Molecular characterization of a new variant of toxin-coregulated pilus protein (TcpA) in a toxigenic non-O1/non-O139 strain of Vibrio cholerae

Infection and Immunity

Volumn 68, Issue 2, 2000, Pages 948-952

  Nandi, Bisweswar ^a   Nandy, Ranjan K ^a   Vicente, Ana C P ^b   Ghose, Asoke C ^a  

^a BOSE INSTITUTE   (India)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; DNA;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM PILUS; CHOLERA; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; STRAIN DIFFERENCE; TOXIN ANALYSIS; VIBRIO; VIBRIO CHOLERAE;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; BASE SEQUENCE; FIMBRIAE PROTEINS; FIMBRIAE, BACTERIAL; IMMUNE SERA; MICE; MOLECULAR SEQUENCE DATA; RABBITS; VIBRIO CHOLERAE;

EID: 0033978079     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.2.948-952.2000     Document Type: Article

References (29)

1. Bik, E. M., R. D. Gouw, and F. R. Mooi. 1996. DNA fingerprinting of Vibrio cholerae strains with a novel insertion sequence element: a tool to identify epidemic strains. J. Clin. Microhiol. 34:1453-1461.
2. Chiang, S. L., R. K. Taylor, M. Koomey, and J. J. Mekalanos. 1995. Single amino acid substitutions in the N-terminus of Vibrio cholerae TcpA affect colonization, autoagglutination, and serum resistance. Mol. Microbiol. 17: 1133-1142.
3. Datta-Roy, K., K. Banerjee, S. P. De, and A. C. Ghose. 1986. Comparative study of expression of hemagglutinins, hemolysins, and enterotoxins by clinical and environmental isolates of non-O1 Vibrio cholerae in relation to their cnteropathogenicity. Appl. Environ. Microbiol. 52:875-879.
4. Ghosh, C., R. K. Nandy, S. K. Dasgupta, G. B. Nair, R. H. Hall, and A. C. Ghose. 1997. A search for cholera toxin (CT), toxin coregulated pilus (TCP), the regulatory element ToxR and other virulence factors in non-O1/non-O139 Vibrio cholerae. Microb. Pathog. 22:199-208.
5. Hall, R. H., F. M. Khambaty, M. Kothary, and S. P. Keasler. 1993. Non-O1 Vibrio cholerae. Lancet 342:430.
6. Iredell, J. R., and P. A. Manning. 1994. Biotype-specific tcpA genes in Vibrio cholerae. FEMS Microbiol. Lett. 121:47-54.
7. Jonson, G., J. Holmgren, and A. M. Svennerholm. 1991. Epitope differences in toxin-coregulated pili produced by classical and El Tor Vibrio cholerae O1. Microb. Pathog. 11:179-188.
8. Jonson, G., J. Holmgren, and A. M. Svennerholm. 1992. Analysis of expression of toxin-coregulated pili in classical and El Tor Vibrio cholerae O1 in vitro and in vivo. Infect. Immun. 60:4278-4284.
9. Karaolis, D. K. R., J. A. Johnson, C. C. Bailey, E. C. Boedeker, J. B. Kaper, and P. R. Reeves. 1998. A Vibrio cholerae pathogenicity island associated with epidemic and pandemic strains. Proc. Natl. Acad. Sci. USA 95:3134-3139.
10. Karaolis, D. K. R., S. Somara, D. R. Maneval, Jr., J. A. Johnson, and J. B. Kaper. 1999. A bacteriophage encoding a pathogenicity island, a type-IV pilus and a phage receptor in cholera bacteria. Nature 399:375-379.
11. Kaufman, M. R., C. E. Shaw, I. D. Jones, and R. K. Taylor. 1993. Biogenesis and regulation of the Vibrio cholerae toxin-coregulated pilus: analogies to other virulence factor secretory systems. Gene 126:43-49.
12. Keasler, S. P., and R. H. Hall. 1993. Detecting and biotyping Vibrio cholerae O1 with multiplex polymerase chain reaction. Lancet 341:1661.
