-
1
-
-
0030043446
-
Cancer Statistics, 1996
-
Parker, S.L., Tang, T., Bolden, S., Wingo, P.A.: Cancer Statistics, 1996. CA Cancer J. Clin. 46:5-9, 1996
-
(1996)
CA Cancer J. Clin.
, vol.46
, pp. 5-9
-
-
Parker, S.L.1
Tang, T.2
Bolden, S.3
Wingo, P.A.4
-
2
-
-
0000935984
-
Colorectal cancer
-
T. De Vita Jr., S. Hellman, S. Rosenberg, editors. Philadelphia, Lippincott
-
Cohen, A.M., Shank, B., Friedman: Colorectal cancer. In Cancer: Principles and Practice of Oncology. T. De Vita Jr., S. Hellman, S. Rosenberg, editors. Philadelphia, Lippincott, 1989, pp. 2275-2298
-
(1989)
Cancer: Principles and Practice of Oncology
, pp. 2275-2298
-
-
Cohen, A.M.1
Shank, B.2
Friedman3
-
3
-
-
0028838680
-
Colorectal cancer: Hepatic-directed therapy - the role of surgery, regional chemotherapy and novel modalities
-
Kemeny, M.M., Busch, E.: Colorectal cancer: hepatic-directed therapy - the role of surgery, regional chemotherapy and novel modalities. Semin. Oncol. 22:494, 1995
-
(1995)
Semin. Oncol.
, vol.22
, pp. 494
-
-
Kemeny, M.M.1
Busch, E.2
-
4
-
-
33745464490
-
Fluorinated pyrimidincs: A new class of tumor inhibitory compounds
-
Heidelberger, C., Chauchuri, N.K., Danenberg, P., et al.: Fluorinated pyrimidincs: a new class of tumor inhibitory compounds. Nature 179:663, 1957
-
(1957)
Nature
, vol.179
, pp. 663
-
-
Heidelberger, C.1
Chauchuri, N.K.2
Danenberg, P.3
-
5
-
-
0017251401
-
Large bowel cancer: The current status of treatment
-
Carter, S.K.: Large bowel cancer: the current status of treatment. J. Natl. Cancer Inst. 56:3, 1976
-
(1976)
J. Natl. Cancer Inst.
, vol.56
, pp. 3
-
-
Carter, S.K.1
-
7
-
-
0029067247
-
Chemotherapy for colorectal carcinoma: One small step forward, one step backward
-
Kemeny, N.: Chemotherapy for colorectal carcinoma: one small step forward, one step backward. J. Clin. Oncol. 13:1287, 1995
-
(1995)
J. Clin. Oncol.
, vol.13
, pp. 1287
-
-
Kemeny, N.1
-
8
-
-
70449226465
-
Clinical studies with 5-fluorouracil
-
Curreri, A.R., Ansfield, F.J., McIver, T.A., Weisman, H.A., Heidelberger, C.: Clinical studies with 5-fluorouracil. Cancer Res. 18:418, 1958
-
(1958)
Cancer Res.
, vol.18
, pp. 418
-
-
Curreri, A.R.1
Ansfield, F.J.2
McIver, T.A.3
Weisman, H.A.4
Heidelberger, C.5
-
9
-
-
0017336879
-
A phase III study comparing the clinical utility of four regimens of 5-fluorouracil
-
Ansfield, R., Klotz, J., Nealon, T., Ansfield, R., Klotz, J., Nealon, T., Rainirez, G., Minton, J., Hill, G., Wilson, W., Davis, H., Cornell, G.: A phase III study comparing the clinical utility of four regimens of 5-fluorouracil. Cancer 39:34, 1977
-
(1977)
Cancer
, vol.39
, pp. 34
-
-
Ansfield, R.1
Klotz, J.2
Nealon, T.3
Ansfield, R.4
Klotz, J.5
Nealon, T.6
Rainirez, G.7
Minton, J.8
Hill, G.9
Wilson, W.10
Davis, H.11
Cornell, G.12
-
10
-
-
15644372530
-
Therapy with the fluorinated pyrimidines
-
C.G. Moertel, R.J. Reitemeier, editors. New York, Hoeber-Harper
-
Moertel, C.G., Reitemeyer, R.J.A., Moertel, C.G., Reitemeier, R.J., Hahn, R.G.: Therapy with the fluorinated pyrimidines. In Advanced Gastrointestinal Cancer, C.G. Moertel, R.J. Reitemeier, editors. New York, Hoeber-Harper, 1969, pp. 86-107
-
(1969)
Advanced Gastrointestinal Cancer
, pp. 86-107
-
-
Moertel, C.G.1
Reitemeyer, R.J.A.2
Moertel, C.G.3
Reitemeier, R.J.4
Hahn, R.G.5
-
11
-
-
0343221611
-
5-Fluorouracil plus leucovorin in cancer therapy
-
V.T. De Vita Jr., S. Hellman, S.A. Rosenberg, editors. Philadelphia, Lippincott
-
Grem, J.L.: 5-Fluorouracil plus leucovorin in cancer therapy. In Principles and Practice of Oncology (2nd ed., vol. 2), V.T. De Vita Jr., S. Hellman, S.A. Rosenberg, editors. Philadelphia, Lippincott, 1988, pp. 1-13
-
(1988)
Principles and Practice of Oncology 2nd Ed.
, vol.2
, pp. 1-13
-
-
Grem, J.L.1
-
12
-
-
0020652672
-
Fluorinated pyrimidines and their nucleosides
-
A. Meiste, editor, New York, John Wiley and Sons
-
Heidelberger, C., Danenberg, P.V., Moran, R.G.: Fluorinated pyrimidines and their nucleosides. In: Advances in Enzymology and Related Areas in Molecular Biology, A. Meiste, editor, New York, John Wiley and Sons, 1983, pp. 57-119
-
(1983)
Advances in Enzymology and Related Areas in Molecular Biology
, pp. 57-119
-
-
Heidelberger, C.1
Danenberg, P.V.2
Moran, R.G.3
-
13
-
-
0023462477
-
Overview of the current status and future direction of clinical trials with 5-fluorouracil in combination with folinic acid
-
Grem, J.L., Hoth, D.F., Hamilton, J.M.: Overview of the current status and future direction of clinical trials with 5-fluorouracil in combination with folinic acid. Cancer Treat. Rep. 77:1249, 1987
-
(1987)
Cancer Treat. Rep.
, vol.77
, pp. 1249
-
-
Grem, J.L.1
Hoth, D.F.2
Hamilton, J.M.3
-
14
-
-
0004514823
-
Fluoropyrimidine activity and resistance at the cellular level
-
D. Kessel, editor. Boca Raton, FL, CRC Press
-
Armstrong, R.D.: Fluoropyrimidine activity and resistance at the cellular level. In Resistance to Antineoplastic Drugs, D. Kessel, editor. Boca Raton, FL, CRC Press, 1989, pp. 317-351
-
(1989)
Resistance to Antineoplastic Drugs
, pp. 317-351
-
-
Armstrong, R.D.1
-
15
-
-
33947093786
-
Effect of 5′10-methylenetetrahydrofolate on the dissociation of 5-fluoro-2-deoxyuridylate from thymidylate synthetase: Evidence for an ordered mechanism
-
Danenberg, P.V., Danenberg, K.D.: Effect of 5′10-methylenetetrahydrofolate on the dissociation of 5-fluoro-2-deoxyuridylate from thymidylate synthetase: evidence for an ordered mechanism. Biochemistry 17:4018, 1978
-
(1978)
Biochemistry
, vol.17
, pp. 4018
-
-
Danenberg, P.V.1
Danenberg, K.D.2
-
16
-
-
0005086073
-
Cytotoxicity of 5-flouro-2-dcoxyuridine: Requirement for reduced folate cofactors and antagonism by methotrexate
-
Ullman, B., Lee, M., Martin, D.W., Ullman, B., Lee, M., Martin, D.W., Santi, D.U.: Cytotoxicity of 5-flouro-2-dcoxyuridine: requirement for reduced folate cofactors and antagonism by methotrexate. Proc. Natl. Acad. Sci. U.S.A. 75:980, 1978
-
(1978)
Proc. Natl. Acad. Sci. U.S.A.
, vol.75
, pp. 980
-
-
Ullman, B.1
Lee, M.2
Martin, D.W.3
Ullman, B.4
Lee, M.5
Martin, D.W.6
Santi, D.U.7
-
17
-
-
0019349301
-
Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinoma in mice
-
Houghton, J.A., Maroda, S.J., Phillips, J.O., Houghton, P.J.: Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinoma in mice. Cancer Res. 41:144, 1981
-
(1981)
Cancer Res.
, vol.41
, pp. 144
-
-
Houghton, J.A.1
Maroda, S.J.2
Phillips, J.O.3
Houghton, P.J.4
-
18
-
-
0018125559
-
Pharmacokinetics of 5-fluorouracil in humans
-
MacMillan, W.E., Winberg, W.H., Welling, P.G.: Pharmacokinetics of 5-fluorouracil in humans. Cancer Res. 38:3479, 1978
-
(1978)
Cancer Res.
, vol.38
, pp. 3479
-
-
MacMillan, W.E.1
Winberg, W.H.2
Welling, P.G.3
-
19
-
-
0022320030
-
Cellular basis for the inefficiency of 5-fluorouracil in human colon carcinoma
-
Drewinko, B., Yang, L.Y.: Cellular basis for the inefficiency of 5-fluorouracil in human colon carcinoma. Cancer Treat. Rep. 69: 1391, 1985
-
(1985)
Cancer Treat. Rep.
, vol.69
, pp. 1391
-
-
Drewinko, B.1
Yang, L.Y.2
-
20
-
-
0023705723
-
Mechanisms of the cytotoxic synergism of fluoropyrimidines and folinic acid in mouse Ieukemic cells
-
Keyomarsi, K., Moran, R.G.: Mechanisms of the cytotoxic synergism of fluoropyrimidines and folinic acid in mouse Ieukemic cells. Biol. Chem. 263:14402, 1988
-
(1988)
Biol. Chem.
, vol.263
, pp. 14402
-
-
Keyomarsi, K.1
Moran, R.G.2
-
21
-
-
0026637845
-
Novel mechanisms of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules
-
Aschele, C., Sobreto, A., Fuderan, M.A., Bertino, J.R.: Novel mechanisms of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules. Cancer Res. 52:1855, 1992
-
(1992)
Cancer Res.
, vol.52
, pp. 1855
-
-
Aschele, C.1
Sobreto, A.2
Fuderan, M.A.3
Bertino, J.R.4
-
22
-
-
0018926163
-
Assessment of growth limiting events caused by 5-fluorouracil in mouse cells and human cells
-
Evans, R.M., Laskin, J.D., Hakala, M.T.: Assessment of growth limiting events caused by 5-fluorouracil in mouse cells and human cells. Cancer Res. 40:4113, 1980
-
(1980)
Cancer Res.
, vol.40
, pp. 4113
-
-
Evans, R.M.1
Laskin, J.D.2
Hakala, M.T.3
-
23
-
-
0001484744
-
Low-dose protracted 5-fluorouracil infusion in solid tumors
-
Izzo, J., Fandi, A., Villalobos, W., Azli, N., Bachouchi, M., Levin, F.M., Benahmed, M., Arinaud, J.P., Rougier, P., Cvitkovic, E.: Low-dose protracted 5-fluorouracil infusion in solid tumors. J Infus. Chemother. 4:135, 1954
-
(1954)
J Infus. Chemother.
, vol.4
, pp. 135
-
-
Izzo, J.1
Fandi, A.2
Villalobos, W.3
Azli, N.4
Bachouchi, M.5
Levin, F.M.6
Benahmed, M.7
Arinaud, J.P.8
Rougier, P.9
Cvitkovic, E.10
-
24
-
-
0028830956
-
Continuous infusion fluorouracil/leucovorin and bolus mitomycin-C as a salvage regimen in advanced colorectal cancer
-
Conti, J.A., Kemeny, N.E., Saltz, L.B., McKenzie, A.A., Grossano, D.D., Bertino, J.R. Continuous infusion fluorouracil/leucovorin and bolus mitomycin-C as a salvage regimen in advanced colorectal cancer. Cancer 25:769, 1995
-
(1995)
Cancer
, vol.25
, pp. 769
-
-
Conti, J.A.1
Kemeny, N.E.2
Saltz, L.B.3
McKenzie, A.A.4
Grossano, D.D.5
Bertino, J.R.6
-
25
-
-
0021927568
-
5-FU infusion in advanced colon cancer: A comparison of three dose schedules
-
Shah, A., MacDonald, W., Goldie, J., Gudauskas, G., Brisehois, B.: 5-FU infusion in advanced colon cancer: a comparison of three dose schedules. Cancer Treat. Rep. 69:7, 1985
-
(1985)
Cancer Treat. Rep.
