. Clin. Infect. Dis. 27:1406-1412.
12. Francis, P., J. W. Lee, A. Hoffman, J. Peter, A. Francesconi, J. Bacher, J. Shelhamer, P. A. Pizzo, and T. J. Walsh. 1994. Efficacy of unilamellar liposomal amphotericin B in treatment of pulmonary aspergillosis in persistently granulocytopenic rabbits: the potential role of bronchoalveolar D-mannitol and serum galactomannan as markers of infection. J. Infect. Dis. 169:356-368.
13. Hiemenz, J. W., and T. J. Walsh. 1996. Lipid formulations of amphotericin B: recent progress and future directions. Clin. Infect. Dis. 22(Suppl. 2):S133-S144.
14. Krüger, W., M. Stockschläder, B. Rüssmann, C. Berger, M. Hoffknecht, I. Sobottka, B. Kohlschütter, G. Kroschke, N. Kröger, M. Horstmann, H. Kabisch, and A. R. Zander. 1995. Experience with liposomal amphotericin B in 60 patients undergoing high-dose therapy and bone marrow or peripheral blood stem cell transplantation. Br. J. Haematol. 91:684-690.
15. Leenders, A. C., S. de Marie, M. T. ten Kate, I. A. Bakker-Woudenberg, and H. A. Verbrugh. 1996. Liposomal amphotericin B (AmBisome) reduces dissemination of infection as compared to amphotericin B deoxycholate (Fungizone) in a rat model of pulmonary aspergillosis. J. Antimicrob. Chemother. 38:215-225.
16. Leenders, A. C., S. Daenen, R. L. H. Jansen, W. C. J. Hop, B. Lowenberg, P. W. Wijermans, J. Cornelissen, R. Herbrecht, H. van der Lelie, H. C. Hoogsteden, H. A. Verbrugh, and S. de Marie. 1998. AmBisome compared with amphotericin B deoxycholate in the treatment of neutropenia-associated invasive fungal infections. Br. J. Haematol. 103:205-212.
17. Mehta, J., S. Kelsey, P. Chu, R. Powles, D. Hazel, U. Riley, C. Evans, A. Newland, J. Treleaven, and S. Singhal. 1997. Amphotericin B lipid complex (ABLC) for the treatment of confirmed or presumed fungal infections in immunocompromised patients with hematologic malignancies. Bone Marrow Transplant. 20:39-43.
18. Myint, H., A. A. Kyi, and R. M. Winn. 1998. An open, non-comparative evaluation of the efficacy and safety of amphotericin B lipid complex as treatment of neutropenic patients with presumed or confirmed pulmonary fungal infections. J. Antimicrob. Chemother. 41:424-426.
19. Otsubo, T., K. Maruyama, S. Maesaki, Y. Miyazaki, E. Tanaka, T. Takizawa, K. Moribe, K. Tomono, T. Tashiro, and S. Kohno. 1998. Long-circulating immunoliposomal amphotericin B against invasive pulmonary aspergillosis in mice. Antimicrob. Agents Chemother. 42:40-44.
20. Patterson, T. F., P. Miniter, J. Dijkstra, F. C. Szoka, J. L. Ryan, and V. T. Andriole. 1989. Treatment of experimental invasive aspergillosis with novel amphotericin B/cholesterol sulfate complexes. J. Infect. Dis. 159:717-724.
21. Prentice, H. G., I. M. Hann, R. Herbrecht, M. Aoun, S. Kvaloj, D. Catovsky, C. R. Pinkerton, S. A. Schey, F. Jacobs, A. Oakhill, R. F. Stevens, P. J. Darbyshire, and B. E. Gibson. 1997. A randomized comparison of liposomal versus conventional amphotericin B for the treatment of pyrexia of unknown origin in neutropenic patients. Br. J. Haematol. 98:711-718.
22. Purcell, I. F., and P. A. Corris. 1995. Use of nebulized liposomal amphotericin B in the treatment of Aspergillus fumigatus empyema. Thorax 50:1321-1323.
23. Swenson, C. E., W. R. Perkins, P. Roberts, I. Ahmad, R. Stevens, D. A. Stevens, and A. S. Janoff. 1998. In vitro and in vivo antifungal activity of amphotericin B lipid complex: are phospholipases important? Antimicrob. Agents Chemother. 42:767-771.
