-
1
-
-
0023924786
-
Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
-
Hsiang Y-H, Liu LF: Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 48:1722-1726, 1988
-
(1988)
Cancer Res
, vol.48
, pp. 1722-1726
-
-
Hsiang, Y.-H.1
Liu, L.F.2
-
2
-
-
0024229066
-
Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin
-
Eng W-K, Faucette L, Johnson RK, et al: Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin. Mol Pharmacol 34:755-760, 1988
-
(1988)
Mol Pharmacol
, vol.34
, pp. 755-760
-
-
Eng, W.-K.1
Faucette, L.2
Johnson, R.K.3
-
3
-
-
0027972726
-
Topoisomerase I inhibitors: Topotecan and irinotecan
-
Creemers GJ, Lund B, Verweij J: Topoisomerase I inhibitors: Topotecan and irinotecan. Cancer Treat Rev 20:73-96, 1994
-
(1994)
Cancer Treat Rev
, vol.20
, pp. 73-96
-
-
Creemers, G.J.1
Lund, B.2
Verweij, J.3
-
4
-
-
0029047211
-
Inhibition of cis-diamminedichloroplatinum (II)-induced DNA interstrand cross-link removal by 7-ethyl-10-hydroxy-camptothecin in HST-1 human squamous-carcinoma cells
-
Masumoto N, Nakano S, Esaki T, et al: Inhibition of cis-diamminedichloroplatinum (II)-induced DNA interstrand cross-link removal by 7-ethyl-10-hydroxy-camptothecin in HST-1 human squamous-carcinoma cells. Int J Cancer 62:70-75, 1995
-
(1995)
Int J Cancer
, vol.62
, pp. 70-75
-
-
Masumoto, N.1
Nakano, S.2
Esaki, T.3
-
5
-
-
0024532122
-
Inhibition of potentially lethal DNA damage repair in human tumor cells by beta-Lapachone, an activator of topoisomerase I
-
Boothman DA, Trask DK, Pardee AB: Inhibition of potentially lethal DNA damage repair in human tumor cells by beta-Lapachone, an activator of topoisomerase I. Cancer Res 49:605-612, 1989
-
(1989)
Cancer Res
, vol.49
, pp. 605-612
-
-
Boothman, D.A.1
Trask, D.K.2
Pardee, A.B.3
-
6
-
-
0343928169
-
Regulation of topoisomerase I activity following DNA damage: Evidence for a topoisomerase I complex
-
abstr 1214
-
Rumbos H, Grosovsky A: Regulation of topoisomerase I activity following DNA damage: Evidence for a topoisomerase I complex. Proc Am Assoc Cancer Res 38:181, 1997 (abstr 1214)
-
(1997)
Proc Am Assoc Cancer Res
, vol.38
, pp. 181
-
-
Rumbos, H.1
Grosovsky, A.2
-
7
-
-
0030068657
-
Synergism between cisplatin and topoisomerase I inhibitors, NB-506 and SN-38, in human small cell lung cancer cells
-
Fukuda M, Nishio K, Kanzawa F, et al: Synergism between cisplatin and topoisomerase I inhibitors, NB-506 and SN-38, in human small cell lung cancer cells. Cancer Res 56:789-793, 1996
-
(1996)
Cancer Res
, vol.56
, pp. 789-793
-
-
Fukuda, M.1
Nishio, K.2
Kanzawa, F.3
-
8
-
-
0003164399
-
Down-regulation of topoisomerase I induced by cisplatin
-
abstr 99
-
Aoe K, Kiura K, Ueoka H, et al: Down-regulation of topoisomerase I induced by cisplatin. Proc Am Assoc Cancer Res 38:15, 1997 (abstr 99)
-
(1997)
Proc Am Assoc Cancer Res
, vol.38
, pp. 15
-
-
Aoe, K.1
Kiura, K.2
Ueoka, H.3
-
9
-
-
0003243748
-
Remarkable synergistic interaction between camptothecin analogs and cisplatin against human esophageal cancer cell lines
-
abstr 101
-
Takiyama I, Terashima M, Ikeda K, et al: Remarkable synergistic interaction between camptothecin analogs and cisplatin against human esophageal cancer cell lines. Proc Am Assoc Cancer Res 38:15, 1997 (abstr 101)
-
(1997)
Proc Am Assoc Cancer Res
, vol.38
, pp. 15
-
-
Takiyama, I.1
Terashima, M.2
Ikeda, K.3
-
10
-
-
0031965435
-
Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a panel of eight solid-tumor cell lines in vitro
-
Ma J, Maliepaard M, Nooter K, et al: Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a panel of eight solid-tumor cell lines in vitro. Cancer Chemother Pharmacol 41:307-316, 1998