, vol.69
, pp. 7
-
-
Shah, A.1
MacDonald, W.2
Goldie, J.3
Gudauskas, G.4
Brisehois, B.5
-
26
-
-
0016768026
-
Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma
-
Seifert, P., Baker, L., Reed, M.L., Vatitkevicius, V.K.: Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma. Cancer 36:123, 1975
-
(1975)
Cancer
, vol.36
, pp. 123
-
-
Seifert, P.1
Baker, L.2
Reed, M.L.3
Vatitkevicius, V.K.4
-
27
-
-
0016768026
-
Five day continuous infusion of 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma
-
Hartman, H.A., Kessinger, A., Lemon, H.M., Foley, J.F.: Five day continuous infusion of 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma. Cancer 36:123, 1975
-
(1975)
Cancer
, vol.36
, pp. 123
-
-
Hartman, H.A.1
Kessinger, A.2
Lemon, H.M.3
Foley, J.F.4
-
28
-
-
0019850673
-
Phase I study of protracted infusion of 5-fluorouracil
-
Lokich, J., Bothe, A., Fine, N., Perri, J.: Phase I study of protracted infusion of 5-fluorouracil. Cancer 48:2565, 1981
-
(1981)
Cancer
, vol.48
, pp. 2565
-
-
Lokich, J.1
Bothe, A.2
Fine, N.3
Perri, J.4
-
29
-
-
10544249769
-
Long term low dose 5-fluorouracil in advanced measurable colon cancer: No correlation between toxicity and efficacy
-
abstr
-
Leichman, L., Leichman, C.G., Kinzie, J., Weaver, D., Evans, L.: Long term low dose 5-fluorouracil in advanced measurable colon cancer: no correlation between toxicity and efficacy. Proc. Am. Soc. Clin. Oncol. 4:86, 1985 (abstr)
-
(1985)
Proc. Am. Soc. Clin. Oncol.
, vol.4
, pp. 86
-
-
Leichman, L.1
Leichman, C.G.2
Kinzie, J.3
Weaver, D.4
Evans, L.5
-
30
-
-
0345474028
-
Continuous low dose 5-fluorouracil for adenocarcinoma: Confirmation of activity
-
abstr
-
Belt, R.I., Davidven, M.L., Myron, M.C., Barrett, S.: Continuous low dose 5-fluorouracil for adenocarcinoma: confirmation of activity. Proc. Am. Soc. Clin. Oncol. 4:90, 1985 (abstr)
-
(1985)
Proc. Am. Soc. Clin. Oncol.
, vol.4
, pp. 90
-
-
Belt, R.I.1
Davidven, M.L.2
Myron, M.C.3
Barrett, S.4
-
31
-
-
15644380221
-
Continuous systemic 5-fluorouracil infusion in advanced colorectal cancer: Results in 91 patients
-
abstr
-
Hansen, R., Quebbeman, E., Ausman, R., Frick, J., Ritch, P., Schulte, W., Haas, C., Beatty, P., Anderson, T.: Continuous systemic 5-fluorouracil infusion in advanced colorectal cancer: results in 91 patients. J. Surg. Oncol. 7:94, 1988 (abstr)
-
(1988)
J. Surg. Oncol.
, vol.7
, pp. 94
-
-
Hansen, R.1
Quebbeman, E.2
Ausman, R.3
Frick, J.4
Ritch, P.5
Schulte, W.6
Haas, C.7
Beatty, P.8
Anderson, T.9
-
32
-
-
2642651710
-
Continuous ambulatory infusional 5-fluorouracil chemotherapy in advanced colorectal cancer: A single institutional retrospective study
-
abstr
-
Kuo, S., Finck, S., Cho, J., Glenn, D., Wong, S., Billups, T., Slater, L., Cohen, A., Armentrout, S.: Continuous ambulatory infusional 5-fluorouracil chemotherapy in advanced colorectal cancer: a single institutional retrospective study. Proc. Am. Soc. Clin. Oncol. 8:126, 1989 (abstr)
-
(1989)
Proc. Am. Soc. Clin. Oncol.
, vol.8
, pp. 126
-
-
Kuo, S.1
Finck, S.2
Cho, J.3
Glenn, D.4
Wong, S.5
Billups, T.6
Slater, L.7
Cohen, A.8
Armentrout, S.9
-
33
-
-
33847423025
-
Reversal of palmar plantar erythrodysesthesia by B6 without loss of response in colon cancer patients receiving 200 mg/m/d continuous infusion 5-FU
-
abstr
-
Molina, R., Fabian, C., Slavik, M., Dahlberg, S.: Reversal of palmar plantar erythrodysesthesia by B6 without loss of response in colon cancer patients receiving 200 mg/m/d continuous infusion 5-FU. Proc. Am. Soc. Clin. Oncol. 6:74, 1987 (abstr)
-
(1987)
Proc. Am. Soc. Clin. Oncol.
, vol.6
, pp. 74
-
-
Molina, R.1
Fabian, C.2
Slavik, M.3
Dahlberg, S.4
-
34
-
-
0007552379
-
Prolonged venous infusion of 5-fluorouracil for metastatic cancer: A followup report
-
abstr
-
Wade, J.L., Herbst, S., Greenberg, A.: Prolonged venous infusion of 5-fluorouracil for metastatic cancer: a followup report. Proc. Am. Soc. Clin. Oncol. 7:94, 1988 (abstr)
-
(1988)
Proc. Am. Soc. Clin. Oncol.
, vol.7
, pp. 94
-
-
Wade, J.L.1
Herbst, S.2
Greenberg, A.3
-
35
-
-
0024539308
-
A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: A Mid-Atlantic Oncology Program study
-
Lokich, J.J., Ahlgren, J.D., Gullo, J.J., Philips, J.A., Fryer, J.G.: A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program study. J. Clin. Oncol. 7:425, 1989
-
(1989)
J. Clin. Oncol.
, vol.7
, pp. 425
-
-
Lokich, J.J.1
Ahlgren, J.D.2
Gullo, J.J.3
Philips, J.A.4
Fryer, J.G.5
-
36
-
-
34547388211
-
A randomized trial of continuous systemic infusion (SI) versus bolus therapy (B) with 5-fluorouracil (5-FU) in metastatic measurable colorectal cancer (MCC)
-
abstr
-
Weinerman, B., Stfah, A., Fields, A., Kerr, I., Cripps, C., Shepherd, F., Wierzbicki, R., Temple, W., Maroun, J., Bogues, W., Pater, J.: A randomized trial of continuous systemic infusion (SI) versus bolus therapy (B) with 5-fluorouracil (5-FU) in metastatic measurable colorectal cancer (MCC). Proc. Am. Soc. Clin. Oncol. 9:102, 1990 (abstr)
-
(1990)
Proc. Am. Soc. Clin. Oncol.
, vol.9
, pp. 102
-
-
Weinerman, B.1
Stfah, A.2
Fields, A.3
Kerr, I.4
Cripps, C.5
Shepherd, F.6
Wierzbicki, R.7
Temple, W.8
Maroun, J.9
Bogues, W.10
Pater, J.11
-
37
-
-
0001567830
-
End results of a multicentric randomized trial comparing 5-FU in continuous infusion systemic infusion (CI) to bolus administration (B) in measurable metastatic colorectal cancer
-
abstr
-
Rougler, P., Paillot, B., Laplanche, A., Morvan, F., Benhamed M., Seitj, J.F., Laplaige, P., Jacob, J., Grandjouau, S., Pinon, G.N.: End results of a multicentric randomized trial comparing 5-FU in continuous infusion systemic infusion (CI) to bolus administration (B) in measurable metastatic colorectal cancer. Proc. Am. Soc. Clin. Oncol. 11:163, 1992 (abstr)
-
(1992)
Proc. Am. Soc. Clin. Oncol.
, vol.11
, pp. 163
-
-
Rougler, P.1
Paillot, B.2
Laplanche, A.3
Morvan, F.4
Benhamed, M.5
Seitj, J.F.6
Laplaige, P.7
Jacob, J.8
Grandjouau, S.9
Pinon, G.N.10
-
38
-
-
0342434036
-
A phase III trial of bolus 5-FU versus protracted infusion 5-FU +/-cisplatin in metastatic colorectal cancer
-
abstr
-
Hansen, R., Ryan, L., Anderson, T., Quebbeman, E., Haller, D.: A phase III trial of bolus 5-FU versus protracted infusion 5-FU +/-cisplatin in metastatic colorectal cancer. Proc. Am. Soc. Clin. Oncol. 11:171, 1992 (abstr)
-
(1992)
Proc. Am. Soc. Clin. Oncol.
, vol.11
, pp. 171
-
-
Hansen, R.1
Ryan, L.2
Anderson, T.3
Quebbeman, E.4
Haller, D.5
-
39
-
-
0029012118
-
Phase II study of fluorouracil and its modulation in advanced colorectal cancer: A Southwest
-
Leichman, C.G., Fleming, T.R., Muggia, F.M., Tangen, C.M., Ardalan, B., Doroshow, J.H., Meyers, F.J., Holcombe, R.F., Weiss, G.R., Mangalik, A., Macdonald, J.S.: Phase II study of fluorouracil and its modulation in advanced colorectal cancer: a Southwest Oncology Group study. J. Clin. Oncol. 3:1303, 1995
-
(1995)
Oncology Group Study. J. Clin. Oncol.
, vol.3
, pp. 1303
-
-
Leichman, C.G.1
Fleming, T.R.2
Muggia, F.M.3
Tangen, C.M.4
Ardalan, B.5
Doroshow, J.H.6
Meyers, F.J.7
Holcombe, R.F.8
Weiss, G.R.9
Mangalik, A.10
Macdonald, J.S.11
-
41
-
-
0023876379
-
Circadian varying plasma concentration of 5-fluorouracil during 5-day continuous venous infusion at constant rate in cancer patients
-
Petit, E., Milanci, G., Levi, F., Thyss, A., Bailleul, F., Schneider, M.: Circadian varying plasma concentration of 5-fluorouracil during 5-day continuous venous infusion at constant rate in cancer patients. Cancer Res. 45:1676, 1988
-
(1988)
Cancer Res.
, vol.45
, pp. 1676
-
-
Petit, E.1
Milanci, G.2
Levi, F.3
Thyss, A.4
Bailleul, F.5
Schneider, M.6
-
42
-
-
0025058867
-
Relationship between dihydropyrimidine dehydrogenasc activity and plasma 5-fluorouracil levels: Evidence for circadian variation of plasma drug levels in patients receiving 5-fluorouracil by protracted continuous infusion
-
Harris, B., Song, R., Soong, S., Diasio, R.B.: Relationship between dihydropyrimidine dehydrogenasc activity and plasma 5-fluorouracil levels: evidence for circadian variation of plasma drug levels in patients receiving 5-fluorouracil by protracted continuous infusion. Cancer Res. 56:197, 1990
-
(1990)
Cancer Res.
, vol.56
, pp. 197
-
-
Harris, B.1
Song, R.2
Soong, S.3
Diasio, R.B.4
-
43
-
-
15644377760
-
Circadian rhythm of rat liver dihydropyrimidine dehydrogenase
-
Harris, B.E., Song., R., He, Y.J., Soong, S.J., DiAsio, R.B.: Circadian rhythm of rat liver dihydropyrimidine dehydrogenase. Biochem. Pharmacol. 37:41, 1588
-
(1588)
Biochem. Pharmacol.
, vol.37
, pp. 41
-
-
Harris, B.E.1
Song, R.2
He, Y.J.3
Soong, S.J.4
DiAsio, R.B.5
-
44
-
-
0027392924
-
Circadian rhythm of orotate phosphoribosyl transferase, pyrimidine nucleoside phosphorylase and dihydrouracil dehydrogenase in mouse liver
-
Nagnib, F.M., Soong, S.J., Louni, M.H.: Circadian rhythm of orotate phosphoribosyl transferase, pyrimidine nucleoside phosphorylase and dihydrouracil dehydrogenase in mouse liver. Biochem. Pharmacol. 45:667, 1993
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 667
-
-
Nagnib, F.M.1
Soong, S.J.2
Louni, M.H.3
-
45
-
-
0344043062
-
Programmable-in-time pumps for chromotherapy of patients with colorectal cancer with 5-day circadian-modulated venous infusion of 5-fluorouracil
-
abstr
-
Levi, F., Soussain, A., Adam, R., Caussanel, J., Metzger, G., Misset, J.L.: Programmable-in-time pumps for chromotherapy of patients with colorectal cancer with 5-day circadian-modulated venous infusion of 5-fluorouracil. Proc. Am. Soc. Clin. Oncol. 8:429, 1989 (abstr)
-
(1989)
Proc. Am. Soc. Clin. Oncol.
, vol.8
, pp. 429
-
-
Levi, F.1
Soussain, A.2
Adam, R.3
Caussanel, J.4
Metzger, G.5
Misset, J.L.6
-
46
-
-
0027332756
-
Phase I study of 5-fluorouracil and leucovorin by a 14-day circadian infusion in metastatic adenocarcinoma patients
-
Bjarnason, G.A., Kerr, I.G., Doyle, N., Macdonald, M., Sone, M.: Phase I study of 5-fluorouracil and leucovorin by a 14-day circadian infusion in metastatic adenocarcinoma patients. Cancer Chemother. Pharmacol. 33:221, 1993
-
(1993)
Cancer Chemother. Pharmacol.
