Prognostic significance of DNA ploidy, S-phase fraction, and tissue levels of aspartic, cysteine, and serine proteases in operable gastric carcinoma

Clinical Cancer Research

Volumn 6, Issue 1, 2000, Pages 178-184

  Russo, Antonio ^a,d   Bazan, Viviana ^a   Migliavacca, Manuela ^a   Zanna, Ines ^a   Tubiolo, Carla ^a   Tumminello, Francesca Maria ^a   Dardanoni, Gabriella ^c   Cajozzo, Massimo ^a   Bazan, Pietro ^a   Modica, Giuseppe ^a   Latteri, Mario ^a   Tomasino, Rosa Maria ^a   Colucci, Giuseppe ^b   Gebbia, Nicola ^a   Leto, Gaetano ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b NATIONAL CANCER INSTITUTE GIOVANNI PAOLO II   (Italy)

^c Epidemiological Observatory   (Italy)

^d NONE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC PROTEINASE; CYSTEINE PROTEINASE; SERINE PROTEINASE;

ADULT; AGED; ARTICLE; CANCER STAGING; CELL CYCLE S PHASE; DISEASE ASSOCIATION; FEMALE; HISTOPATHOLOGY; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PLOIDY; PRIORITY JOURNAL; PROGNOSIS; STOMACH CARCINOMA;

