Detection and clinical significance of lymph node micrometastasis determined by reverse transcription-polymerase chain reaction in patients with esophageal carcinoma

Oncology

Volumn 58, Issue 1, 2000, Pages 38-44

  Kijima, Fumio ^a   Natsugoe, Shoji ^a   Takao, Sonshin ^a   Aridome, Kuniaki ^a   Baba, Masamichi ^a   Yoshifumi, Matsushita ^a   Eizuru, Yoshito ^a   Aikou, Takashi ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

CEA; Esophageal cancer; Immunohistochemistry; Micrometastasis; Reverse transcription polymerase chain reaction

Indexed keywords

ANTIBODY; CARCINOEMBRYONIC ANTIGEN; CYTOKERATIN; MESSENGER RNA;

ADULT; AGED; ARTICLE; CANCER RECURRENCE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ESOPHAGUS CARCINOMA; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOLOGY; LYMPH NODE METASTASIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0033987895     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000012077     Document Type: Article

References (30)

1. Siewert JR, Roder JD: Lymphadenectomy in esophageal cancer surgery. Dis Esoph 1992;2: 91-97.
2. Roder JD, Busch R, Stein JH, Fink U, Siewert JR: Ratio of invaded to removed lymph nodes as a predietor of survival in squamous cell carcinoma of the esophagus. Br J Surg 1994;81: 410-413.
3. Akiyama H, Tsurumaru M, Udagawa H, Kajiyama Y: Radical lymph node dissection for cancer of the thoracic esophagus. Ann Surg 1994;220:364-372.
4. Baba M, Aikou T, Yoshinaka H, Natsugoe S, Shimazu H, Akazawa K: Long-term results of subtotal csophagectomy with three-field lymphadenectomy for cacinoma of the thoracic esophagus. Ann Surg 1994;219:310-316.
5. Natsugoe S, Shimazu H, Baba M, Yoshinaka H, Shimada M, Haraguchi Y, Shirano K, Tanabe G. Fukumoto T, Aikou T: Recurrence to thoracic esophageal cancer after lymph node dissection in three areas - With special reference to the relationship between recurrence and the number of metastatic lymph nodes. Jpn J Gastroenterol Surg 1991;24:2888-2893.
6. Chen ZL, Perez S, Holmes EC, Wang HJ, Coulson WF, Wen DR, Cochrann AJ: Frequency and distribution of occult micrometastasis in lymph nodes of patients with non-small-cell lung carcinoma. J Natl Cancer Inst 1993;85: 493-498.
7. Siewert JR, Kestlmeier R, Busch R, Böttcher K, Roder JD, Mueller J, Fellbaum C, Höfler H: Benefits of D2 lymph node dissection for patients with gastric cancer and pN0 and pN1 lymph node metastases. Br J Surg 1996;83: 1144-1147.
8. Ishida K, Katsuyama T, Sugiyama A, Kawasaki S: Immunohistochemical evaluation of lymph node micrometastases from gastric carcinomas. Cancer 1997;79:1069-1076.
9. Passlick B, Izbicki JR, Kubuschok B, Nathrath W, Thetter O, Pickmeier U, Schweiberer L, Riethmuller G, Pantel K: Immunohistochemical assessment of individual tumor cells in lymph nodes with non-small-cell lung cancer. J Clin Oncol 1994;12:1827-1832.
10. Davidson BR, Sams VR, Styles J, Deane C, Boulous PB: Detection of occult nodal metastases in patients with colorectal carcinoma. Cancer 1990;65:967-970.
11. Cordell J, Richardson TC, Pulford KAF, Ghosh AK, Gatter KG, Heyderman E, Mason DY: Production of monoclonal antibodies against human epithelial membrane antigen for use in diagnostic immunocytochemistry. Br J Cancer 1985;52:347-354.
12. Hainsworth PJ. Tjandra JJ, Stillwell RG, Machet D, Henderson MA, Rennie GC, McKenzie IF, Bennett RC: Detection and significance of occult metastases in node-negative breast cancer. Br J Surg 1993;80:459-463.
13. Schoenfeld A, Luqmani Y, Sinnett HD, Shousha S, Coombes RC: Keratin 19 mRNA measurement to detect micrometastascs in lymph nodes in breast cancer patients. Br J Cancer 1996;74:1639-1642.
14. Noguchi S, Hiratsuka M, Furukawa H, Aihara T. Kasugai T, Tamura S. Imaoka S, Koyama H, Iwanaga T: Detection of gastric cancer micrometastasis in lymph nodes by amplification of keratin 19 mRNA with reverse transcriptase-polymerase chain reaction. Jpn J Cancer Res 1996;87:650-654.
