Effects of changes in dietary intake of sodium and potassium and of metabolic acidosis on 11β-hydroxysteroid dehydrogenase activities in rat kidney

Experimental Nephrology

Volumn 8, Issue 1, 2000, Pages 44-51

  Thompson, Anna ^a   Bailey, Matthew A ^a   Michael, Anthony E ^a   Unwin, Robert J ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

11 Hydroxysteroid dehydrogenase; Acid base balance; Glucocorticoids; Kidney; Potassium; Sodium

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ALDOSTERONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; MINERALOCORTICOID RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; POTASSIUM; SODIUM;

ACID BASE BALANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET; ENZYME ACTIVITY; FOOD INTAKE; KIDNEY; KIDNEY FUNCTION; METABOLIC ACIDOSIS; NEPHRON; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT;

EID: 0033978042     PISSN: 10187782     EISSN: None     Source Type: Journal    
DOI: 10.1159/000020647     Document Type: Article

References (29)

1. Krozowski ZS, Funder JW: Renal mineralocorticoid receptors and hippocampal corticosteroid-binding species have identical intrinsic steroid specificity. Proc Natl Acad Sci USA 1983;80:6056-6060.
2. Sheppard K, Funder JW: Type 1 receptors in parotid, colon, and pituitary are aldosterone selective in vivo. Am J Physiol 1987;253: E467-E471.
3. Funder JW, Pearce PT, Myles K, Roy LP: Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: Toward a new definition of mineralocorticoid action. FASEB J 1990;4:3234-3238.
4. Funder JW, Pearce PT, Smith AI: Mineralocorticoid action: Target tissue specificity is enzyme, not receptor mediated. Science 1988; 241:583-585.
5. Edwards CRW, Stewart PM, Burt D, Brett L, McIntyre MA, Sutanto WS, Dekloet ER, Monder C: Localization of 11β-hydroxysteroid dehydrogenase tissue specific protector of the mineralocorticoid receptor. Lancet 1988;ii: 986-989.
6. +-dependent isoform of 11β-hydroxysteroid dehydrogenase: Cloning and characterization of cDNA from sheep kidney. J Biol Chem 1994;269:25959-25962.
7. Albiston AL, Obeyesekere VR, Smith RE, Krozowski ZS: Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol 1994;105: R11-R17.
8. Bonvalet J-P, Doignon I, Blot-Chabaud M, Pradelles P, Farman N: Distribution of 11β-hydroxysteroid dehydrogenase along the rabbit nephron. J Clin Invest 1990;86:832-837.
9. Mune T, Rogerson FM, Nikkila H, Agarwal AK, White PC: Human hypertension caused by mutations in the kidney isoform of 11β-hydroxysteroid dehydrogenase. Nat Genet 1995; 10:394-399.
10. White PC, Mune T, Agarwal AK: 11β-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. Endocr Rev 1997;18:136-156.
11. Souness GW, Morris DJ: The antinatriuretic and kaliuretic effects of the glucocorticoids corticosterone and cortisol following pre-treatment with carbenoxolone sodium (a liquorice derivative) in the adrenalectomized rat. Endocrinology 1989;124:1588-1590.
12. Stewart PM, Wallace AM, Atherden SM, Shearing CH, Edwards CRW: Mineralocorticoid activity of carbenoxolone: Contrasting effects of carbenoxolone and liquorice on 11β-hydroxysteroid dehydrogenase activity in man. Clin Sci 1990;78:48-54.
13. Cogan MG: Acid-base homeostasis and disorders; in: Fluids and Electrolytes. San Francisco, Appleton & Lange, 1991, p 175.
14. Kurtzman NA, Gonzalez J, De Fronzo R, Giebisch G: A patient with hyperkalemia and metabolic acidosis. Am J Kidney Dis 1990;15: 333-356.
15. Laragh JH, Sealey JE: Renin-angiotensin-aldosterone system and renal regulation of sodium, potassium and blood pressure homeostasis; in Windhager EE (ed): Handbook of Physiology. New York, Oxford University Press, 1992, pp 1409-1542.
16. Sewell KJ, Shirley DG, Michael AE, Thompson A, Norgate DP, Unwin RJ: In vivo inhibition of renal 11β-hydroxysteroid dehydrogenase: Relationship to sodium excretion. Clin Sci 1998;95:435-443.
17. Rusvai E, Naray-Fejes-Toth A: A new isoform of 11β-hydroxysteroid dehydrogenase in aldosterone target cells. J Biol Chem 1993;268: 10717-10720.
18. Wright FS, Giebisch G: Regulation of potassium excretion; in Seldin DW, Giebisch G (eds): The Kidney: Physiology and Pathophysiology. New York, Raven Press, 1985, pp 1223-1249.
19. Lang F, Rehwald W: Potassium channels in renal epithelial transport regulation. Physiol Rev 1992;72:1-32.
20. Eiam-Ong S, Kurtzman S, Sabatini S: Regulation of collecting tubule adenosine triphosphatases by aldosterone and potassium. J Clin Invest 1993;91:2385-2392.
21. Rafestin-Oblin ME, Claire M, Lombes M, Michaud A: Modulation of aldosterone receptors in rat kidney: Effects of steroid treatment and potassium diet. J Steroid Biochem 1984;21: 465-470.
22. Brem AS, Bina RB, King T, Chobanian MC, Morris DJ: Influence of dietary sodium on the renal isoforms of 11 beta-hydroxysteroid dehydrogenase. Proc Soc Exp Biol Mcd 1997;241: 340-345.
23. Nolan PJ, Knepper MA, Packer RK: Inhibition of IMCD 11β-hydroxysteroid dehydrogenase type 2 by low pH and acute acid-loading. J Am Soc Nephrol 1997;8:530-534.
24. Alfaidy N, Blot-Chabaud M, Bonvalet J-P, Farman N: Vasopressin potentiates mineralocorticoid selectivity by stimulating 11β-hydroxysteroid dehydrogenase in rat collecting duct. J Clin Invest 1997;100:2437-2462.
25. + secretion in rat CCD. Am J Physiol 1990;258:F199-F210.
26. Morris DJ, Latif SA, Sheff MF, Abrampah K, Litchfield WR, Williams GH: Urinary levels of kidney 11β(HSD2)-GALFs in patients with essential hypertension correlate with plasma renin activity (PRA). Proc 80th Meet Endocrine Soc 1998, New Orleans, pp 2-365.
27. Monder C, Lakshmi V: Evidence for kinetically distinct forms of corticosteroid 11 beta-dehydrogenase in rat liver microsomes. J Steroid Biochem 1989;32:77-83.
28. Lakshmi V, Nath N, Muneyyirci-Delale O: Characterization of 11 beta-hydroxysteroid dehydrogenase of human placenta: Evidence for the existence of two species of 11 beta-hydroxysteroid dehydrogenase. J Steroid Biochem Mol Biol 1993;45:391-397.
29. + depletion in rats. Am J Physiol 1986;251:F904-F910.