A molecular genetic system for the pathogenic yeast Candida dubliniensis

Gene

Volumn 242, Issue 1-2, 2000, Pages 393-398

  Staib, Peter ^a   Michel, Sonja ^a   Köhler, Gerwald ^a   Morschhäuser, Joachim ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Controlled gene expression; GFP; Mycophenolic acid resistance; Reporter gene; Selection marker; Transformation

Indexed keywords

GREEN FLUORESCENT PROTEIN; MARKER; MYCOPHENOLIC ACID;

ARTICLE; CANDIDA ALBICANS; CANDIDA DUBLINIENSIS; DRUG RESISTANCE; FLUORESCENCE MICROSCOPY; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GENETIC TRANSFORMATION; NONHUMAN; PARASITE VIRULENCE; PRIORITY JOURNAL; REPORTER GENE;

ASPARTIC ENDOPEPTIDASES; CANDIDA; CANDIDA ALBICANS; CULTURE MEDIA; DRUG RESISTANCE, MICROBIAL; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MYCOPHENOLIC ACID; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; TRANSFORMATION, GENETIC; VIRULENCE;

ANIMALIA; CANDIDA ALBICANS; CANDIDA DUBLINIENSIS;

EID: 0033978738     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00512-0     Document Type: Article

References (27)

1. Anthony R.M., Midgley J., Sweet S.P., Howell S.A. Multiple strains of Candida albicans in the oral cavity of HIV positive and HIV negative patients. Microb. Ecol. Health Dis. 8:1995;23-30.
2. Boerlin P., Boerlin-Petzold F., Durussel C., Addo M., Pagani J.L., Chave J.P., Bille J. Cluster of atypical Candida albicans isolates in a group of human immunodeficiency virus-positive drug users. J. Clin. Microbiol. 33:1995;1129-1135.
3. Fonzi W.A., Irwin M.Y. Isogenic strain construction and gene mapping in Candida albicans. Genetics. 134:1993;717-728.
4. Gilfillan G.D., Sullivan D.J., Haynes K., Parkinson T., Coleman D.C., Gow N.A.R. Candida dubliniensis: phylogeny and putative virulence factors. Microbiology. 144:1998;829-838.
5. Hazen K.C. New and emerging yeast pathogens. Clin. Microbiol. Rev. 8:1995;462-478.
6. Hube B., Monod M., Schofield D.A., Brown A.J.P., Gow N.A.R. Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans. Mol. Microbiol. 14:1994;87-99.
7. Köhler G.A., White T.C., Agabian N. Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid. J. Bacteriol. 179:1997;2331-2338.
8. LeGuennec R., Reynes J., Mallie M., Pujol C., Janbon F., Bastide J.-M. Fluconazole- and itraconazole-resistant Candida albicans strains from AIDS patients: multilocus enzyme electrophoresis analysis and antifungal susceptibilities. J. Clin. Microbiol. 33:1995;2732-2737.
9. Mahrous M., Lott T.J., Meyer S.A., Sawant A.D., Ahearn D.J. Electrophoretic karyotyping of typical and atypical Candida albicans. J. Clin. Microbiol. 28:1990;876-881.
10. McCullough M.J., Ross B.C., Dwyer B.D., Reade P.C. Genotype and phenotype of oral Candida albicans from patients infected with the human immunodeficiency virus. Microbiology. 140:1994;1195-1202.
11. McCullough M., Ross B., Reade P. Characterization of genetically distinct subgroup of Candida albicans strains isolated from oral cavities of patients infected with human immunodeficiency virus. J. Clin. Microbiol. 33:1995;696-700.
12. Millon L., Manteaux A., Reboux G., Drobacheff C., Monod M., Barale T., Michel-Briand Y. Fluconazole-resistant recurrent oral candidiasis in human immunodeficiency virus-positive patients: persistence of Candida albicans strains with the same genotype. J. Clin. Microbiol. 32:1994;1115-1118.
13. Morschhäuser J., Michel S., Hacker J. Expression of a chromosomally integrated, single-copy GFP gene in Candida albicans, and its use as a reporter of gene regulation. Mol. Gen. Genet. 257:1998;412-420.
14. Morschhäuser J., Michel S., Staib P. Sequential gene disruption in Candida albicans by FLP-mediated site-specific recombination. Mol. Microbiol. 32:1999;547-556.
15. Morschhäuser J., Ruhnke M., Michel S., Hacker J. Identification of CARE-2-negative Candida albicans isolates as Candida dubliniensis. Mycoses. 42:1999;29-32.
16. Odds F.C. Candida and Candidosis: a Review and Bibliography. 1988;Bailliere Tindall, London, UK.
17. Pfaller M.A. Nosocomial candidiasis: emerging species, reservoirs and modes of transmission. Clin. Infect. Dis. 22:(suppl. 2):1996;S89-S94.
18. Pla J., Gil C., Monteoliva L., Navarro-Garcia F., Sanchez M., Nombela C. Understanding Candida albicans at the molecular level. Yeast. 12:1996;1677-1702.
19. Plessis A., Dujon B. Multiple tandem integrations of transforming DNA sequences in yeast chromosomes suggest a mechanism for integrative transformation by homologous recombination. Gene. 134:1993;41-50.
20. Santos M.A., Ueda T., Watanabe K., Tuite M. The non-standard genetic code of Candida spp.: an evolving genetic code or a novel mechanism for adaptation? Mol. Microbiol. 26:1997;423-431.
21. Schmid J., Odds F., Wiselka M.J., Nicholson K.G., Soll D.R. Genetic similarity and maintenance of Candida albicans strains from a group of AIDS patients, demonstrated by DNA fingerprinting. J. Clin. Microbiol. 30:1992;935-941.
22. Staib P., Kretschmar M., Nichterlein T., Köhler G., Michel S., Hof H., Hacker J., Morschhäuser J. Host-induced, stage-specific virulence gene activation in Candida albicans during infection. Mol. Microbiol. 32:1999;533-546.
23. Sullivan D., Coleman D. Candida dubliniensis: characteristics and identification. J. Clin. Microbiol. 36:1998;329-334.
24. Sullivan D., Bennett D., Henman M., Harwood P., Flint S., Mulcahy F., Shanley D., Coleman D. Oligonucleotide fingerprinting of isolates of Candida species other than C. albicans and of atypical Candida species from human immunodeficiency virus-positive and AIDS patients. J. Clin. Microbiol. 31:1993;2124-2133.
25. Sullivan D.J., Westerneng T.J., Haynes K.A., Bennett D.E., Coleman D.C. Candida dubliniensis sp. nov.: phenotypic and molecular characterization of a novel species associated with oral candidosis in HIV-infected individuals. Microbiology. 141:1995;1507-1521.
26. White T., Agabian N. Candida albicans secreted aspartyl proteinases: isoenzyme pattern is determined by cell type and levels are determined by environmental factors. J. Bacteriol. 177:1995;5215-5221.
27. Wirsching S., Morschhäuser J. The regulation and role of the MDR1 gene in fluconazole resistance of clinical Candida albicans strains. 39th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco. Abstract band. 1999;585.