The role of osteoprogenitors in vascular calcification

Current Opinion in Nephrology and Hypertension

Volumn 9, Issue 1, 2000, Pages 11-15

  Jakoby IV, Michael G ^a   Semenkovich, Clay F ^a,b  

^a Department of Medicine ^*  (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALKALINE PHOSPHATASE; BISPHOSPHONIC ACID DERIVATIVE; BONE MORPHOGENETIC PROTEIN; CALCITRIOL; COLLAGEN; CYCLIC AMP; DEXAMETHASONE; ESTRADIOL; ESTROGEN; FIBRONECTIN; GLUCOCORTICOID; HYDROXYAPATITE; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; OSTEOCALCIN; OSTEOPONTIN; PARATHYROID HORMONE RELATED PROTEIN; PHOSPHATE; TRANSCRIPTION FACTOR;

ATHEROMA; BLOOD VESSEL CALCIFICATION; ENZYME ACTIVITY; HUMAN; NONHUMAN; PRIORITY JOURNAL; REVIEW; STEM CELL;

ANIMALS; ARTERIES; ARTERIOSCLEROSIS; CALCINOSIS; CARDIOVASCULAR DISEASES; CATTLE; DISEASE MODELS, ANIMAL; HUMANS; MICE; OSTEOBLASTS; OSTEOGENESIS; TUNICA MEDIA;

EID: 0033986502     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041552-200001000-00003     Document Type: Review

References (50)

