Validated method for the therapeutic drug monitoring of flunitrazepam in human serum using liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry with an ion trap detector

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 738, Issue 2, 2000, Pages 437-441

  Darius, Jörg ^a   Banditt, Peter ^a  

^a UNIVERSITY HOSPITAL MAGDEBURG   (Germany)

Author keywords

Flunitrazepam

Indexed keywords

FLUNITRAZEPAM;

ARTICLE; DRUG DETERMINATION; DRUG MONITORING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; TANDEM MASS SPECTROMETRY;

ANTI-ANXIETY AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG MONITORING; FLUNITRAZEPAM; HUMANS; MASS SPECTROMETRY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0033981244     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(99)00546-0     Document Type: Article

References (10)

1. Anglin D., Spears K.L., Hutson H.R. Acad. Emerg. Med. 4:1997;323.
2. Meyer F.P. Int. J. Clin. Pharm. Ther. 32:1994;71.
3. Mattila M.A.K., Larni H.M. Drugs. 20:1980;353.
4. Richardson F.J., Manford M.L.M. Br. J. Anaesth. 51:1979;313.
5. Berthault F., Kintz P., Mangis P. J. Chromatogr. B. 685:1996;383.
6. Joyce J.R., Bal T.S., Ardrey R.E., Stevens H.M., Moffat A.C. Biomed. Mass Spectrom. 11:1984;284.
7. Kleinschnitz M., Herderich M., Schreier P. J. Chromatogr. B. 676:1996;61.
8. Bogusz M.J., Maier R.-D., Krüger K.-D., Früchtnicht W. J. Chromatogr. B. 713:1998;361.
9. Senda N., Kohta K., Toshiaki T., Shizukuishi K., Mimura T., Fujita T., Nakayama M. Biomed. Chromatogr. 9:1995;48.
10. Borrey D., Meyer E., Lambert W., De Leenheer A.P. J. Chromatogr. A. 819:1998;125.