15. Dorudi S. Kinrade E, Marshal NC, Feakins R, Williams NS, Bustin SA: Genetic detection of lymph node micrometastases in patients with colorectal cancer. Br J Surg 1998;85:98-100.
16. Wong LS, Cantrill JE, Odogwu S, Morris AG, Fraser IA: Detection of circulating tumor cells and nodal metastasis by reverse transcriptase-polymerase chain reaction technique. Br J Surg 1997;84:834-839.
17. Mori M, Mimori K, Inoue H, Barnard GF, Tsuji K, Nanbara S, Ueo H, Akiyoshi T: Detection of cancer micrometastasis in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res 1995;55:3417-3420.
18. Hayashi N, Arakawa H, Nagase H, Yanagisawa A, Kato Y, Ohta H, Takano S, Ogawa M, Nakamura Y: Genetic diagnosis identifies occult lymph node metastasis undetectable by the histopathological method. Cancer Res 1994;54: 3853-3856.
19. Tamagawa E, Ueda M, Takahashi S, Sugano K, Uematsu S, Mukai M, Ogata Y, Kitajima M: Pancreatic lymph nodal and plexus micrometastascs detected by enriched polymerase chain reaction and nonradioisotopic single-strand conformation polymorphism analysis: A new predictive factor for recurrent pancreatic carcinoma. Clin Cancer Res 1997;3:2143-2149.
20. Nishihira T, Hashimoto Y, Katayama M, Mori S, Kuroki T: Molecular and cellular Features of esophageal cancer cells. J Cancer Res Clin Oncol 1993;119:441-449.
21. Gerhard M, Juhl H, Kalthoff H, Schreiber HW, Neumaier M: Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction. J Clin Oncol 1994;12:725-729.
22. International (Ludwig) Breast Cancer Study Group: Prognostic importance of occult axillary lymph node micrometastases from breast cancers. Lancet 1990;335:1565-1568.
23. Natsugoe S, Aikou T, Shimazu H: A detailed histological study on occult metastasis of the lymph nodes. Jpn J Surg 1991;21:528-532.
24. Isozaki H, Okajima K, Fujii K: Histological evaluation of lymph node metastasis on serial sectioning in gastric cancer with radical lymph-adenectomy. Hepatogastroenterology 1997;44: 1133-1136.
25. Dcguchi T. Doi T, Ehara H, Ito S, Takahashi Y, Nishino Y, Fujihiro S, Kawamura T, Komeda H, Horie M, Kaji H, Shimokawa K, Tanaka T, Kawada Y: Detection of micrometastatic prostate cancer cells in lymph nodes by reverse transcriptase-polymerase chain reaction. Cancer Res 1993;53:5350-5354.
26. Wang X, Heller R, Vanvoorhis N, Cruse CW, Glass F, Fenske N, Berman C, Leo-Messina J, Rappaport D, Wells K, DeConti R, Moscinski L, Stankard C, Puleo C, Douglas R: Detection of submicroscopic lymph node metastases with polymerase chain reaction in patients with malignant melanoma. Ann Surg 1994;220:768-774.
27. Puud P, Fodstad O, Hovig E: Identification of a novel cytokeratin 19 pseudogene that may interfere with reverse transcriptase-polymerase chain reaction assays used to detect micrometastatic tumor cells. Int J Cancer 1999;80:119-125.
28. Mori M, Mimori K, Ueo H, Tsuji K, Shiraishi T, Barnard GF, Sugimachi K, Akiyoshi T: Clinical significance of molecular detection of carcinoma cells in lymph nodes and peripheral blood by reverse transcription-polymerase chain reaction in patients with gastrointestinal or breast carcinomas. J Clin Oncol 1998;16:128-132.
29. Izbicki JR, Hosch SB, Pichlmeier U, Rehders A, Busch C, Niendorf A, Passlick B, Broelsch CE, Pantel K: Prognostic value of immunohistochemically identifiable tumor cells in lymph nodes of patients with completely resected esophageal cancer. N Engl J Med 1997;337: 1188-1194.
30. Natsugoe S, Mueller J, Stein JS, Feith M, Höfler H, Siewert JR: Micrometastasis and tumor cell microinvolvement of lymph nodes in esophageal squamous cell carcinoma: Frequency, associated tumor characteristics and impact on prognosis. Cancer 1998;83:858-866.