Cytokine cascade induced by endotoxin in TNF double receptor knockout mice: Evidence supporting a role for IL-10 in mediating antipyretic action of TNF

Journal of Thermal Biology

Volumn 25, Issue 1-2, 2000, Pages 21-27

  Gourine, A V ^a   Leon, L R ^a   Rudolph, K ^a   Tesfaigzi, J ^a   Kluger, M J ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

Antipyresis; Cytokines; Fever; Gene deletion; Interleukin 10; Knockout mice; Lipopolysaccharide; Temperat ure regulation; Tumor necrosis factor

Indexed keywords

EID: 0033968359     PISSN: 03064565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4565(99)00051-0     Document Type: Conference Paper

References (34)

1. Aarden L.A., de Groot E.R., Schaap O.L., Lansdorp P.M. Production of hybridoma growth factors by human monocytes. Eur. J. Immunol. 17:1987;1411-1416.
2. Amiot F., Fitting C., Tracey K.J., Cavaillon J.M., Dautry F. Lipopolysaccharide-induced cytokine cascade and lethality in LTα/TNFα-deficient mice. Mol. Med. 3:1997;864-875.
3. Barsig J., Kusters S., Vogt K., Volk H-D., Tiegs G., Wendel A. Lipopolysaccharide-induced interleukin-10 in mice: role of endogenous tumor necrosis factor-α Eur. J. Immunol. 25:1995;2888-2893.
4. Colotta F., Re F., Muzio M., Bertini R., Polentarutti N., Sironi M., Giri J.G., Dower S.K., Sims J.E., Mantovani A. Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4. Science. 261:1993;472-475.
5. Cooper A.L., Brouwer S., Turnbull A.V., Luheshi G.N., Hopkins S.J., Kunkel S.L., Rothwell N.J. Tumor necrosis factor-α and fever after peripheral inflammation in the rat. Am. J. Physiol. 267:1994;R1431-R1436.
6. Daftarian P.M., Kumar A., Kryworuchko M., Diaz-Mitoma F. IL-10 production is enhanced in human T cells by IL-12 and IL-6 and in monocytes by TNFα J. Immunol. 157:1996;12-20.
7. de Waal Malefyt R., Abrams J., Bennett B., Figdor C.G., de Vries J.E. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174:1991;1209-1220.
8. Fiorentino D.F., Bond M.W., Mosmann T.R. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 170:1989;2081-2095.
9. Fiorentino D.F., Zlotnik A., Mosmann T.R., Howard M., O'Garra A. IL-10 inhibits cytokine production by activated macrophages. J. Immunol. 147:1991;3815-3822.
10. Gerard C., Bruyns C., Marchant A., Abramowicz D., Vandenabeele P., Delvaux A., Fiers W., Goldman M., Velu T. Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J. Exp. Med. 177:1993;547-550.
11. Goldbach J.M., Roth J., Storr B., Zeisberger E. Influence of pentoxifylline on fevers induced by bacterial lipopolysaccharide and tumor necrosis factor-α in guinea-pigs. Eur. J. Pharmacol. 319:1997;273-278.
12. Kapas L., Hong L., Cady A.B., Opp M.R., Postlethwaite A.E., Seyer J., Krueger J.M. Somnogenic, pyrogenic, and anorectic activities of tumor necrosis factor-α and TNF-α fragments. Am. J. Physiol. 263:1992;R708-R715.
13. Kawasaki H., Moriyama M., Ohtani Y., Naitoh M., Tanaka A., Nariuchi H. Analysis of endotoxin fever in rabbits by using a monoclonal antibody to tumor necrosis factor (cachectin). Infect. Immunol. 57:1989;3131-3135.
14. Klir J.J., McClellan J.L., Kozak W., Szelenyi Z., Wong G.H.W., Kluger M.J. Systemic but not central administration of tumor necrosis factor-α attenuates LPS-induced fever in rats. Am. J. Physiol. 268:1995;R480-R486.
15. Klir, J.J., Roth, J., Szelényi, Z., McClellan, J.L., Kluger, M.J., Role of hypothalamic interleukin-6 and tumor necrosis factor-α in LPS fever in rat, Am. J. Physiol. 265 R512-R517.
16. Kluger M.J. Fever: role of pyrogens and cryogens. Physiol. Rev. 71:1991;93-127.