1. 1 McCarthy J, Palmer F. Incidence and significance of coronary artery calcification. Br Heart J 1974; 36:99-506.
2. 2 Stewart, BF, Siscovick D, Lind BK, et al. Clinical factors associated with calcific aortic valve disease: cardiovascular health study. J Am Coll Cardiol 1997; 29:630-634.
3. 3 Honye J, Mahon DJ, Jain A, White CJ, Ramee SR, Wallis JB, al-Zarka A, Tobis JM. Morphological effects on coronary balloon angioplasty in vivo assessed by intravascular ultrasound imaging. Circulation 1992; 85:1012-1025.
4. 4 Kajinami K, Seki H, Takekoshi N, Mabuchi H. Coronary calcification and coronary atherosclerosis: site by site comparative morphologic study by electron beam computed tomography and coronary angiography. J Am Coll Cardiol 1997; 29:1549-1556.
5. 5 Kreines K, Johnson E, Albrink M, Knatterud G, Levin ME, Lewitan A, et al. The course of peripheral vascular disease in non-insulin-dependent diabetes. Diabetes Care 1985; 8:235-243.
6. 6 Sekiya M, Mukai M, Suzuki M, Ohtani T, Abe M, Matsuoka H, et al. Clinical significance of the calcificaion of coronary arteries in patients with angiographicalty normal coronary arteries. Angiology 1992; 43:401-407.
7. 7 Margolis JR, Chen J, Kong Y, Peter RH, Behar VS, Kisslo JA. The diagnostic and prognostic significance of coronary artery calcification. Radiology 1980; 137:609-616.
8. 8 Detrano RC, Wong ND, Doherty TM, Shavelle R. Prognostic significance of cardiac cinefluoroscopy for coronary calcific deposits in asymptomatic high-risk subjects. J Am Coll Cardiol 1994; 24:354-358.
9. 9 Detrano RC, Wong ND, Doherty TM, Shavelle R. Prognostic significance of coronary calcific deposits in asymptomatic high-risk individuals. Am J Med 1997; 102:344-349.
10. 10 Otto CM, Link BK, Kitzman DW, Gersh BJ, Siscovick DS, et al. Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly. N Engl J Med 1999; 341:142-147. This large clinical study demonstrates aortic sclerosis to affect nearly one-third of elderly patients undergoing echocardiography and to be associated with significant increases in the risks of myocardial infarction and cardiovascular mortality independent of left ventricular outflow obstruction.
11. 11 Virchow R. Cellular pathology: as based upon physiological and pathological histology [in English] (translated by Frank Chance) Dover: New York, 1971. pp. 404-408.
12. 12 Young W, Gofman JW, Tandy R, Malamud N, Waters ES. The quantitation of atherosclerosis I: relationship to artery size. Am J Cardiol 1960; 288-293.
13. 13 Mautner GC, Mautner SL, Froehlich J, Feuerstein IM, Proscham MA, Roberts WC, Doppman JL. Coronary artery calcification: assessment with electron beam CT and histomorphometric correlation. Radiology 1994; 192:619-623.
14. 14 Strong JP, Bhattacharyya AK, Eggen DA, Malcom GT, Newman WP III, Restrepo C. Long-term induction and regression of diet-induced atherosclerotic lesionsin rhesus monkeys, I: morphological and chemical evidence for regression of lesions in the aorta and carotid and peripheral arteries. Arterioscler Thromb 1994; 14:958-965.
15. 15 Schmid K, McSharry WO, Palmeijer CH, Binette JP. Chemical and physicochemical studies on the mineral deposits of the human atherosclerotic aorta. Atherosclerosis 1980; 37:199-210.
16. 16 Tanimura A, McGregor DH, Anderson HC. Matrix vesicles in atherosclerotic calcification. Proc Soc Exp Biol Med 1983; 172:173-177.
17. 17 Fitzpatrick LA, Severson A, Edwards WD, Ingram RT. Diffuse calcification in human coronary arteries: association of osteopontin with atherosclerosis. J Clin Invest 1994; 94:1597-1604.
18. 18 Shanahan CM, Cary NRB, Metcalfe JC, Weissberg PL. High expression of genes for calcification-regulating proteins in human atherosclerotic plaques. J Clin Invest 1994; 93:2393-2402.
19. 19 Mohler ER III, Adam LP, McClelland P, Graham L, Hathaway DR. Detection of Osteopontin in calcified human aortic valves. Arterioscler Thromb Vasc Biol 1997; 17:547-552.
20. 20 Bostrom K, Watson KE, Horn S, Wortham C, Herman IM, Demer LL. Bone morphogenetic protein expression in human atherosclerotic lesions. J Clin Invest 1993; 91:1800-1809.
21. 21 Bostrom K, Watson KE, Stanford WP, Demer LL. Atherosclerotic calcification: relation to developmental osteogenesis. Am J Cardiol 1995; 75:88B-91B.
22. 22 Wozney JM, Rosen V, Celeste AJ, Mitsock LM, Whittiers MJ, Kriz RW, et al. Novel regulators of bone formation: molecular clones and activities. Science 1988; 242:1528-1534.
23. 23 Watson KE, Bostrom K, Ravindranath R, Lam T, Norton B, Demer LL. TGF-β1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify. J Clin Invest 1994; 93:2106-2113.
24. 24 Shioi A, Nishizawa Y, Jono S, Koyama H, Hsoi M, Morii H. β-glycerophosphate accelerates calcification in cultured bovine smooth muscle cells. Arterioscler Thromb Vasc Biol 1995; 15:2003-2009.
25. 25 Stein GS, Lian JB, Stein JL, Van Wijnen AJ, Montecino M. Transcriptional control of osteoblast growth and differentiation. Physiol Reviews 1996; 76:593-629.
26. 26 Tintutt Y, Parhami F, Bostrom K, Jackson SM, Demer LL. cAMP stimulates osteoblast-like differentiation of calcifying vascular cells. J Biol Chem 1998; 273:7547-7553.