, vol.33
, pp. 221
-
-
Bjarnason, G.A.1
Kerr, I.G.2
Doyle, N.3
Macdonald, M.4
Sone, M.5
-
47
-
-
0026512446
-
A chronopharmacologic phase II clinical trial with 5-fluorouracil, folinic acid and oxaliplatin using an ambulatory multichannel programmable pump
-
Levi, F., Misset, J.L., Brienza, S., Adam, R., Metzger, G., Itzakhi, M., Caussanel, J.P., Kunstlinger, F., Lecouturier, S., Descorps-Declere, A., Jasmin, C., Bismuth, H., Reinberg, A.: A chronopharmacologic phase II clinical trial with 5-fluorouracil, folinic acid and oxaliplatin using an ambulatory multichannel programmable pump. Cancer 69:893, 1992
-
(1992)
Cancer
, vol.69
, pp. 893
-
-
Levi, F.1
Misset, J.L.2
Brienza, S.3
Adam, R.4
Metzger, G.5
Itzakhi, M.6
Caussanel, J.P.7
Kunstlinger, F.8
Lecouturier, S.9
Descorps-Declere, A.10
Jasmin, C.11
Bismuth, H.12
Reinberg, A.13
-
48
-
-
0026096125
-
Biochemical modulation: A modality that has come of therapeutic age
-
Allegra, C.J.: Biochemical modulation: a modality that has come of therapeutic age. J. Clin. Oncol. 9:1723, 1991
-
(1991)
J. Clin. Oncol.
, vol.9
, pp. 1723
-
-
Allegra, C.J.1
-
49
-
-
0027980010
-
Preclinical and clinical aspects of biomodulation of 5-fluorouracil
-
Sotos, G.A., Grogan, L., Allegra, C.J.: Preclinical and clinical aspects of biomodulation of 5-fluorouracil. Cancer Treat. Rev. 20:11, 1994
-
(1994)
Cancer Treat. Rev.
, vol.20
, pp. 11
-
-
Sotos, G.A.1
Grogan, L.2
Allegra, C.J.3
-
50
-
-
0002548405
-
5-Fluoropyrimidines
-
B.A. Chabner, D.L. Longo, editors. Philadelphia, Lippincott-Raven
-
Grem, J.: 5-Fluoropyrimidines. In Cancer Chemotherapy and Biotherapy, Principles and Practice (2nd ed.), B.A. Chabner, D.L. Longo, editors. Philadelphia, Lippincott-Raven, 1996, pp. 140-211
-
(1996)
Cancer Chemotherapy and Biotherapy, Principles and Practice (2nd Ed.)
, pp. 140-211
-
-
Grem, J.1
-
51
-
-
0021130547
-
Phase I-II trial of high dose calcium leucovorin and 5-fluorouracil in advanced colorectal cancer
-
Madajewicz, S., Petrelli, N., Rustwn, Y., Carnnbell, J., Herrera, L., Mittelman, A., Perry, A., Creaven, P.: Phase I-II trial of high dose calcium leucovorin and 5-fluorouracil in advanced colorectal cancer. Cancer Res. 44:4667, 1984
-
(1984)
Cancer Res.
, vol.44
, pp. 4667
-
-
Madajewicz, S.1
Petrelli, N.2
Rustwn, Y.3
Carnnbell, J.4
Herrera, L.5
Mittelman, A.6
Perry, A.7
Creaven, P.8
-
52
-
-
0022624346
-
Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high dose folinic acid
-
Machover, D., Goldschmidt, E., Chollet, P., Metzger, G., Zittoun, J. Marquet, J., Vandenbulcke, J-M., Misset, J-L., Schwarzenberg, L., Fourtillan, J.B., Gaget, H., Mathd, G.: Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high dose folinic acid. J. Clin. Oncol. 4:685, 1986
-
(1986)
J. Clin. Oncol.
, vol.4
, pp. 685
-
-
Machover, D.1
Goldschmidt, E.2
Chollet, P.3
Metzger, G.4
Zittoun, J.5
Marquet, J.6
Vandenbulcke, J.-M.7
Misset, J.-L.8
Schwarzenberg, L.9
Fourtillan, J.B.10
Gaget, H.11
Mathd, G.12
-
53
-
-
84909847981
-
An efficient leucovorin and 5-fluorouracil sequence: Dose escalation and pharmacological monitoring
-
abstr
-
Bruckner, H., Ruboz, J., Spiegelman, M.: An efficient leucovorin and 5-fluorouracil sequence: dose escalation and pharmacological monitoring. Proc A.A.C.R. 24:547, 1983 (abstr)
-
(1983)
Proc A.A.C.R.
, vol.24
, pp. 547
-
-
Bruckner, H.1
Ruboz, J.2
Spiegelman, M.3
-
54
-
-
15644366012
-
High-dose leucovorin and 5-fluorouracil in refractory and relapsed colorectal carcinoma
-
abstr
-
Zakem, M., Hines, J.D., Adelstein, D.J., Rustiun, Y.M.: High-dose leucovorin and 5-fluorouracil in refractory and relapsed colorectal carcinoma. Proc. Am. Soc. Clin. Oncol. 5:81, 1986 (abstr)
-
(1986)
Proc. Am. Soc. Clin. Oncol.
, vol.5
, pp. 81
-
-
Zakem, M.1
Hines, J.D.2
Adelstein, D.J.3
Rustiun, Y.M.4
-
55
-
-
84912815872
-
Therapeutic efficacy of the combination of 5-fluorouracil and high-dose leucovorin in patients with advanced colorectal carcinoma: Single daily intravenous dose for five days
-
H.W. Bruckner, Y.N. Rusturn, editors. New York, Park Row Publishers
-
Bruckner, H., Ruboz, T., Spiegehnan, M., Ambinder, E., Hart, R., Holland, J.F.: Therapeutic efficacy of the combination of 5-fluorouracil and high-dose leucovorin in patients with advanced colorectal carcinoma: single daily intravenous dose for five days. In The Current Status of 5-Fluorouracil Leucovorin Combination, H.W. Bruckner, Y.N. Rusturn, editors. New York, Park Row Publishers, 1984
-
(1984)
The Current Status of 5-Fluorouracil Leucovorin Combination
-
-
Bruckner, H.1
Ruboz, T.2
Spiegehnan, M.3
Ambinder, E.4
Hart, R.5
Holland, J.F.6
-
56
-
-
0023149481
-
5-Fluorouracil and folinic acid in the treatment of metastatic colorectal cancer: A randomized comparison: a Southwest Oncoloey Group study
-
Budd, G.T., Fleming, T.R., Bukowski, R.M., MeCracken, J.D., Rivkin, S.E., O'Bryan, R.M., Balcerzak, S.P., Macdonald, J.S.: 5-Fluorouracil and folinic acid in the treatment of metastatic colorectal cancer: a randomized comparison: a Southwest Oncoloey Group study. J. Clin. Oncol. 5:272, 1987
-
(1987)
J. Clin. Oncol.
, vol.5
, pp. 272
-
-
Budd, G.T.1
Fleming, T.R.2
Bukowski, R.M.3
Mecracken, J.D.4
Rivkin, S.E.5
O'Bryan, R.M.6
Balcerzak, S.P.7
Macdonald, J.S.8
-
57
-
-
0022510320
-
High-dose continuous infusion folinic acid and bolus 5-fluorouracil in patients with advanced colorectal cancer: A phase II study
-
Bertrand, M., Doroshow, J.H., Multhauf, P., Blayney, D.W., Carr, B.I., Cecchi, G., Goldberg, D., Leong, L., Margolin, K., Metter, G., Staples, R.: High-dose continuous infusion folinic acid and bolus 5-fluorouracil in patients with advanced colorectal cancer: a phase II study. J. Clin. Oncol. 4:1058, 1986
-
(1986)
J. Clin. Oncol.
, vol.4
, pp. 1058
-
-
Bertrand, M.1
Doroshow, J.H.2
Multhauf, P.3
Blayney, D.W.4
Carr, B.I.5
Cecchi, G.6
Goldberg, D.7
Leong, L.8
Margolin, K.9
Metter, G.10
Staples, R.11
-
58
-
-
0021677896
-
5-Fluorouracil and folinic acid: A phase I-II trial in gastrointestinal malignancy
-
Cunningham, J., Bukowski, R.M., Budd, G.T., Weick, J.K., Purvis, J.: 5-Fluorouracil and folinic acid: a phase I-II trial in gastrointestinal malignancy. Invest. New Drugs 2:291, 1984
-
(1984)
Invest. New Drugs
, vol.2
, pp. 291
-
-
Cunningham, J.1
Bukowski, R.M.2
Budd, G.T.3
Weick, J.K.4
Purvis, J.5
-
59
-
-
0009604372
-
Combined 5-fluorouracil infusion and high-dose folinic acid in the treatment of metastatic gastrointestinal cancer
-
Green, H., Desai, A., Levick, S., Tester, W.: Combined 5-fluorouracil infusion and high-dose folinic acid in the treatment of metastatic gastrointestinal cancer. Proc. Am. Soc. Clin. Oncol. 5:89, 1986
-
(1986)
Proc. Am. Soc. Clin. Oncol.
, vol.5
, pp. 89
-
-
Green, H.1
Desai, A.2
Levick, S.3
Tester, W.4
-
60
-
-
0023874456
-
A randomized trial of fluorouracil and folic acid in patients with metastatic colorectal carcinoma
-
Erlichman, C., Fine, S., Wong, A., Elhakin, T.: A randomized trial of fluorouracil and folic acid in patients with metastatic colorectal carcinoma. J. Clin. Oncol. 6:469, 1988
-
(1988)
J. Clin. Oncol.
, vol.6
, pp. 469
-
-
Erlichman, C.1
Fine, S.2
Wong, A.3
Elhakin, T.4
-
61
-
-
0024385167
-
The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: A prospective randomized phase III trial
-
Petrelli, N., Douglass, H.O., Herrera, L., Russell, D., Stablein, D.M., Bruckner, H.W., Mayer, R.J., Schinella, R., Green, M.D., Muggia, F.M., Megibow, A., Greenwald, E.S., Bukowski, R.M., Harris, J., Levin, B., Gaynor, E., Loutri, A., Kalser, M.H., Barkin, J.S., Benedetto, P., Woolley, P.V., Nauta, R., Weaver, D.W., Leichman, L.P. (Gastrointestinal Tumor Study Group): The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: a prospective randomized phase III trial. J. Clin. Oncol. 7:1419, 1989
-
(1989)
J. Clin. Oncol.
, vol.7
, pp. 1419
-
-
Petrelli, N.1
Douglass, H.O.2
Herrera, L.3
Russell, D.4
Stablein, D.M.5
Bruckner, H.W.6
Mayer, R.J.7
Schinella, R.8
Green, M.D.9
Muggia, F.M.10
Megibow, A.11
Greenwald, E.S.12
Bukowski, R.M.13
Harris, J.14
Levin, B.15
Gaynor, E.16
Loutri, A.17
Kalser, M.H.18
Barkin, J.S.19
Benedetto, P.20
Woolley, P.V.21
Nauta, R.22
Weaver, D.W.23
Leichman, L.P.24
more..