ADENOCARCINOMA; ADULT; AGED; ASPARTIC ENDOPEPTIDASES; CYSTEINE ENDOPEPTIDASES; DNA, NEOPLASM; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PLOIDIES; PREDICTIVE VALUE OF TESTS; PROBABILITY; PROGNOSIS; S PHASE; SERINE ENDOPEPTIDASES; STOMACH NEOPLASMS; SURVIVAL ANALYSIS; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 0033978424     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Allgayer, H., Heiss, M. M., and Schildberg, F. W. Prognostic factors in gastric cancer. Br. J. Surg., 84: 1651-1664, 1997.
2. Silvestrini, R. Cell kinetics: prognostic and therapeutic implications in human tumours. Cell. Proliferation, 27: 579-596, 1994.
3. Lee, K. H., Lee, J. S., Lee, J. H., Kim, S. W., Suh, C., Kim, W. K., Kim, S. H., Min, Y. I., Kim, B. S., Park, K. C., Lee, M. S., and Sun, H. S. Prognostic value of DNA flow cytometry in stomach cancer: a 5-year prospective study. Br. J. Cancer, 79: 1727-1735, 1999.
4. Yonemura, Y., Ooyama, S., Sugiyama, K., Kamata, T., De Aretxabala, X., Kimura, H., Kosaka, T., Yamaguchi, A., Miwa, K., and Miyazaki, I. Retrospective analysis of the prognostic significance of DNA ploidy patterns and S-phase fraction in gastric carcinoma. Cancer Res., 50: 509-514, 1990.
5. Ohyama, S., Yonemura, Y., and Miyazaki, I. Prognostic value of S-phase fraction and DNA ploidy studied with in vivo administration of bromodeoxyuridine on human gastric cancers. Cancer (Phila.), 65: 116-121, 1990.
6. Abad, M., Ciudad, J., Rincon, M. R., Silva I., Paz-Bouza, J. I., Lopez, A., Alonso, A. G., Bullon, A., and Orfao, A. DNA aneuploidy by flow cytometry is an independent prognostic factor in gastric cancer. Anal. Cell. Pathol., 16: 223-231, 1998.
7. Setala, L. P., Nordling, S., Kosma, V. M., Lipponen, P. K., Eskelinen, M. J., Hollmen, S. M., Syrjanen, K. J., and Alhava, E. M. Comparison of DNA ploidy and S-phase fraction with prognostic factors in gastric cancer. Anal. Quant. Cytol. Histol., 19: 524-532, 1997.
8. Victorzon, M., Roberts, P. J., Haglund, C., von Boguslawsky, K., and Nordling, S. Ki-67 immunoreactivity, ploidy and S-phase fraction as prognostic factors in patients with gastric carcinoma. Oncology, 53: 182-191, 1996.
9. Rochefort, H., Liaudet, E., and Garcia, M. Alterations and role of human cathepsin D in cancer metastasis. Enzyme Protein, 49: 106-116, 1996.
10. Lah, T. T., and Kos, J. Cysteine proteinases in cancer progression and their clinical relevance for prognosis. Biol. Chem., 379: 125-130, 1998.
11. Farinati, F., Herszenyi, L., Plebani, M., Carraro, P., De Paoli, M., Cardin, R., Roveroni, G., Rugge, M., Nitti, D., Grigioni, W. F., D'Errico, A., and Naccarato, R. Increased levels of cathepsin B and L, urokinase-type plasminogen activator and its inhibitor type-1 as an early event in gastric carcinogenesis. Carcinogenesis (Lond.), 17: 2581-2587, 1996.
12. Plebani, M., Herszènyi, L., Cardin, R., Roveroni, G., Carraro, P., Paoli, M. D., Rugge, M., Grigioni, W. F., Nitti, D., Naccarato, R., and Farinati, F. Cysteine and serine proteases in gastric cancer. Cancer (Phila.), 76: 367-375, 1996.
13. Watanabe, M., Higashi, T., Watanabe, A., Osawa, T., Sato, Y., Kimura, Y., Tominaga, S., Hashimoto, N., Yoshida, Y., Morimoto, S., Shiota, T., Hashimoto, M., Kobayashi, M., Tomoda, J., and Tsuji, T. Cathepsin B and L activities in gastric cancer tissue: correlation with histological findings. Biochem. Med. Metab. Biol., 42: 21-29, 1989.
14. Allgayer, H., Babic, R., Grutzner, K. U., Beyer, B. C., Tarabichi, A., Schildberg, W. F., and Heiss, M. M. An immunohistochemical assessment of cathepsin D in gastric carcinoma: its impact on clinical prognosis. Cancer (Phila.), 80: 179-187, 1997.
15. Ganesh, S., Sier, C. F. M., Heerding, M. M., van Krieken, J. H. J. M., Griffioen, G., Welwaart, K., van de Velde, C. J. H., Lamers, C. B. H. W., and Verspaget, H. W. Prognostic value of the plasminogen activation system in patients with gastric carcinoma. Cancer (Phila.), 77: 1035-1043, 1996.
16. Allgayer, H., Babic, R., Grutzner, U., Beyer, B. C. M., Tarabichi, A., Schildberg, F. W., and Heiss, M. M. Tumor-associated proteases and inhibitors in gastric cancer: analysis of prognostic impact and individual risk protease patterns. Clin. Exp. Metastasis, 16: 62-73, 1998.