-
(1998)
Cancer Chemother Pharmacol
, vol.41
, pp. 307-316
-
-
Ma, J.1
Maliepaard, M.2
Nooter, K.3
-
11
-
-
84871474508
-
Schedule-dependent cytotoxicity of topotecan or SN-38 and platinum (H) and (IV) compounds in vitro
-
abstr 92
-
Maliepaard M, van Klink Y, Root BJG, et al: Schedule-dependent cytotoxicity of topotecan or SN-38 and platinum (H) and (IV) compounds in vitro. Proc 8th Conf DNA Topoisomerase 1997 (abstr 92)
-
(1997)
Proc 8th Conf DNA Topoisomerase
-
-
Maliepaard, M.1
Van Klink, Y.2
Root, B.J.G.3
-
12
-
-
0026587170
-
Effects of CPT-11 in combination with other anti-cancer agents in culture
-
Kano Y, Suzuki K, Akutsu M, et al: Effects of CPT-11 in combination with other anti-cancer agents in culture. Int J Cancer 50:604-610, 1992
-
(1992)
Int J Cancer
, vol.50
, pp. 604-610
-
-
Kano, Y.1
Suzuki, K.2
Akutsu, M.3
-
13
-
-
0343492426
-
CPT-11/cisplatin: An effective preclinical combination in the therapy of advanced human bladder cancer (TCC)
-
abstr 1605
-
Keane T, McGuire W, Petros J, et al: CPT-11/cisplatin: An effective preclinical combination in the therapy of advanced human bladder cancer (TCC). Proc Am Soc Clin Oncol 14:491, 1995 (abstr 1605)
-
(1995)
Proc Am Soc Clin Oncol
, vol.14
, pp. 491
-
-
Keane, T.1
McGuire, W.2
Petros, J.3
-
14
-
-
0025118047
-
Effect of topoisomerase modulators on cisplatin cytotoxicity in human ovarian carcinoma cells
-
Katz EJ, Vick JS, Kling KM. et al: Effect of topoisomerase modulators on cisplatin cytotoxicity in human ovarian carcinoma cells. Eur J Cancer 26:724-727, 1990
-
(1990)
Eur J Cancer
, vol.26
, pp. 724-727
-
-
Katz, E.J.1
Vick, J.S.2
Kling, K.M.3
-
15
-
-
0027082880
-
CPT-11 in combination with cisplatin for advanced non-small-cell lung cancer
-
Masuda N, Fukuoka M, Takada M, et al: CPT-11 in combination with cisplatin for advanced non-small-cell lung cancer. J Clin Oncol 10:1775-1780, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 1775-1780
-
-
Masuda, N.1
Fukuoka, M.2
Takada, M.3
-
16
-
-
0027372606
-
Phase I and pharmacologic study of irinotecan in combination with cisplatin for advanced lung cancer
-
Masuda N, Fukuoka M, Kudoh S, et al: Phase I and pharmacologic study of irinotecan in combination with cisplatin for advanced lung cancer. Br J Cancer 68:777-782, 1993
-
(1993)
Br J Cancer
, vol.68
, pp. 777-782
-
-
Masuda, N.1
Fukuoka, M.2
Kudoh, S.3
-
17
-
-
0011811413
-
Phase I study of irinotecan (CPT-11) in combination with cisplatin (CDDP) on cervical carcinoma
-
abstr 856
-
Sugiyama T, Takeuchi S, Noda K, et al: Phase I study of irinotecan (CPT-11) in combination with cisplatin (CDDP) on cervical carcinoma. Proc Am Soc Clin Oncol 13:268, 1994 (abstr 856)
-
(1994)
Proc Am Soc Clin Oncol
, vol.13
, pp. 268
-
-
Sugiyama, T.1
Takeuchi, S.2
Noda, K.3
-
18
-
-
7144254457
-
Irinotecan (CPT-11) in combination with weekly administration of cisplatin (CDDP) for non-small cell lung cancer
-
Kobayashi K, Shinbara A, Kamimura M, et al: Irinotecan (CPT-11) in combination with weekly administration of cisplatin (CDDP) for non-small cell lung cancer. Cancer Chemother Pharmacol 42:53-58, 1998
-
(1998)
Cancer Chemother Pharmacol
, vol.42
, pp. 53-58
-
-
Kobayashi, K.1
Shinbara, A.2
Kamimura, M.3
-
19
-
-
0031055829
-
Phase I-II study of irinotecan hydrochloride combined with cisplatin in patients with advanced gastric cancer
-
Shirao K, Shimada Y, Kondo H, et al: Phase I-II study of irinotecan hydrochloride combined with cisplatin in patients with advanced gastric cancer. J Clin Oncol 15:921-927, 1997
-
(1997)
J Clin Oncol
, vol.15
, pp. 921-927
-
-