-
62
-
-
0024347268
-
Biochemical modulation of fluorouracil: Evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma
-
Poon, M.A., O'Connell, M.J., Moertel, C.G., Wieand, H.S., Cullinau, S.A., Everson, L.K., Krook, J.E., Mailliard, J.A., Laurie, J.A., Tschetter, L.K., Wiesenfield, M.: Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma. J. Clin. Oncol. 7:1407, 1989
-
(1989)
J. Clin. Oncol.
, vol.7
, pp. 1407
-
-
Poon, M.A.1
O'Connell, M.J.2
Moertel, C.G.3
Wieand, H.S.4
Cullinau, S.A.5
Everson, L.K.6
Krook, J.E.7
Mailliard, J.A.8
Laurie, J.A.9
Tschetter, L.K.10
Wiesenfield, M.11
-
63
-
-
0026721532
-
Modulation of fluorouracil by leucovorin in advanced colorectal cancer
-
Piedbois, P., Buyse, M., Rustum, Y., Machover, D., Erlichman, C., Carlson, R.W., Valone, F., Labianca, R., Doroshow, J.H., Petrelli, N.: Modulation of fluorouracil by leucovorin in advanced colorectal cancer. J. Clin. Oncol. 10:896, 1992
-
(1992)
J. Clin. Oncol.
, vol.10
, pp. 896
-
-
Piedbois, P.1
Buyse, M.2
Rustum, Y.3
Machover, D.4
Erlichman, C.5
Carlson, R.W.6
Valone, F.7
Labianca, R.8
Doroshow, J.H.9
Petrelli, N.10
-
64
-
-
0023520170
-
A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colordctal carcinoma
-
Petrelli, N., Herrera, L., Rustum, Y., Burke, P., Creaven, P., Stulc, J., Enuich, L.J., Mitte, A.: A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colordctal carcinoma. J. Clin. Oncol. 5:1559, 1987
-
(1987)
J. Clin. Oncol.
, vol.5
, pp. 1559
-
-
Petrelli, N.1
Herrera, L.2
Rustum, Y.3
Burke, P.4
Creaven, P.5
Stulc, J.6
Enuich, L.J.7
Mitte, A.8
-
65
-
-
0024342059
-
Treatment of patients with advanced colorectal carcinomas with fluorouracil alone, high-dose leucovorin plus fluorouracil or sequential methotrexate, fluorouracil and leucovorin: A randomized trial of the Northern California Oncology Group
-
Valone, F.H., Friedman, M.A., Wittlinger, P.S., Drakes, T., Eisenberg, P.D., Malec, M., Hannigan, J.F., Brown, B.W.: Treatment of patients with advanced colorectal carcinomas with fluorouracil alone, high-dose leucovorin plus fluorouracil or sequential methotrexate, fluorouracil and leucovorin: a randomized trial of the Northern California Oncology Group. J. Clin. Oncol. 7:1427, 1989
-
(1989)
J. Clin. Oncol.
, vol.7
, pp. 1427
-
-
Valone, F.H.1
Friedman, M.A.2
Wittlinger, P.S.3
Drakes, T.4
Eisenberg, P.D.5
Malec, M.6
Hannigan, J.F.7
Brown, B.W.8
-
66
-
-
0025261244
-
Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy
-
Doroshow, J.H., Mulhart, P., Leong, L., Margolin, K., Litchfield, T., Akrnan, S., Carr, B., Mertraud, M., Goldberg, D., Blayney, D., Odujinrin, O., DeLap, R., Shuoter, J., Newman, E.: Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy. J. Clin. Oncol. 8:491, 1990
-
(1990)
J. Clin. Oncol.
, vol.8
, pp. 491
-
-
Doroshow, J.H.1
Mulhart, P.2
Leong, L.3
Margolin, K.4
Litchfield, T.5
Akrnan, S.6
Carr, B.7
Mertraud, M.8
Goldberg, D.9
Blayney, D.10
Odujinrin, O.11
DeLap, R.12
Shuoter, J.13
Newman, E.14
-
67
-
-
0026662471
-
Randomized comparison of weekly bolus 5-fluorouracil with or without leucovorin in metastatic colorectal carcinoma
-
Nobile, M.T., Rosso, R., Sertoli, M.R., Rubagotti, A., Vidili, M.G., Guglielmi, A., Venturini. M., Canobbio, L., Fassio, T., Gallo, L., Galligioni, E., Gallotti, P., Bruzzi, P., Sobrero, A.: Randomized comparison of weekly bolus 5-fluorouracil with or without leucovorin in metastatic colorectal carcinoma. Eur. J. Cancer 28A:1823, 1992
-
(1992)
Eur. J. Cancer
, vol.28 A
, pp. 1823
-
-
Nobile, M.T.1
Rosso, R.2
Sertoli, M.R.3
Rubagotti, A.4
Vidili, M.G.5
Guglielmi, A.6
Venturini, M.7
Canobbio, L.8
Fassio, T.9
Gallo, L.10
Galligioni, E.11
Gallotti, P.12
Bruzzi, P.13
Sobrero, A.14
-
68
-
-
0027408915
-
Prolonged continuous infusion of fluorouracil with weekly bolus leucovorin: A phase II study in patients with disseminated colorectal cancer
-
Leichman, C.G., Leichman, L., Spears, C.P., Rosen, P.J., Jeffers, S., Groshen, S.: Prolonged continuous infusion of fluorouracil with weekly bolus leucovorin: a phase II study in patients with disseminated colorectal cancer. J. Natl. Cancer Inst. 85:41, 1993
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 41
-
-
Leichman, C.G.1
Leichman, L.2
Spears, C.P.3
Rosen, P.J.4
Jeffers, S.5
Groshen, S.6
-
69
-
-
0005048002
-
A phase II trial of protracted therapy with 5-fluorouracil and daily leucovorin in metastatic colorectal cancer
-
Tempero, M., Berg, A., Block, M., Hutchins, M., Moravec, D., Langdon, R.: A phase II trial of protracted therapy with 5-fluorouracil and daily leucovorin in metastatic colorectal cancer. J. Infus. Chemother. 4:112, 1994
-
(1994)
J. Infus. Chemother.
, vol.4
, pp. 112
-
-
Tempero, M.1
Berg, A.2
Block, M.3
Hutchins, M.4
Moravec, D.5
Langdon, R.6
-
70
-
-
0020965434
-
Sequential methotrexate and 5-fluorouracil: Mechanisms of synergy
-
Bertino, J.R., Mini, E., Fernandez, DJ.: Sequential methotrexate and 5-fluorouracil: mechanisms of synergy. Semin. Oncol. 10(2):2, 1983
-
(1983)
Semin. Oncol.
, vol.10
, Issue.2
, pp. 2
-
-
Bertino, J.R.1
Mini, E.2
Fernandez, D.J.3
-
71
-
-
0017361019
-
Scheduledependent antitumor effects of methotrexate and 5 fluorouracil
-
Bertino, J.R., Sawicki, W.L., Lindqudst, C.A., Gupta, V.S.: Scheduledependent antitumor effects of methotrexate and 5 fluorouracil. Cancer Res. 37:327, 1977
-
(1977)
Cancer Res.
, vol.37
, pp. 327
-
-
Bertino, J.R.1
Sawicki, W.L.2
Lindqudst, C.A.3
Gupta, V.S.4
-
72
-
-
15644365070
-
-
Washington DC, American Society for Microbiology
-
Isacoff, W.H., Nagel, G., Heunnekens, F.M., Wihnanns, W., Cadman, E., Cano, J.P., Diehl, V., Bertino, J.R.: Methotrexate Symposium: Proceedings of the 11th International Congress of Chemotherapy and the 19th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington DC, American Society for Microbiology, 1979, pp. 1475-1484
-
(1979)
Methotrexate Symposium: Proceedings of the 11th International Congress of Chemotherapy and the 19th Interscience Conference on Antimicrobial Agents and Chemotherapy
, pp. 1475-1484
-
-
Isacoff, W.H.1
Nagel, G.2
Heunnekens, F.M.3
Wihnanns, W.4
Cadman, E.5
Cano, J.P.6
Diehl, V.7
Bertino, J.R.8
-
73
-
-
0027351189
-
Ode to methotrexate
-
Bektino, J.R.: Ode to methotrexate. J. Clin. Oncol. 11:5, 1993
-
(1993)
J. Clin. Oncol.
, vol.11
, pp. 5
-
-
Bektino, J.R.1
-
74
-
-
0022262215
-
Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates
-
Allegra, C.J., Chabner, B.A., Drake, J.C., Lutz, R., Rodbard, D., Jolivet, J.: Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates. Biol. Chem. 260:9720, 1985
-
(1985)
Biol. Chem.
, vol.260
, pp. 9720
-
-
Allegra, C.J.1
Chabner, B.A.2
Drake, J.C.3
Lutz, R.4
Rodbard, D.5
Jolivet, J.6
-
75
-
-
0016634038
-
Stoichiometric inhibition of mammalian dihydrofolate reductase by the α-glytaniyl metabolite of methotrcxatc 4-amino-4-deoxy-M-10-methyl-pteroyl-glutamyl-α-glutamate
-
Jacobs, S.A., Adwnson, R.H., Chabner, B.A., Deff, C.J., Johns, D.G.: Stoichiometric inhibition of mammalian dihydrofolate reductase by the α-glytaniyl metabolite of methotrcxatc 4-amino-4-deoxy-M-10-methyl-pteroyl-glutamyl-α-glutamate. Biochem. Biophys. Res. Commun. 634:692, 1975
-
(1975)
Biochem. Biophys. Res. Commun.
, vol.634
, pp. 692
-
-
Jacobs, S.A.1
Adwnson, R.H.2
Chabner, B.A.3
Deff, C.J.4
Johns, D.G.5
-
76
-
-
0018700143
-
Enhanced 5-fluorouracil nucleotide formation after methotrexate administration: Explanation for drug synergism
-
Cadman, E.D., Heimer, R., Davis, L.: Enhanced 5-fluorouracil nucleotide formation after methotrexate administration: explanation for drug synergism. Science 205:1135, 1979
-
(1979)
Science
, vol.205
, pp. 1135
-
-
Cadman, E.D.1
Heimer, R.2
Davis, L.3
-
77
-
-
0020963765
-
MTX/5-FU trials in gastrointestinal and other cancers
-
C.H.
-
Bruckner, H.W., C.H.: MTX/5-FU trials in gastrointestinal and other cancers. Semin. Oncol. 10(2):32, 1983
-
(1983)
Semin. Oncol.
, vol.10
, Issue.2
, pp. 32
-
-
Bruckner, H.W.1
-
78
-
-
0018420139
-
Treatment of advanced colorectal carcinoma with high-dose methotrexate given alone and in combination with 5-fluorouracil
-
Isacoff, W.H., Tisman, G., Block, J.B.: Treatment of advanced colorectal carcinoma with high-dose methotrexate given alone and in combination with 5-fluorouracil. Proc. A.A.C.R. 20:381, 1979
-
(1979)
Proc. A.A.C.R.
, vol.20
, pp. 381
-
-
Isacoff, W.H.1
Tisman, G.2
Block, J.B.3
-
79
-
-
0024414365
-
Superiority of sequential methotrexate, fluorouracil, and leucovorin to fluorouracil alone in advanced symptomatic eolorectal carcinoma: A randomized trial
-
Nordic Gastrointestinal Tumor Adjuvant Therapy Group: Superiority of sequential methotrexate, fluorouracil, and leucovorin to fluorouracil alone in advanced symptomatic eolorectal carcinoma: a randomized trial. J. Clin. Oncol. 7:14, 1989
-
(1989)
J. Clin. Oncol.
, vol.7
, pp. 14
-
-
-
80
-
-
0026100241
-
The influence of drug interval on the effect of methotrexate and fluorouracil in the treatment of advanced colorectal cancer
-
Marsh, J.C., Bertino, J.P., Katz, K.H., Davis, C.A., Durivage, H.J., Rome, L.S., Richards, F., Capizzi, R.L., Farber, L.R., Pasquale, D.N., Stuart, R., Koletsky, A.J., Makuch, R., O'Hollaren, K.: The influence of drug interval on the effect of methotrexate and fluorouracil in the treatment of advanced colorectal cancer. J. Clin. Oncol. 99:371, 1991
-
(1991)
J. Clin. Oncol.
, vol.99
, pp. 371
-
-
Marsh, J.C.1
Bertino, J.P.2
Katz, K.H.3
Davis, C.A.4
Durivage, H.J.5
Rome, L.S.6
Richards, F.7
Capizzi, R.L.8
Farber, L.R.9
Pasquale, D.N.10
Stuart, R.11
Koletsky, A.J.12
Makuch, R.13
O'Hollaren, K.14
-
81
-
-
0022641824
-
1. Sequential methotrexate-5-FU-leucovorin (MVL) in advanced colorectal cancer
-
Glimelius, B., Gimnau, C., Graffinan, S., Pahlrnan, L., Stahle, E.: 1. Sequential methotrexate-5-FU-leucovorin (MVL) in advanced colorectal cancer. Eur. J. Cancer Oncol. 22:295, 1986
-
(1986)
Eur. J. Cancer Oncol.
, vol.22
, pp. 295
-
-
Glimelius, B.1
Gimnau, C.2
Graffinan, S.3
Pahlrnan, L.4
Stahle, E.5
-
82
-
-
0026006962
-
Biochemical modulation of fluorouracil with leucovorin: Confirmatory evidence of improved therapeutic efficacy in advanced colorectal cancer
-
Poon, M.A., O'Connell, M.J., Wieand, H.S., Krook, J.E., Gerstner, J.B., Tschetter, L.K., Levitt, R., Kardinal, C.G., Mailliard, J.A.: Biochemical modulation of fluorouracil with leucovorin: confirmatory evidence of improved therapeutic efficacy in advanced colorectal cancer. J. Clin. Oncol. 9:1967, 1991
-
(1991)
J. Clin. Oncol.
, vol.9
, pp. 1967
-
-
Poon, M.A.1
O'Connell, M.J.2
Wieand, H.S.3
Krook, J.E.4
Gerstner, J.B.5
Tschetter, L.K.6
Levitt, R.7
Kardinal, C.G.8
Mailliard, J.A.9
-
83
-
-
0028219974
-
Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer
-
Piedbois, P., Buyse, M., Blijham, G., Glimelius, B., Herrmann, R., Valone, F., Carlson, R., Machiavelli, M., Delfino, C., Abad, A., Petrelli, N.: Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer. J. Clin. Oncol. 12:960, 1994
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 960
-
-
Piedbois, P.1
Buyse, M.2
Blijham, G.3
Glimelius, B.4
Herrmann, R.5
Valone, F.6
Carlson, R.7
Machiavelli, M.8
Delfino, C.9
Abad, A.10
Petrelli, N.11
-
84
-
-
0023718558
-
Interferon effect upon the adenocarcinoma 38 and HL-60 cell lines: Antiproliferative responses and synergistic interactions with halogenated pyrimidine antimetabolites
-
Elias, L., Crissman, H.A.: Interferon effect upon the adenocarcinoma 38 and HL-60 cell lines: antiproliferative responses and synergistic interactions with halogenated pyrimidine antimetabolites. Cancer Res. 48:4868, 1988
-
(1988)
Cancer Res.