17. Henskens, Y. M. C., Veerman, E. C. I., and Amerongen, A. V. N. Cystatins in health and disease. Biol. Chem. Hoppe-Seyler, 377: 71-86, 1996.
18. Scott, G. K. Proteinases and proteinase inhibitors in tumor cell growth and metastasis. Cancer J., 10: 80-86, 1997.
19. Abdollahi, A., Getts, L. A., Sonoda, G., Miller, P. D., Taguchi, T., Godwin, A. K., Testa, J. H., and Hamilton, T. C. Genome scanning detects amplification of the cathepsin B gene (CTsB) in transformed rat ovarian surface epithelial cells. J. Gynecol. Invest., 6: 32-40, 1999.
20. Hughes, S. J., Glover, T. W., Zhu, X. X., Kuick, R., Thornual, D., Orringer, M. B., Beer, D. G., and Hananh, S. A novel amplicon at 8p22-23 results in overexpression of cathepsin B in esophageal adenocarcinoma. Proc. Natl. Acad. Sci. USA, 95: 12410-12415, 1998.
21. Bears, O. H., Hensen, D. E., Hutter, R. V. P., and Meyers, M. H. Manual for Staging of Cancer, 3rd ed., pp. 69-71. Philadelphia: J. B. Lippincott, 1988.
22. Russo, A., Bazan, V., Morello, V., Tralongo, V., Nagar, C., Nuara, R., Dardanoni, G., Bazan, P., and Tomasino, R. M. Vimentin expression, proliferating cell nuclear antigen and flow cytometric factors. Anal. Quant. Cytol. Histol., 16: 365-374, 1994.
23. Dean, P. N., and Jett, J. H. Mathematical analysis of DNA distribution derived from flow cytometry. J. Cell Biol., 60: 523-527, 1974.
24. Rabinovitch, P. S. Numerical compensation for the effects of cell clumping on DNA histograms. Cytometry, 4: 27, 1990.
25. Tumminello, F. M., Gebbia, N., Pizzolanti, G., Russo, A., Bazan, V., and Leto, G. Cathepsin D content in colorectal cancer. Correlation with cathepsin D activity and other biological parameters. A Preliminary Report. Oncology, 52: 237-242, 1995.
26. Jerala, R., Zerounik, E., Lohner, K., and Turk, V. Structural basis for the difference in thermodynamic proprieties between the two cysteine proteinase inhibitors human stefin A and B. Protein Eng., 7: 977-984, 1994.
27. Kaplan, E. L., and Meier, P. Non parametric estimation for incomplete observations. J. Am. Stat. Assoc., 53: 457-481, 1958.
28. Peto, R., Pike, M. C., Armitage, P., Breslow, N. E., Cox, D. R., Howard, S. V., Mantel, N., McPherson, K., Peto, J., and Smith, P. G. Design and analysis of randomized clinical trials requiring prolonged observation of each patients. II. Analysis and examples. Br. J. Cancer, 35: 1-39, 1977.
29. Cox, D. R. Regression models and life tables. J. R. Stat. Soc., 34: 187-220, 1972.
30. Etoh, K., Kaketani, K., Saito, T., Uchino, S., Shimoda, K., Miyahara, M., and Kobayashi, M. DNA stem-line heterogeneity as preoperative prognostic factor in esophageal cancer. Gan to Kagakn Ryoho, 21: 1-5, 1994.
31. Johnson, H., Jr., Belluco, C., Masood, S., Abou-Azama, A. M., Kahn, L., and Wise, L. The value of flow cytometric analysis in patients with gastric cancer. Arch. Surg., 128: 314-317, 1993.
32. Danova, M., Riccardi, A., Mazzini, G., Wilson, G., Dionigi, P., Brugnatelli, S., Fiocca, R., Ucci, G., Jemos, V., and Ascari, E. Flow cytometric analysis of paraffin-embedded material in human gastric cancer. Anal. Quant. Cytol. Histol., 10: 200-206, 1988.
33. Nanus, D. M., Kelsen, D. P., Niedzwiecki, D., Chapman, D., Brennan, M., Cheng, E., and Melamed, M. Flow cytometry as a predictive indicator in patients with operable gastric cancer. J. Clin. Oncol., 7: 1105-1112, 1989.
34. Scaddan, P. B., and Dufresne, M. J. Characterization of cysteine proteases and their endogenous inhibitors in MCF-7 and Adriamycin-resistant MCF-7 human breast cancer lines. Invasion Metastasis, 13: 301-313, 1993.
35. Sun, Q. Growth stimulation of 3T3 fibroblast by cystatin. Exp. Cell. Res., 180: 150-160, 1989.
36. Chambers, A., Colella, R., Denhardt, D. T., and Wilson, S. Increased expression of cathepsin L and B and decreased activity of their inhibitors in metastatic ras transformed NIH 3T3 cells. Mol. Carcinog., 5: 238-245, 1992.
37. Schwartz, G. K., Wang, H., Lampen, N., Altorki, N., Kelsen, D., and Albino, A. P. Defining the invasive phenotype of proximal gastric cancer cells. Cancer (Phila.), 73: 22-27, 1994.