27. 27 Watson KE, Parhami F, Shin V, Demer LL. Fibronectin and collagen I matrixes promote calcification of vascular cells in vitro, whereas collagen IV matrix is inhibitory. Arterioscler Thromb Vasc Biol 1998; 18:1964-1971. This study demonstrates that cloned osteoblast-like cells isolated from bovine aorta tunica media produce matrix enriched in collagen I and fibronectin that positively regulates the rate and amount of in vitro calcification.
28. 28 Tanimura A, McGregor DH, Anderson HC. Calcification in atherosclerosis, I: human studies. J Exp Pathol 1986; 2:261-272.
29. 29 Proudfoot D, Skepper JN, Shanahan CM, Weissberg PL. Calcification of human vascular cells in vitro is correlated with high levels of matrix gla protein and low levels of osteopontin expression. Arterioscler Thromb Vasc Biol 1998; 18:379-388.
30. 30 Bosky AL, Maresca M, Ullrich W, Doty SB, Butler WT, Prince CW. Osteopontin-hydroxyapatite interactions in vitro: inhibition of hydroxyapatite formation and growth in a gelatin-gel. Bone Miner 1993; 22:147-159.
31. 31 Ross FP, Chappel J, Alvarez JI, Sander D, Butler WT, Farach-Carson MC, et al. Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin avb3 potentiate bone resorption. J Biol Chem 1993; 268:9901-9907.
32. 32 Wada T, McKee MD, Steitz S, Giachelli CM. Calcification of vascular smooth muscle cell cultures: inhibition by osteopontin. Circ Res 1999; 84:166-178. This in vitro study found that osteopontin inhibits bovine vascular calcification, suggesting that osteopontin at sites of heterotopic calcification actually may represent an adaptation to limit calcification.
33. 33 Price PA, Williamson MK. Primary structure of bovine matrix Gla protein, a new vitamin K-dependent protein. J Biol Chem 1985; 260:14971-14975.
34. 34 Mori K, Shioi A, Jono S, Nishizawa Y, Morii H. Expression of matrix Gla protein (MGP) in an in vitro model of vascular calcification. FEBS Letters 1998; 433:1922.
35. 35 Luo G, Ducy P, McKee MD. Spontaneous calcification of arteries and cartilage in mice lacking matrix Gla protein. Nature 1997; 386:78-81.
36. 36 Detrano RC, Wong ND, French WJ, Tang W, Georgiou D, Young E, et al. Am Heart J 1994; 127:1526-1532.
37. 37 Lehto S, Niskanen L, Suhonen M, Ronnemaa T, Laasko M. Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin dependent diabetes mellitus. Arterioscler Thromb Vasc Biol 1996; 16:978-983.
38. 38 Towler DA, Bidder M, Latifi T, Coleman T, Semenkovich CF. Diet-induced diabetes activates an osteogenic gene regulatory program in the aortas of low density lipoprotein receptor-deficient mice. J Biol Chem 1998; 273:30427-30434.
39. 39 Vlassara H. Advanced glycation end-products and atherosclerosis. Ann Med 1996; 28:419-426.
40. 40 Yamagishi S, Fujimori H, Yonekura H, Tanaka N, Yamamoto H. Advanced glycation endproducts accelerate calcification in microvascular pericytes. Biochem Biophys Res Commun 1999; 258:353-357. This study finds that AGE induce osteoblastic differentiation of vascular pericytes in vitro and may contribute to vascular calcification in diabetes.
41. 41 Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol: modification of low density lipoproteins that increase its atherogenicity. N Engl J Med 1989; 320:915-924.
42. 42 Parhami F, Morrow AD, Balucan J, Leitinger N, Watson AD, Tintut Y, et al. Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation. A possible explanation for the paradox of arterial calcification in osteoporotic patients. Arterioscler Thromb Vasc Biol 1997; 17:680-687.
43. 43 Smith R. Prevention and treatment of osteoporosis: common sense and science coincide. J Bone Joint Surg (Br) 1994; 76:345-347.
44. 44 Stampfer, MJ, Colditz GA, Willett WC, Manson JE, Rosner B, Speizer FE, Hennekens CH. Postmenopausal estrogen therapy and cardiovascular disease: ten-year follow-up from the Nurses' Health Study. N Engl J Med 1991; 325:756-762.
45. 45 Balica M, Bostrom K, Shin V, Tillisch K, Demer LL. Calcifying subpopulation of bovine aortic smooth muscle cells is responsive to 17β-estradiol. Circulation 1997; 95:1954-1960.
46. 46 McLaughlin VV, Hoff JA, Rich S. Relation between hormone replacement therapy in women and coronary artery disease estimated by electron beam tomography. Am Heart J 1997; 134:1115-1119.
47. 47 Shemesh J, Frenkel Y, Leibovitch L, Grossman E, Pines A, Motro M. Does hormone replacement therapy inhibit coronary calcification? Obstet Gynecol 1997; 89:989-992.
48. 48 Cheng SL, Yang JW, Rifas L, Zhang SF, Avioli L. Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethansone. Endocrinology 1994; 134:277-286.
49. 49 Mori K, Shioi A, Jono S, Nishizawa Y, Morii H. Dexamethasone enhances in vitro vascular calcification by promoting osteoblastic differentiation of vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 1999; 19:2112-2118. This study demonstrates that dexamethasone induces genotypic and phenotypic markers of osteoblastic differentiation in a BVSMC model of vascular calcification.
50. 50 Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 1997; 89:747-754.