Shirao, K.1
Shimada, Y.2
Kondo, H.3
-
20
-
-
0033063624
-
Fractionated administration of irinotecan and cisplatin for treatment of lung cancer: A phase I study
-
Ueoka H, Tabata M, Kiuraa K, et al: Fractionated administration of irinotecan and cisplatin for treatment of lung cancer: A phase I study. Br J Cancer 79:984-990, 1998
-
(1998)
Br J Cancer
, vol.79
, pp. 984-990
-
-
Ueoka, H.1
Tabata, M.2
Kiuraa, K.3
-
21
-
-
0031015720
-
A phase I study of irinotecan and infusional cisplatin for advanced non-small-cell lung cancer
-
Mori K, Ohnishi T, Yokoyama K, et al: A phase I study of irinotecan and infusional cisplatin for advanced non-small-cell lung cancer. Cancer Chemother Pharmacol 39:327-332, 1997
-
(1997)
Cancer Chemother Pharmacol
, vol.39
, pp. 327-332
-
-
Mori, K.1
Ohnishi, T.2
Yokoyama, K.3
-
22
-
-
0032407409
-
Phase I clinical and pharmacologie study of weekly cisplatin combined with weekly irinotecan in patients with advanced solid tumors
-
Saltz LB, Spriggs D, Schaaf LJ, et al: Phase I clinical and pharmacologie study of weekly cisplatin combined with weekly irinotecan in patients with advanced solid tumors. J Clin Oncol 16:3858-3865, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 3858-3865
-
-
Saltz, L.B.1
Spriggs, D.2
Schaaf, L.J.3
-
23
-
-
0028175150
-
Phase I study of irinotecan and cisplatin with granulocyte colony-stimulating factor support for advanced non-small-cell lung cancer
-
Masuda N, Fukuoka M, Kudoh S, et al: Phase I study of irinotecan and cisplatin with granulocyte colony-stimulating factor support for advanced non-small-cell lung cancer. J Clin Oncol 12:90-96, 1994
-
(1994)
J Clin Oncol
, vol.12
, pp. 90-96
-
-
Masuda, N.1
Fukuoka, M.2
Kudoh, S.3
-
24
-
-
0031106353
-
A phase I study of irinotecan and infusional cisplatin with recombinant human granulocyte colony-stimulating factor support in the treatment of advanced non-small cell lung cancer
-
Mori K, Hirose T, Machida S, et al: A phase I study of irinotecan and infusional cisplatin with recombinant human granulocyte colony-stimulating factor support in the treatment of advanced non-small cell lung cancer. Eur J Cancer 33:503-505, 1997
-
(1997)
Eur J Cancer
, vol.33
, pp. 503-505
-
-
Mori, K.1
Hirose, T.2
Machida, S.3
-
25
-
-
4244113317
-
Phase II study irinotecan and infusional cisplatin with recombinant human granulocyte colony-stimulating factor support in the treatment of advanced non-small cell lung cancer
-
abstr 1714
-
Mori K, Hirose T, Tominaga K: Phase II study irinotecan and infusional cisplatin with recombinant human granulocyte colony-stimulating factor support in the treatment of advanced non-small cell lung cancer. Proc Am Soc Clin Oncol 16:476a, 1997 (abstr 1714)
-
(1997)
Proc Am Soc Clin Oncol
, vol.16
-
-
Mori, K.1
Hirose, T.2
Tominaga, K.3
-
26
-
-
0345505291
-
Phase II trial of irinotecan (CPT-11) plus cispiatin (CDDP) in advanced NSCLC
-
abstr 1674
-
DeVore R, Crawford J, Dimery I., et al: Phase II trial of irinotecan (CPT-11) plus cispiatin (CDDP) in advanced NSCLC. Proc Am Soc Clin Oncol 16:466a, 1997 (abstr 1674)
-
(1997)
Proc Am Soc Clin Oncol
, vol.16
-
-
DeVore, R.1
Crawford, J.2
Dimery, I.3
-
27
-
-
0031887545
-
Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer
-
Kudoh S, Fujiwara Y, Takada Y, et al: Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer. J Clin Oncol 16:1068-1074, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 1068-1074
-
-
Kudoh, S.1
Fujiwara, Y.2
Takada, Y.3
-
28
-
-
0031055829
-
Phase I-II study of irinotecan hydrochloride combined with cisplatin in patients with advanced gastric cancer
-