, vol.48
, pp. 4868
-
-
Elias, L.1
Crissman, H.A.2
-
85
-
-
0024414582
-
Interferon effects upon fuorouracil metabolism by HL-60 cells
-
Elias, L., Sandoval, J.M.: Interferon effects upon fuorouracil metabolism by HL-60 cells. Biochem. Biophys. Res. Commun. 163:867, 1989
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.163
, pp. 867
-
-
Elias, L.1
Sandoval, J.M.2
-
86
-
-
0025043811
-
Interaction of α-interferon and 5-fluorouracil in H630 human colon carcinoma cell line
-
Chu, E., Zinn, S., Boarman, D., Allegra, C.J.: Interaction of α-interferon and 5-fluorouracil in H630 human colon carcinoma cell line. Cancer Res. 50:58340, 1990
-
(1990)
Cancer Res.
, vol.50
, pp. 58340
-
-
Chu, E.1
Zinn, S.2
Boarman, D.3
Allegra, C.J.4
-
87
-
-
0026554769
-
Biochemical modulation of fluorouracil with leucovorin and interferon: Preclinical and clinical investigations
-
Grem, J.L., Chu, E., Boarman, D., Balls, F., Murphy, R.F., McAtee, N., Allegra, C.J.: Biochemical modulation of fluorouracil with leucovorin and interferon: preclinical and clinical investigations. Semin. Oncol. 19:366, 1992
-
(1992)
Semin. Oncol.
, vol.19
, pp. 366
-
-
Grem, J.L.1
Chu, E.2
Boarman, D.3
Balls, F.4
Murphy, R.F.5
McAtee, N.6
Allegra, C.J.7
-
88
-
-
0025945855
-
Phase II trial of fluorouracil and recombinant interferon alpha-Za in patients with advanced colorectal carcinoma: An Eastern Cooperative Group study
-
Wadler, S., Lembersky, B., Atkins, M., Kirkwood, J., Petrelli, N.: Phase II trial of fluorouracil and recombinant interferon alpha-Za in patients with advanced colorectal carcinoma: an Eastern Cooperative Group study. J. Clin. Oncol. 9:1806, 1991
-
(1991)
J. Clin. Oncol.
, vol.9
, pp. 1806
-
-
Wadler, S.1
Lembersky, B.2
Atkins, M.3
Kirkwood, J.4
Petrelli, N.5
-
89
-
-
0025060896
-
Clinical update on the role of fluorouracil and recombinant interferon alpha-za in the treatment of colorectal carcinoma
-
Wadler, S., Wiernik, P.H.: Clinical update on the role of fluorouracil and recombinant interferon alpha-za in the treatment of colorectal carcinoma. Semin. Oncol. 17(1):16, 1990
-
(1990)
Semin. Oncol.
, vol.17
, Issue.1
, pp. 16
-
-
Wadler, S.1
Wiernik, P.H.2
-
90
-
-
0025606259
-
Phase II study of fluorouracil and recombinant interferon alpha-Za in previously untreated advanced colorectal carcinoma
-
Pazdur, R., Ajani, J.A., Pan, Y.Z., Winn, R., Jackson, D., Shepard, B., DuBrow, R., Campos, L., Quaraishi, M., Faintuch, J., Abbruzzese, J.L., Gutterman, J., Levin, B.: Phase II study of fluorouracil and recombinant interferon alpha-Za in previously untreated advanced colorectal carcinoma. J. Clin. Oncol. 12:2027, 1990
-
(1990)
J. Clin. Oncol.
, vol.12
, pp. 2027
-
-
Pazdur, R.1
Ajani, J.A.2
Pan, Y.Z.3
Winn, R.4
Jackson, D.5
Shepard, B.6
DuBrow, R.7
Campos, L.8
Quaraishi, M.9
Faintuch, J.10
Abbruzzese, J.L.11
Gutterman, J.12
Levin, B.13
-
91
-
-
0026635713
-
Treatment of advanced cold rectal cancer with recombinant interferon alpha and fluorouracil: Activity in liver metastasis
-
Diaz-Rubio, E., Jimeno, J., Camps, C., Aranda, E., Massuti, B., Blanco, E., Anton, A., Lizon, J., Gonzalez-Larriba, J.L.: Treatment of advanced cold rectal cancer with recombinant interferon alpha and fluorouracil: activity in liver metastasis. Cancer Invest. 10:259, 1992
-
(1992)
Cancer Invest.
, vol.10
, pp. 259
-
-
Diaz-Rubio, E.1
Jimeno, J.2
Camps, C.3
Aranda, E.4
Massuti, B.5
Blanco, E.6
Anton, A.7
Lizon, J.8
Gonzalez-Larriba, J.L.9
-
92
-
-
0026513546
-
Alpha-2a interferon and 5-fluorouracil for advanced colorectal carcinoma: The Memorial Sloan Kettering experience
-
Kemeny, M., Younes, A.: Alpha-2a interferon and 5-fluorouracil for advanced colorectal carcinoma: the Memorial Sloan Kettering experience. Semin. Oncol. 19:171, 1992
-
(1992)
Semin. Oncol.
, vol.19
, pp. 171
-
-
Kemeny, M.1
Younes, A.2
-
93
-
-
0025949491
-
A pilot study of interferon alpha-2a in combination with fluorouracil plus high dose leucovorin in metastatic gastrointestinal carcinoma
-
Grem, J.L., McAtee, N., Murphy, R.F., Balis, F.M., Steinberg, S.M., Hamilton, J.M., Sorensen, J.M., Sartor, O., Kramer, B.S., Goldstein, L.J., Gay, L.M., Caubo, K.M., Goldspiel, B.G., Allegra, C.J.: A pilot study of interferon alpha-2a in combination with fluorouracil plus high dose leucovorin in metastatic gastrointestinal carcinoma. J. Clin. Oncol. 9:1811, 1991
-
(1991)
J. Clin. Oncol.
, vol.9
, pp. 1811
-
-
Grem, J.L.1
McAtee, N.2
Murphy, R.F.3
Balis, F.M.4
Steinberg, S.M.5
Hamilton, J.M.6
Sorensen, J.M.7
Sartor, O.8
Kramer, B.S.9
Goldstein, L.J.10
Gay, L.M.11
Caubo, K.M.12
Goldspiel, B.G.13
Allegra, C.J.14
-
94
-
-
0029055178
-
Treatment of advanced colorectal cancer with 5-fluorouracil and Interferon alpha: An overview of clinical trials
-
Raderer, M., Scheithauer, W.: Treatment of advanced colorectal cancer with 5-fluorouracil and Interferon alpha: an overview of clinical trials. Eur. J. Cancer 316:1002, 1995
-
(1995)
Eur. J. Cancer
, vol.316
, pp. 1002
-
-
Raderer, M.1
Scheithauer, W.2
-
95
-
-
0015151785
-
Aspartate transcarbamylase interaction with the transition state analogue N-(phosphoacetyl)-L-aspartate
-
Collins, K.D., Stark, G.R.: Aspartate transcarbamylase interaction with the transition state analogue N-(phosphoacetyl)-L-aspartate. J. Biol. Chem. 246:6599, 1971
-
(1971)
J. Biol. Chem.
, vol.246
, pp. 6599
-
-
Collins, K.D.1
Stark, G.R.2
-
96
-
-
1542669884
-
Improving the antitumor activity of 5-fluorouracil by increasing its incorporation into RNA via metabolic modulation
-
Spiegehnan, S., Sawyer, R., Nayak, R., Ritzi, E., Stolfi, R., Martin, D.: Improving the antitumor activity of 5-fluorouracil by increasing its incorporation into RNA via metabolic modulation. Proc. Natl. Acad. Sci. U.S.A. 77:4966, 1980
-
(1980)
Proc. Natl. Acad. Sci. U.S.A.
, vol.77
, pp. 4966
-
-
Spiegehnan, S.1
Sawyer, R.2
Nayak, R.3
Ritzi, E.4
Stolfi, R.5
Martin, D.6
-
97
-
-
0020621335
-
Therapeutic utility of utilizing low doses of N-(phosphoacetyl)-L-aspartic acid in combination with 5-fluorouracil: A murine study with clinical relevance
-
Martin, D.S., Stolfi, R.L., Saywer, R.C., Spiegehnan, S., Casper, E.S., Young, C.W.: Therapeutic utility of utilizing low doses of N-(phosphoacetyl)-L-aspartic acid in combination with 5-fluorouracil: a murine study with clinical relevance. Cancer Res. 43:2317, 1983
-
(1983)
Cancer Res.
, vol.43
, pp. 2317
-
-
Martin, D.S.1
Stolfi, R.L.2
Saywer, R.C.3
Spiegehnan, S.4
Casper, E.S.5
Young, C.W.6
-
98
-
-
0023917467
-
A randomized phase I and II study of short-term infusion of high-dose fluorouracil with or without N-(phosphoacetyl)-L-aspartic acid in patients with advanced pancreatic and colorectal cancers
-
Ardelan, B., Singh, G., Silberman, H.: A randomized phase I and II study of short-term infusion of high-dose fluorouracil with or without N-(phosphoacetyl)-L-aspartic acid in patients with advanced pancreatic and colorectal cancers. J. Clin. Oncol. 6:1053, 1988
-
(1988)
J. Clin. Oncol.
, vol.6
, pp. 1053
-
-
Ardelan, B.1
Singh, G.2
Silberman, H.3
-
99
-
-
0024992069
-
Phase II study of biochemical modulation of 5-fluorouracil by low-dose PALA in patients with colorectal cancer
-
O'Dwyer, P.J., Paul, A.R., Walczak, J., Weiner, L.M., Litwin, S., Comis, R.L.: Phase II study of biochemical modulation of 5-fluorouracil by low-dose PALA in patients with colorectal cancer. J. Clin. Oncol. 8:1497, 1990
-
(1990)
J. Clin. Oncol.
, vol.8
, pp. 1497
-
-
O'Dwyer, P.J.1
Paul, A.R.2
Walczak, J.3
Weiner, L.M.4
Litwin, S.5
Comis, R.L.6
-
100
-
-
0026763307
-
Biochemical modulation of bolus fluorouracil by PALA in patients with advanced colorectal cancer
-
Kemeny, N., Conti, J.A., Seiter, K., Niedzwiecki, D., Botet, J., Martin, D., Costa, P., Wiseberg, J., McCulloch, W.: Biochemical modulation of bolus fluorouracil by PALA in patients with advanced colorectal cancer. J. Clin. Oncol. 10:747, 1992
-
(1992)
J. Clin. Oncol.
, vol.10
, pp. 747
-
-
Kemeny, N.1
Conti, J.A.2
Seiter, K.3
Niedzwiecki, D.4
Botet, J.5
Martin, D.6
Costa, P.7
Wiseberg, J.8
McCulloch, W.9
-
101
-
-
0023753618
-
Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil
-
Spears, C.P., Gustavsson, B.G., Berne, Frosing, R., Bernstein, L., Hayes, A.A.: Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil. Cancer Res. 45:5894, 1988
-
(1988)
Cancer Res.
, vol.45
, pp. 5894
-
-
Spears, C.P.1
Gustavsson, B.G.2
Berne3
Frosing, R.4
Bernstein, L.5
Hayes, A.A.6
-
102
-
-
0026560328
-
Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorasc gene expression in human tumors using polymerase chain reaction
-
Horikoshi, T., Danenberg, K.D., Stadlbauer, T.H., Volkenandt, M., Shea, L.C., Aigner, K., Gustawson, B., Leichman, L., Frosing, R., Ray, M.: Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorasc gene expression in human tumors using polymerase chain reaction. Cancer Res. 52:108, 1992
-
(1992)
Cancer Res.
, vol.52
, pp. 108
-
-
Horikoshi, T.1
Danenberg, K.D.2
Stadlbauer, T.H.3
Volkenandt, M.4
Shea, L.C.5
Aigner, K.6
Gustawson, B.7
Leichman, L.8
Frosing, R.9
Ray, M.10
-
103
-
-
0028940399
-
Thymidylate gene and protein expression correlate associated with response to 5-fluorouracil in human colorectal and gastric tumors
-
Johnston, P.G., Lenz, H.J., Leichman, C.G., Danenberg, K.D., Allegra, C.J., Danenberg, P.V., Leichman, L.: Thymidylate gene and protein expression correlate associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res. 55:1407, 1995
-
(1995)
Cancer Res.
