Metabotropic glutamate receptors in acutely isolated hippocampal astrocytes: Developmental changes of mGluR5 mRNA and functional expression

GLIA

Volumn 29, Issue 1, 2000, Pages 70-80

  Cai, Zhaohui ^a   Schools, Gary P ^a   Kimelberg, Harold K ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Astroglia; Calcium imaging; Development; Hippocampus; mGluR5; Single cell RT PCR

Indexed keywords

ADENOSINE TRIPHOSPHATE; ASTROCYTE; CALCIUM; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; HIPPOCAMPUS; MESSENGER RNA; RECEPTOR; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SEROTONIN;

AGING; ALTERNATIVE SPLICING; ANIMALS; ASTROCYTES; CALCIUM; CULTURE MEDIA, SERUM-FREE; DOWN-REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; INTRACELLULAR FLUID; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0033986553     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1136(20000101)29:1<70::AID-GLIA7>3.0.CO;2-V     Document Type: Article

References (38)

1. Bezzi P, Carmignoto G, Pasti L, Vesce S, Rossi D, Rizzini BL, Pozzan T, Volterra A. 1998. Prostaglandins stimulate calcium-dependent glutamate release in astrocytes. Nature 391:281-285.
2. Biber K, Laurie DJ, Berthele A, Sommer B, Tölle TR, Gebicke-Härter PJ, van Calker D, Boddeke HWGM. 1999. Expression and signaling of group I metabotropic glutamate receptors in astrocytes and microglia. J Neurochem 72:1671-1680.
3. Cai Z, Kimelberg HK. 1997. Glutamate receptor-mediated calcium responses in acutely isolated hippocampal astrocytes. Glia 21:380-389.
4. Catania MV, Landwehrmeyer GB, Testa CM, Standaert DG, Penney JB, Young AB. 1994. Metabotropic glutamate receptors are differentially regulated during development. Neuroscience 61:481-495.
5. Conn PJ, Pin J-P. 1996. Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol 37:205-237.
6. Cornell-Bell AH, Thomas PG, Smith SJ. 1990. The excitatory neurotransmitter glutamate causes filopodia formation in cultured hippocampal astrocytes. Glia 3:322-334.
7. 2+ responses in rat primary astrocytes cultures. J Neurosci Res 35:246-256.
8. 1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology 36:265-267.
9. Duffy S, MacVicar BA. 1995. Adrenergic calcium signaling in astrocytes networks within the hippocampal slices. J Neurosci 15:5535-5550.
10. Gallo V, Russell JT. 1995. Excitatory amino acid receptors in glia: different subtypes for distinct functions? J Neurosci Res 42:1-8.
11. 2+ influx into astrocytes. Proc Natl Acad Sci USA 87:3454-3458.
12. Jalonen TO, Margraf RR, Wielt DB, Charniga CJ, Linne M-L, Kimelberg HK. 1997. Serotonin induces inward potassium and calcium currents in rat cortical astrocytes. Brain Res 758:69-82.
13. Joly C, Gomeza J, Brabet I, Curry K, Bockaert J, Pin J-P. 1995. Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluRl. J Neurosci 15:3970-3981.
14. Kang J, Jiang L, Goldman SA, Nedergaard M. 1998 Astrocytes-mediated potentiation of inhibitory synaptic transmission. Nature Neurosci 1:683-692.
15. Kimelberg HK, Cai Z, Rastogi P, Charniga CJ, Goderie S, Dave V, Jalonen TO. 1997. Transmitter-induced calcium responses differ in astrocytes acutely isolated from rat brain and in culture. J Neurochem 68:1088-1098.
16. Kosoka T, Hama K. 1986. Three-dimensional structure of astrocytes in the rat dentate gyrus. J Comp Neurol 249:242-260.
17. Landry CF, Campagnoni AT. 1998. Targeting of mRNAs into neuronal and glial processes: intracellular and extracellular influences. Neuroscientist 4:77-87.
18. Miller S, Cotman CW, Bridges RJ. 1992. 1-Aminocyclopentane-trans-1,3-dicarboxylic acid induces glutamine synthetase activity in cultured astrocytes. J Neurochem 58:1967-1970.
19. Miller S, Romano C, Cotman CW. 1995. Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes. J Neurosci 15:6103-6109.
20. Miller S, Sehati N, Romano C, Cotman CW. 1996. Exposure of astrocytes to thrombin reduces levels of the metabotropic glutamate receptor mGluR5. J Neurochem 67:1435-1447.
21. Newman EA, Zahs KR. 1998. Modulation of neuronal activity by glial cells in the retina. J Neurosci 18:4022-4028.
22. Nicoletti F, Iadarola MJ, Wroblewski JT, Costa E. 1986. Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with a 1-adrenoceptors. Proc Natl Acad Sci USA 83:1931-1935.
23. Pechan PA, Chowdhury K, Gerdes W, Seifert W. 1993. Glutamate induces the growth factors NGF, bFGF, the receptor FGF-R1 and c-fos mRNA expression in rat astrocyte culture. Neurosci Lett 153:111-4.
24. Pin J-P, Duvoisin R. 1995. The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34:1-26.
25. 1. Glia 13:101-112.
26. i in hippocampal astrocytes in situ. J Neurochem 65:1515-1523.
27. Porter JT, McCarthy KD. 1996. Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals. J Neurosci 16:5073-5081.
28. Privat A, Gimenez-Ribotta M, Ridet JL. 1995. Morphology of astrocytes, In: Kettenmann H, Ransom BR, editors. Neuroglia. New York: Oxford University Press, p 1-22.
29. Roberts PJ. 1995. Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): phenylglycine derivatives and other selective antagonists - an update. Neuropharmacology 34:813-819.
30. Romano C, Sesma MA, McDonald CT, O'Malley K, van den Pol AN, Olney JW. 1995. Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain. J Comp Neurol 355:455-469.
31. Romano C, van den Pol AN, O'Malley K. 1996. Enhanced early development expression of the metabotropic glutamate receptor mGluR5 in the rat brain: protein, mRNA splice variants, and regional distribution. J Comp Neurol 367:403-412.
32. Schoepp DD, Goldsworthy J, Johnson BG, Salhoff CR, Baker SR. 1994. 3,5-Dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in rat hippocampus. J Neurochem 63:769-772.
33. Schools GP, Kimelberg HK. 1999. mGluR3 and mGluR5 are the predominant metabotropic glutamate receptor mRNAs expressed in hippocampal astrocytes acutely isolated from young rats. J Neurosci Res 58:533-543.
34. Shao Y, McCarthy KD. 1993. Regulation of astroglial responsiveness to neuroligands in primary culture. Neuroscience 55:991-1001.
35. van den Pol AN, Kogelman L, Ghosh P, Liljelund P, Blackstone C. 1994. Development regulation of the hypothalamic metabotropic glutamate receptor mGluR1. J Neurosci 14:3816-3834.
36. van den Pol AN, Romano C, Ghosh P. 1995. Metabotropic glutamate receptor mGlu5 subcellular distribution and developmental expression in hypothalamus. J Comp Neurol 362:134-150.
37. Winder DG, Conn PJ. 1996. Roles of metabotropic glutamate receptors in glial function and glial-neuronal communication. J Neurosci Res 46:131-137.
38. Ye ZC, Sontheimer H. 1999. Metabotropic glutamate receptor agonists reduce glutamate release from cultured astrocytes. Glia 25:270-281.