Shirao K, Kondo H, Saito D, et al: Phase I-II study of irinotecan hydrochloride combined with cisplatin in patients with advanced gastric cancer. J Clin Oncol 15:921-927, 1997
-
(1997)
J Clin Oncol
, vol.15
, pp. 921-927
-
-
Shirao, K.1
Kondo, H.2
Saito, D.3
-
29
-
-
0032547039
-
Irinotecan (CPT-11) combined with cisplatin in patients with refractory or recurrent ovarian cancer
-
Sugiyama T, Yakushiji M, Nishida T, et al: Irinotecan (CPT-11) combined with cisplatin in patients with refractory or recurrent ovarian cancer. Cancer Lett 128:211-218, 1998
-
(1998)
Cancer Lett
, vol.128
, pp. 211-218
-
-
Sugiyama, T.1
Yakushiji, M.2
Nishida, T.3
-
30
-
-
0007426114
-
Multicentric phase II trial of irinotecan (CPT-11) and cisplatin as first-line chemotherapy in recurrent or advanced cervical cancer: Japan CPT-11 study group trial
-
abstr 1360
-
Sugiyama T, Noda K, Yakushiji M: Multicentric phase II trial of irinotecan (CPT-11) and cisplatin as first-line chemotherapy in recurrent or advanced cervical cancer: Japan CPT-11 study group trial. Proc Am Soc Clin Oncol 17:352a, 1998 (abstr 1360)
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Sugiyama, T.1
Noda, K.2
Yakushiji, M.3
-
31
-
-
0030815672
-
Determination of irinotecan (CPT-11) and its active metabolite SN-38 in human plasma by reversed-phase high-performance liquid chromatography with fluorescence detection
-
De Bruijn P, Verweij J, Loos WJ, et al: Determination of irinotecan (CPT-11) and its active metabolite SN-38 in human plasma by reversed-phase high-performance liquid chromatography with fluorescence detection. J Chromatogr 698:277-285, 1997
-
(1997)
J Chromatogr
, vol.698
, pp. 277-285
-
-
De Bruijn, P.1
Verweij, J.2
Loos, W.J.3
-
32
-
-
0032493799
-
Liquid Chromatographic determination of irinotecan and three major metabolites in human plasma, urine and feces
-
Sparreboom A, De Bruijn P, De Jonge MJA, et al: Liquid Chromatographic determination of irinotecan and three major metabolites in human plasma, urine and feces. J Chromatogr B 712:225-235, 1998
-
(1998)
J Chromatogr B
, vol.712
, pp. 225-235
-
-
Sparreboom, A.1
De Bruijn, P.2
De Jonge, M.J.A.3
-
33
-
-
0002963473
-
Quantitation of platinum-DNA binding after therapeutic levels of drug exposure: A novel use of graphite furnace spectrometry
-
Reed E, Sauerhoff S, Poirier MC: Quantitation of platinum-DNA binding after therapeutic levels of drug exposure: A novel use of graphite furnace spectrometry. Atom Spectr 9:93-95, 1988
-
(1988)
Atom Spectr
, vol.9
, pp. 93-95
-
-
Reed, E.1
Sauerhoff, S.2
Poirier, M.C.3
-
34
-
-
0028901405
-
Current sample handling methods for measurement of platinum-DNA-adducts in leukocytes in man lead to discrepant results in DNA-adduct levels and DNA-repair
-
Ma J, Verweij J, Planting AST, et al: Current sample handling methods for measurement of platinum-DNA-adducts in leukocytes in man lead to discrepant results in DNA-adduct levels and DNA-repair. Br J Cancer 71:512-517, 1995
-
(1995)
Br J Cancer
, vol.71
, pp. 512-517
-
-
Ma, J.1
Verweij, J.2
Planting, A.S.T.3
-
35
-
-
0029974518
-
Comparison of ethanol plasma protein precipitation with plasma ultranltration and trichloroacetic acid protein precipitation for the measurement of unbound platinum concentration
-
Ma J, Stoter G, Verweij J, et al: Comparison of ethanol plasma protein precipitation with plasma ultranltration and trichloroacetic acid protein precipitation for the measurement of unbound platinum concentration. Cancer Chemother Pharmacol 38:391-394, 1996
-
(1996)
Cancer Chemother Pharmacol
, vol.38
, pp. 391-394
-
-
Ma, J.1
Stoter, G.2