, vol.55
, pp. 1407
-
-
Johnston, P.G.1
Lenz, H.J.2
Leichman, C.G.3
Danenberg, K.D.4
Allegra, C.J.5
Danenberg, P.V.6
Leichman, L.7
-
104
-
-
0001849087
-
Thymidylate synthase protein expression: Association with response to neoadjuvant chemotherapy and resection for locally advanced gastric and gastroesophageal adenocarcinoma
-
Alexander, H.R., Grem, J.L., Hamilton, J.M., Pass, H.I., Hong, M., Fraker, D.L., Steinberg, M., McAtt, N., Allegra, C.J., Johnston, P.G.: Thymidylate synthase protein expression: association with response to neoadjuvant chemotherapy and resection for locally advanced gastric and gastroesophageal adenocarcinoma. Cancer J. 1:49, 1995
-
(1995)
Cancer J.
, vol.1
, pp. 49
-
-
Alexander, H.R.1
Grem, J.L.2
Hamilton, J.M.3
Pass, H.I.4
Hong, M.5
Fraker, D.L.6
Steinberg, M.7
McAtt, N.8
Allegra, C.J.9
Johnston, P.G.10
-
105
-
-
9044250848
-
Thymidylate synthase MRNa level in adenocarcinoma of the stomach: A predictor for primary tumor response and overall survival
-
Lenz, H.J., Leichman, C.G., Danenberg, K.D., Danenberg, P.V., Groshen, S., Cohen, H., Laine, L., Crookes, P., Silverman, H., Baranda, J., Garcia, Y., Li, J., Leichman, L.: Thymidylate synthase MRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival. J. Clin. Oncol. 14:176, 1995
-
(1995)
J. Clin. Oncol.
, vol.14
, pp. 176
-
-
Lenz, H.J.1
Leichman, C.G.2
Danenberg, K.D.3
Danenberg, P.V.4
Groshen, S.5
Cohen, H.6
Laine, L.7
Crookes, P.8
Silverman, H.9
Baranda, J.10
Garcia, Y.11
Li, J.12
Leichman, L.13
-
106
-
-
0024413739
-
Fluorouracil and high-dose leucovorin in previously treated patients with metastatic breast cancer
-
Swain, S.M., Lippman, M.E., Egan, E.F., Drake, J.C., Steinberg, S.M., Allegra, C.J.: Fluorouracil and high-dose leucovorin in previously treated patients with metastatic breast cancer. J. Clin. Oncol. 7:890, 1989
-
(1989)
J. Clin. Oncol.
, vol.7
, pp. 890
-
-
Swain, S.M.1
Lippman, M.E.2
Egan, E.F.3
Drake, J.C.4
Steinberg, S.M.5
Allegra, C.J.6
-
107
-
-
0027416220
-
Regulation of thymidylate synthase in human colon cells treated with 5-fluorouracil and interferon-gamma
-
Chu, E., Koeller, D.M., Johnston, P.G., Zinn, S., Allegra, C.J.: Regulation of thymidylate synthase in human colon cells treated with 5-fluorouracil and interferon-gamma. Mol. Pharmacol. 43:527, 1993
-
(1993)
Mol. Pharmacol.
, vol.43
, pp. 527
-
-
Chu, E.1
Koeller, D.M.2
Johnston, P.G.3
Zinn, S.4
Allegra, C.J.5
-
108
-
-
0025997350
-
ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: A new agent for clinical study
-
Jackman, A.L., Taylor, G.A., Gibson, W., Kiinbell, R., Brown, M., Calvert, A.H., Judson, I.R., Hughes, L.R.: ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study. Cancer Res. 51:5579, 1991
-
(1991)
Cancer Res.
, vol.51
, pp. 5579
-
-
Jackman, A.L.1
Taylor, G.A.2
Gibson, W.3
Kiinbell, R.4
Brown, M.5
Calvert, A.H.6
Judson, I.R.7
Hughes, L.R.8
-
109
-
-
15644382547
-
New agents in the treatment of colorectal cancer: Tomudex, UFT and doxifluridine
-
abstr
-
Pazdur, R.: New agents in the treatment of colorectal cancer: tomudex, UFT and doxifluridine. Cancer Invest. 12:18, 1995 (abstr)
-
(1995)
Cancer Invest.
, vol.12
, pp. 18
-
-
Pazdur, R.1
-
110
-
-
15644362946
-
ZD1694 A new thymidylate synthase inhibitor: Results in the treatment of colorectal carcinoma
-
abstr
-
Zaleberg, J.: ZD1694 A new thymidylate synthase inhibitor: results in the treatment of colorectal carcinoma. Cancer Invest. 12:43, 1994 (abstr)
-
(1994)
Cancer Invest.
, vol.12
, pp. 43
-
-
Zaleberg, J.1
-
111
-
-
0009687187
-
Tolmudex (ZD1694) a new thymidylate synthase inhibitor with good antitumor activity in advanced colorectal cancer
-
abstr
-
Cunningham, D., Zaleberg, J., Francoise van Cutsem, E., Schornagel, J.H., Adenis, A., Green, M., Starkhammer, H., Hanrahan, A., Ellis, P., Azab, M.: Tolmudex (ZD1694) a new thymidylate synthase inhibitor with good antitumor activity in advanced colorectal cancer. Proc. Am. Soc. Clin. Oncol. 13:199, 1994 (abstr)
-
(1994)
Proc. Am. Soc. Clin. Oncol.
, vol.13
, pp. 199
-
-
Cunningham, D.1
Zaleberg, J.2
Van Francoise Cutsem, E.3
Schornagel, J.H.4
Adenis, A.5
Green, M.6
Starkhammer, H.7
Hanrahan, A.8
Ellis, P.9
Azab, M.10
-
112
-
-
0010695948
-
Final results and survival data of a large randomized trial of tomudex in advanced colorectal cancer (ACC) confirm comparable efficacy to 5-fluorouracil plus leucovorin (5FU + IV)
-
abstr
-
Seitz, J.E., Cunningham, D., Roth, U., Oliver, I.N., vanCutsem, E., Keff, D., Svensson, C., Ferez Manga, G., Harper, P., Zalcberg, J., Lowery, K., Azab, M.: Final results and survival data of a large randomized trial of tomudex in advanced colorectal cancer (ACC) confirm comparable efficacy to 5-fluorouracil plus leucovorin (5FU + IV). Proc. Am. Soc. Clin. Oncol. 15:201, 1966 (abstr)
-
(1966)
Proc. Am. Soc. Clin. Oncol.
, vol.15
, pp. 201
-
-
Seitz, J.E.1
Cunningham, D.2
Roth, U.3
Oliver, I.N.4
VanCutsem, E.5
Keff, D.6
Svensson, C.7
Ferez Manga, G.8
Harper, P.9
Zalcberg, J.10
Lowery, K.11
Azab, M.12
-
113
-
-
0021049802
-
Folate antagonists 20 synthesis and antitumor and antimalarial properties of trimetrexate and related 6-[(phenylaminal)methyl]-2,4-quinazolinediamines
-
Elslager, E.F., Johnson, J.L., Werbel, L.M.: Folate antagonists 20 synthesis and antitumor and antimalarial properties of trimetrexate and related 6-[(phenylaminal)methyl]-2,4-quinazolinediamines. J. Med. Chem. 26:1753, 1983
-
(1983)
J. Med. Chem.
, vol.26
, pp. 1753
-
-
Elslager, E.F.1
Johnson, J.L.2
Werbel, L.M.3
-
114
-
-
0023485116
-
Trimetrexate: Clinical development of a nonclassical antifolate
-
O'Dwyer, P., DeLap, R., Kings, S.A., Grillo-Lopez, A.J.: Trimetrexate: clinical development of a nonclassical antifolate. Natl. Cancer Inst. Monogr. 5:105, 1987
-
(1987)
Natl. Cancer Inst. Monogr.
, vol.5
, pp. 105
-
-
O'Dwyer, P.1
DeLap, R.2
Kings, S.A.3
Grillo-Lopez, A.J.4
-
115
-
-
0021340811
-
1. Update and efficacy of trimetrexate, a nonclassical antifolate in methotrexate resistant leukemia cells in vitro
-
Karnan, B., Cashmore, A., Dreyer, R., Eibi, B., Bertino, J.R.: 1. Update and efficacy of trimetrexate, a nonclassical antifolate in methotrexate resistant leukemia cells in vitro. Biochem. Pharmacol. 33:1697, 1984
-
(1984)
Biochem. Pharmacol.
, vol.33
, pp. 1697
-
-
Karnan, B.1
Cashmore, A.2
Dreyer, R.3
Eibi, B.4
Bertino, J.R.5
-
116
-
-
0018387655
-
Toward improved selectivity in cancer chemotherapy: The Richard and Hinda Rosenthal award lecture
-
Bertino, J.R.: Toward improved selectivity in cancer chemotherapy: the Richard and Hinda Rosenthal award lecture. Cancer Res. 39:293, 1979
-
(1979)
Cancer Res.
, vol.39
, pp. 293
-
-
Bertino, J.R.1
-
117
-
-
0026642174
-
1. Leucovorin enhances cytotoxicity of trimetrexate/fluorouracil, but not methotrexate/fluorouracil in CCRF-CEM cells
-
Romanini, A., Li, W.W., Coloflore, J.R., Bertino, J.R.: 1. Leucovorin enhances cytotoxicity of trimetrexate/fluorouracil, but not methotrexate/fluorouracil in CCRF-CEM cells. J. Natl. Cancer Inst. 84: 1033, 1992
-
(1992)
J. Natl. Cancer Inst.
, vol.84
, pp. 1033
-
-
Romanini, A.1
Li, W.W.2
Coloflore, J.R.3
Bertino, J.R.4
-
118
-
-
0023923192
-
Preclinical studies with trimetrexate: A review of conclusions and unanswered questions
-
Jackson, R.C., Leopold, W.R., Hamelehle, K.L., Fry, D.W.: Preclinical studies with trimetrexate: a review of conclusions and unanswered questions. Semin. Oncol. 15(2):1, 1988
-
(1988)
Semin. Oncol.
, vol.15
, Issue.2
, pp. 1
-
-
Jackson, R.C.1
Leopold, W.R.2
Hamelehle, K.L.3
Fry, D.W.4
-
119
-
-
0023938538
-
Safety and tolerance of trimetrexate: Results of a phase II multicenter study in patients with metastatic cancer refractory to conventional therapy or for which no conventional therapy exists
-
Stewart, J.A.: Safety and tolerance of trimetrexate: results of a phase II multicenter study in patients with metastatic cancer refractory to conventional therapy or for which no conventional therapy exists. Semin. Oncol. 15(2):10, 1988
-
(1988)
Semin. Oncol.
, vol.15
, Issue.2
, pp. 10
-
-
Stewart, J.A.1
-
120
-
-
0023501916
-
Therapeutic synergy of trimetrexate (CI-898) in combination with doxorubicin, vincristine, Cytoxan, thioguanine, cisplatin or 5-fluorouracil against intraperitoneally implanted P388 leukemia
-
Leopold, W.R., Dykes, D.J., Griswold, D.P.: Therapeutic synergy of trimetrexate (CI-898) in combination with doxorubicin, vincristine, Cytoxan, thioguanine, cisplatin or 5-fluorouracil against intraperitoneally implanted P388 leukemia. Natl. Cancer Inst. Monogr. 5:99, 1987
-
(1987)
Natl. Cancer Inst. Monogr.
, vol.5
, pp. 99
-
-
Leopold, W.R.1
Dykes, D.J.2
Griswold, D.P.3
-
121
-
-
0023912294
-
Phase 1 and 2 studies of trimetrexate administered in combination with fluorouracil in patients with metastatic cancer
-
Hudes, G.R., Comis, R.L.: Phase 1 and 2 studies of trimetrexate administered in combination with fluorouracil in patients with metastatic cancer. Semin. Oncol. 15(2):41, 1988
-
(1988)
Semin. Oncol.
, vol.15
, Issue.2
, pp. 41
-
-
Hudes, G.R.1
Comis, R.L.2
-
122
-
-
0021947230
-
Lack of enhanced cytotoxicity of cultured L1210 cells using folinic acid in combination with sequential methotrexate and fluorouracil
-
Danhauser, L.L., Heimer, R., Cadman, E.: Lack of enhanced cytotoxicity of cultured L1210 cells using folinic acid in combination with sequential methotrexate and fluorouracil. Cancer Chemother. Pharmacol. 15:2149, 1985
-
(1985)
Cancer Chemother. Pharmacol.
