Production and functional characterization of a soluble recombinant form of mouse CD59

Immunology

Volumn 99, Issue 2, 2000, Pages 326-332

  Rushmere, N K ^a   Van Den Berg, C W ^a   Morgan, B P ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD59 ANTIGEN; COBROTOXIN; COMPLEMENT COMPONENT C8; COMPLEMENT COMPONENT C9; COMPLEMENT MEMBRANE ATTACK COMPLEX; COMPLEMENTARY DNA; HISTIDINE; RECOMBINANT PROTEIN;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; ASSAY; CHO CELL; COMPLEMENT INHIBITION; CONTROLLED STUDY; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ANIMALS; ANTIGENS, CD59; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, GEL; COMPLEMENT INACTIVATOR PROTEINS; CRICETINAE; CRICETULUS; HEMOLYSIS; HUMANS; MICE; RATS; RECOMBINANT PROTEINS; SEQUENCE ANALYSIS, PROTEIN; SOLUBILITY; SPECIES SPECIFICITY;

EID: 0033980545     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2000.00936.x     Document Type: Article

References (40)

1. 1. Morgan B.P. & Meri S. (1994) Membrane proteins that protect against complement lysis. Springer Sem Immunopathol 15, 369.
2. 2. Sugita Y., Nakano Y. & Tomita M. (1988) Isolation from human erythrocytes of a new membrane protein which inhibits the formation of complement transmembrane channels. J Biochem 104, 633.
3. 3. Okada H., Nagami Y., Takahashi K. et al. (1989) 20 kDa homologous restriction factor of complement resembles T cell activating protein. Biochem Biophys Res Commun 162, 1553.
4. 4. Holguin M.H., Fredrick L.R., Bernshaw N.J., Wilcox L.A. & Parker C.J. (1989) Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria. J Clin Invest 84, 7.
5. 5. Davies A., Simmons D.L., Hale G. et al. (1989) CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. J Exp Med 170, 637.
6. 6. Meri S., Morgan B.P., Davies A. et al. (1990) Human protectin (CD59), an 18,000,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. Immunology 71, 1.
7. 7. Rollins S.A. & Sims P.J. (1990) The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9. J Immunol 144, 3478.
8. 8. Ninomiya H. & Sims P.J. (1992) The human complement regulatory protein CD59 binds to the alpha-chain of C8 and to the 'b' domain of C9. J Biol Chem 267, 13675.
9. 9. Hansch G.M., Hammer C.H., Vanguri P. & Shin M.L. (1981) Homologous species restriction in lysis of erythrocytes by terminal complement proteins. Proc Natl Acad Sci USA 78, 5118.
10. 10. Hughes T.R., Piddlesden S.J., Williams J.D., Harrison R.A. & Morgan B.P. (1992) Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement. Biochem J 284, 169.
11. 11. Rushmere N.K., Tomlinson S. & Morgan B.P. (1997) Expression of rat CD59: functional analysis confirms lack of species selectivity and reveals that glycosylation is not required for function. Immunology 90, 640.
12. 12. Van Den Berg C.W., Harrison R.A. & Morgan B.P. (1993) The sheep analogue of human CD59: purification and characterization of its complement inhibitory activity. Immunology 78, 349.
13. 13. Van Den Berg C.W., Harrison R.A. & Morgan B.P. (1995) A rapid method for the isolation of analogues of human CD59 by preparative SDS PAGE: application to pig CD59. J Immunol Methods 179, 223.
14. 14. Powell M.B., Marchbank K.J., Rushmere N.K., Van Den Berg C.W. & Morgan B.P. (1997) Molecular cloning, chromosomal localization, expression, and functional characterization of the mouse analogue of human CD59. J Immunol 158, 1692.
15. 15. Van Den Berg C.W. & Morgan B.P. (1994) Complement-inhibiting activities of human CD59 and analogues from rat, sheep, and pig are not homologously restricted. J Immunol 152, 4095.
16. 16. Rushmere N.K., Harrison R.A., Van Den Berg C.W. & Morgan B.P. (1994) Molecular cloning of the rat analogue of human CD59: structural comparison with human CD59 and identification of a putative active site. Biochem J 304, 595.
17. 17. Hinchliffe S.J., Rushmere N.K., Hanna S.M. & Morgan B.P. (1998) Molecular cloning and functional characterization of the pig analogue of CD59: relevance to xenotransplanlation. J Immunol 160, 3924.
18. 18. Rooney I.A. & Morgan B.P. (1992) Characterization of the membrane attack complex inhibitory protein CD59 antigen on human amniotic cells and in amniotic fluid. Immunology 76, 541.
