Energy-dependent nuclear binding dictates metallothionein localization

Journal of Cellular Physiology

Volumn 182, Issue 1, 2000, Pages 69-76

  Woo, Elizabeth S ^a,c   Dellapiazza, Dana ^a   Wang, Angela S ^a   Lazo, John S ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c Cellomics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CADMIUM; CALMODULIN; CARBOCYANINE; CELL EXTRACT; CYANINE DYE 3; FLUORESCENT DYE; METALLOTHIONEIN; WHEAT GERM AGGLUTININ;

ANIMAL; ARTICLE; CELL LINE; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; CHEMISTRY; COLD; CYTOSOL; DIFFUSION; DRUG EFFECT; ENERGY METABOLISM; GLYCOSYLATION; HUMAN; METABOLISM; MOUSE; PROTEIN BINDING; TRANSPORT AT THE CELLULAR LEVEL;

ADENOSINE TRIPHOSPHATE; ANIMALS; BIOLOGICAL TRANSPORT; CADMIUM; CALMODULIN; CARBOCYANINES; CELL EXTRACTS; CELL LINE; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; COLD; CYTOSOL; DIFFUSION; ENERGY METABOLISM; FLUORESCENT DYES; GLYCOSYLATION; HUMANS; METALLOTHIONEIN; MICE; PROTEIN BINDING; WHEAT GERM AGGLUTININS;

EID: 0033987344     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(200001)182:1<69::AID-JCP8>3.0.CO;2-9     Document Type: Article

References (14)

1. Adam SA, Sterne-Marr R, Gerace L. 1990. Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. J Cell Biol 111:807-816.
2. Banerjee D, Onosaka S, Cherian MG. 1982. Immunohistochemical localization of metallothionein in cell nucleus and cytoplasm of rat liver and kidney. Toxicology 24:95-105.
3. Bonner WM. 1975. Protein migration into nuclei. II. Frog oocyte nuclei accumulate a class of microinjected oocyte nuclear proteins and exclude a class of microinjected oocyte cytoplasmic proteins. J Cell Biol 64:31-437.
4. Breeuwer M, Goldfarb DS. 1990. Facilitated nuclear transport of histone HI and other small nucleophilic proteins. Cell 60:99-1008.
5. Davis LI, Blobel G. 1986. Identification and characterization of a nuclear pore complex protein. Cell 45:99-709.
6. De Robertis EM. 1983. Nucleocytoplasmic segregation of proteins and RNAs. Cell 32:1021-1025.
7. Dingwall C, Sharnick SV, Laskey RA. 1982. A polypeptide domain that specifies migration of nucleoplasmin into the nucleus. Cell 30:449-458.
8. Dworetzky SI, Lanford RE, Feldherr CM. 1988. The effects of variations in the number and sequence of targeting signals on nuclear uptake. J Cell Biol 107:1279-1287.
9. Feldherr CM, Ogburn JA. 1980. Mechanism for the selection of nuclear polypeptides in Xenopus oocytes. II. Two-dimensional gel analysis. J Cell Biol 87:589-593.
10. Finlay DR, Newmeyer DF, Price TM, Forbes DJ. 1987. Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores. J Cell Biol 104:189-200.
11. Goldfarb DS, Gariepy J, Schoolnik G, Kornberg RD. 1986. Synthetic peptides as nuclear localization signals. Nature 322:641-644.
12. Gorlich D, Mattaj IW. 1996. Nucleocytoplasmic transport. Science 271:1513-1518.
13. Henkel T, Zabel U, van Zee K, Muller JM, Fanning E, Baeuerle P. 1992. Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kB subunit Cell 68:1121-1133.
14. Kalderon D, Roberts BL, Richardson WD, Smith AE. 1984. A short amino acid sequence able to specify nuclear location. Cell 39:499-509.