17. Kluger M.J., Kozak W., Leon L., Conn C. The use of knockout mice to understand the role of cytokines in fever. Clin. Exp. Pharmacol. Physiol. 25:1998;141-144.
18. Kluger M.J., Kozak W., Leon L., Soszynski D., Conn C. Cytokines and fever. Neuroimmunomodulation. 2:1995;216-223.
19. Kozak W., Conn C.A., Klir J.J., Wong G.H.W., Kluger M.J. TNF soluble receptor and antiserum against TNF enhance lipopolysaccharide fever in mice. Am. J. Physiol. 269:1995;R23-R29.
20. Kwiatkowski D., Molyneux M.E., Stephens S., Curtis N., Klein N., Pointaire P., Smit M., Allan R., Brewster D.R., Grau G.E., Greenwood B.M. Anti-TNF therapy inhibits fever in cerebral malaria. Q. J. Med. 86:1993;91-98.
21. Leon L.R., Kozak W., Peschon J., Kluger M.J. Exacerbated febrile responses to LPS, but not turpentine, in TNF double receptor-knockout mice. Am. J. Physiol. 272:1997;R563-R569.
22. Leon L.R., Kozak W., Kluger M.J. An antipyretic role for interleukin-10 in LPS fever. Am. J. Physiol. 276:1998;R81-R89.
23. Long N.C., Kunkel S.L., Vander A.J., Kluger M.J. Antiserum against tumor necrosis factor enhances lipopolysaccharide fever in rats. Am. J. Physiol. 258:1990;R332-R337.
24. Long N.C., Otterness I.G., Kunkel S.L., Vander A.J., Kluger M.J. Role of interleukin-1β and tumor necrosis factor in lipopolysaccharide fever in rats. Am. J. Physiol. 259:1990;R724-R728.
25. Marchant A., Amraoui Z., Gueydan C., Bruyns C., Le Moine O., Vandenabeele P., Fiers W., Buurman W.A., Goldman M. Methylprednisolone differentially regulates IL-10 and tumor necrosis factor (TNF) production during murine endotoxaemia. Clin. Exp. Immunol. 106:1996;91-96.
26. Nagai M., Saigusa T., Shimada Y., Inagawa H., Oshima H., Iriki M. Antibody to tumor necrosis factor (TNF) reduces endotoxin fever. Experientia. 44:1988;606-607.
27. Nava F., Calapai G., Facciola G., Cuzzocrea S., Marciano M.C., DeSarro A., Caputi A.P. Effects of interleukin-10 on water intake, locomotory activity and rectal temperature in rats treated with endotoxin. Int. J. Immunopharmacol. 19:1997;31-38.
28. Orlando S., Matteucci C., Fadlon E.J., Buurman W.A., Bardella M.T., Colotta F., Introna M., Mantovani A. TNF-α, unlike other pro- and anti-inflammatory cytokines, induces rapid release of the IL-1 type II decoy receptor in human myelomonocytic cells. J. Immunol. 158:1997;3861-3868.
29. Peschon J.J., Torrance D.S., Stocking K.L., Glaccum M.B., Otten C., Willis C.R., Charrier K., Morrissey P.J., Ware C.B., Mohler K.M. TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation. J. Immunol. 160:1998;943-952.
30. Quan N., Zhang Z., Emely M., Bonsall R., Weiss J.M. Detection of interleukin-1 bioactivity in various brain regions of normal healthy rats. Neuroimmunomodulation. 3:1996;47-55.
31. Roth J., Martin D., Storr B., Zeisberger E. Neutralization of pyrogen-induced tumour necrosis factor by its type 1 soluble receptor in guinea-pigs: effects on fever and interleukin-6 release. J. Physiol. 509:1998;267-275.
32. Roth J., McClellan J.L., Kluger M.J., Zeisberger E. Changes in body temperature and circulating levels of interleukin-6 after intra-arterial injections or infusions of tumor necrosis factor-α in guinea-pigs. Experientia. 50:1994;815-820.
33. van der Poll T., Jansen J., Levi M., ten Cate H., Wouter ten Cate J., van Deventer S.J.H. Regulation of interleukin-10 release by tumor necrosis factor in humans and chimpanzees. J. Exp. Med. 180:1994;1985-1988.
34. Wanidworanum C., Strober W. Predominant role of tumor necrosis factor-α in human monocyte IL-10 synthesis. J. Immunol. 151:1993;6853-6861.