Pilot MR evaluation of pharmacokinetics and relaxivity of specific blood pool agents for MR angiography

Investigative Radiology

Volumn 35, Issue 1, 2000, Pages 41-49

  Marchand, Bruno ^a   Douek, Philippe C ^a   Benderbous, Soraya ^b   Corot, Claire ^b   Canet, Emmanuelle ^a  

^a UNIVERSITÉ DE LYON   (France)

^b Laboratoire Guerbet   (France)

Author keywords

Contrast agent; Experimental study; MR angiography

Indexed keywords

CONTRAST MEDIUM; GADOLINIUM CHELATE; GADOTERIC ACID; P 760; P 775; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD POOL SCINTISCANNING; CONTRAST ENHANCEMENT; DOSE RESPONSE; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; FIRST PASS EFFECT; MAGNETIC RESONANCE ANGIOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RABBIT;

EID: 0033976954     PISSN: 00209996     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004424-200001000-00005     Document Type: Article

References (32)

1. Creasy JL, Price RR, Presbrey T, Goins D, Partain CL, Kessler RM. Gadolinium-enhanced MR angiography. Radiology 1990;175:280-283.
2. Dong Q, Hurst DR, Weinmann HJ, Chenevert TL, Londy FJ, Prince MR. Magnetic resonance angiography with gadomer-17: An animal study original investigation. Invest Radiol 1998;33:699-708.
3. Baum RA, Rutter CM, Sunshine JH, et al. Multicenter trial to evaluate vascular magnetic resonance angiography of the lower extremity. American College of Radiology Rapid Technology Assessment Group. JAMA 1995;274:875-880.
4. Price RR, Creasy JL, Lorenz CH, Partain CL. Magnetic resonance angiography techniques. Invest Radiol 1992;27(Suppl 2):S27-S32.
5. Yucel EK, Kaufman JA, Geller SC, Waltman AC. Atherosclerotic occlusive disease of the lower extremity: Prospective evaluation with two-dimensional time-of-flight MR angiography [see comments]. Radiology 1993;187:637-641.
6. Douek PC, Revel D, Chazel S, Falise B, Villard J, Amiel M. Fast MR angiography of the aortoiliac arteries and arteries of the lower extremity: Value of bolus-enhanced, whole-volume subtraction technique. Am J Roentgenol 1995;165:431-437.
7. Prince MR, Narasimham DL, Stanley JC, et al. Breath-hold gadolinium-enhanced MR angiography of the abdominal aorta and its major branches. Radiology 1995;197:785-792.
8. Loubeyre P, Revel D, Douek P, et al. Dynamic contrast-enhanced MR angiography of pulmonary embolism: Comparison with pulmonary angiography. Am J Roentgenol 1994;162:1035-1039.
9. Snidow JJ, Johnson MS, Harris VJ, et al. Three-dimensional gadolinium-enhanced MR angiography for aortoiliac inflow assessment plus renal artery screening in a single breath hold. Radiology 1996;198:725-732.
10. Revel D, Loubeyre P, Delignette A, Douek P, Amiel M. Contrastenhanced magnetic resonance tomoangiography: A new imaging technique for studying thoracic great vessels. J Magn Reson Imaging 1993;11:1101-1105.
11. Bourne MW, Margerun L, Hylton N, et al. Evaluation of the effects of intravascular MR contrast media (gadolinium dendrimer) on 3D time-of-flight magnetic resonance angiography of the body. J Magn Reson Imaging 1996;6:305-310.
12. Loubeyre P, Canet E, Zhao S, Benderbous S, Amiel M, Revel D. Carboxymelhyl-dextran-gadolinium-DTPA as a blood-pool contrast agent for magnetic resonance angiography: Experimental study in rabbits. Invest Radiol 1996;31:288-293.
13. Marchal G, Bosmans H, Van Hecke P, et al. MR angiography with gadopentetate dimeglumine-polylysine: Evaluation in rabbits. Am J Roentgenol 1990;155:407-411.
14. Moseley ME, White DL, Wang SC, et al. Vascular mapping using albumin-(Gd-DTPA), an intravascular MR contrast agent, and projection MR imaging. J Comput Assist Tomogr 1989;13:215-221.
