Identification of unexpected modifications of fluorescein-labeled oligodeoxynucleotides by nuclease P1 digestion and mass spectrometric techniques

Rapid Communications in Mass Spectrometry

Volumn 14, Issue 1, 2000, Pages 26-32

  Wu, Huaiqin ^a   Skrzypczynski, Zbigniew ^a   Cornwell, Michael J ^a   Aboleneen, Hoda ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL MODIFICATION; ENZYMIC DEGRADATION; FLUORESCEIN; FLUORESCENT LABELING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERIZATION; MASS SPECTROMETRY; NUCLEASE P1; OLIGODEOXYNUCLEOTIDE; SYNTHESIS;

CHEMICAL MODIFICATION; CHROMATOGRAPHIC ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERS; MASS SPECTROMETERS; NUCLEOTIDES; THIOUREAS;

AUTOMATED SYNTHESIS; COLLISION-INDUCED DISSOCIATION SPECTRA; DIGESTION PRODUCTS; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; MULTIPLE-PEAK; NUCLEASE P1; OLIGODEOXYNUCLEOTIDES; PHOSPHATE GROUP; SPECTROMETRIC TECHNIQUES; SYNTHESISED;

MASS SPECTROMETRY;

EID: 0033977132     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0231(20000115)14:1<26::AID-RCM827>3.0.CO;2-P     Document Type: Article

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