Lactate/glucose dynamics after rat fluid percussion brain injury

Journal of Neurotrauma

Volumn 17, Issue 2, 2000, Pages 135-142

  Chen, Tao ^a   Qian, Yong Zhen ^a   Di, Xiao ^a   Rice, Ann ^a   Zhu, Jie Pei ^a   Bullock, Ross ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glucose; Lactate; Microdialysate; Traumatic brain injury

Indexed keywords

GLUCOSE; LACTIC ACID;

ANIMAL MODEL; ARTERIAL GAS; ARTICLE; BRAIN INJURY; BRAIN METABOLISM; CONTROLLED STUDY; DIALYSATE; HYPOXIA; MALE; MEAN ARTERIAL PRESSURE; MICRODIALYSIS; NONHUMAN; RAT; RECTUM TEMPERATURE;

EID: 0033994101     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2000.17.135     Document Type: Article

References (44)

1. ANDERSEN, B.J., and MARMAROU, A. (1992). Functional compartmentalization of energy production in neural tissue. Brain Res. 585, 190-195.
2. ANDERSEN, B.J., and MARMAROU, A. (1992). Post-traumatic selective stimulation of glycolysis. Brain Res. 585, 184-189.
3. ANDERSEN, B.J., UNTERBERG, A.W., CLARKE, G.D., and MARMAROU, A. (1988). Effect of posttraumatic hypoventilation on cerebral energy metabolism. J. Neurosurg. 68, 601-607.
4. BROWN, J.I., BAKER, A.J., KONASIEWICZ, S.J., and MOULTON, R.J. (1998). Clinical significance of CSF glutamate concentrations following severe traumatic brain injury in humans. J. Neurotrauma 15, 253-263.
5. BULLOCK, R., ZAUNER, A., WOODWARD, J.J., et al. (1998). Factors affecting excitatory amino acid release following severe human head injury. J. Neurosurg. 89, 507-518.
6. BULLOCK, R., ZAUNER, A., MYSEROS, J.S., MARMAROU, A., WOODWARD, J.J., and YOUNG, H.F. (1995). Evidence for prolonged release of excitatory amino acids in severe human head trauma. Relationship to clinical events. Ann. N.Y. Acad. Sci. 765, 290-298.
7. CROCKARD, H.A., and TAYLOR, A.R. (1972). Serial CSF lactate-pyruvate values as a guide to prognosis in head injury coma. Eur. Neurol. 8, 151-157.
8. + ion channel blockade fails to ameliorate behavioral deficits after traumatic brain injury in the rat. J. Neurotrauma 11, 497-504.
9. DIXON, C.E., LYETH, B.G., POVLISHOCK, J.T., et al. (1987). A fluid percussion model of experimental brain injury in the rat. J. Neurosurg. 67, 110-119.
10. DREWES, L.R., GILBOE, D.D., and BETZ, A.L. (1973). Metabolic alterations in brain during anoxic-anoxia and subsequent recovery. Arch. Neurol. 29, 385-390.
11. ENEVOLDSEN, E.M., and JENSEN, F.T. (1977). Cerebrospinal fluid lactate and pH in patients with acute severe head injury. Clin. Neurol. Neurosurg. 80, 213-225.
12. FERNANDES, J., BERGER, R., and SMIT, G.P. (1982). Lactate as energy source for brain in glucose-6-phosphatase deficient child [Letter]. Lancet 1, 113.
13. GLOBUS, M.Y., ALONSO, O., DIETRICH, W.D., BUSTO, R., and GINSBERG, M.D. (1995). Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia. J. Neurochem. 65, 1704-1711.
14. GOODMAN, J.C., VALADKA, A.B., GOPINATH, S.P., CORMIO, M., and ROBERTSON, C.S. (1996). Lactate and excitatory amino acids measured by microdialysis are decreased by pentobarbital coma in head-injured patients. J. Neurotrauma 13, 549-556.
15. HAMBERGER, A., RUNNERSTAM, M., NYSTROM, B., STARMARK, J.E., and VON ESSEN, C. (1995). The neuronal environment after subarachnoid hemorrhage - correlation of amino acid and nucleoside levels with post-operative recovery. Neurol. Res. 17, 97-105.
16. HOSSMANN, K.A., and KLEIHUES, P. (1973). Reversibility of ischemic brain damage. Arch. Neurol. 29, 375-384.
17. INAO, S., MARMAROU, A., CLARKE, G.D., ANDERSEN, B.J., FATOUROS, P.P., and YOUNG, H.F. (1988). Production and clearance of lactate from brain tissue, cerebrospinal fluid, and serum following experimental brain injury. J. Neurosurg. 69, 736-744.
18. IZUMI, Y., BENZ, A.M., ZORUMSKI, C.F., and OLNEY, J.W. (1994). Effects of lactate and pyruvate on glucose deprivation in rat hippocampal slices. Neuroreport 5, 617-620.
19. KATAYAMA, Y., BECKER, D.P., TAMURA, T., and HOVDA, D.A. (1990). Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J. Neurosurg. 73, 889-900.
20. KAWAMATA, T., KATAYAMA, Y., HOVDA, D.A., YOSHINO, A., and BECKER, D.P. (1995). Lactate accumulation following concussive brain injury: the role of ionic fluxes induced by excitatory amino acids. Brain Res. 674, 196-204.
