Identification of exon-deleted progesterone receptor mRNAs in human uterine endometrial cancers

Oncology

Volumn 58, Issue 1, 2000, Pages 60-65

  Misao, Ryou ^a   Nakanishi, Yoshihito ^a   Sun, Wen Shu ^a   Iwagaki, Shigenori ^a   Fujimoto, Jiro ^a   Tamaya, Teruhiko ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Endometrial cancers, uterine; mRNA variant; Progesterone receptor

Indexed keywords

DNA; MESSENGER RNA; PROGESTERONE RECEPTOR;

ADENOCARCINOMA; ADULT; ARTICLE; BINDING SITE; CLINICAL ARTICLE; DNA SEQUENCE; ENDOMETRIUM CANCER; EXON; FEMALE; GENE DELETION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; RECEPTOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0033986619     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000012080     Document Type: Article

References (29)

1. Tseng L, Gurpide E: Effect of progestins on estradiol receptor levels in human endometrium. J Clin Endocrinol Metab 1975;41:402-404.
2. Tseng L, Gurpide E: Induction of human endometrial estradiol dehydrogenase by progestins. Endocrinology 1975;97:825-833.
3. Tseng L, Lui HC: Stimulation of arylsulfotransferase activity by progestins in human endometrium in vitro. J Clin Endocrinol Mctab 1981; 53:418-421.
4. Bokhman JV: Two pathologenetic types of endometrial carcinoma. Gynecol Oncol 1983;15 10-17.
5. Kelley RM, Baker WH: The role of progesterone in human endometrial cancer. Cancer Res 1965;25:1190-1192.
6. Reifenstein EC: The treatment of advanced endometrial cancer with hydroxyprogesterone caproate. Gynecol Oncol 1974;2:377-414.
7. Kauppila AJ, Isotalo HE, Kivinen ST, Vihko RK: Prediction of clinical outcome with estrogen and progesterone receptor concentrations and their relationships to clinical and histopathological variables in endometrial cancer. Cancer Res 1986;46:5380-5384.
8. Gurpide E: Endometrial cancer: Biochemical and clinical correlates. J Natl Cancer Inst 1991; 83:405-416.
9. Horwitz KB, Alexander PS: In situ photolinked nuclear progesterone receptorsof human breast cancer cells: Subunit molecular weights after transformation and translocation. Endocrinology 1983;113:2195-2201.
10. Conneely OM, Maxell BL, Toft DO, Schrader WT, O'Malley BW: The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA. Biochem Biophys Res Commun 1987; 149:493-501.
11. Fujimoto J, Ichigo S, Hori M, Nishigaki M, Tamaya T: Expression of progesterone receptor form A and B mRNAs in gynecologic malignant tumors. Tumor Biol 1995;16:254-260.
12. Mangal RK, Wiehle RD, Poindexer AN III, Weigel NL: Differential expression of uterine progesterone receptor forms A and B during the menstrual cycle. J Steroid Biochem Mol Biol 1997;63:195-202.
13. Wei LL, Miner R: Evidence for the existence of a third progesterone receptor protein in human breast cancer cell line T47D. Cancer Res 1994; 54:340-343.
14. Kastner P, Krust A, Turcotte B, Stropp U, Tora L, Gronemeyer H, Chambon P: Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J 1990;9:1603-1614.
15. Leygue E, Dotzlaw H, Watson PH, Murphy LC: Identification of novel exon-deleted progesterone receptor variant mRNAs in human breast tissue. Biochem Biophys Res Commun 1996;228:63-68.
16. Richer JK, Lange CA, Wierman AM, Brooks KM, Tung L, Takimoto GS, Horwitz KB: Progesterone receptor variants found in breast cells repress transcription by wild-type receptors. Breast Cancer Res Treat 1998;48:231-241.
17. Misao R, Nakanishi Y, Sun WS, Iwagaki S, Fujimoto J, Tamaya T: Identification of various exon-deleted progesterone receptor messenger ribonucleic acids in human endometrium and ovarian endometriosis. Biochem Biophys Res Commun 1998;252:302-306.
18. The FIGO Committee: FIGO News: Corpus cancer staging. Int J Gynaecol Obstet 1989;28: 189-193.
19. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
20. Misrahi M, Venencie PY, Saugier-Veber P, Sar S, Dessen P, Milgrom E: Structure of the human progesterone receptor gene. Biochim Biophys Acta 1993;1216;289-292.
21. Tung L, Mohamed MK, Hoeffler JP, Takimoto GS, Horwitz KB: Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and arc dominantly inhibited by A-receptors. Mol Endocrinol 1993;7:1256-1265.
22. Vegote E, Shabaz MM, Wen DX, Goldman ME, O'Malley BW, McDonnell DP: Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. Mol Endocrinol 1993; 7:1244-1255.
23. Pfeffer U, Fecarotta E, Castagnetta L, Vidali G: Estrogen receptor variant messenger RNA lacking exon 4 in estrogen-responsive human breast cancer cell lines. Cancer Res 1993;53: 741-743.
24. Zhang QX, Borg A, Fuqua SAW: An exon 5 deletion variant of the estrogen receptor frequently coexpressed with wild-type estrogen receptor in human breast cancer. Cancer Res 1993;53:5882-5884.
25. Daffada AAI, Dowsett M: Tissue-dependent expression of a novel splice variant of the human oestrogen receptor. J Steroid Biochem Mol Biol 1995;55:413-421.
26. Yeates C, Hunt SMN, Balleine RL, Clarke CL: Characterization of a truncated progesterone receptor protein in breast tumors. J Clin Endocrinol Metab 1998;83:460-467.
27. Misao R, Nakanishi Y, Ichigo S, Hori M, Fujimoto J, Tamaya T: Expression of sex hormone-binding globulin mRNA in human endometrial cancers. J Steroid Biochcm Mol Biol 1995;52: 517-522.
28. Misao R, Nakanishi Y, Fujimoto J, Ichigo S, Hori M, Tamaya T: Expression of corticosteroid-binding globulin mRNA in human uterine endometrial cancers. Steroids 1995;60:720-724.
29. Misao R, Nakanishi Y, Fujimoto J, Tamaya T: Expression of sex hormone-binding globulin exon VII splicing variant mRNA in human uterine endometrial cancers. Cancer Res 1997; 57:5579-5583.