19. 19. Meri S., Waldmann H. & Lachmann P.J. (1991) Distribution of protectin (CD59), a complement membrane attack inhibitor, in normal human tissues. Lab Invest 65, 532.
20. 20. Rooney I.A., Atkinson J.P., Krul E.S. et al. (1993) Physiologic relevance of the membrane attack complex inhibitory protein CD59 in human seminal plasma: CD59 is present on extracellular organelles (prostasomes), binds cell membranes, and inhibits complement-mediated lysis. J Exp Med 177, 1409.
21. 21. Hakulinen J. & Meri S. (1995) Shedding and enrichment of the glycolipid-anchored complement lysis inhibitor protectin (CD59) into milk fat globules. Immunology 85, 495.
22. 22. Sugita Y., Ito K., Shiozuka K. et al. (1994) Recombinant soluble CD59 inhibits reactive haemolysis with complement. Immunology 82, 34.
23. 23. Suzuki H., Yamaji N., Egashira A., Yasunaga K., Sugita Y. & Masuho Y. (1996) Effect of the sugar chain of soluble recombinant CD59 on complement inhibitory activity. FEBS Lett 399, 272.
24. 24. Charreau B., Cassard A., Tesson L. et al. (1994) Protection of rat endothelial cells from primate complement-mediated lysis by expression of human CD59 and/or decay-accelerating factor. Transplantation 58, 1222.
25. 25. Van Den Berg C.W., Williams O.M. & Morgan B.P. (1994) Presence of a dysfunctional form of CD59 on a CD59+ subclone of the U937 cell line. Immunology 81, 637.
26. 26. Laemmli U.K. (1970) Cleavage of structural proteins during the assembly of the head bacteriophage T4. Nature 277, 680.
27. 27. Morrissey J.H. (1981) Silver stains for proteins in polyacrylamide gels: a modified procedure with enhanced uniform sensitivity. Anal Biochem 117, 307.
28. 28. Sugita Y., Nakano Y., Oda E. et al. (1993) Determination of carboxyl-terminal residue and disulfide bonds of MACIF (CD59), a glycosyl-phosphatidylinositol-anchored membrane protein. J Biochem 114, 473.
29. 29. Nakano Y., Tozaki T., Kikuta N. et al. (1995) Determination of the active site of CD59 with synthetic peptides. Mol Immunol 32, 241.
30. 30. Kieffer B., Driscoll P.C., Campbell I.D., Willis A.C., Van Der Merwe P.A. & Davis S.J. (1994) Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins. Biochemistry 33, 4471.
31. 31. Lorenz P., Pepperkok P., Ansorge W. & Pyerin W. (1993) Cell biological studies with monoclonal and polyclonal antibodies against human casein kinase II subunit beta demonstrate participation of the kinase in mitogenic signalling. J Biol Chem 268, 2733.
32. 32. Clausen M., Lamb C.J., Megnet R. & Doerner P.W. (1993) Hormone inducible expression and metal affinity chromatography of recombinant proteins in Saccharomyces cerevisiae. Anal Biochem 212, 537.
33. 33. Magdolen V., Rettenberger P., Lopens A. et al. (1995) Expression of the human urokinase-type plasminogen activator recptor in E. coli and Chinese hamster ovary cells: purification of the recombinant proteins and generation of polyclonal antibodies in chicken. Electrophoresis 16, 813.
34. 34. Yu J., Abagyan R., Dong S., Gilbert A., Nussenzweig V. & Tomlinson S. (1997) Mapping the active site of CD59. J Exp Med 185, 745.
35. 35. Yu J., Dong S., Rushmere N.K., Morgan B.P., Abagyan R. & Tomlinson S. (1997) Mapping the regions of the complement inhibitor CD59 responsible for its species selective activity. Biochemistry 36, 9423.
36. 36. Ninomiya H., Stewart B.H., Rollins S.A., Zhao J., Bothwell A.L. & Sims P.J. (1992) Contribution of the N-linked carbohydrate of erythrocyte antigen CD59 to its complement-inhibitory activity. J Biol Chem 267, 8404.
37. 37. Rudd P.M., Morgan B.P., Wormald M.R. et al. (1997) The glycosylation of the complement regulatory protein, human erythrocyte CD59. J Biol Chem 272, 7229.
38. 38. Bodian D.L., Davis S.J., Morgan B.P. & Rushmere N.K. (1997) Mutational analysis of the active site and antibody epitopes of the complement-inhibitory glycoprotein, CD59. J Exp Med 185, 507.
39. 39. Lehto T., Morgan B.P. & Meri S. (1997) Binding of human and rat CD59 to the terminal complement complexes. Immunology 90, 121.
40. 40. Meri S., Lehto T., Sutton C.W., Tyynela J. & Baumann M. (1996) Structural composition and functional characterization of soluble CD59: heterogeneity of the oligosaccharide and glycophosphoinositol (GPI) anchor revealed by laser-desorption mass spectrometric analysis. Biochem J 316, 923.