Molecular modeling of substrate binding in wild-type and mutant Corynebacteria 2,5-Diketo-D-gluconate reductases

Proteins: Structure, Function and Genetics

Volumn 39, Issue 1, 2000, Pages 68-75

  Khurana, Sumit ^a   Sanli, Gulsah ^a   Powers, David B ^b   Anderson, Stephen ^c   Blaber, Michael ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

2,5 diketo D gluconate; Aldo keto reductase; L ascorbate; Molecular dynamics; Molecular modeling; Substrate recognition; Vitamin C

Indexed keywords

2,5 DIOXOGLUCONATE REDUCTASE; ASCORBIC ACID; BACTERIAL ENZYME; GLUCOSE; MUTANT PROTEIN; OXIDOREDUCTASE; PROTON; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CORYNEBACTERIUM; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION;

AMINO ACID SUBSTITUTION; BINDING SITES; CORYNEBACTERIUM; ISOENZYMES; MODELS, MOLECULAR; POINT MUTATION; PROTEIN CONFORMATION; SUGAR ALCOHOL DEHYDROGENASES; THERMODYNAMICS; VARIATION (GENETICS);

BACTERIA (MICROORGANISMS); CORYNEBACTERIA; CORYNEBACTERIUM;

EID: 0033995602     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(20000401)39:1<68::AID-PROT7>3.0.CO;2-Y     Document Type: Article

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