Verweij, J.3
-
36
-
-
0031785256
-
Irinotecan (CPT-11) metabolism and disposition in cancer patients
-
Sparreboom A, de Jonge MJA, De Bruijn P, et al: Irinotecan (CPT-11) metabolism and disposition in cancer patients. Clin Cancer Res 4:2747-2754, 1998
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2747-2754
-
-
Sparreboom, A.1
De Jonge, M.J.A.2
De Bruijn, P.3
-
37
-
-
0030038773
-
Relationship between the exposure to cisplatin, DNA-adduct formation in leukocytes and tumour response in patients with solid tumours
-
Schellens JHM, Ma J, Planting AST, et al: Relationship between the exposure to cisplatin, DNA-adduct formation in leukocytes and tumour response in patients with solid tumours. Br J Cancer 73:1569-1575, 1996
-
(1996)
Br J Cancer
, vol.73
, pp. 1569-1575
-
-
Schellens, J.H.M.1
Ma, J.2
Planting, A.S.T.3
-
38
-
-
0033987392
-
Pharmacokinetic, metabolic, and pharmacodynamic profiles in a dose-escalating study of irinotecan and cisplatin
-
de Jonge MJA, Verweij J, de Bruijn P, et al: Pharmacokinetic, metabolic, and pharmacodynamic profiles in a dose-escalating study of irinotecan and cisplatin. J Clin Oncol 18:195-203, 2000
-
(2000)
J Clin Oncol
, vol.18
, pp. 195-203
-
-
De Jonge, M.J.A.1
Verweij, J.2
De Bruijn, P.3
-
39
-
-
10544249871
-
Sequences of topotecan and cisplatin: Phase I, pharmacologic, and in vitro studies to examine sequence dependence
-
Rowinsky EK, Kaufmann SH, Baker SD, et al: Sequences of topotecan and cisplatin: Phase I, pharmacologic, and in vitro studies to examine sequence dependence. J Clin Oncol 14:3074-3084, 1996
-
(1996)
J Clin Oncol
, vol.14
, pp. 3074-3084
-
-
Rowinsky, E.K.1
Kaufmann, S.H.2
Baker, S.D.3
-
40
-
-
0032585232
-
Randomised trial of irinotecan plus supportive care versus supportive care alone after failure for patients with metastatic colorectal cancer
-
Cunningham D, Pyrhönen S, James RD, et al: Randomised trial of irinotecan plus supportive care versus supportive care alone after failure for patients with metastatic colorectal cancer. Lancet 352:1413-1418, 1998
-
(1998)
Lancet
, vol.352
, pp. 1413-1418
-
-
Cunningham, D.1
Pyrhönen, S.2
James, R.D.3
-
41
-
-
0032585197
-
Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer
-
Rougier P, Van Cutsem E, Bajetta E, et al: Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet 352:1407-1412, 1998
-
(1998)
Lancet
, vol.352
, pp. 1407-1412
-
-
Rougier, P.1
Van Cutsem, E.2
Bajetta, E.3
-
42
-
-
0028022585
-
Metabolic fate of irinotecan in humans: Correlation of glucuronidation with diarrhea
-
Gupta E, Lestingi TM, Mick R, et al: Metabolic fate of irinotecan in humans: Correlation of glucuronidation with diarrhea. Cancer Res 54:3723-3725, 1994
-
(1994)
Cancer Res
, vol.54
, pp. 3723-3725
-
-
Gupta, E.1
Lestingi, T.M.2
Mick, R.3
-
43
-
-
0030856521
-
Pharmacokinetic interrelationships of irinotecan (CPT-11) and its three major metabolites in patients enrolled in phase I/II trials
-
Rivory LP, Haaz MC, Canal P, et al: Pharmacokinetic interrelationships of irinotecan (CPT-11) and its three major metabolites in patients enrolled in phase I/II trials. Clin Cancer Res 3:1261-1266, 1997
-
(1997)
Clin Cancer Res
, vol.3
, pp. 1261-1266
-
-
Rivory, L.P.1
Haaz, M.C.2
Canal, P.3
-
44
-
-
0010917253
-
Pharmacokinetics and pharmacodynamics of irinotecan during a phase II clinical trial in colorectal cancer
-
Canal P, Gay C, Dezeuze A, et al: Pharmacokinetics and pharmacodynamics of irinotecan during a phase II clinical trial in colorectal cancer. J Clin Oncol 14:2688-2695, 1996
-
(1996)
J Clin Oncol
, vol.14
, pp. 2688-2695
-
-
Canal, P.1
Gay, C.2
Dezeuze, A.3
|