Novel Inhibitors of the Nuclear Factor of Activated T Cells (NFAT)-Mediated Transcription of β-Galactosidase: Potential Immunosupressive and Antiinflammatory Agents

Journal of Medicinal Chemistry

Volumn 38, Issue 14, 1995, Pages 2557-2569

  Michne, William F ^a   Schroeder, Joseph D ^a   Guiles, Joseph W ^a   Treasurywala, Adi M ^a   Weigelt, Carolyn A ^a   Stansberry, Mary F ^a   McAvoy, Elizabeth ^a   Shah, Chandra R ^a   Baine, Yaela ^a   Sawutz, David G ^a   Miller, Persymphonie B ^a   Stankunas, Bonnie M ^a   Reid, John ^a   Bump, Elizabeth ^a   Schlegel, Donald ^a  

^a EASTMAN KODAK COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYL 1 (2 METHYLPROPYL) 6 (1 NAPHTHYLMETHYL)PYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; 6 [(2 CHLOROPHENYL)METHYL] 3 METHYL 1 (2 METHYLPROPYL)PYRROLO[3,4 D]PYRIMIDINE 2,4 DIONE; ANTIINFLAMMATORY AGENT; BETA GALACTOSIDASE INHIBITOR; IMMUNOSUPPRESSIVE AGENT; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG CONFORMATION; DRUG POTENCY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BETA-GALACTOSIDASE; CELL LINE; DNA-BINDING PROTEINS; HUMAN; IMMUNOSUPPRESSIVE AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0029050389     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00014a009     Document Type: Article

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