, vol.15
, pp. 2149
-
-
Danhauser, L.L.1
Heimer, R.2
Cadman, E.3
-
123
-
-
0028323029
-
Trial of sequential trimetrexate, fluorouracil and high-dose leucovorin in previously treated patients with gastrointestinal carcinoma
-
Conti, J.A., Kemeny, N., Seiter, K., Goker, E., Tong, W., Andre, M., Ragusa, K.: Trial of sequential trimetrexate, fluorouracil and high-dose leucovorin in previously treated patients with gastrointestinal carcinoma. J. Clin. Oncol. 12:695, 1994
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 695
-
-
Conti, J.A.1
Kemeny, N.2
Seiter, K.3
Goker, E.4
Tong, W.5
Andre, M.6
Ragusa, K.7
-
124
-
-
15644384252
-
A pilot study of sequential trimetrexate, fluorouracil, and high-dose leucovorin in patients with advanced colorectal cancer
-
Blanke, C.O., Kasimis, B., Capizzi, R.: A pilot study of sequential trimetrexate, fluorouracil, and high-dose leucovorin in patients with advanced colorectal cancer. Cancer Invest. 14:23, 1996
-
(1996)
Cancer Invest.
, vol.14
, pp. 23
-
-
Blanke, C.O.1
Kasimis, B.2
Capizzi, R.3
-
125
-
-
0023552964
-
Antitumor activity of 7-ethyl-10-4-(1-peridono)-1-piperidinol carboxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors
-
Kuniinoto, T., Nitta, K., Tanaka, T., Uehara, N., Baba, H., Takeuchi, M., Yokokura, T., Sawada, S., Miyasaka, T., Mutai, M.: Antitumor activity of 7-ethyl-10-(4-(1-peridono)-1-piperidinol carboxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors. Cancer Res. 47:5944, 1987
-
(1987)
Cancer Res.
, vol.47
, pp. 5944
-
-
Kuniinoto, T.1
Nitta, K.2
Tanaka, T.3
Uehara, N.4
Baba, H.5
Takeuchi, M.6
Yokokura, T.7
Sawada, S.8
Miyasaka, T.9
Mutai, M.10
-
126
-
-
7144248725
-
Plant antitumor agents: The isolation and structure of camptothecin, a novel alkaloid leukemia and tumor inhibitor from Camptotheca ocuminata
-
Wall, M.E., Wani, M.C., Cook, CE.: Plant antitumor agents: the isolation and structure of camptothecin, a novel alkaloid leukemia and tumor inhibitor from Camptotheca ocuminata. J. Am. Clin. Soc. 88:3888, 1966
-
(1966)
J. Am. Clin. Soc.
, vol.88
, pp. 3888
-
-
Wall, M.E.1
Wani, M.C.2
Cook, C.E.3
-
127
-
-
0022340594
-
Camptothecin induces protein-linked breaks via mammalian DNA topoisomerase
-
Hsiang, Y.H., Hartzburg, R., Hecht, S., Liu, L.F.: Camptothecin induces protein-linked breaks via mammalian DNA topoisomerase. Biol. Chem. 60:14873, 1985
-
(1985)
Biol. Chem.
, vol.60
, pp. 14873
-
-
Hsiang, Y.H.1
Hartzburg, R.2
Hecht, S.3
Liu, L.F.4
-
128
-
-
0023924786
-
Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
-
Hsiang, Y-H., Liu, L.P.: Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res. 48: 1722, 1988
-
(1988)
Cancer Res.
, vol.48
, pp. 1722
-
-
Hsiang, Y.-H.1
Liu, L.P.2
-
129
-
-
0025800372
-
DNA topoisomerases: Why so many?
-
Wang, J.C.: DNA topoisomerases: why so many? J. Biol. Chem. 266:6659, 1991
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 6659
-
-
Wang, J.C.1
-
130
-
-
0024316466
-
DNA topoisomerase poisons as antitumor drugs
-
Lin, L.F.: DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem. 58:315, 1989
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 315
-
-
Lin, L.F.1
-
131
-
-
15644382680
-
Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11
-
Kawato, Y., Aonuma, M., Hirota, Y., Kuga, H., Sato, K.: Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res. 57:1487, 1991
-
(1991)
Cancer Res.
, vol.57
, pp. 1487
-
-
Kawato, Y.1
Aonuma, M.2
Hirota, Y.3
Kuga, H.4
Sato, K.5
-
132
-
-
0027194943
-
Phase II study of CPT-11: A new camptothecin derivative in metastatic colorectal cancer
-
Shimada, Y., Yoshino, M., Wakui, A., Nakao, I., Futatsuki, K., Sakata, Y., Kambe, M., Taguchi, T., Ogawa, N.: Phase II study of CPT-11: a new camptothecin derivative in metastatic colorectal cancer. J. Clin. Oncol. 11:909, 1993
-
(1993)
J. Clin. Oncol.
, vol.11
, pp. 909
-
-
Shimada, Y.1
Yoshino, M.2
Wakui, A.3
Nakao, I.4
Futatsuki, K.5
Sakata, Y.6
Kambe, M.7
Taguchi, T.8
Ogawa, N.9
-
133
-
-
0001796566
-
Multicentric phase study of first line CPT-11 (irinotecan) in advanced colorectal cancer (CRC): Preliminary results
-
abstr
-
Rougier, P., Paillot, B., Laplanche, A., Morvan, F., Benhamed, M., Seitz, J.F., Laplaige, P., Jacob, J., Grandjouan, S., Pinon, G.N.: Multicentric phase study of first line CPT-11 (irinotecan) in advanced colorectal cancer (CRC): preliminary results. Proc. Am. Soc. Clin. Oncol. 13:200, 1994 (abstr)
-
(1994)
Proc. Am. Soc. Clin. Oncol.
, vol.13
, pp. 200
-
-
Rougier, P.1
Paillot, B.2
Laplanche, A.3
Morvan, F.4
Benhamed, M.5
Seitz, J.F.6
Laplaige, P.7
Jacob, J.8
Grandjouan, S.9
Pinon, G.N.10
-
134
-
-
0001796567
-
CPT-11 (irinotecan) as second line therapy in advanced colorectal cancer (CRC): Preliminary results of a multicentric phase II study
-
abstr
-
Bugat, R., Suc, E., Rougier, P., Becouam, Y., Naieff, I., Ychou, M., Cutine, S., Extra, J.M., Adenis, A., Ganem, G.: CPT-11 (irinotecan) as second line therapy in advanced colorectal cancer (CRC): preliminary results of a multicentric phase II study. Proc. Am. Soc. Clin. Oncol. 13:200, 1994 (abstr)
-
(1994)
Proc. Am. Soc. Clin. Oncol.
, vol.13
, pp. 200
-
-
Bugat, R.1
Suc, E.2
Rougier, P.3
Becouam, Y.4
Naieff, I.5
Ychou, M.6
Cutine, S.7
Extra, J.M.8
Adenis, A.9
Ganem, G.10
-
135
-
-
0000484548
-
Irinoteca (CPT-11) as second line therapy for patients with 5-FU refractory colorectal cancer
-
abstr
-
Rothenberg, M.L., Echardt, J.R., Burns, H.A., Nelson, J., Kuhn, J.G., Chen, S.F., Hilsenbeck, S.G., Clark, G.M., Fields, S.M., Rodriguez, G.I.: Irinoteca (CPT-11) as second line therapy for patients with 5-FU refractory colorectal cancer. Proc. Am. Soc. Clin. Oncol. 13:198, 1994 (abstr)
-
(1994)
Proc. Am. Soc. Clin. Oncol.
, vol.13
, pp. 198
-
-
Rothenberg, M.L.1
Echardt, J.R.2
Burns, H.A.3
Nelson, J.4
Kuhn, J.G.5
Chen, S.F.6
Hilsenbeck, S.G.7
Clark, G.M.8
Fields, S.M.9
Rodriguez, G.I.10
-
136
-
-
0001271895
-
A phase II trial of CPT-11 in patients with metastatic colorectal carcinoma: A North Central Cancer Treatment Group study
-
abstr
-
Pitot, H.C., Wender, D., O'Connell, M.J., Wieand, H.S., Mailliard, J.A.: A phase II trial of CPT-11 in patients with metastatic colorectal carcinoma: a North Central Cancer Treatment Group study. Proc. Am. Soc. Clin. Oncol. 134:197, 1994 (abstr)
-
(1994)
Proc. Am. Soc. Clin. Oncol.
, vol.134
, pp. 197
-
-
Pitot, H.C.1
Wender, D.2
O'Connell, M.J.3
Wieand, H.S.4
Mailliard, J.A.5
-
137
-
-
0000484557
-
Irinotecan (CPT-11) is an active agent in untreated patients with metastatic colorectal cancer (CRC)
-
abstr
-
Conti, J.A., Kemeny, N.E., Saltz, L.B., Huang, Y., Tong, W.P., Chou, T.C., Sun, M., Pulliam, S., Gonzalez, C.: Irinotecan (CPT-11) is an active agent in untreated patients with metastatic colorectal cancer (CRC). Proc. Am. Soc. Clin. Oncol. 13:195, 1994 (abstr)
-
(1994)
Proc. Am. Soc. Clin. Oncol.
, vol.13
, pp. 195
-
-
Conti, J.A.1
Kemeny, N.E.2
Saltz, L.B.3
Huang, Y.4
Tong, W.P.5
Chou, T.C.6
Sun, M.7
Pulliam, S.8
Gonzalez, C.9
-
138
-
-
0342921336
-
Irinotecan (CPT-11) in combination chemotherapy regimens
-
abstr
-
Saltz, L.B.: Irinotecan (CPT-11) in combination chemotherapy regimens. Cancer Invest. 14:38, 1996 (abstr)
-
(1996)
Cancer Invest.
, vol.14
, pp. 38
-
-
Saltz, L.B.1
-
139
-
-
0016440838
-
Therapy of advanced colorectal cancer with a combination of 5-fluorouracil, methyl-1,3 cis(2 chloroetbyl)-1-nitrosourea, and vincristine
-
Moertel, C.G., Schutt, A.J., Hahn, R.G., Reitemeier, R.J.: Therapy of advanced colorectal cancer with a combination of 5-fluorouracil, methyl-1,3 cis(2 chloroetbyl)-1-nitrosourea, and vincristine. J. Natl. Cancer Inst. 54:69, 1975
-
(1975)
J. Natl. Cancer Inst.
, vol.54
, pp. 69
-
-
Moertel, C.G.1
Schutt, A.J.2
Hahn, R.G.3
Reitemeier, R.J.4
-
140
-
-
0018264312
-
Chemotherapy of gastrointestinal cancer
-
Moertel, C.G.: Chemotherapy of gastrointestinal cancer. N. Engl. J. Med. 299:1049, 1978
-
(1978)
N. Engl. J. Med.
, vol.299
, pp. 1049
-
-
Moertel, C.G.1
-
141
-
-
0017091504
-
Fluorouracil, methyl-CCNU, and vincristine in cancer of the colon
-
Falkson, G., Falkson, H.C.: Fluorouracil, methyl-CCNU, and vincristine in cancer of the colon. Cancer 38:1468, 1976
-
(1976)
Cancer
, vol.38
, pp. 1468
-
-
Falkson, G.1
Falkson, H.C.2
-
142
-
-
15644376140
-
Combination chemotherapy of advanced bowel cancer
-
Engstrom, P., Maclntyre, J., Douglas, H., Carbone, P.: Combination chemotherapy of advanced bowel cancer. Proc. Am. Soc. Clin. Oncol. 19:384, 1978
-
(1978)
Proc. Am. Soc. Clin. Oncol.
, vol.19
, pp. 384
-
-
Engstrom, P.1
Maclntyre, J.2
Douglas, H.3
Carbone, P.4
-
143
-
-
0018413696
-
A randomized study of two different schedules of methyl CCNC, 5-FU and vincristine for metastatic colorectal carcinoma
-
Kemeny, N., Yagoda, A., Braun, D., Jr., Golbey, R.: A randomized study of two different schedules of methyl CCNC, 5-FU and vincristine for metastatic colorectal carcinoma. Cancer 43:78, 1979
-
(1979)
Cancer
, vol.43
, pp. 78
-
-
Kemeny, N.1
Yagoda, A.2
Braun Jr., D.3
Golbey, R.4
-
144
-
-
0018832306
-
Therapy for metastatic colorectal carcinoma with a combination of methylCCNU, 5-fluorouracil, vincristine, and streptozocin (MOF-strep)
-
Kemeny, N., Yagoda, A., Braun, D., Jr., Golbey, R.: Therapy for metastatic colorectal carcinoma with a combination of methylCCNU, 5-fluorouracil, vincristine, and streptozocin (MOF-strep). Cancer 45:876, 1980
-
(1980)
Cancer
, vol.45
, pp. 876
-
-
Kemeny, N.1
Yagoda, A.2
Braun Jr., D.3
Golbey, R.4
-
145
-
-
0020659797
-
Metastatic colon carcinoma: A prospective randomized trial of methyl-CCNU, 5-fluorouracil (5-FU) and vincristine (MOF) versus Mof plus streptozocin (MOP-strep)
-
Kemeny, N., Yagoda, A., Braun, D., Jr.: Metastatic colon carcinoma: a prospective randomized trial of methyl-CCNU, 5-fluorouracil (5-FU) and vincristine (MOF) versus MOF plus streptozocin (MOP-strep). Cancer 51:20, 1983
-
(1983)
Cancer
, vol.51
, pp. 20
-
-
Kemeny, N.1
Yagoda, A.2
Braun Jr., D.3
-
146
-
-
0021613148
-
A phase II study of methyl CCNU, vincristine, 5-fluorouracil, and streptozocin in advanced colorectal cancer
-
Gastrointestinal Tumor Study Group: A phase II study of methyl CCNU, vincristine, 5-fluorouracil, and streptozocin in advanced colorectal cancer. J. Clin. Oncol. 2:770, 1984
-
(1984)
J. Clin. Oncol.
, vol.2
, pp. 770
-
-
-
147
-
-
0018952836
-
Survival and response to chemotherapy for advanced colorectal adenocarcinoma: An Eastern Cooperative Oncology Group report
-
Lavin, P., Mittelman, A., Douglass, H., Engstrom, P., Klaassen, D.: Survival and response to chemotherapy for advanced colorectal adenocarcinoma: an Eastern Cooperative Oncology Group report. Cancer 46:1536, 1986
-
(1986)
Cancer
, vol.46
, pp. 1536
-
-
Lavin, P.1
Mittelman, A.2
Douglass, H.3
Engstrom, P.4
Klaassen, D.5
-
148
-
-
0021637723
-
Chemotherapy of advanced colorectal carcinoma: Fluorouracil alone vs two drug combinations of fluorouracil, hydroxyurea, semunole, dacarbazine, razoxane and mitomycin-C: a phase III trial by the Eastern Cooperative Oncology Group
-
Engstrom, P.F., MacIntyre, J.M., Mittelman, A., Klaasen, DJ.: Chemotherapy of advanced colorectal carcinoma: fluorouracil alone vs two drug combinations of fluorouracil, hydroxyurea, semunole, dacarbazine, razoxane and mitomycin-C: a phase III trial by the Eastern Cooperative Oncology Group. Am. J. Clin. Oncol. 7:313, 1984
-
(1984)
Am. J. Clin. Oncol.
