Robust assessment of statistical significance in the use of unbound/intrinsic pharmacokinetic parameters in quantitative structure- pharmacokinetic relationships with lipophilicity

Drug Metabolism and Disposition

Volumn 28, Issue 2, 2000, Pages 103-106

  Davis, Andrew M ^a   Webborn, Peter J H ^a   Salt, David W ^a,b  

^a ASTRAZENECA   (United Kingdom)

^b UNIVERSITY OF PORTSMOUTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALFENTANIL; AMIODARONE; AMLODIPINE; BUPIVACAINE; CYTOCHROME P450 3A4; DILTIAZEM; DISOPYRAMIDE; DOFETILIDE; ERYTHROMYCIN; FELODIPINE; HALOPERIDOL; IMIPRAMINE; LIDOCAINE; NIFEDIPINE; PLASMA PROTEIN; QUININE; TRIAZOLAM;

ARTICLE; CORRELATION FUNCTION; DISTRIBUTION VOLUME; DRUG CLEARANCE; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG STRUCTURE; HUMAN; LIPOPHILICITY; LIVER BLOOD FLOW; LIVER CLEARANCE; PRIORITY JOURNAL; RANDOMIZATION; STATISTICAL ANALYSIS; STRUCTURE ACTIVITY RELATION;

ALGORITHMS; ANIMALS; CHEMISTRY, PHYSICAL; DATA INTERPRETATION, STATISTICAL; LIPIDS; PHARMACOKINETICS; RANDOM ALLOCATION; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

CINCHONA PUBESCENS;

EID: 0033980627     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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