21. KING, L.R., MCLAURIN, R.L., and KNOWLES, H.C., JR. (1974). Acid-base balance and arterial and CSF lactate levels following human head injury. J. Neurosurg. 440, 617-625.
22. KNUDSEN, G.M., PAULSON, O.B., and HERTZ, M.M. (1991). Kinetic analysis of the human blood-brain barrier transport of lactate and its influence by hypercapnia. J. Cereb. Blood Flow Metab. 11, 581-586.
23. KOIZUMI, H., FUJISAWA, H., ITO, H., MAEKAWA, T., DI, X., and BULLOCK, R. (1997). Effects of mild hypothermia on cerebral blood flow-independent changes in cortical extracellular levels of amino acids following contusion trauma in the rat. Brain Res. 747, 304-312.
24. LJUNGGREN, B., NORBERG, K., and SIESJO, B.K. (1974). Influence of tissue acidosis upon restitution of brain energy metabolism following total ischemia. Brain Res. 77, 173-186.
25. 31P nuclear magnetic resonance. J. Neurochem. 49, 1530-1540.
26. METZEL, E., and ZIMMERMANN, W.E. (1971). Changes of oxygen pressure, acid-base balance, metabolites and electrolytes in cerebrospinal fluid and blood after cerebral injury. Acta Neurochir. (Wien) 25, 177-188.
27. NILSSON, P., HILLERED, L., PONTEN, U., and UNGERSTEDT, U. (1990). Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats. J. Cereb. Blood Flow Metab. 10, 631-637.
28. 2+ levels following cortical compression contusion trauma in rats. J. Cereb. Blood Flow Metab. 13, 183-192.
29. OLDENDORF, W.H. (1971). Blood-brain barrier permeability to lactate. Eur. Neurol. 6, 49-55.
30. PELLERIN, L., and MAGISTRETTI, P.J. (1994). Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc. Natl. Acad. Sci. U.S.A. 91, 10625-10629.
31. REHNCRONA, S., ROSEN, I., and SIESJO, B.K. (1981). Brain lactic acidosis and ischemic cell damage. 1. Biochemistry and neurophysiology. J. Cereb. Blood Flow Metab. 1, 297-311.
32. SCHURR, A., PAYNE, R.S., MILLER, J.J., and RIGOR, B.M. (1997). Brain lactate, not glucose, fuels the recovery of synaptic function from hypoxia upon reoxygenation: an in vitro study. Brain Res. 744, 105-111.
33. SCHURR, A., WEST, C.A., REID, K.H., TSENG, M.T., REISS, S.J., and RIGOR, B.M. (1987). Increased glucose improves recovery of neuronal function after cerebral. Brain Res. 421, 135-139.
34. SCHURR, A., WEST, C.A., and RIGOR, B.M. (1988). Lactate-supported synaptic function in the rat hippocampal slice preparation. Science 240, 1326-1328.
35. SEITZ, H.D. (1976). Gas levels and biochemical changes in cerebrospinal fluid after experimental brain injury: its effect on cerebral circulation and cerebral metabolism as well as its management. Z. Exp. Chir. 9, 341-354.
36. SIEGEL, J.H., RIVKIND, A.I., DALAL, S., and GOODARZI, S. (1990). Early physiologic predictors of injury severity and death in blunt multiple trauma. Arch. Surg. 125, 498-508.
37. SIESJO, B.K. (1981). Cell damage in the brain: a speculative synthesis. J. Cereb. Blood Flow Metab. 1, 155-185.
38. SIESJO, B.K., and LJUNGGREN, B. (1973). Cerebral energy reserves after prolonged hypoxia and ischemia. Arch. Neurol. 29, 400-407.
39. STITTSWORTH, J.D., JR., and LANTHORN, T.H. (1993). Lactate mimics only some effects of D-glucose on epileptic depolarization and long-term synaptic failure. Brain Res. 630, 21-27.
40. VALADKA, A.B., GOODMAN, J.C., GOPINATH, S.P., UZURA, M., and ROBERTSON, C.S. (1998). Comparison of brain tissue oxygen tension to microdialysis-based measures of cerebral ischemia in fatally head-injured humans. J. Neurotrauma 15, 509-519.
41. VESPA, P., PRINS, M., RONNE-ENGSTROM, E., et al. (1998). Increase in extracellular glutamate caused by reduced cerebral perfusion pressure and seizures after human traumatic brain injury: a microdialysis study. J. Neurosurg. 89, 971-982.
42. TUAN, X.Q., and WADE, C.E. (1993). Lactated Ringer's solution alleviates brain trauma-precipitated lactic acidosis in hemorrhagic shock. J. Neurotrauma 10, 307-313.
43. ZAUNER, A., DOPPENBERG, E.M., WOODWARD, J.J., CHOI, S.C., YOUNG, H.F., and BULLOCK, R. (1997). Continuous monitoring of cerebral substrate delivery and clearance: initial experience in 24 patients with severe acute brain injuries. Neurosurgery 41, 1082-1093.
44. ZUPPING, R. (1970). Cerebral acid-base and gas metabolism in brain injury. J. Neurosurg. 33, 498-505.