Induction of microthrombotic thrombocytopenia in normal mice by transferring a platelet-reactive, monoclonal anti-gp70 autoantibody established from MRL/lpr mice: An autoimmune model of thrombotic thrombocytopenic purpura

Clinical and Experimental Immunology

Volumn 119, Issue 1, 2000, Pages 47-56

  Hashimoto, K ^a,b   Tabata, N ^a   Fujisawa, R ^b,c   Matsumura, H ^a   Miyazawa, M ^a,b,c  

^a Department of Immunology ^*  (Japan)

^b KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Autoantibody; gp70; MRL lpr; Platelet; Thrombocytopenia

Indexed keywords

AUTOANTIBODY; GENE PRODUCT; GLYCOPROTEIN; GLYCOPROTEIN GP 70; PHOSPHOLIPID ANTIBODY; THROMBOCYTE ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY PRODUCING CELL; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; GLOMERULONEPHRITIS; HISTOPATHOLOGY; MICROTHROMBUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; THROMBOCYTOPENIA; THROMBOTIC THROMBOCYTOPENIC PURPURA;

ANIMALS; ANTIBODIES, MONOCLONAL; AUTOANTIBODIES; BLOOD PLATELETS; CELL LINE; FEMALE; FRIEND MURINE LEUKEMIA VIRUS; GLOMERULONEPHRITIS; HYBRIDOMAS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN G; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED MRL LPR; PLATELET AGGREGATION; PURPURA, THROMBOTIC THROMBOCYTOPENIC; VIRAL ENVELOPE PROTEINS;

EID: 0033969778     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2000.01116.x     Document Type: Article

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