13. Mekalanos, J. J. 1983. Duplication and amplification of toxin genes in Vibrio cholerae. Cell 35:253-263.
14. Meyer, T. F., C. P. Gibbs, and R. Hass. 1990. Variation and control of protein expression in Neisseria. Annu. Rev. Microbiol. 44:451-477.
15. Morris, J. G., Jr. 1994. Non-O group 1 Vibrio cholerae strains not associated with epidemic disease, p. 103-115. In I. K. Wachsmuth, P. A. Blake, and O. Olsvik (ed.), Vibrio cholerae and cholera: molecular to global perspectives. ASM Press, Washington, D.C.
16. Nandy, R. K., T. K. Sengupta, S. Mukhopadhyay, and A. C. Ghose. 1995. A comparative study of the properties of Vibrio cholerae O139, O1 and other non-O1 strains. J. Med. Microbiol. 42:251-257.
17. Novais, R. C., A. Coelho, C. A. Salles, and A. C. Vicente. 1999. Toxin-coregulated pilus cluster in non-O1, non-toxigenic Vibrio cholerae: evidence of a third allele of pilin gene. FEMS Microhiol. Lett. 171:49-55.
18. Ogierman, M. A., S. Zabihi, L. Mourtzios, and P. A. Manning. 1993. Genetic organization and sequence of the promoter-distal region of the tcp gene cluster of Vibrio cholerae. Gene 126:51-60.
19. Peek, J. A., and R. K. Taylor. 1992. Characterization of a periplasmic thiol: disulphide interchange protein required for the functional maturation of secreted virulence factors of Vibrio cholerae. Proc. Natl. Acad. Sci. USA 89: 6210-6214.
20. Rhine, J. A., and R. K. Taylor. 1994. TcpA pilin sequences and colonization requirements for O1 and O139 Vibrio cholerae. Mol. Microbiol. 13:1013-1020.
21. Said, B., H. R. Smith, S. M. Scotland, and B. Rowe. 1995. Detection and differentiation of the gene for toxin co-regulated pili (tcpA) in Vibrio cholerae non-O1 using the polymerase chain reaction. FEMS Microbiol. Lett. 125: 205-210.
22. Sengupta, T. K. 1995. Identification and immunological characterisation of cell surface proteins responsible for intestinal adhesion and colonization of diarrhoeagenic non-O1 Vibrio cholerae. Ph.D. thesis. University of Calcutta, Calcutta, India.
23. Shaw, C. E., and R. K. Taylor. 1990. Vibrio cholerae O395 tcpA pilin gene sequence and comparison of predicted protein structural features to those of type 4 pilins. Infect. Immun. 58:3042-3049.
24. Sun, D., M. J. Lafferty, J. A. Peek, and R. K. Taylor. 1997. Domains within Vibrio cholerae toxin coregulated pilin subunit that mediate bacterial colonization. Gene 192:79-85.
25. Sun, D., J. M. Seyer, I. Kovari, R. A. Sumrada, and R. K. Taylor. 1991. Localization of protective epitopes within the pilin subunit of the Vibrio cholerae toxin-coregulated pilus. Infect. Immun. 59:114-118.
26. Taylor, R., C. Shaw, K. Peterson, P. Spears, and J. Mekalanos. 1988. Safe, live Vibrio cholerae vaccines? Vaccine 6:151-154.
27. Taylor, R. K., V. L. Miller, D. B. Furlong, and J. J. Mekalanos. 1987. Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. Proc. Natl. Acad. Sci. USA 84:2833-2837.
28. Voss, E., and S. R. Attridge. 1993. In vitro production of toxin-coregulated pili by Vibrio cholerae El Tor. Microb. Pathog. 15:255-268.
29. Waldor, M. K., and J. J. Mekalanos. 1996. Lysogenic conversion by a filamentous phage encoding cholera toxin. Science 272:1910-1914.