Neisseria meningitidis expressing transferrin binding proteins of Actinobacillus pleuropneumoniae can utilize porcine transferrin for growth

Infection and Immunity

Volumn 68, Issue 2, 2000, Pages 550-557

  Litt, David J ^a,c   Palmer, Helen M ^a,d   Borriello, S Peter ^b  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

^b CENTRAL PUBLIC HEALTH LABORATORY   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d BRISTOL ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; IRON; TRANSFERRIN;

ACTINOBACILLUS PLEUROPNEUMONIAE; ARTICLE; BACTERIAL GROWTH; BACTERIUM ISOLATION; BACTERIUM MUTANT; BACTERIUM TRANSFORMATION; IRON KINETICS; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACTINOBACILLUS PLEUROPNEUMONIAE; ANIMALS; CARRIER PROTEINS; GENETIC VECTORS; HUMANS; IRON-BINDING PROTEINS; NEISSERIA MENINGITIDIS; RECOMBINANT PROTEINS; STREPTOMYCIN; SWINE; TRANSFERRIN; TRANSFERRIN-BINDING PROTEINS;

EID: 0033980002     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.2.550-557.2000     Document Type: Article

References (49)

1. Anderson, J. E., P. F. Sparling, and C. N. Cornelissen. 1994. Gonococcal transferrin-binding protein 2 facilitates but is not essential for transferrin utilization. J. Bacteriol. 176:3162-3170.
2. Bell, P. E., C. D. Nau, J. T. Brown, J. Konisky, and R. J. Kadner. 1990. Genetic suppression demonstrates interaction of TonB protein with outer membrane transport proteins in Escherichia coli. J. Bacteriol. 172:3826-3829.
3. Biswas, G. D., J. E. Anderson, and P. F. Sparling. 1997. Cloning and functional characterization of Neisseria gonorrhoea tonB, exbB and exbD genes. Mol. Microhiol. 24:169-179.
4. Boulton, I. C., A. R. Gorringe, N. Allison, A. Robinson, B. Gorinsky, C. L. Joannou, and R. W. Evans. 1998. Transferrin-binding protein B isolated from Neisseria meningitidis discriminates between apo and diferric human transferrin. Biochem. J. 334:269-273.
5. Brodeur, B. R., P. S. Tsang, J. Hamel, Y. Larose, and S. Montplaisir. 1986. Mouse models of infection for Neisseria meningitidis B, 2b and Haemophilus influenzae type b diseases. Can. J. Microbiol. 32:33-37.
6. Calver, G. A., P. Kenny, and G. Lavergne. 1976. Iron as a replacement for mucin in the establishment of meningococcal infection in mice. Can. J. Microbiol. 22:832-838.
7. Carlone, G. M., M. L. Thomas, H. S. Rumschlag, and F. O. Sottnek. 1986. Rapid microprocedure for isolating detergent-insoluble outer membrane proteins from Haemophilus species. J. Clin. Microbiol. 24:330-332.
8. Cornelissen, C. N., J. E. Anderson, and P. F. Sparling. 1997. Energy-dependent changes in the gonococcal transferrin receptor. Mol. Microbiol. 26:25-35.
9. Cornelissen, C. N., G. D. Biswas, and P. F. Sparling. 1993. Expression of gonococcal transferrin-binding protein 1 causes Escherichia coli to bind human transferrin. J. Bacteriol. 175:2448-2450.
10. Cornelissen, C. N., M. Kelley, M. M. Hobbs, J. E. Anderson, J. G. Cannon, M. S. Cohen, and P. F. Sparling. 1998. The transferrin receptor expressed by gonococcal strain FA1090 is required for the experimental infection of human male volunteers. Mol. Microbiol. 27:611-616.
11. Cornelissen, C. N., and P. F. Sparling. 1994. Iron piracy: acquisition of transferrin-bound iron by bacterial pathogens. Mol. Microbiol. 14:843-850.
