Anxiety-like behavior in rats: A computational model

Neural Networks

Volumn 13, Issue 1, 2000, Pages 21-29

  Salum, C ^a   Morato, S ^a   Roque Da Silva, A C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Animal navigation; Anxiety modeling; Approach avoidance conflict; Elevated plus maze; Exploratory behavior; Rat

Indexed keywords

LEARNING SYSTEMS; MATHEMATICAL MODELS;

ANIMAL NAVIGATION; ANXIETY MODELING; APPROACH-AVOIDANCE CONFLICT;

NEURAL NETWORKS;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; ARTIFICIAL NEURAL NETWORK; AVERSIVE BEHAVIOR; AVOIDANCE BEHAVIOR; BEHAVIOR; CONFLICT; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; LEARNING; LOCOMOTION; MALE; MAZE TEST; MODEL; NONHUMAN; PRIORITY JOURNAL; RAT; SIMULATION;

ANIMALS; ANXIETY; AVOIDANCE LEARNING; MALE; MAZE LEARNING; MODELS, NEUROLOGICAL; RATS;

EID: 0033982909     PISSN: 08936080     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-6080(99)00099-4     Document Type: Article

References (27)

1. Armony J.L., Cohen J.D., Servan-Schreiber D., LeDoux J.E. An anatomically constrained neural network model of fear conditioning. Behavioral Neuroscience. 109:1995;246-257.
2. Blanchard D.C., Blanchard R.J. Ethoexperimental approaches to the biology of emotion. Annual Reviews of Psychology. 39:1988;43-68.
3. Barnett S. Exploratory behavior. General Psychology. 49:1957;289-311.
4. Cohen J.D., Servan-Schreiber D. Context, cortex, and dopamine: a connectionist approach to behavior and biology in schizophrenia. Psychological Review. 99:1992;45-77.
5. Cruz A.P.M., Frei F., Graeff F.G. Ethopharmacological analysis of rat behavior on the elevated plus-maze. Pharmacology Biochemistry and Behavior. 49:1994;171-176.
6. File S.E. Behavioral detection of anxiolytic action. Elliott J.M., Heal D.J., Marsden C.A. Experimental approaches to anxiety and depression. 1992;Wiley, Chichester.
7. Gluck M.A., Myers C.E. Psychobiological models of hippocampal function in learning and memory. Annual Review of Psychology. 48:1997;481-514.
8. Graeff F.G. Brain defense systems and anxiety. Burrows G.D., Roth M., Noyes R. Handbook of anxiety. The neurobiology of anxiety. 3:1990;307-354 Elsevier, Amsterdam.
9. Graeff F.G. Neuroanatomy and neurotransmitter regulation of defensive behaviors and related emotions in mammals. Brazilian Journal of Medical and Biological Research. 27:1994;811-829.
10. Gray J.A. The psychology of fear and stress. 1987;Cambridge University Press, New York.
11. Gray J.A., Smith P.T. An arousal-decision model for partial reinforcement and discrimination learning. Gilbert R., Sutherland N.S. Animal discrimination learning. 1969;Academic Press, London.
12. Grossberg S., Schmajuk N.A. Neural dynamics of attentionally modulated Pavlovian conditioning: conditioned reinforcement, inhibition, and opponent processing. Psychobiology. 15:1987;95-240.
13. Handley S.L., Mithani S. Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of 'fear'-motivated behavior. Archives of Pharmacology. 327:1984;1-5.
14. Lister R.G. The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology. 92:1987;180-185.
15. Lister R.G. Ethologically based animal models of anxiety disorders. Pharmacology Therapeutics. 46:1990;321-340.
16. Miller N.E. Handbook of experimental psychology. 1951;Wiley, New York.
17. Montgomery K.C. The relation between exploratory behavior and spontaneous alternation in the white rat. Journal of Comparative Physiological Psychology. 44:1951;582-589.
18. Montgomery K.C. The relation between fear induced by novel stimulation and exploratory behavior. Journal of Comparative Physiological Psychology. 48:1955;254-260.
19. Montgomery K.C., Monkman J.A. The relation between fear and exploratory behavior. Journal of Comparative Physiological Psychology. 48:1955;132-136.
20. Pellow S., Chopin P., File S.E., Briley M. Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. Journal of Neuroscience Methods. 14:1985;149-167.
21. Rodgers R.J., Cole J.C. The elevated plus-maze: pharmacology, methodology and ethology. Cooper S.J., Hendrie C.A. Ethology and psychopharmacology. 1994;9-44 Wiley, Chichester.
22. Salum, C., Morato, S., Roque-da-Silva, A.C. (in preparation). Rat exploratory behavior in a totally open and in a totally closed mazes.
23. Schmajuk, N.A. (1994). Behavioral dynamics of escape and avoidance: a neural network approach. Proceedings of the Third International Conference on Simulation of Adaptive Behavior, From Animal to Animats 3 (pp. 118-127).
24. Schmajuk N.A., Gray J.A., Lam Ying-Wan. Latent inhibition: a neural network approach. Journal of Experimental Psychology: Animal Behavior Processes. 22:1996;321-349.
25. Sutton R.S., Barto A.G. Toward a modern theory of adaptive networks: expectation and prediction. Psychological Review. 88:1981;135-170.
26. Treit D., Menard J., Royan C. Anxiogenic stimuli in the elevated plus-maze. Pharmacology, Biochemistry and Behavior. 44:1993;463-469.
27. Treves A. Rats, nets, maps, and the emergence of place cells. Psychobiology. 20:(1):1992;1-8.