15. Adam G, Neuerburg J, Spuntrup E, Muhler A, Scherer K, Gunther RW. Gd-DTPA-cascade-polymer: Potential blood pool contrast agent for MR imaging. J Magn Reson Imaging 1994;4:462-466.
16. Bogdanov AA Jr, Weissleder R, Frank HW, et al. A new macromolecule as a contrast agent for MR angiography: Preparation, properties, and animal studies. Radiology 1993;187:701-706.
17. Schmiedl U, Brasch RC, Ogan MD, Moseley ME. Albumin labeled with Gd-DTPA: An intravascular contrast-enhancing agent for magnetic resonance blood pool and perfusion imaging. Acta Radiol Suppl 1990;374:99-102.
18. Schuhmann-Giampieri G, Schmitt-Willich H, Frenzel T, Press WR, Weinmann HJ. In vivo and in vitro evaluation of Gd-DTPA-polylysine as a macromolecular contrast agent for magnetic resonance imaging. Invest Radiol 1991;26:969-974.
19. Schwickert HC, Roberts TP, Muhler A, Stiskal M, Demsar F, Brasch RC. Angiographie properties of Gd-DTPA-24-cascade-polymer: A new macromolecular MR contrast agent. Eur J Radiol 1995;20: 144-150.
20. Loubeyre P, Zhao S, Canet E, Abidi H, Benderbous S, Revel D. Ultrasmail superparamagnetic iron oxide particles (AMI 227) as a blood pool contrast agent for MR angiography: Experimental study in rabbits. J Magn Reson Imaging 1997;7:958-962.
21. Mayo-Smith WW, Saini S, Slater G, Kaufman JA, Sharma P, Hahn PF. MR contrast material for vascular enhancement: Value of superparamagnetic iron oxide [see comments]. Am J Roentgenol 1996; 166:73-77.
22. Tanimoto A, Yuasa Y, Hiramatsu K. Enhancement of phase-contrast MR angiography with superparamagnetic iron oxide. J Magn Reson Imaging 1998;8:446-450.
23. Engelbrecht MR, Saeed M, Wendland MF, Canet E, Oksendal AN, Higgins CB. Contrast-enhanced 3D-TOF MRA of peripheral vessels: Intravascular versus extracellular MR contrast media. J Magn Reson Imaging 1998;8:616-621.
24. Lauffer RB, Parmelee DJ, Dunham SU, et al. MS-325: Albumintargeted contrast agent for MR angiography. Radiology 1998;207: 529-538.
25. Parmelee DJ, Walovitch RC, Quellet HS, Lauffer RB. Preclinical evaluation of the pharmacokinetics, biodistribution, and elimination of MS-325, a blood pool agent for magnetic resonance imaging. Invest Radiol 1997;32:741-747.
26. Kroft LJ, Doornbos J, van der Geest RJ, Benderbous S, de Roos A. Infarcted myocardium in pigs: MR imaging enhanced with slowinterstitial-diffusion gadolinium compound P760. Radiology 1999; 212:467-473.
27. Corot C, Port M, Raynal I, et al. Physical, chemical and biological evaluations of P760: A new gadolinium complex characterized by a low rate of interstitial diffusion. J Magn Reson Imaging 1999 In press.
28. Port M, Meyer D, Bonnemain B, et al. P760 and P775: MRI contrast agents characterized by new pharmacokinetic properties. MAGMA 1999 In press.
29. Fukuda Y, Watanabe H, Tomita T, Katayama H, Miyano T, Yabuta K. Evaluation of glomerular function in individual kidneys using dynamic magnetic resonance imaging. Pediatr Radiol 1996;26:324-328.
30. Brasch RC, Weinmann HJ, Wesbey GE. Contrast-enhanced NMR imaging: Animal studies using gadolinium-DTPA complex. Am J Roentgenol 1984;142:625-630.
31. Kopka L, Vosshenrich R, Rodenwaldt J, Grabbe E. Differences in injection rates on contrast-enhanced breath-hold three-dimensional MR angiography. Am J Roentgenol 1998;170:345-348.
32. Boos M, Lentschig M, Scheffler K, Bongartz GM, Steinbrich W. Contrast-enhanced magnetic resonance angiography of peripheral vessels: Different contrast agent applications and sequence strategies: A review. Invest Radiol 1998;33:538-546.