Mutational analysis of the active site and antibody epitopes of the complement-inhibitory glycoprotein, CD59

Journal of Experimental Medicine

Volumn 185, Issue 3, 1997, Pages 507-516

  Bodian, Dale L ^a,d   Davis, Simon J ^b   Morgan, B Paul ^c   Rushmere, Neil K ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CD59 ANTIGEN; COMPLEMENT COMPONENT C8; COMPLEMENT COMPONENT C9; COMPLEMENT MEMBRANE ATTACK COMPLEX; EPITOPE; GLUTAMIC ACID; MONOCLONAL ANTIBODY; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CHO CELL; COMPLEMENT SYSTEM; CONTROLLED STUDY; ENZYME ACTIVE SITE; HOST CELL; MOLECULAR RECOGNITION; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD59; BINDING SITES; CHO CELLS; CRICETINAE; DNA MUTATIONAL ANALYSIS; EPITOPES; GLYCOSYLATION; HUMANS; MOLECULAR SEQUENCE DATA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031041068     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.3.507     Document Type: Article

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