12. Cornelissen, C. N., and P. F. Sparling. 1996. Binding and surface exposure characteristics of the gonococcal transferrin receptor are dependent on both transferrin-hinding proteins. J. Bacteriol. 178:1437-1444.
13. Dower, W. J., J. F. Miller, and C. W. Ragsdale. 1988. High efficiency transformation of Escherichia coli by high voltage electroporation. Nucleic Acids Res. 16:6127-6145.
14. Fuller, C. A., R. Yu, S. W. Irwin, and A. B. Schryvers. 1998. Biochemical evidence for a conserved interaction between bacterial transferrin binding protein A and transferrin binding protein B. Microb. Pathog. 24:75-87.
15. Genco, C. A., and P. J. Desai. 1996. Iron acquisition in the pathogenic Neisseria. Trends Microbiol. 4:179-184.
16. Gonzalez, G. C., D. L. Caamano, and A. B. Schryvers. 1990. Identification and characterization of a porcine-specific transferrin receptor in Actinobacillus pleuropneumoniae. Mol. Microbiol. 4:1173-1179.
17. Gonzalez, G. C., R. Yu, P. R. Rosteck, and A. B. Schryvers. 1995. Sequence, genetic analysis, and expression of Actinobacillus pleuropneumoniae transferrin receptor genes. Microbiology 141:2405-2416.
18. Gray-Owen, S. D., S. Loosmore, and A. B. Schryvers. 1995. Identification and characterization of genes encoding the human transferrin-hinding proteins from Haemophilus influenzae. Infect. Immun. 63:1201-1210.
19. Gray-Owen, S. D., and A. B. Schryvers. 1996. Bacterial transferrin and lactoferrin receptors. Trends Microbiol. 4:185-191.
20. Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
21. Hart, C. A., and T. R. F. Rogers. 1993. Meningococcal disease. J. Med. Microbiol. 39:3-35.
22. Holbein, B. E. 1980. Iron-controlled infection with Neisseria meningitidis in mice. Infect. Immun. 29:886-891.
23. Irwin, S. W., N. Averil, C. Y. Cheng, and A. B. Schryvers. 1993. Preparation and analysis of isogenic mutants in the transferrin receptor protein genes, tbpA and tbpB from Neisseria meningitidis. Mol. Microbiol. 8:1125-1133.
24. Khun, H. H., S. D. Kirby, and B. C. Lee. 1998. A Neisseria meningitidis fbpABC mutant is incapable of using nonheme iron for growth. Infect. Immun. 66:2330-2336.
25. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
26. Legrain, M., A. Findeli, D. Villeval, M.-J. Quentin-Millet, and E. Jacobs. 1996. Molecular characterization of hybrid Tbp2 proteins from Neisseria meningitidis. Mol. Microbiol. 19:159-169.
27. Legrain, M., V. Mazarin, S. W. Irwin, B. Bouchon, M.-J. Quentin-Millet, E. Jacobs, and A. B. Schryvers. 1993. Cloning and characterization of Neisseria meningitidis genes encoding the transferrin-binding proteins Tbp1 and Tbp2. Gene 130:73-80.
28. Lewis, L. A., E. Gray, Y.-P. Wang, B. A. Roe, and D. W. Dyer. 1997. Molecular characterization of hpuAB, the haemoglobin-haptoglobin-utilization operon of Neisseria meningitidis. Mol. Microbiol. 23:737-749.
29. Loosmore, S. M., Y. Yang, D. C. Coleman, J. M. Shortreed, D. M. England, R. E. Harkess, P. S.-C. Chong, and M. H. Klein. 1996. Cloning and expression of the Haemophilus influenzae transferrin receptor genes. Mol. Microbiol. 19:575-586.
30. Mackinnon, F. G., A. R. Gorringe, S. G. P. Funnell, and A. Robinson. 1992. Intranasal infection of infant mice with Neisseria meningitidis. Microb. Pathog. 12:415-420.
31. Miller, C. P. 1933. Experimental meningococcal infection in mice. Science 78:340-341.
32. Monod, M., C. Denoya, and D. Dubnau. 1986. Sequence and properties of pIM13, a macrolide-lincosamide-streptogramin B resistance plasmid from Bacillus subtilis. J. Bacteriol. 167:138-147.
