The feedback response of Escherichia coli rRNA synthesis is not identical to the mechanism of growth rate-dependent control

Journal of Bacteriology

Volumn 182, Issue 2, 2000, Pages 536-539

  Voulgaris, Justina ^a   Pokholok, Dmitry ^b,d   Holmes, W Mike ^b   Squires, Craig ^c   Squires, Catherine L ^c  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOSIDE TRIPHOSPHATE; RIBOSOME RNA;

ARTICLE; BACTERIAL GROWTH; ESCHERICHIA COLI; FEEDBACK SYSTEM; GENE DOSAGE; GROWTH RATE; NONHUMAN; PRIORITY JOURNAL; RNA SYNTHESIS;

BETA-GALACTOSIDASE; ESCHERICHIA COLI; FEEDBACK; GENE DOSAGE; LYSOGENY; MUTATION; OPERON; PROMOTER REGIONS (GENETICS); RNA, BACTERIAL; RNA, RIBOSOMAL;

EID: 0033988002     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.182.2.536-539.2000     Document Type: Article

References (18)

1. Baracchini, E., and H. Bremer. 1991. Control of rRNA synthesis in Escherichia coli at increased rm gene dosage. J. Biol. Chem. 266:11753-11760.
2. Bartlett, M. S., and R. L. Gourse. 1994. Growth rate-dependent control of the rmB P1 core promoter in Escherichia coli. J. Bacteriol. 176:5550-5564.
3. Cole, J. R., C. L. Olsson, J. W. B. Hershey, M. Grunberg-Manago, and M. Nomura. 1987. Feedback regulation of rRNA synthesis in Escherichia coli: requirement for initiation factor IF2. J. Mol. Biol. 198:383-392.
4. Condon, C., S. French, C. Squires, and C. L. Squires. 1993. Depletion of functional ribosomal RNA operons in Escherichia coli causes increased expression of the remaining intact copies. EMBO J. 12:4305-4315.
5. Condon, C., C. Squires, and C. L. Squires. 1995. Control of rRNA transcription in Escherichia coli. Microbiol. Rev. 59:623-645.
6. Dickson, R. R., T. Gaal, H. A. deBoer, P. L. deHaseth, and R. L. Gourse. 1989. Identification of promoter mutants defective in growth-rate-dependent regulation of rRNA transcription in Escherichia coli. J. Bacteriol. 171:4862-4870.
7. Gaal, T., J. Barkei, R. R. Dickson, H. A. deBoer, P. L. deHaseth, H. Alavi, and R. L. Gourse. 1989. Saturation mutagenesis of an Escherichia coli rRNA promoter and initial characterization of promoter variants. J. Bacteriol. 171: 4852-4861.
8. Gaal, T., and R. L. Course. 1990. Guanosine 3′-diphosphate 5′-diphosphate is not required for growth rate-dependent control of rRNA synthesis in Escherichia coli. Proc. Natl. Acad. Sci. USA 87:5533-5537.
9. Gaal, T., M. S. Bartlett, W. Ross, C. L. Turnbough, Jr., and R. L. Gourse. 1997. Transcription regulation by initiating NTP concentration: rRNA synthesis in bacteria. Science 278:2092-2097.
10. Gourse, R. L., H. A. de Boer, and M. Nomura. 1986. DNA determinants of rRNA synthesis in E. coli: growth rate dependent regulation, feedback inhibition, upstream activation, antitermination. Cell 44:197-205.
11. Gourse, R. L., T. Gaal, M. S. Bartlett, J. A. Appleman, and W. Ross. 1996. rRNA transcription and growth rate-dependent regulation of ribosome synthesis in Escherichia coli. Annu. Rev. Microbiol. 50:645-677.
12. Jinks-Robertson, S., R. L. Gourse, and M. Nomura. 1983. Expression of rRNA and tRNA genes in Escherichia coli: evidence for feedback regulation by products of rRNA operons. Cell 33:865-876.
13. Little, R., and H. Bremer. 1982. Quantification of guanosine 5′,3′-bisdiphosphate in extracts from bacterial cells by ion-pair reverse phase high performance liquid chromatography. Anal. Biochem. 126:381-388.
14. Maalöe, O., and N. O. Kjeldgaard. 1996. In control of macromolecular synthesis: a study of DNA, RNA, and protein synthesis in bacteria. Benjamin, New York, N.Y.
15. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
16. Powell, B. S., D. L. Court, Y. Nakamura, M. P. Rivas, and C. L. Turnbough, Jr. 1994. Rapid confirmation of single copy lambda prophage integration by PCR. Nucleic Acids Res. 22:5765-5766.
17. Sharrock, R. A., R. L. Gourse, and M. Nomura. 1985. Defective antitermination of rRNA transcription and derepression of rRNA and tRNA synthesis in the musB5 mutant of Escherichia coli. Proc. Natl. Acad. Sci. USA 82: 5275-5279.
18. Voulgaris, J., S. French, R. L. Gourse, C. Squires, and C. L. Squires. 1999. Increased rm gene dosage causes intermittent transcription of rRNA in Escherichia coli. J. Bacteriol. 181:4170-4175.