24. Van Etten, E. W., M. Otte-Lambillion, W. van Vianen, M. T. ten Kate, and I. A. Bakker-Woudenberg. 1995. Biodistribution of liposomal amphotericin B (AmBisome) and amphotericin B-desoxycholate (Fungizone) in uninfected immunocompetent mice and leucopenic mice infected with Candida albicans. J. Antimicrob. Chemother. 35:509-519.
25. Van Etten, E. W., W. van Vianen, R. H. Tijhuis, G. Storm, and I. A. Bakker-Woudenberg. 1995. Sterically stabilized amphotericin B-liposomes: toxicity and biodistribution in mice. J. Control. Release 37:123-129.
26. Van Etten, E. W., M. T. ten Kate, L. E. Stearne, and I. A. Bakker-Woudenberg. 1995. Amphotericin B liposomes with prolonged circulation in blood: in vitro antifungal activity, toxicity, and efficacy in systemic candidiasis in leukopenic mice. Antimicrob. Agents Chemother. 39:1954-1958.
27. Van Etten, E. W., S. V. Snijders, W. van Vianen, and I. A. Bakker-Woudenberg. 1998. Superior efficacy of liposomal amphotericin B with prolonged circulation in blood in the treatment of severe candidiasis in leukopenic mice. Antimicrob. Agents Chemother. 42:2431-2433.
28. Walsh, T. J., K. Garrett, E. Feuerstein, M. Girton, M. Allende, J. Bacher, A. Francesconi, R. Schaufele, and P. A. Pizzo. 1995. Therapeutic monitoring of experimental invasive pulmonary aspergillosis by ultrafast computerized tomography, a novel, noninvasive method for measuring responses to antifungal therapy. Antimicrob. Agents Chemother. 39:1065-1069.
29. Walsh, T. J., J. W. Hiemenz, N. L. Seibel, J. R. Perfect, G. Horwith, L. Lee, J. L. Silber, M. J. DiNubile, A. Reboli, E. Bow, J. Lister, and E. J. Anaissie. 1998. Amphotericin B lipid complex for invasive fungal infections: analysis of safety and efficacy in 556 cases. Clin. Infect. Dis. 26:1383-1396.
30. Walsh, T. J., V. Yeldandi, M. McEvoy, C. Gonzalez, S. Chanock, A. Freifeld, N. I. Seibel, P. O. Whitcomb, P. Jarosinski, G. Boswell, I. Bekersky, A. Alak, D. Buell, J. Barret, and W. Wilson. 1998. Safety, tolerance, and pharmacokinetics of a small unilamellar liposomal formulation of amphotericin B (AmBisome) in neutropenic patients. Antimicrob. Agents Chemother. 42: 2391-2398.
31. Walsh, T. J., R. W. Finberg, C. Arndt, J. Hiemenz, C. Schwartz, D. Bodensteiner, P. Pappas, N. Seibel, R. N. Greenberg, S. Dummer, M. Schuster, and J. S. Holcenberg. 1999. Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. National Institute of Allergy and Infectious Diseases Mycoses Study Group. N. Engl. J. Med. 340:764-771.
32. Walsh, T. J., N. L. Seibel, C. Arndt, R. E. Harris, M. J. Dinubile, A. Reboli, J. Hiemenz, and S. J. Chanock. 1999. Amphotericin B lipid complex in pediatric patients with invasive fungal infections. Pediatr. Infect. Dis. J. 18:702-708.
33. White, M. H., E. J. Anaissie, S. Kusne, J. R. Wingard, J. W. Hiemenz, A. Cantor, M. Gurwith, C. Du Mond, R. D. Mamelok, and R. A. Bowden. 1997. Amphotericin B colloidal dispersion vs. amphotericin B as therapy for invasive aspergillosis. Clin. Infect. Dis. 24:635-642.
34. Wingard, J. R. 1997. Efficacy of amphotericin lipid complex injection (ABLC) in bone marrow transplant recipients with life-threatening systemic mycoses. Bone Marrow Transplant. 19:343-347.
35. Woodle, M. C., M. S. Newman, and J. A. Cohen. 1994. Sterically stabilized liposomes: physical and biological properties. J. Drug. Target. 2:397-403.