33. Ogunnariwo, J. A., T. K. Woo, R. Y. C. Lo, G. C. Gonzalez, and A. B. Schryvers. 1997. Characterization of the Pasteurella haemolytica transferrin receptor genes and the recombinant receptor proteins. Microb. Pathog. 23:273-284.
34. Pintor, M., J. A. Gomez, L. Ferron, C. M. Ferreiros, and M. T. Criado. 1998. Analysis of ThpA and TbpB functionality in defective mutants of Neisseria meningitidis. J. Med. Microbiol. 47:757-760.
35. Powell, N. B. L., K. Bishop, H. M. Palmer, D. A. Ala'Aldeen, A. R. Gorringe, and S. P. Borriello. 1998. Differential binding of apo and holo human transferrin to meningococci and co-localisation of the transferrin-hinding proteins (TbpA and TbpB). J. Med. Microbiol. 47:257-264.
36. Renauld-Mongenie, G., M. Latour, D. Poncet, S. Naville, and M.-J. Quentin-Millet. 1998. Both the full-length and the N-terminal domain of the meningococcal transferrin-binding protein B discriminate between iron-loaded and apo-transferrin. FEMS Microbiol. Lett. 169:171-177.
37. Renauld-Mongenie, G., D. Poncet, L. von Olleschik-Elbheim, T. Cournez, M. Mignon, M. A. Schmidt, and M.-J. Quentin-Millet. 1997. Identification of human transferrin-binding sites within meningococcal transferrin-binding protein B. J. Bacteriol. 179:6400-6407.
38. Retzer, M. D., R. Yu, Y. Zhang, G. C. Gonzalez, and A. B. Schryvers. 1998. Discrimination between apo and iron-loaded forms of transferrin by transferrin binding protein B and its N-terminal subfragment. Microb. Pathog. 25:175-180.
39. Robertson, B. D., M. Frosch, and J. P. M. van Putten. 1993. The role of gaIE in the biosynthesis and function of gonococcal lipopolysaccharide. Mol. Microbiol. 8:891-901.
40. Salit, I. E., E. van Melle, and L. Tomalty. 1984. Experimental meningococcal infection in neonatal animals: models for mucosal invasiveness. Can. J. Microbiol. 30:1022-1029.
41. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
42. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
43. Saukkonen, K., and M. Leinonen. 1988. Infant rat model for meningococcal group B infection, p. 815-820. In J. T. Poolman et al. (ed.), Gonococci and meningococci. Kluwer Academic Publishers. Dordrecht, The Netherlands.
44. Schryvers, A. B., and G. C. Gonzalez. 1989. Comparison of the abilities of different protein sources of iron to enhance Neisseria meningitidis infection in mice. Infect. Immun. 57:2425-2429.
45. Schryvers, A. B., and L. J. Morris. 1988. Identification and characterisation of the transferrin receptor from Neisseria meningitidis. Mol. Microbiol. 2:281-288.
46. Sieffert, H. S., and M. So. 1991. Genetic systems in pathogenic Neisseriae. Methods Enzymol. 204:342-357.
47. Stojiljkovic, I., J. Larson, V. Hwa, S. Anic, and M. So. 1996. HmbR outer membrane receptors of pathogenic Neisseria spp.: iron-regulated, hemoglobin-binding proteins with a high level of primary structure conservation. J. Bacteriol. 178:4670-4678.
48. Stojiljkovic, I., and N. Srinivasan. 1997. Neisseria meningitidis tonB, exbB, and exbD genes: Ton-dependent utilization of protein-bound iron in Neisseriae. J. Bacteriol. 179:805-812.
49. Yu, R.-H., and A. B. Schryvers. 1993. The interaction between human transferrin and transferrin binding protein 2 from Moraxella (Branhamella) catarrhalis differs from that of other human pathogens. Microb. Pathog. 15: 443-445.