, vol.7
, pp. 313
-
-
Engstrom, P.F.1
MacIntyre, J.M.2
Mittelman, A.3
Klaasen, D.J.4
-
149
-
-
0016201907
-
Fluorouracil, imidazole carboximide dimethyltriazine, vincristine and bis-chloroethylnitrosourea in colon cancer
-
Falkson, G., Van Eden, E.G., Falkson, H.C.: Fluorouracil, imidazole carboximide dimethyltriazine, vincristine and bis-chloroethylnitrosourea in colon cancer. Cancer 33:1207, 1974
-
(1974)
Cancer
, vol.33
, pp. 1207
-
-
Falkson, G.1
Van Eden, E.G.2
Falkson, H.C.3
-
150
-
-
0018152276
-
Phase II trial of 5-fluorouracil, Adriamycin and mitoniycin-C in advanced colorectal cancer
-
Haller, D.G., Woolley, P.V., Macdonald, J.S., Smith, L.F., Schein, P.S.: Phase II trial of 5-fluorouracil, Adriamycin and mitoniycin-C in advanced colorectal cancer. Cancer Treat. Rep. 62:563, 1978
-
(1978)
Cancer Treat. Rep.
, vol.62
, pp. 563
-
-
Haller, D.G.1
Woolley, P.V.2
Macdonald, J.S.3
Smith, L.F.4
Schein, P.S.5
-
151
-
-
0018075598
-
5-FU infusion with mitomycin-C vs 5-FU infusion with methyl CCNU in the treatment of advanced colon cancer
-
Buroker, T., Kim, P.N., Groppe, C., McCracken, J., O'Bryan, R., Panettiere, F., Coltman, C., Bottomley, R., Wilson, H., Bonnet, J., Thigpen, T., Vaitkevicius, V.K., Hoogstraten, B., Heilbrun, L.: 5-FU infusion with mitomycin-C vs 5-FU infusion with methyl CCNU in the treatment of advanced colon cancer. Cancer 42:1228, 1978
-
(1978)
Cancer
, vol.42
, pp. 1228
-
-
Buroker, T.1
Kim, P.N.2
Groppe, C.3
McCracken, J.4
O'Bryan, R.5
Panettiere, F.6
Coltman, C.7
Bottomley, R.8
Wilson, H.9
Bonnet, J.10
Thigpen, T.11
Vaitkevicius, V.K.12
Hoogstraten, B.13
Heilbrun, L.14
-
152
-
-
15644366958
-
A study of the synergistic cytotoxic effects of 5-fluorouracil and cisplatin against colon carcinoma cells using median effect analysis
-
Oritz, J., Woolley, P.V.: A study of the synergistic cytotoxic effects of 5-fluorouracil and cisplatin against colon carcinoma cells using median effect analysis. Proc A.A.C.R. 12:414, 1987
-
(1987)
Proc A.A.C.R.
, vol.12
, pp. 414
-
-
Oritz, J.1
Woolley, P.V.2
-
153
-
-
0027279538
-
A phase II study of continuous infusion 5-flurouracil and leucovorin with weekly cisplatin in metastatic colorectal carcinoma
-
Grem, J.L., McAtee, N., Balis, F., Murphy, R., Venzon, D., Kramer, B., Goldspiel, B., Begley, M., Allegra, C.J.: A phase II study of continuous infusion 5-flurouracil and leucovorin with weekly cisplatin in metastatic colorectal carcinoma. Cancer 72:663, 1993
-
(1993)
Cancer
, vol.72
, pp. 663
-
-
Grem, J.L.1
McAtee, N.2
Balis, F.3
Murphy, R.4
Venzon, D.5
Kramer, B.6
Goldspiel, B.7
Begley, M.8
Allegra, C.J.9
-
154
-
-
15644367675
-
Six week cycles of continuous infusion (CI) 5-FU and weekly low dose cisplatin (DDP) in metastatic colorectal carcinoma
-
abstr
-
Krizan, Z., Dimitrou, D., Suhrland, G., Arnold, D., Cook, D., Schwartz, K., Walker, W.: Six week cycles of continuous infusion (CI) 5-FU and weekly low dose cisplatin (DDP) in metastatic colorectal carcinoma. Proc. Am. Soc. Clin. Oncol. 9:103, 1190 (abstr)
-
(1190)
Proc. Am. Soc. Clin. Oncol.
, vol.9
, pp. 103
-
-
Krizan, Z.1
Dimitrou, D.2
Suhrland, G.3
Arnold, D.4
Cook, D.5
Schwartz, K.6
Walker, W.7
-
155
-
-
0023896783
-
A prospective randomized trial of fluorouracil versus fluorouracil plus cisplatin in the treatment of metastatic colorectal cancer: A Hoosier Oncology Group trial
-
Loehrer, P.J., Turner, S., Kubilis, P., Hui, S., Correa, J., Ansari, R., Stephens, D., Woodburn, R., Meyer, S.: A prospective randomized trial of fluorouracil versus fluorouracil plus cisplatin in the treatment of metastatic colorectal cancer: a Hoosier Oncology Group trial. J. Clin. Oncol. 6:642, 1988
-
(1988)
J. Clin. Oncol.
, vol.6
, pp. 642
-
-
Loehrer, P.J.1
Turner, S.2
Kubilis, P.3
Hui, S.4
Correa, J.5
Ansari, R.6
Stephens, D.7
Woodburn, R.8
Meyer, S.9
-
156
-
-
0025164989
-
Randomized study of continuous infusion fluorouracil vs fluorouracil plus cisplatin in patients with metastatic colorectal cancer
-
Kemeny, N., Israel, K., Niedzwiecki, D., Chapman, D., Botet, J., Minsky, B., Vinciguerra, V., Rosenbluth, R., Bosselli, B., Cochrran, C., Sheehan, K.: Randomized study of continuous infusion fluorouracil vs fluorouracil plus cisplatin in patients with metastatic colorectal cancer. J. Clin. Oncol. 8:313, 1990
-
(1990)
J. Clin. Oncol.
, vol.8
, pp. 313
-
-
Kemeny, N.1
Israel, K.2
Niedzwiecki, D.3
Chapman, D.4
Botet, J.5
Minsky, B.6
Vinciguerra, V.7
Rosenbluth, R.8
Bosselli, B.9
Cochrran, C.10
Sheehan, K.11
-
157
-
-
0000372911
-
Lack of clinical synergism between cisplatin (CDDP) and 5-fluorouracil (5-FU) in advanced colorectal cancer (CRC): Results of a randomized study
-
abstr
-
Diaz-Rubio, E., Milla, A., Jimeno, J., Belon, J., Aranda, E., Diaz Faes, J., Crus Hernandes, J., Ayuso, M.L., Alonso, A., Anton, A., Martin, M., Gonzalez, Larriba, J.L., Sanchiz, F., Navarete, A., Masso, O.: Lack of clinical synergism between cisplatin (CDDP) and 5-fluorouracil (5-FU) in advanced colorectal cancer (CRC): results of a randomized study. Proc. Am. Soc. Clin. Oncol. 7:110, 1988 (abstr)
-
(1988)
Proc. Am. Soc. Clin. Oncol.
, vol.7
, pp. 110
-
-
Diaz-Rubio, E.1
Milla, A.2
Jimeno, J.3
Belon, J.4
Aranda, E.5
Diaz Faes, J.6
Crus Hernandes, J.7
Ayuso, M.L.8
Alonso, A.9
Anton, A.10
Martin, M.11
Gonzalez12
Larriba, J.L.13
Sanchiz, F.14
Navarete, A.15
Masso, O.16
-
158
-
-
0026098769
-
A prospective randomized comparison of protracted infusional 5-fluorouracil with or without weekly bolus cisplatin in metastatic colotectal carcinomas: A Mid-Atlantic Oncology Program study
-
Lokich, J.J., Ahlgren, J., Cantrel, J., Heim, W.J., Wampler, G.L., Gullo, J.J., Fryer, J.G., Alt, D.E.: A prospective randomized comparison of protracted infusional 5-fluorouracil with or without weekly bolus cisplatin in metastatic colotectal carcinomas: a Mid-Atlantic Oncology Program study. Cancer 67:14, 1991
-
(1991)
Cancer
, vol.67
, pp. 14
-
-
Lokich, J.J.1
Ahlgren, J.2
Cantrel, J.3
Heim, W.J.4
Wampler, G.L.5
Gullo, J.J.6
Fryer, J.G.7
Alt, D.E.8
-
159
-
-
0000488490
-
Phase II multicentric trial of oxaliplatin (L-OHP) as first line chemotherapy in metastatic colorectal carcinoma (in CRC)
-
abstr
-
Diaz-Rubio, E., Zaniboni, A., Gastiaburn, J., Labianca, R., CortezFunes, H., DeBraud, F., Boni, C., Vignoud, J.: Phase II multicentric trial of oxaliplatin (L-OHP) as first line chemotherapy in metastatic colorectal carcinoma (in CRC). Proc. Am. Soc. Clin. Oncol. 15:207, 1996 (abstr)
-
(1996)
Proc. Am. Soc. Clin. Oncol.
, vol.15
, pp. 207
-
-
Diaz-Rubio, E.1
Zaniboni, A.2
Gastiaburn, J.3
Labianca, R.4
Cortezfunes, H.5
DeBraud, F.6
Boni, C.7
Vignoud, J.8
-
160
-
-
8544272067
-
Chronomodulated vs flat infusion of 5-fluorouracil (5-FU), folinic acid (FA), and oxaliplatin (L-OHP) against metastatic colorectal cancer (MCC) in 2 consecutive European randomized multicenter trials (T)
-
abstr
-
Levi, F., Zidani, R., Vannetzel, J.M., Fagguiolo, R., Garufi, C., Chellet, P., Focan, C., Perpoint, B., Iacobelli, S., Le-Roi, A.: Chronomodulated vs flat infusion of 5-fluorouracil (5-FU), folinic acid (FA), and oxaliplatin (L-OHP) against metastatic colorectal cancer (MCC) in 2 consecutive European randomized multicenter trials (T). Proc. Am. Soc. Clin. Oncol. 14:204, 1995 (abstr)
-
(1995)
Proc. Am. Soc. Clin. Oncol.
, vol.14
, pp. 204
-
-
Levi, F.1
Zidani, R.2
Vannetzel, J.M.3
Fagguiolo, R.4
Garufi, C.5
Chellet, P.6
Focan, C.7
Perpoint, B.8
Iacobelli, S.9
Le-Roi, A.10
-
161
-
-
0346774490
-
Continuous infusion 5-fluorouracil given with calcium leucovorin, dipyridamole, and mitomycin-C in patients with advanced colorectal carcinoma: A phase II trial
-
Isacoff, W.H., Eilber, F.R., Kuchenbecker, S.L., Jacobs, A.D., Taylor, O.: Continuous infusion 5-fluorouracil given with calcium leucovorin, dipyridamole, and mitomycin-C in patients with advanced colorectal carcinoma: a phase II trial. J. Infus. Chemother. 4:107, 1994
-
(1994)
J. Infus. Chemother.
, vol.4
, pp. 107
-
-
Isacoff, W.H.1
Eilber, F.R.2
Kuchenbecker, S.L.3
Jacobs, A.D.4
Taylor, O.5
|